mPEG-icariin nanoparticles for treating myocardial ischaemia

References

• Laslett LJ, Alagona P, Clark BA, et al. The worldwide environment of cardiovascular disease: prevalence, diagnosis, therapy, and policy issues: A report from the american college of cardiology. J Am Coll Cardiol. 2012;60:S1–S49.
   PubMed Web of Science ®Google Scholar
• Huang H, Yao QY, Xia EH, et al. Metabolomics and transcriptomics analyses reveal nitrogen influences on the accumulation of flavonoids and amino acids in young shoots of tea plant (Camellia sinensis L.) associated with tea flavor. J Agric Food Chem 2018;17:158–170.
   Google Scholar
• Zhang WD, Chen H, Zhang C, et al. Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro. Planta Med. 2006;72:4–8.
   PubMed Web of Science ®Google Scholar
• Liu HJ, Liu XY, Jing DB. Icariin induces the growth, migration and osteoblastic differentiation of human periodontal ligament fibroblasts by inhibiting Toll-like receptor 4 and NF-κB p65 phosphorylation. Mol Med Rep. 2018;18:3325–3331.
   PubMed Web of Science ®Google Scholar
• Liu SY, Wu HJ. Research progress of icariin pharmacologic action. Med Recapit 2009;6:909–912.
   Google Scholar
• Wang Z, Wang D, Yang D, et al. The effect of icariin on bone metabolism and its potential clinical application. Osteoporos Int. 2018; 29:535–544.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Sai LI, Ding XS. Effect of icariin on the vasodilation function of renal artery in diabetic nephropathy rats. Pharm Clin Res. 2016;3:209–211.
   Google Scholar
• Zhang L, Zhang X, Li KF, et al. Icariin promotes extracellular matrix synthesis and gene expression of chondrocytes in vitro. Phytother Res. 2012;26:1385–1392.
   PubMed Web of Science ®Google Scholar
• Xu S, Yu J, Zhan J, et al. Pharmacokinetics, tissue distribution, and metabolism study of icariin in rat. Biomed Res Int. 2017;9:4684–4702.
   Google Scholar
• Jia LL, Yuan D, Wang HW, et al. The pharmacological research advance of icariin. Prog Mod Biomed. 2010;20:3976–3979.
   Google Scholar
• Gao M, Ma FF, Wu SH, et al. Research advance in the pharmacological effects of icariin. Med Plant. 2013;1:79–82.
   Google Scholar
• Yan H, Zhou Z, Huang T, et al. Controlled release in vitro of icariin from gelatin/hyaluronic acid composite microspheres. Polym Bull. 2016;73:1055–1066.
   Web of Science ®Google Scholar
• Pan P, Chen J, Fan T, et al. Facile preparation of biphasic-induced magnetic icariin-loaded composite microcapsules by automated in situ click technology. Colloids Surf B Biointerfaces. 2016;140:50–59.
   PubMed Web of Science ®Google Scholar
• Li C, Li Q, Mei Q, et al. Pharmacology effects and pharmacokinetics properties of icariin, the major bioactive component in herba epimedii. Life Sci. 2015;126:57–68.
   PubMed Web of Science ®Google Scholar
• Liu X, Li H, Chen Y, et al. Mixed‐charge nanoparticles for long circulation, low reticuloendothelial system clearance, and high tumor accumulation. Adv Healthcare Mater. 2014;3:1439–1447.
   Web of Science ®Google Scholar
• Heaslet H, Harris M, Fahnoe K, et al. Structural comparison of chromosomal and exogenous dihydrofolate reductase from Staphylococcus aureus in complex with the potent inhibitor trimethoprim. Proteins. 2010;76:706–717.
   Web of Science ®Google Scholar
• Shao CY, Tu JS. Design strategy of antitumor polymer micelles. Pharm Clin Res. 2010;18:286–290.
   Google Scholar
• Gubernator J. Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increased in vivo activity. Expert Opin Drug Deliv. 2011;8:565–580.
   PubMed Web of Science ®Google Scholar
• Kozlowski A, Charles SA, Harris JM. Development of PEGylated interferons for the treatment of chronic hepatitis c. Biodrugs. 2001;15:419–429.
   PubMed Web of Science ®Google Scholar
• Wang R, Xu Y. Development and evaluation of nanoparticles based on mPEG-PLA for controlled delivery of vinpocetine: in vitro and in vivo studies. Artif Cells Nanomed Biotechnol. 2017; 45:157–162.
   PubMed Web of Science ®Google Scholar
• George S, Parameswaran MK, Chakraborty AR, et al. Synthesis and evaluation of the biological activities of some 3-{[5-(6-methyl-4-aryl-2-oxo-1,2,3,4-tetrahydropyrimidin-5-yl)-1,3,4-oxadiazol-2-yl]-imino}-1,3-dihydro-2h-indol-2-one derivatives. Acta Pharm 2008;58:119–129.
   PubMed Web of Science ®Google Scholar
• Yao CX, Shi XL, Xiao L, et al. Increased cardiac distribution of mono-PEGylated radix ophiopogonis polysaccharide in both myocardial infarction and ischemia/reperfusion rats. Int J Nanomed 2015;10:409–418.
   PubMed Web of Science ®Google Scholar
• Eicher T, Hauptmann S, Speicher A. The chemistry of heterocycles: structure, reactions, syntheses, and application. 2nd ed. Weinheim, Germany: Wiley-VCH; 2003; p. 310–380.
   Google Scholar
• Wang J, Sui M, Fan W. Nanoparticles for tumor targeted therapies and their pharmacokinetics. Curr Drug Metab 2010;11:129–141.
   PubMed Web of Science ®Google Scholar
• Maitra A. Calcium phosphate nanoparticles: second-generation nonviral vectors in gene therapy. Expert Rev Mol Diagn. 2005;5:893–905.
   PubMed Web of Science ®Google Scholar
• Zhang H, Zhang C, Ping Q. Research and application of polymeric micelles as drug carriers. Prog Pharm Sci 2002;6:326–329.
   Google Scholar
• Barua S, Mitragotri S. Challenges associated with penetration of nanoparticles across cell and tissue barriers: a review of current status and future prospects. Nano Today. 2014;9:223–243.
   PubMed Web of Science ®Google Scholar
• Maeda H. Tumor-selective delivery of macromolecular drugs via the epr effect: background and future prospects. Bioconjugate Chem. 2010;21:797–802.
   PubMed Web of Science ®Google Scholar
• Yuan Y, Xu S, Zhang CJ, et al. Light-responsive AIE nanoparticles with cytosolic drug release to overcome drug resistance in cancer cells. Polym Chem. 2016;7:3530–3539.
   Web of Science ®Google Scholar
• Qin AJ, Zhang Y, Han N, et al. Preparation and self-assembly of amphiphilic polymer with aggregation-induced emission characteristics. Sci China Chem. 2012;55:772–778.
   Web of Science ®Google Scholar
• Soppimath KS, Liu LH, Seow WY, et al. Multifunctional core/shell nanoparticles self‐assembled from pH‐induced thermosensitive polymers for targeted intracellular anticancer drug delivery. Adv Funct Mater. 2007;17:355–362.
   Web of Science ®Google Scholar
• Lu C, Mikhail AS, Wang X, et al. Hydrogels containing core cross-linked block co-polymer micelles. J Biomater Sci Polym Edition. 2012;23:1069–1090.
   PubMed Web of Science ®Google Scholar
• Rubio J, Alfonso I, Bru M, et al. Gemini amphiphilic pseudopeptides: synthesis and preliminary study of their self-assembling properties. Tetrahedron Lett. 2010;51:5861–5867.
   Web of Science ®Google Scholar
• Jeong YI, Kim DG, Jang MK, et al. Preparation and spectroscopic characterization of methoxypoly(ethylene glycol)-grafted water-soluble chitosan. Carbohydr Res. 2008;343:282–289.
   PubMed Web of Science ®Google Scholar
• Tan SC, Khor E, Tan TK, et al. The degree of deacetylation of chitosan: advocating the first derivative UV-spectrophotometry method of determination. Talanta. 1998;45:713–719.
   PubMed Web of Science ®Google Scholar
• Crawford RM, Jovanović S, Budas GR, et al. Chronic mild hypoxia protects heart-derived h9c2 cells against acute hypoxia/reoxygenation by regulating expression of the sur2a subunit of the atp-sensitive K+ channel. J Biol Chem. 2003;278:31444–31455.
   PubMed Web of Science ®Google Scholar
• Chen TR. In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. Exp Cell Res. 1977;104:255–262.
   PubMed Web of Science ®Google Scholar
• Lerch R, Tamm C, Papageorgiou I, et al. Myocardial fatty acid oxidation during ischaemia and reperfusion. Mol Cell Biochem. 1992;116:103–109.
   PubMed Web of Science ®Google Scholar
• Xu SJ, Yu JJ, Zhan JJ, et al. Pharmacokinetics, tissue distribution, and metabolism study of icariin in rat. Biomed Res Int. 2017;2017:4684962–4684979.
   PubMed Web of Science ®Google Scholar
• Sano E, Tashiro S, Tadakuma H, et al. Type 1 IFN inhibits the growth factor deprived apoptosis of cultured human aortic endothelial cells and protects the cells from chemically induced oxidative cytotoxicity. J Cell Biochem. 2012;113:3823–3834.
   PubMed Web of Science ®Google Scholar
• Kaur G, Narang RK, Rath G, et al. Advances in pulmonary delivery of nanoparticles. Artif Cells Blood Substit Immobil Biotechnol. 2012;40:75–96.
   PubMed Web of Science ®Google Scholar
• Behera SS, Pramanik K, Nayak MK. Recent advancement in the treatment of cardiovascular diseases: conventional therapy to nanotechnology. Curr Pharma Des 2015;21:4479–4497.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Wang F, Li MQ, et al. Self-stabilized hyaluronate nanogel for intracellular co-delivery of doxorubicin and cisplatin to osteosarcoma. Adv Sci. 2018;5:1700821–1700833.
   Web of Science ®Google Scholar
• Chen Y, Wu D, Zhong W, et al. Evaluation of the PEG density in the PEGylated chitosan nanoparticles as a drug carrier for curcumin and mitoxantrone. Nanomaterials. 2018;8:486–500.
   Web of Science ®Google Scholar
• Wu B, Feng JY, Yu LM, et al. Icariin protects cardiomyocytes against ischemia/reperfusion injury by attenuating sirt1-dependent mitochondrial oxidative damage. Br J Pharmacol. 2018;18:14457–14496.
   Google Scholar
• Wu W, Li T, Liu J, et al. Pretreatment before ischemia induction with polymerized human placenta hemoglobin (PolyPHb) attenuates ischemia/reperfusion injury-induced myocardial apoptosis. Artif Cells Blood Substit Immobil Biotechnol. 2011;39:3–6.
   PubMed Web of Science ®Google Scholar
• Cui GL, Xia Q, Zhang YB, et al. Berberine differentially modulates the activities of ERK, p38 MARK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice. J Biol Chem. 2009;284:28420–28429.
   PubMed Web of Science ®Google Scholar
• Ye LY, Hu S, Xu HE, et al. The effect of tetrandrine combined with cisplatin on proliferation and apoptosis of a549/ddp cells and a549 cells. Cancer Cell Int. 2017;17:40–49.
   PubMed Web of Science ®Google Scholar