ASF1A regulates H4^Y72 phosphorylation and promotes autophagy in colon cancer cells via a kinase activity

References

• Tamas K, Walenkamp AM, de Vries EG, et al. Rectal and colon cancer: not just a different anatomic site. Cancer Treatment Rev. 2015;41:671–679.
   PubMed Web of Science ®Google Scholar
• Landreau P, Drouillard A, Launoy G, et al. Incidence and survival in late liver metastases of colorectal cancer. J Gastroenterol Hepatol. 2015;30:82–85.
   PubMed Web of Science ®Google Scholar
• Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol. 2010;28:1057–1068.
   PubMed Web of Science ®Google Scholar
• Balakrishnan L, Milavetz B. Epigenetic regulation of viral biological processes. Viruses. 2017;9:346.
   PubMed Web of Science ®Google Scholar
• Audia JE, Campbell RM. Histone modifications and cancer. Cold Spring Harb Perspect Biol. 2016;8:a019521.
   PubMed Web of Science ®Google Scholar
• Tessarz P, Kouzarides T. Histone core modifications regulating nucleosome structure and dynamics. Nat Rev Mol Cell Biol. 2014;15:703–708.
   PubMed Web of Science ®Google Scholar
• Lennartsson A, Ekwall K. Histone modification patterns and epigenetic codes. Biochim Biophys Acta. 2009;1790:863–868.
   PubMed Web of Science ®Google Scholar
• Hattori N, Ushijima T. Compendium of aberrant DNA methylation and histone modifications in cancer. Biochem Biophys Res Commun. 2014;455:3–9.
   PubMed Web of Science ®Google Scholar
• Dryhurst D, Ausio J. Histone H2A.Z deregulation in prostate cancer. Cause or effect? Cancer Metastasis Rev. 2014;33:429–439.
   PubMed Web of Science ®Google Scholar
• Yang WY, Gu JL, Zhen TM. Recent advances of histone modification in gastric cancer. J Can Res Ther. 2014;10:240–245.
   PubMed Web of Science ®Google Scholar
• Deb M, Sengupta D, Kar S, et al. Epigenetic drift towards histone modifications regulates CAV1 gene expression in colon cancer. Gene 2016;581:75–84.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Munoz E, Arboleda-Estudillo Y, Otu HH, et al. Cell reprogramming. Histone chaperone ASF1A is required for maintenance of pluripotency and cellular reprogramming. Science (New York, NY). 2014;345:822–825.
   Google Scholar
• Gao Y, Gan H, Lou Z, et al. Asf1a resolves bivalent chromatin domains for the induction of lineage-specific genes during mouse embryonic stem cell differentiation. Proc Natl Acad Sci USA. 2018;115:E6162–e6171.
   PubMed Web of Science ®Google Scholar
• Henrique R. ASF1A in gastric and colorectal cancer: on the hinge between genetics and epigenetics? EBioMedicine. 2017; 21:45–46.
   PubMed Web of Science ®Google Scholar
• Wang C, Chang JF, Yan H, et al. A conserved RAD6-MDM2 ubiquitin ligase machinery targets histone chaperone ASF1A in tumorigenesis. Oncotarget. 2015;6:29599–29613.
   PubMedGoogle Scholar
• Yang S, Liu L, Cao C, et al. USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization. Nature Commun. 2018;9:1285.
   PubMed Web of Science ®Google Scholar
• Wen J, Zhao Y, Guo L. Orexin A induces autophagy in HCT-116 human colon cancer cells through the ERK signaling pathway. Int J Mol Med. 2016;37:126–132.
   PubMed Web of Science ®Google Scholar
• Asare EA, Compton CC, Hanna NN, et al. The impact of stage, grade, and mucinous histology on the efficacy of systemic chemotherapy in adenocarcinomas of the appendix: analysis of the National Cancer Data Base. Cancer. 2016; 122:213–221.
   PubMed Web of Science ®Google Scholar
• Varghese F, Bukhari AB, Malhotra R, et al. IHC Profiler: an open source plugin for the quantitative evaluation and automated scoring of immunohistochemistry images of human tissue samples. PloS One. 2014;9:e96801.
   PubMed Web of Science ®Google Scholar
• Jaskelioff M, Gavin IM, Peterson CL, et al. SWI-SNF-mediated nucleosome remodeling: role of histone octamer mobility in the persistence of the remodeled state. Mol Cell Biol. 2000;20:3058–3068.
   PubMed Web of Science ®Google Scholar
• Yang JH, Song TY, Jo C, et al. Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Exp Mol Med. 2016;48:e252.
   PubMed Web of Science ®Google Scholar
• Liang X, Yuan X, Yu J, et al. Histone chaperone ASF1A predicts poor outcomes for patients with gastrointestinal cancer and drives cancer progression by stimulating transcription of beta-catenin target genes. EBioMedicine. 2017;21:104–116.
   PubMed Web of Science ®Google Scholar
• Lu W, Ke H, Qianshan D, et al. Apatinib has anti-tumor effects and induces autophagy in colon cancer cells. Iran J Basic Med Sci. 2017;20:990–995.
   PubMed Web of Science ®Google Scholar
• Drake KR, Kang M, Kenworthy AK. Nucleocytoplasmic distribution and dynamics of the autophagosome marker EGFP-LC3. PloS One. 2010;5:e9806.
   PubMed Web of Science ®Google Scholar
• Yoshii SR, Mizushima N. Monitoring and measuring autophagy. Int J Mol Sci. 2017;18: E1865.
   PubMed Web of Science ®Google Scholar
• Zeng M, Zhu L, Li L, et al. miR-378 suppresses the proliferation, migration and invasion of colon cancer cells by inhibiting SDAD1. Cell Mol Biol Lett. 2017;22:12.
   PubMed Web of Science ®Google Scholar
• Ahluwalia A, Jones MK, Matysiak-Budnik T, et al. VEGF and colon cancer growth beyond angiogenesis: does VEGF directly mediate colon cancer growth via a non-angiogenic mechanism? Cpd. 2014;20:1041–1044.
   Web of Science ®Google Scholar
• Okugawa Y, Grady WM, Goel A. Epigenetic alterations in colorectal cancer: emerging biomarkers. Gastroenterology. 2015; 149:1204–1225.e12.
   PubMed Web of Science ®Google Scholar
• Dhar S, Gursoy-Yuzugullu O, Parasuram R, et al. The tale of a tail: histone H4 acetylation and the repair of DNA breaks. Philos Trans R Soc Lond B Biol Sci. 2017;372:20160284.
   PubMed Web of Science ®Google Scholar
• Chou RH, Wang YN, Hsieh YH, et al. EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4. Dev Cell. 2014;30:224–237.
   PubMed Web of Science ®Google Scholar
• Yoon J, Kim SJ, An S, et al. integrative structural investigation on the architecture of human Importin4_Histone H3/H4_Asf1a complex and its histone H3 tail binding. J Mol Biol. 2018;430:822–841.
   PubMed Web of Science ®Google Scholar
• Levy JMM, Towers CG, Thorburn A. Targeting autophagy in cancer. Nat Rev Cancer. 2017;17:528–542.
   PubMed Web of Science ®Google Scholar
• Lin WM, Li ZG. Blockage of cisplatin-induced autophagy sensitizes cervical cancer cells to cisplatin. Genet Mol Res. 2015;14:16905–16912.
   PubMed Web of Science ®Google Scholar
• Muilenburg D, Parsons C, Coates J, et al. Role of autophagy in apoptotic regulation by Akt in pancreatic cancer. Anticancer Res. 2014;34:631–637.
   PubMed Web of Science ®Google Scholar
• Hanada T, Noda NN, Satomi Y, et al. The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem. 2007; 282:37298–37302.
   PubMed Web of Science ®Google Scholar
• Fullgrabe J, Heldring N, Hermanson O, et al. Cracking the survival code: autophagy-related histone modifications. Autophagy. 2014;10:556–561.
   PubMed Web of Science ®Google Scholar