Labour analgesia; Molecular pathway and the role of nanocarriers: a systematic review

References

• Landau R, Ortner CM, Vuilleumier PH. The impact of genetics and other factors on intra-and post-partum pain. Curr Anesthesiol Rep. 2013;3:264–274.
   Google Scholar
• Bair MJ, Robinson RL, Katon W, et al. Depression and pain comorbidity: a literature review. Arch Intern Med. 2003;163:2433–2445.
   PubMed Web of Science ®Google Scholar
• George RB, Allen TK, Habib AS. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: a systematic review and meta-analysis. Anesth Analg. 2013;116:133–144.
   PubMed Web of Science ®Google Scholar
• Capogna G, Camorcia M, Stirparo S, et al. Multidimensional evaluation of pain during early and late labor: a comparison of nulliparous and multiparous women. Int J Obstet Anesth. 2010;19:167–170.
   PubMed Web of Science ®Google Scholar
• Max MB, Stewart WF. The molecular epidemiology of pain: a new discipline for drug discovery. Nat Rev Drug Discov. 2008;7:647.
   PubMed Web of Science ®Google Scholar
• Diatchenko L, Nackley AG, Tchivileva IE, et al. Genetic architecture of human pain perception. TRENDS Genet. 2007;23:605–613.
   PubMed Web of Science ®Google Scholar
• Hiltunen P, Raudaskoski T, Ebeling H, et al. Does pain relief during delivery decrease the risk of postnatal depression? Acta Obstet Gynecol Scand. 2004;83:257–261.
   PubMed Web of Science ®Google Scholar
• Hingson RA, Edwards WB. Continuous caudal analgesia: an analysis of the first ten thousand confinements thus managed with the report of the authors' first thousand cases. JAMA. 1943;123:538–546.
   Google Scholar
• Bucklin BA, Hawkins JL, Anderson JR, et al. Obstetric anesthesia workforce survey twenty-year update. Anesthesiology. 2005;103:645–653.
   PubMed Web of Science ®Google Scholar
• Lucas MJ, Sharma SK, McIntire DD, et al. A randomized trial of labor analgesia in women with pregnancy-induced hypertension. Am J Obstet Gynecol. 2001;185:970–975.
   PubMed Web of Science ®Google Scholar
• Gambling D, Berkowitz J, Farrell TR, et al. A randomized controlled comparison of epidural analgesia and combined spinal-epidural analgesia in a private practice setting: pain scores during first and second stages of labor and at delivery. Anesth Analg. 2013;116:636–643.
   PubMed Web of Science ®Google Scholar
• Salman C, Kayacan N, Ertuğrul F, et al. Combined spinal-epidural anesthesia with epidural volume extension causes a higher level of block than single-shot spinal anesthesia. Braz J Anesthesiol (English Ed). 2013;63:267–272.
   PubMedGoogle Scholar
• Loubert C, Hinova A, Fernando R. Update on modern neuraxial analgesia in labour: a review of the literature of the last 5 years. Anaesthesia. 2011;66:191–212.
   PubMed Web of Science ®Google Scholar
• Meng M-L, Smiley R. Modern neuraxial anesthesia for labor and delivery. F1000Res. 2017;6:1211.
   PubMedGoogle Scholar
• Yam M, Loh Y, Tan C, et al. General pathways of pain sensation and the major neurotransmitters involved in pain regulation. Int J Mol Sci. 2018;19:2164.
   PubMed Web of Science ®Google Scholar
• Green JM, Coupland VA, Kitzinger JV. Expectations, experiences, and psychological outcomes of childbirth: a prospective study of 825 women. Birth. 1990;17:15–24.
   PubMed Web of Science ®Google Scholar
• Labor S, Maguire S. The pain of labour. Rev Pain. 2008;2:15–19.
   PubMedGoogle Scholar
• Brownridge P. The nature and consequences of childbirth pain. Eur J Obstet Gynecol Reprod Biol. 1995;59:S9–S15.
   PubMed Web of Science ®Google Scholar
• Petrie R, Yeh S, Murata Y, et al. The effect of drugs on fetal heart rate variability. Am J Obstet Gynecol. 1978;130:294–299.
   PubMed Web of Science ®Google Scholar
• Mattingly JE, D'Alessio J, Ramanathan J. Effects of obstetric analgesics and anesthetics on the neonate: a review. Paediatr Drugs. 2003;5:615–627.
   PubMedGoogle Scholar
• Ghelardini C, Mannelli LDC, Bianchi E. The pharmacological basis of opioids. Clin Cases Miner Bone Metab. 2015;12:219.
   PubMedGoogle Scholar
• Al-Hasani R, Bruchas MR. Molecular mechanisms of opioid receptor-dependent signaling and behavior. J Am Soc Anesthesiol. 2011;115:1363–1381.
   PubMed Web of Science ®Google Scholar
• Ballantyne JC, Mao J. Opioid therapy for chronic pain. N Engl J Med. 2003;349:1943–1953.
   PubMed Web of Science ®Google Scholar
• Barbani F, Angeli E, De Gaudio AR. Intravenous sedatives and analgesics. In: De Gaudio AR, Romagnoli S, editors. Critical care sedation. Cham: Springer; 2018. p. 69–101.
   Google Scholar
• Prommer E. The role of fentanyl in cancer-related pain. J Palliat Med. 2009;12:947–954.
   PubMed Web of Science ®Google Scholar
• Evron S, Ezri T. Options for systemic labor analgesia. Curr Opin Anaesthesiol. 2007;20:181–185.
   PubMed Web of Science ®Google Scholar
• Hensley JG, Collins MR, Leezer CL. Pain management in obstetrics. Crit Care Nurs Clin North Am. 2017;29:471–485.
   PubMed Web of Science ®Google Scholar
• Kafshdooz L, Pourfathi H, Akbarzadeh A, et al. The role of microRNAs and nanoparticles in ovarian cancer: a review. Artif Cells Nanomed Biotechnol. 2018;46:1–7.
   PubMed Web of Science ®Google Scholar
• Vahabi S, Eatemadi A. Nanoliposome encapsulated anesthetics for local anesthesia application. Biomed Pharmacother. 2017;86:1–7.
   PubMed Web of Science ®Google Scholar
• de Paula E, Cereda C, Tofoli GR, et al. Drug delivery systems for local anesthetics. Ddf. 2010;4:23–34.
   Google Scholar
• Tseng Y-Y, Liu S-J. Nanofibers used for the delivery of analgesics. Nanomedicine (Lond). 2015;10:1785–1800.
   PubMed Web of Science ®Google Scholar
• Tseng Y-Y, Liao J-Y, Chen W-A, et al. Biodegradable poly ([D, L]-lactide-co-glycolide) nanofibers for the sustainable delivery of lidocaine into the epidural space after laminectomy. Nanomedicine. 2014;9:77–87.
   PubMed Web of Science ®Google Scholar
• Csaba N, Garcia-Fuentes M, Alonso MJ. The performance of nanocarriers for transmucosal drug delivery. Expert Opin Drug Deliv. 2006;3:463–478.
   PubMedGoogle Scholar
• Christie JM, Simmonds M, Patt R, et al. Dose-titration, multicenter study of oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain. JCO. 1998;16:3238–3245.
   PubMed Web of Science ®Google Scholar
• Dzambazovska-Trajkovska V, Nojkov J, Kartalov A, et al. Association of single-nucleotide polymorhism C3435T in the ABCB1 gene with opioid sensitivity in treatment of postoperative pain. Prilozi. 2016;37:73–80.
   PubMedGoogle Scholar
• Olesen AE, Sato H, Nielsen LM, et al. The genetic influences on oxycodone response characteristics in human experimental pain. Fundam Clin Pharmacol. 2015;29:417–425.
   PubMed Web of Science ®Google Scholar
• Nielsen LM, Christrup LL, Sato H, et al. Genetic influences of OPRM 1, OPRD 1 and COMT on morphine analgesia in a multi‐modal, multi‐tissue human experimental pain model. Basic Clin Pharmacol Toxicol. 2017;121:6–12.
   PubMed Web of Science ®Google Scholar
• Langford DJ, Paul SM, West CM, et al. Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery. Pain. 2015;156:371–380.
   PubMed Web of Science ®Google Scholar
• Blanco F, Muriel C, Labrador J, et al. Influence of UGT 2B7, CYP 3A4, and OPRM 1 gene polymorphisms on transdermal buprenorphine pain control in patients with critical lower limb ischemia awaiting revascularization. Pain Pract. 2016;16:842–849.
   PubMed Web of Science ®Google Scholar
• Coleman RA, Smith WL, Narumiya S. International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol Rev. 1994;46:205–229.
   PubMed Web of Science ®Google Scholar
• Stockton SD Jr, Devi LA. Functional relevance of μ–δ opioid receptor heteromerization: a role in novel signaling and implications for the treatment of addiction disorders: From a symposium on new concepts in mu-opioid pharmacology. Drug Alcohol Depend. 2012;121:167–172.
   PubMed Web of Science ®Google Scholar
• Flores CM, Mogil JS. The pharmacogenetics of analgesia: toward a genetically-based approach to pain management. Pharmacogenomics. 2001;2:177–194.
   PubMed Web of Science ®Google Scholar
• Hung C-C, Chiou M-H, Huang B-H, et al. Impact of genetic polymorphisms in ABCB1, CYP2B6, OPRM1, ANKK1 and DRD2 genes on methadone therapy in Han Chinese patients. Pharmacogenomics. 2011;12:1525–1533.
   PubMed Web of Science ®Google Scholar
• Deb I, Chakraborty J, Gangopadhyay PK, et al. Single‐nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu‐opioid receptor and may contribute to the genetic risk for addiction. J Neurochem. 2010;112:486–496.
   PubMed Web of Science ®Google Scholar
• Baber M, Bapat P, Nichol G, et al. The pharmacogenetics of opioid therapy in the management of postpartum pain: a systematic review. Pharmacogenomics. 2016;17:75–93.
   PubMed Web of Science ®Google Scholar
• Landau R. Genetic contributions to labor pain and progress. Clin Perinatol. 2013;40:575–587.
   PubMed Web of Science ®Google Scholar
• Shi J, Hui L, Xu Y, et al. Sequence variations in the mu‐opioid receptor gene (OPRM1) associated with human addiction to heroin. Hum Mutat. 2002;19:459–460.
   PubMed Web of Science ®Google Scholar
• Hawkins JL. Epidural analgesia for labor and delivery. N Engl J Med. 2010;362:1503–1510.
   PubMed Web of Science ®Google Scholar
• Kleinjan M, Poelen EA, Engels RC, et al. Dual growth of adolescent smoking and drinking: evidence for an interaction between the mu‐opioid receptor (OPRM1) A118G polymorphism and sex. Addict Biol. 2013;18:1003–1012.
   PubMed Web of Science ®Google Scholar
• Song Z, Du B, Wang K, et al. Effects of OPRM1 A118G polymorphism on epidural analgesia with fentanyl during labor: a meta-analysis. Genet Test Mol Biomarkers. 2013;17:743–749.
   PubMed Web of Science ®Google Scholar
• Zhang S, Li S, Tan X. Human µ-opioid receptor A118G polymorphism affects epidural patient-controlled analgesia with fentanyl. Nan Fang yi ke da Xue Xue Bao = J Southern Med Univ. 2013;33:309–311.
   PubMedGoogle Scholar
• Bond C, LaForge KS, Tian M, et al. Single-nucleotide polymorphism in the human mu opioid receptor gene alters β-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci. 1998;95:9608–9613.
   PubMed Web of Science ®Google Scholar
• Rhodin A, Grönbladh A, Ginya H, et al. Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects. Mol Brain. 2013;6:8.
   PubMed Web of Science ®Google Scholar
• Pettersson FD, Grönbladh A, Nyberg F, et al. The A118G single-nucleotide polymorphism of human µ-opioid receptor gene and use of labor analgesia. Reprod Sci. 2012;19:962–967.
   PubMed Web of Science ®Google Scholar
• Landau R, Kern C, Columb MO, et al. Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women. Pain. 2008;139:5–14.
   PubMed Web of Science ®Google Scholar
• Crowley JJ, Oslin DW, Patkar AA, et al. A genetic association study of the mu opioid receptor and severe opioid dependence. Psychiatr Genet. 2003;13:169–173.
   PubMed Web of Science ®Google Scholar
• Wong C, McCarthy R, Blouin J, et al. Observational study of the effect of μ-opioid receptor genetic polymorphism on intrathecal opioid labor analgesia and post-cesarean delivery analgesia. Int J Obstet Anesth. 2010;19:246–253.
   PubMed Web of Science ®Google Scholar
• Camorcia M, Capogna G, Stirparo S, et al. Effect of μ-opioid receptor A118G polymorphism on the ED50 of epidural sufentanil for labor analgesia. Int J Obstetr Anesth. 2012;21:40–44.
   PubMed Web of Science ®Google Scholar
• Dabo F, Grönbladh A, Nyberg F, et al. Different SNP combinations in the GCH1 gene and use of labor analgesia. Mol Pain. 2010;6:41.
   PubMed Web of Science ®Google Scholar
• Tegeder I, Costigan M, Griffin RS, et al. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med. 2006;12:1269.
   PubMed Web of Science ®Google Scholar
• Kaneko YS, Ikemoto K, Mori K, et al. Expression of GTP cyclohydrolase I in murine locus ceruleus is enhanced by peripheral administration of lipopolysaccharide. Brain Res. 2001;890:203–210.
   PubMed Web of Science ®Google Scholar
• Shimizu S, Shiota K, Yamamoto S, et al. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells. Free Radic Biol Med. 2003;34:1343–1352.
   PubMed Web of Science ®Google Scholar
• Lee S-G, Joo Y, Kim B, et al. Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans. Hum Genet. 2005;116:319–328.
   PubMed Web of Science ®Google Scholar
• Lachman HM, Papolos DF, Saito T, et al. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics. 1996;6:243–250.
   PubMedGoogle Scholar
• Boecker-Schlier R, Holz NE, Buchmann AF, et al. Interaction between COMT Val158Met polymorphism and childhood adversity affects reward processing in adulthood. Neuroimage. 2016;132:556–570.
   PubMed Web of Science ®Google Scholar
• Lundstr K, Salminen M, Jalanko A, et al. Cloning and characterization of human placental catechol–methyltransferase cDNA. DNA Cell Biol. 1991;10:181–189.
   PubMed Web of Science ®Google Scholar
• Zubieta J-K, Heitzeg MM, Smith YR, et al. COMT val158met genotype affects µ-opioid neurotransmitter responses to a pain stressor. Science. 2003;299:1240–1243.
   PubMed Web of Science ®Google Scholar
• Pak Y, Pham N, Rotin D. Direct binding of the β1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation. Mol Cell Biol. 2002;22:7942–7952.
   PubMed Web of Science ®Google Scholar
• Moriyama A, Nishizawa D, Kasai S, et al. Association between genetic polymorphisms of the β1-adrenergic receptor and sensitivity to pain and fentanyl in patients undergoing painful cosmetic surgery. J Pharmacol Sci. 2013;121:48–57.
   PubMed Web of Science ®Google Scholar
• Feng S, Li N, Xu S, et al. Association of ADRB1 gene polymorphisms with pain sensitivity in a Chinese population. Int J Clin Exp Med. 2015;8:11514.
   PubMed Web of Science ®Google Scholar
• Wei W, Tian Y, Zhao C, et al. Correlation of ADRB1 rs1801253 polymorphism with analgesic effect of fentanyl after cancer surgeries. Med Sci Monit. 2015;21:4000.
   PubMed Web of Science ®Google Scholar