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Research Article

Emodin weakens liver inflammatory injury triggered by lipopolysaccharide through elevating microRNA-145 in vitro and in vivo

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Pages 1877-1887 | Received 01 Feb 2019, Accepted 19 Apr 2019, Published online: 11 May 2019

References

  • Rizzetto M. Chronic hepatitis D; at a standstill? Dig Dis. 2016;34:303–307.
  • Kajiya M, Sato K, Silva MJ, et al. Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis. Biochem Biophys Res Commun. 2009;386:316–321.
  • Morgnanesi D, Heinrichs EJ, Mele AR, et al. A computational chemistry perspective on the current status and future direction of hepatitis B antiviral drug discovery. Antiviral Res. 2015;123:204–215.
  • Czaja AJ. Diagnosis and management of autoimmune hepatitis: current status and future directions. Gut Liver. 2016;10:177–203.
  • Mathurin P, Lucey MR. Management of alcoholic hepatitis. J Hepatol. 2012;56:S39–S45.
  • Gurung RB, Purbe B, Gyawali P, et al. The ratio of aspartate aminotransferase to alanine aminotransferase (AST/ALT): the correlation of value with underlying severity of alcoholic liver disease. Kathmandu Univ Med J. 2015;11:233–236.
  • Wu SJ, Lin YX, Ye H, et al. Prognostic value of alkaline phosphatase, gamma-glutamyl transpeptidase and lactate dehydrogenase in hepatocellular carcinoma patients treated with liver resection. Int J Surg (London, England). 2016;36:143–151.
  • Chen Z, Liu H, Lei S, et al. LY294002 prevents lipopolysaccharideinduced hepatitis in a murine model by suppressing IkappaB phosphorylation. Mol Med Rep. 2016;13:811–816.
  • Chang MH, Chang SC, Chan WH. Injurious effects of emodin on maturation of mouse oocytes, fertilization and fetal development via apoptosis. IJMS. 2012;13:13911–13925.
  • Ha MK, Song YH, Jeong SJ, et al. Emodin inhibits proinflammatory responses and inactivates histone deacetylase 1 in hypoxic rheumatoid synoviocytes. Biol Pharm Bull. 2011;34:1432–1437.
  • Alisi A, Pastore A, Ceccarelli S, et al. Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats. IJMS. 2012;13:2276–2289.
  • Lee W, Ku SK, Kim TH, et al. Emodin-6-O-beta-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo. Food Chem Toxicol. 2013;52:97–104.
  • Song LH, Hu MM, Liu D, et al. Thermal cracking of Enteromorpha prolifera with solvents to bio-oil. Energy Convers Manage. 2014;77:7–12.
  • Liu D, Wu J, Liu M, et al. Downregulation of miRNA-30c and miR-203a is associated with hepatitis C virus core protein-induced epithelial-mesenchymal transition in normal hepatocytes and hepatocellular carcinoma cells. Biochem Biophys Res Commun. 2015;464:1215–1221.
  • Bandopadhyay M, Banerjee A, Sarkar N, et al. Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytes. BMC Cancer. 2014;14:721.
  • Gao F, Sun X, Wang L, et al. Downregulation of microRNA-145 caused by hepatitis B virus X protein promotes expression of CUL5 and contributes to pathogenesis of hepatitis B virus-associated hepatocellular carcinoma. Cell Physiol Biochem. 2015;37:1547–1559.
  • Ulmer AJ, Flad H, Rietschel T, et al. Induction of proliferation and cytokine production in human T lymphocytes by lipopolysaccharide (LPS). Toxicology. 2000;152:37–45.
  • Huang X, Liu Y, Lu Y, et al. Anti-inflammatory effects of eugenol on lipopolysaccharide-induced inflammatory reaction in acute lung injury via regulating inflammation and redox status. Int Immunopharmacol. 2015;26:265–271.
  • Yao J, Pan D, Zhao Y, et al. Wogonin prevents lipopolysaccharide-induced acute lung injury and inflammation in mice via peroxisome proliferator-activated receptor gamma-mediated attenuation of the nuclear factor-kappaB pathway. Immunology. 2014;143:241–257.
  • Perea L, Coll M, Sanjurjo L, et al. Pentraxin-3 modulates lipopolysaccharide-induced inflammatory response and attenuates liver injury. 2017;66(3):953–968.
  • Zhang J, Yang S, Chen F, et al. Ginkgetin aglycone ameliorates LPS-induced acute kidney injury by activating SIRT1 via inhibiting the NF-kappaB signaling pathway. Cell Biosci. 2017;7:44.
  • Fan X, Zhang Y, Dong H, et al. Trilobatin attenuates the LPS-mediated inflammatory response by suppressing the NF-kappaB signaling pathway. Food Chem. 2015;166:609–615.
  • Matsui Y, Kikuchi T, Inoue T, et al. Carapanolides J-L from the seeds of Carapa guianensis (Andiroba) and their effects on LPS-activated NO production. Molecules. 2014;19:17130–17140.
  • Ish-Shalom S, Lichter A. Analysis of fungal gene expression by Real Time quantitative PCR. Methods Mol Biol (Clifton, NJ). 2010;638:103–114.
  • Li R, Yin F, Guo YY, et al. Knockdown of ANRIL aggravates H2O2-induced injury in PC-12 cells by targeting microRNA-125a. Biomed Pharmacother. 2017;92:952–961.
  • Tsai T-H, Tam K, Chen S-F, et al. Deletion of caveolin-1 attenuates LPS/GalN-induced acute liver injury in mice. J Cell Mol Med. 2018;22:5573–5582.
  • Xue J, Chen F, Wang J, et al. Emodin protects against concanavalin A-induced hepatitis in mice through inhibiting activation of the p38 MAPK-NF-kappaB signaling pathway. Cell Physiol Biochem. 2015;35:1557–1570.
  • Kyrylkova K, Kyryachenko S, Leid M, et al. Detection of apoptosis by TUNEL assay. Methods Mol Biol. 2012;887:41–47.
  • Sengupta T, Vinayagam J, Singh R, et al. Plant-derived natural products for Parkinson's disease therapy. Adv Neurobiol. 2016;12:415–496.
  • Fridlender M, Kapulnik Y, Koltai H. Plant derived substances with anti-cancer activity: from folklore to practice. Front Plant Sci. 2015;6:799.
  • Dai G, Sun B, Wu L, et al. Comparative pharmacokinetics of three alkaloids in normal and acute hepatitis rats after oral administration of Yanhuanglian total alkaloids extract. Biomed Chromatogr. 2018;32:e4329.
  • Kasprzak A, Seidel J, Spachacz R, et al. Intracellular expression of pro-inflammatory cytokines (IL-1alpha, TNF-alpha, and IL-6) in chronic hepatitis C. Roczniki Akademii Medycznej w Bialymstoku (1995). 2004;49:207–209.
  • Leeman JR, Gilmore TD. Alternative splicing in the NF-kappaB signaling pathway. Gene. 2008;423:97–107.
  • Liu Q, Qian Y, Chen F, et al. EGCG attenuates pro-inflammatory cytokines and chemokines production in LPS-stimulated L02 hepatocyte. Acta Biochim Biophys Sinica. 2014;46:31–39.
  • Fabian MR, Sonenberg N, Filipowicz W. Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem. 2010;79:351–379.
  • Sheth S, Jajoo S, Kaur T, et al. Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway. PloS One. 2012;7:e51655.
  • Zheng J, Wu C, Lin Z, et al. Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation–a novel mechanism suppressing liver fibrosis. FEBS J. 2014;281:88–103.
  • Chan LS, Yue PY, Wong YY, et al. MicroRNA-15b contributes to ginsenoside-Rg1-induced angiogenesis through increased expression of VEGFR-2. Biochem Pharmacol. 2013;86:392–400.
  • Su J, Richter K, Zhang C, et al. Differential regulation of interleukin-1 receptor associated kinase 1 (IRAK1) splice variants. Mol Immunol. 2007;44:900–905.
  • Maitra U, Singh N, Gan L, et al. IRAK-1 contributes to lipopolysaccharide-induced reactive oxygen species generation in macrophages by inducing NOX-1 transcription and Rac1 activation and suppressing the expression of antioxidative enzymes. J Biol Chem. 2009;284:35403–35411.
  • Joh EH, Jeong JJ, Kim DH. Kalopanaxsaponin B inhibits LPS-induced inflammation by inhibiting IRAK1 Kinase. Cell Immunol. 2012;279:103–108.
  • Li X, Ji Z, Li S, et al. miR-146a-5p antagonized AGEs- and P.g-LPS-induced ABCA1 and ABCG1 dysregulation in macrophages via IRAK-1 downregulation. Inflammation 2015;38:1761–1768.