Angelica polysaccharide moderates hypoxia-evoked apoptosis and autophagy in rat neural stem cells by downregulation of BNIP3

References

• Miguel PM, Schuch CP, Rojas JJ, et al. Neonatal hypoxia-ischemia induces attention-deficit hyperactivity disorder-like behavior in rats. Behav Neurosci. 2015;129:309–320.
   PubMed Web of Science ®Google Scholar
• Vasquez-Vivar J, Shi Z, Luo K, et al. Tetrahydrobiopterin in antenatal brain hypoxia-ischemia-induced motor impairments and cerebral palsy. Redox Biol. 2017;13:594–599.
   PubMed Web of Science ®Google Scholar
• Chicha L, Smith T, Guzman R. Stem cells for brain repair in neonatal hypoxia-ischemia. Childs Nerv Syst 2014;30:37–46.
   PubMed Web of Science ®Google Scholar
• Sun K, Fan J, Han J. Ameliorating effects of traditional Chinese medicine preparation, Chinese materia medica and active compounds on ischemia/reperfusion-induced cerebral microcirculatory disturbances and neuron damage. Acta Pharm Sinica B. 2015;5:8–24.
   PubMed Web of Science ®Google Scholar
• Bian H, Shan H, Chen T. Resveratrol ameliorates hypoxia/ischemia-induced brain injury in the neonatal rat via the miR-96/Bax axis. Childs Nerv Syst. 2017;33:1937–1945.
   PubMed Web of Science ®Google Scholar
• Xie Y, Zhang H, Zhang Y, et al. Chinese angelica polysaccharide (CAP) alleviates LPS-induced inflammation and apoptosis by down-regulating COX-1 in PC12 cells. Cell Physiol Biochem. 2018;49:1380–1388.
   PubMedGoogle Scholar
• Li R, Yin F, Guo Y, et al. Angelica polysaccharide protects PC-12 cells from lipopolysaccharide-induced injury via down-regulating microRNA-223. Biomed Pharmacother. 2018;108:1320–1327.
   PubMed Web of Science ®Google Scholar
• Pan H, Zhu L. Angelica sinensis polysaccharide protects rat cardiomyocytes H9c2 from hypoxia-induced injury by down-regulation of microRNA-22. Biomed Pharmacother. 2018;106:225–231.
   PubMed Web of Science ®Google Scholar
• Lei T, Li H, Fang Z, et al. Polysaccharides from Angelica sinensis alleviate neuronal cell injury caused by oxidative stress. Neural Regen Res. 2014;9:260–267.
   PubMed Web of Science ®Google Scholar
• Walls KC, Ghosh AP, Ballestas ME, et al. bcl-2/Adenovirus E1B 19-kd interacting protein 3 (BNIP3) regulates hypoxia-induced neural precursor cell death. J Neuropathol Exp Neurol. 2009;68:1326–1338.
   PubMed Web of Science ®Google Scholar
• Yang J, Shao X, Jiang J, et al. Angelica sinensis polysaccharide inhibits proliferation, migration, and invasion by downregulating microRNA-675 in human neuroblastoma cell line SH-SY5Y. Cell Biol Int. 2018;42:867–876.
   PubMed Web of Science ®Google Scholar
• Niu X, Zhang J, Ling C, et al. Polysaccharide from Angelica sinensis protects H9c2 cells against oxidative injury and endoplasmic reticulum stress by activating the ATF6 pathway. J Int Med Res. 2018;46:1717–1733.
   PubMed Web of Science ®Google Scholar
• Carloni S, Buonocore G, Balduini W. Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury. Neurobiol Dis. 2008;32:329–339.
   PubMed Web of Science ®Google Scholar
• Maejima Y, Isobe M, Sadoshima J. Regulation of autophagy by Beclin 1 in the heart. J Mol Cell Cardiol. 2016;95:19–25.
   PubMed Web of Science ®Google Scholar
• Liu H, Dai C, Fan Y, et al. From autophagy to mitophagy: the roles of P62 in neurodegenerative diseases. J Bioenerg Biomembr. 2017;49:413–422.
   PubMed Web of Science ®Google Scholar
• Lechpammer M, Wintermark P, Merry KM, et al. Dysregulation of FMRP/mTOR signaling cascade in hypoxic-ischemic injury of premature human brain. J Child Neurol. 2016;31:426–432.
   PubMed Web of Science ®Google Scholar
• Lechpammer M, Tran YP, Wintermark P, et al. Upregulation of cystathionine beta-synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury. Brain Pathol. 2017;27:449–458.
   PubMed Web of Science ®Google Scholar
• Braccioli L, Vervoort SJ, Adolfs Y, et al. FOXP1 promotes embryonic neural stem cell differentiation by repressing Jagged1 expression. Stem Cell Reports. 2017;9:1530–1545.
   PubMed Web of Science ®Google Scholar
• Ji P, Wei Y, Xue W, et al. Characterization and antioxidative activities of polysaccharide in Chinese angelica and its processed products. Int J Biol Macromol. 2014;67:195–200.
   PubMed Web of Science ®Google Scholar
• Wang K, Song Z, Wang H, et al. Angelica sinensis polysaccharide attenuates concanavalin A-induced liver injury in mice. Int Immunopharmacol. 2016;31:140–148.
   PubMed Web of Science ®Google Scholar
• Xia JY, Fan YL, Jia DY, et al. [Protective effect of Angelica sinensis polysaccharide against liver injury induced by D-galactose in aging mice and its mechanisms]. Zhonghua Gan Zang Bing za Zhi 2016;24:214–219.
   PubMedGoogle Scholar
• Zhang S, He B, Ge J, et al. Extraction, chemical analysis of Angelica sinensis polysaccharides and antioxidant activity of the polysaccharides in ischemia-reperfusion rats. Int J Biol Macromol. 2010;47:546–550.
   PubMed Web of Science ®Google Scholar
• Zhuang C, Xu NW, Gao GM, et al. Polysaccharide from Angelica sinensis protects chondrocytes from H2O2-induced apoptosis through its antioxidant effects in vitro. Int J Biol Macromol. 2016;87:322–328.
   PubMed Web of Science ®Google Scholar
• Xiao H, Xiong L, Song X, et al. Angelica sinensis polysaccharides ameliorate stress-induced premature senescence of hematopoietic cell via protecting bone marrow stromal cells from oxidative injuries caused by 5-fluorouracil. Int J Mol Sci. 2017;18:E2265.
   PubMed Web of Science ®Google Scholar
• Cao P, Sun J, Sullivan MA, et al. Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury and cell death by suppressing oxidative stress and hepatic apoptosis in vivo and in vitro. Int J Biol Macromol. 2018;111:1133–1139.
   PubMed Web of Science ®Google Scholar
• Li Z, Yuan Y, Meng Y, et al. Autophagy upregulation ameliorates cell injury in Sequestosome 1 knockout podocytes in vitro. Biochem Biophys Res Commun. 2017;490:98–103.
   PubMed Web of Science ®Google Scholar
• Lamark T, Svenning S, Johansen T. Regulation of selective autophagy: the p62/SQSTM1 paradigm. Essays Biochem. 2017;61:609–624.
   PubMed Web of Science ®Google Scholar
• Bai X, Liu S, Yuan L, et al. Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice. Brain Res. 2016;1646:410–417.
   PubMed Web of Science ®Google Scholar
• Zeng Q, Fu Q, Wang X, et al. Protective effects of sonic hedgehog against ischemia/reperfusion injury in mouse skeletal muscle via AKT/mTOR/p70S6K signaling. Cell Physiol Biochem. 2017;43:1813–1828.
   PubMedGoogle Scholar
• Zhang J, Zhang D, Yan T, et al. BNIP3 promotes the motility and migration of keratinocyte under hypoxia. Exp Dermatol. 2017;26:416–422.
   PubMed Web of Science ®Google Scholar
• Ishihara M, Urushido M, Hamada K, et al. Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury. Am J Physiol Renal Physiol. 2013;305:F495–F509.
   PubMed Web of Science ®Google Scholar
• Luan Y, Zhang X, Zhang Y, et al. MicroRNA-210 protects PC-12 cells against hypoxia-induced injury by targeting BNIP3. Front Cell Neurosci. 2017;11:285.
   PubMed Web of Science ®Google Scholar
• Du Y, Li J, Xu T, et al. MicroRNA-145 induces apoptosis of glioma cells by targeting BNIP3 and Notch signaling. Oncotarget 2017;8:61510–61527.
   PubMedGoogle Scholar