Comparative evaluation of hesperetin loaded nanoparticles for anticancer activity against C6 glioma cancer cells

References

• Hanif F, Muzaffar K, Perveen K. Glioblastoma multiforme: A review of its epidemiology and pathogenesis through clinical presentation and treatment. Asian Pac J Cancer Prev. 2017;18:3.
   PubMedGoogle Scholar
• Zhang XH, Zhang NN, Meng XB, et al. Hesperetin inhibits the proliferation of cerebrally implanted C6 glioma and involves suppression of HIF-1α/VEGF pathway in rats. Biomed Res. 2017;28:1205-1211.
   Google Scholar
• Bi WL, Beroukhim R. Beating the odds: extreme long-term survival with glioblastoma. Soc Neuro-Oncol. 2014;16(9):1159-1160.
   PubMed Web of Science ®Google Scholar
• Haar CP, Hebbar P, Wallace GC, et al. Drug resistance in glioblastoma: a mini review. Neurochem Res. 2012;37:1192–1200.
   PubMed Web of Science ®Google Scholar
• Murphy J, Spencer D, Cheng Y, et al. Gold Nanoparticles for the Treatment of Malignant Gliomas. THE WORLD SCIENTIFIC ENCYCLOPEDIA OF NANOMEDICINE AND BIOENGINEERING I: Volume 1: Noble Metal Nanoparticles for Biomedical Applications: World Scientific; 2017;151–176.
   Google Scholar
• Prakash O, Kumar A, Kumar P, et al. Anticancer potential of plants and natural products: A. Ajps. 2013;1:104–115.
   Google Scholar
• Galati G, O'brien PJ. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radic Biol Med. 2004;37:287–303.
   PubMed Web of Science ®Google Scholar
• Ravishankar D, Rajora AK, Greco F, et al. Flavonoids as prospective compounds for anti-cancer therapy. Int J Biochem Cell Biol. 2013;45:2821–2831.
   PubMed Web of Science ®Google Scholar
• Galati E, Monforte M, Kirjavainen S, et al. Biological effects of hesperidin, a citrus flavonoid.(Note I): antiinflammatory and analgesic activity. Farmaco. 1994;40:709–712.
   PubMedGoogle Scholar
• Galati E, Trovato A, Kirjavainen S, et al. Biological effects of hesperidin, a Citrus flavonoid.(Note III): antihypertensive and diuretic activity in rat. Farmaco. 1996;51:219–221.
   PubMedGoogle Scholar
• Parhiz H, Roohbakhsh A, Soltani F, et al. Antioxidant and anti‐inflammatory properties of the citrus flavonoids hesperidin and hesperetin: an updated review of their molecular mechanisms and experimental models. Phytother Res. 2015;29:323–331.
   PubMed Web of Science ®Google Scholar
• Sambantham S, Radha M, Paramasivam A, et al. Molecular mechanism underlying hesperetin-induced apoptosis by in silico analysis and in prostate cancer PC-3 cells. Asian Pac J Cancer Prev. 2013;14:4347–4352.
   PubMedGoogle Scholar
• Ye L, Chan FL, Chen S, et al. The citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice. J Nutr Biochem. 2012;23:1230–1237.
   PubMed Web of Science ®Google Scholar
• Alshatwi AA, Ramesh E, Periasamy V, et al. The apoptotic effect of hesperetin on human cervical cancer cells is mediated through cell cycle arrest, death receptor, and mitochondrial pathways. Fundam Clin Pharmacol. 2013;27:581–592.
   PubMed Web of Science ®Google Scholar
• Aranganathan S, Nalini N. Antiproliferative efficacy of hesperetin (citrus flavanoid) in 1, 2‐dimethylhydrazine‐induced colon cancer. Phytother Res. 2013;27:999–1005.
   PubMed Web of Science ®Google Scholar
• Liu L, Chen J. Solubility of hesperetin in various solvents from (288.2 to 323.2) K. J Chem Eng Data. 2008;53:1649–1650.
   Web of Science ®Google Scholar
• Erlund I, Meririnne E, Alfthan G, et al. Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice. J Nutr. 2001;131:235–241.
   PubMed Web of Science ®Google Scholar
• Singh R, Lillard JW. Nanoparticle-based targeted drug delivery. Exp Molecul Pathol. 2009;86:215–223.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Peng Z, Seven ES. Crossing the blood-brain barrier with nanoparticles. J Control Release. 2017;270:290-303.
   Web of Science ®Google Scholar
• Sadat Tabatabaei Mirakabad F, Nejati-Koshki K, Akbarzadeh A, et al. PLGA-based nanoparticles as cancer drug delivery systems. Asian Pac J Cancer Prev. 2014;15:517–535.
   PubMedGoogle Scholar
• Hafezi Ghahestani Z, Alebooye Langroodi F, Mokhtarzadeh A, et al. Evaluation of anti-cancer activity of PLGA nanoparticles containing crocetin. Artif Cells Nanomed Biotechnol. 2017;45:955–960.
   PubMed Web of Science ®Google Scholar
• Ersoz M, Erdemir A, Uzunoglu D, et al., editors. Investigation of anti-cancer activity of hesperetin and hesperetin loaded polymeric nanoparticles on C6 glioma cells. WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: FEBS OPEN BIO; 2018.
   Google Scholar
• Duranoğlu D, Uzunoglu D, Mansuroglu B, et al. Synthesis of hesperetin loaded PLGA nanoparticles by two different experimental design methods and biological evaluation of optimized nanoparticles. Nanotechnol. 2018;29(39).
   PubMed Web of Science ®Google Scholar
• Arasoglu T, Derman S. Assessment of the antigenotoxic activity of poly (d, l-lactic-co-glycolic acid) nanoparticles loaded with caffeic acid phenethyl ester using the AMES/Salmonella microsome assay. J Agri Food Chem. 2018;66(24):6196-6204.
   PubMed Web of Science ®Google Scholar
• Derman S, Akdeste ZM. Particle size and zeta potential investigation of synthetic peptide-protein conjugates/Sentetik peptid-protein konjugatlarının parçacık boyutu ve zeta potensiyel analizi. Turkish J Biochem. 2015;40:282–289.
   Google Scholar
• Arasoglu T, Derman S, Mansuroglu B. Comparative evaluation of antibacterial activity of caffeic acid phenethyl ester and PLGA nanoparticle formulation by different methods. Nanotechnol. 2016;27:025103.
   PubMed Web of Science ®Google Scholar
• Derman S. Caffeic acid phenethyl ester loaded PLGA nanoparticles: effect of various process parameters on reaction yield, encapsulation efficiency, and particle size. J Nanomater. 2015;16:318.
   Google Scholar
• Arasoglu T, Derman S, Mansuroglu B, et al. Synthesis, characterization and antibacterial activity of juglone encapsulated PLGA nanoparticles. J Appl Microbiol. 2017;123:1407–1419.
   PubMed Web of Science ®Google Scholar
• Walker JM. The Bicinchoninic Acid (BCA) assay for Protein Quantitation. The Protein Protocols Handbook. Totowa, NJ: Springer; 2002. p.11–14.
   Google Scholar
• Apel K, Hirt H. Reactive oxygen species: metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol. 2004;55:373–399.
   PubMed Web of Science ®Google Scholar
• Esterbauer H, Cheeseman KH. [42] determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods in enzymology. Vol.186. New York (NY): Elsevier; 1990. p.407–421.
   Google Scholar
• McCord JM, Fridovich I. Superoxide dismutase an enzymic function for erythrocuprein (hemocuprein). J Biol Chem. 1969;244:6049–6055.
   PubMed Web of Science ®Google Scholar
• Boyne AF, Ellman GL. A methodology for analysis of tissue sulfhydryl components. Anal Biochem. 1972;46:639–653.
   PubMed Web of Science ®Google Scholar
• Sousa F, Cruz A, Fonte P, et al. A new paradigm for antiangiogenic therapy through controlled release of bevacizumab from PLGA nanoparticles. Scientific Rep. 2017;7:3736.
   PubMed Web of Science ®Google Scholar
• Fathi M, Varshosaz J, Mohebbi M, et al. Hesperetin-loaded solid lipid nanoparticles and nanostructure lipid carriers for food fortification: preparation, characterization, and modeling. Food Bioprocess Technol. 2013;6:1464–1475.
   Web of Science ®Google Scholar
• Gurushankar K, Gohulkumar M, Prasad NR, et al. Synthesis, characterization and in vitro anti-cancer evaluation of hesperetin-loaded nanoparticles in human oral carcinoma (KB) cells. Adv Nat Sci: Nanosci Nanotechnol. 2013;5:015006.
   Web of Science ®Google Scholar
• Ferreira O, Schro¨der B, Pinho SP. Solubility of hesperetin in mixed solvents. J Chem Eng Data. 2013;58:2616–2621.
   Web of Science ®Google Scholar
• Fathi M, Varshosaz J. Novel hesperetin loaded nanocarriers for food fortification: Production and characterization. J Funct Foods. 2013;5:1382–1391.
   Web of Science ®Google Scholar
• Krishnan G, Subramaniyan J, Subramani PC, et al. Nanochemopreventive effect of polymer functionalized gold nanoparticles containing hesperetin drug inhibited proliferation and induced apoptosis in Hep3B cells. J App Pharm Sci. 2016;6:114–123. Vol.
   Google Scholar
• Evan GI, Vousden KH. Proliferation, cell cycle and apoptosis in cancer. Nature. 2001;411:342.
   PubMed Web of Science ®Google Scholar
• Leifert WR, Abeywardena MY. Grape seed and red wine polyphenol extracts inhibit cellular cholesterol uptake, cell proliferation, and 5-lipoxygenase activity. Nutr Res. 2008;28:842–850.
   PubMed Web of Science ®Google Scholar
• Ramanathan R, Das N, Tan C. Inhibitory effects of 2-hydroxy chalcone and other flavonoids on human cancer cell-proliferation. Int J Oncol. 1993;3:115–119.
   PubMed Web of Science ®Google Scholar
• Yordi EG, Pérez EM, Matos MJ, et al. Antioxidant and pro-oxidant effects of polyphenolic compounds and structure-activity relationship evidence. Nutrition, Well-Being and Health: InTech. 2012.DOI:10.5772/29471
   Google Scholar
• Srivastava S, Somasagara RR, Hegde M, et al. Quercetin, a natural flavonoid interacts with DNA, arrests cell cycle and causes tumor regression by activating mitochondrial pathway of apoptosis. Scientific Rep. 2016;6:24049.
   PubMed Web of Science ®Google Scholar
• Kyrylkova K, Kyryachenko S, Leid M, et al. Detection of Apoptosis by TUNEL Assay. Odontogenesis: Springer; 2012. p. 41–47.
   Google Scholar
• Yallapu MM, Gupta BK, Jaggi M, et al. Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells. J Colloid Interface Sci. 2010;351:19–29.
   PubMed Web of Science ®Google Scholar
• Nair L, Jagadeeshan S, Nair SA, et al. Biological evaluation of 5-fluorouracil nanoparticles for cancer chemotherapy and its dependence on the carrier, PLGA. Int J Nanomed. 2011;6:1685.
   PubMed Web of Science ®Google Scholar
• Acharya A, Das I, Chandhok D, et al. Redox regulation in cancer: a double-edged sword with therapeutic potential. Oxidative Med Cell Long. 2010;3:23–34.
   PubMed Web of Science ®Google Scholar
• Wang F, Gao F, Lan M, et al. Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells. Toxicol in Vitro. 2009;23:808–815.
   PubMed Web of Science ®Google Scholar
• Khoshtabiat L, Mahdavi M, Dehghan G, et al. Oxidative stress-induced apoptosis in chronic myelogenous leukemia k562 cells by an active compound from the dithio-carbamate family. Asian Pac J Cancer Prev. 2016;17:4267–4273.
   PubMedGoogle Scholar
• Pulskamp K, Diabaté S, Krug HF. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol Lett. 2007;168:58–74.
   PubMed Web of Science ®Google Scholar
• Park E-J, Park K. Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro. Toxicol Lett. 2009;184:18–25.
   PubMed Web of Science ®Google Scholar
• Bodduluru LN, Kasala ER, Barua CC, et al. Antiproliferative and antioxidant potential of hesperetin against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice. Chem Biol Interact. 2015;242:345–352.
   PubMed Web of Science ®Google Scholar
• Malhotra A, Nair P, Dhawan D. Modulatory effects of curcumin and resveratrol on lung carcinogenesis in mice. Phytother Res. 2010;24:1271–1277.
   PubMed Web of Science ®Google Scholar
• Rahman K. Studies on free radicals, antioxidants, and co-factors. Clin Interven Aging. 2007;2:219.
   PubMed Web of Science ®Google Scholar