LINC00305 represses miR-124 expression to trigger inflammatory insults in the presence of lipopolysaccharide

References

• Deshpande BR, Katz JN, Solomon DH, et al. Number of persons with symptomatic knee osteoarthritis in the US: impact of race and ethnicity, age, sex, and obesity. Arthritis Care & Res. 2016;68:1743–1750.
   PubMed Web of Science ®Google Scholar
• Thomas AC, Hubbard-Turner T, Wikstrom EA, et al. Epidemiology of posttraumatic osteoarthritis. J Athl Train. 2017;52:491–496.
   PubMed Web of Science ®Google Scholar
• Niu J, Clancy M, Aliabadi P, et al. Metabolic syndrome, its components, and knee osteoarthritis: the Framingham Osteoarthritis Study. Arthritis & Rheumatol. 2017;69:1194–1203.
   PubMed Web of Science ®Google Scholar
• Silverwood V, Blagojevic-Bucknall M, Jinks C, et al. Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis. Osteoarthr Cartil. 2015;23:507–515.
   PubMed Web of Science ®Google Scholar
• Robinson WH, Lepus CM, Wang Q, et al. Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis. Nat Rev Rheumatol. 2016;12:580–592.
   PubMed Web of Science ®Google Scholar
• Mathiessen A, Conaghan PG. Synovitis in osteoarthritis: current understanding with therapeutic implications. Arthr Res Ther. 2017;19:18.
   PubMed Web of Science ®Google Scholar
• Wang T, He C. Pro-inflammatory cytokines: the link between obesity and osteoarthritis. Cytokine & Growth Fact Rev. 2018;44:38–50.
   PubMed Web of Science ®Google Scholar
• Marques-Rocha JL, Samblas M, Milagro FI, et al. Noncoding RNAs, cytokines, and inflammation-related diseases. FASEB J: Offic Publ Feder Am Soc Exper Biol. 2015;29:3595–3611.
   PubMed Web of Science ®Google Scholar
• Chinzei N, Rai MF, Hashimoto S, et al. Evidence for genetic contribution to variation in posttraumatic osteoarthritis in mice. Arthr Rheumatol. 2019;71:370–381.
   PubMed Web of Science ®Google Scholar
• Barter MJ, Young DA. Epigenetic mechanisms and non-coding RNAs in osteoarthritis. Curr Rheumatol Rep. 2013;15:353.
   PubMed Web of Science ®Google Scholar
• Li Y, Li S, Luo Y, et al. LncRNA PVT1 regulates chondrocyte apoptosis in osteoarthritis by acting as a sponge for miR-488-3p. DNA and Cell Biol. 2017;36:571–580.
   PubMed Web of Science ®Google Scholar
• Zhang G, Wu Y, Xu D, et al. Long noncoding RNA UFC1 promotes proliferation of chondrocyte in osteoarthritis by acting as a sponge for miR-34a. DNA and Cell Biol. 2016;35:691–695.
   PubMed Web of Science ®Google Scholar
• Hu G, Zhao X, Wang C, et al. MicroRNA-145 attenuates TNF-alpha-driven cartilage matrix degradation in osteoarthritis via direct suppression of MKK4. Cell Death Dis. 2017;8:e3140.
   PubMed Web of Science ®Google Scholar
• Li ZC, Han N, Li X, et al. Decreased expression of microRNA-130a correlates with TNF-alpha in the development of osteoarthritis. Int J Clin Exper Pathol. 2015;8:2555–2564.
   PubMed Web of Science ®Google Scholar
• Yoon JH, Abdelmohsen K, Gorospe M. Functional interactions among microRNAs and long noncoding RNAs. Sem Cell & Dev Biol. 2014;34:9–14.
   PubMed Web of Science ®Google Scholar
• Wang Y, Xu Z, Jiang J, et al. Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal. Dev Cell. 2013;25:69–80.
   PubMed Web of Science ®Google Scholar
• Cesana M, Cacchiarelli D, Legnini I, et al. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell 2011;147:358–369.
   PubMed Web of Science ®Google Scholar
• Zhang DD, Wang WT, Xiong J, et al. Long noncoding RNA LINC00305 promotes inflammation by activating the AHRR-NF-kappaB pathway in human monocytes. Sci Rep. 2017;7:46204.
   PubMed Web of Science ®Google Scholar
• Zhang BY, Jin Z, Zhao Z. Long intergenic noncoding RNA 00305 sponges miR-136 to regulate the hypoxia induced apoptosis of vascular endothelial cells. Biomed Pharmacother. 2017;94:238–243.
   PubMed Web of Science ®Google Scholar
• Huang S, Ge X, Yu J, et al. Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons. FASEB J: Offic Publ Feder Am Soc Exper Biol. 2018;32:512–528.
   PubMed Web of Science ®Google Scholar
• Sun Y, Li Q, Gui H, et al. MicroRNA-124 mediates the cholinergic anti-inflammatory action through inhibiting the production of pro-inflammatory cytokines. Cell Res. 2013;23:1270–1283.
   PubMed Web of Science ®Google Scholar
• Nakamachi Y, Ohnuma K, Uto K, et al. MicroRNA-124 inhibits the progression of adjuvant-induced arthritis in rats. Ann Rheum Dis. 2016;75:601–608.
   PubMed Web of Science ®Google Scholar
• Wang XN, Zhang LH, Cui XD, et al. lncRNA HOXA11-AS is involved in fracture healing through regulating mir-124-3p. Euro Rev Med Pharmacol Sci. 2017;21:4771–4776.
   PubMed Web of Science ®Google Scholar
• Lieberthal J, Sambamurthy N, Scanzello CR. Inflammation in joint injury and post-traumatic osteoarthritis. Osteoarthr Cartil. 2015;23:1825–1834.
   PubMed Web of Science ®Google Scholar
• Stannus O, Jones G, Cicuttini F, et al. Circulating levels of IL-6 and TNF-alpha are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults. Osteoarthr Cartil. 2010;18:1441–1447.
   PubMed Web of Science ®Google Scholar
• Yao Y, Wang Y. ATDC5: an excellent in vitro model cell line for skeletal development. J Cell Biochem. 2013;114:1223–1229.
   PubMed Web of Science ®Google Scholar
• Nasi S, So A, Combes C, et al. Interleukin-6 and chondrocyte mineralisation act in tandem to promote experimental osteoarthritis. Ann Rheum Dis. 2016;75:1372–1379.
   PubMed Web of Science ®Google Scholar
• Lopez-Armada MJ, Carames B, Lires-Dean M, et al. Cytokines, tumor necrosis factor-alpha and interleukin-1beta, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes. Osteoarthr Cartil. 2006;14:660–669.
   PubMed Web of Science ®Google Scholar
• Ajekigbe B, Cheung K, Xu Y, et al. Identification of long non-coding RNAs expressed in knee and hip osteoarthritic cartilage. Osteoarthr Cartil. 2019;27:694–702.
   PubMed Web of Science ®Google Scholar
• Mathy NW, Chen XM. Long non-coding RNAs (lncRNAs) and their transcriptional control of inflammatory responses. J Biol Chem. 2017;292:12375–12382.
   PubMed Web of Science ®Google Scholar
• Carpenter S, Fitzgerald KA. Cytokines and long noncoding RNAs. Cold Spring Harbor Persp Biol. 2018;10:a028589.
   PubMed Web of Science ®Google Scholar
• Alexander M, O'Connell RM. Noncoding RNAs and chronic inflammation: micro-managing the fire within. BioEssays: News and Rev Mol, Cell Dev Biol. 2015;37:1005–1015.
   Web of Science ®Google Scholar
• Nugent M. MicroRNAs: exploring new horizons in osteoarthritis. Osteoarthr Cartil. 2016;24:573–580.
   PubMed Web of Science ®Google Scholar
• Zhou L, Wang J, Li J, et al. 1,25-Dihydroxyvitamin D3 ameliorates collagen-induced arthritis via suppression of Th17 cells through miR-124 mediated inhibition of IL-6 signaling. Front Immunol. 2019;10:178.
   PubMed Web of Science ®Google Scholar
• Guan YJ, Li J, Yang X, et al. Evidence that miR-146a attenuates aging- and trauma-induced osteoarthritis by inhibiting Notch1, IL-6, and IL-1 mediated catabolism. Aging Cell. 2018;17:e12752.
   PubMed Web of Science ®Google Scholar
• Murahashi Y, Yano F, Kobayashi H, et al. Intra-articular administration of IkappaBalpha kinase inhibitor suppresses mouse knee osteoarthritis via downregulation of the NF-kappaB/HIF-2alpha axis. Sci Rep. 2018;8:16475.
   PubMed Web of Science ®Google Scholar
• Qiu S, Feng Y, LeSage G, et al. Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6. J Immunol (Baltimore, Md: 1950). 2015;194:1021–1030.
   PubMed Web of Science ®Google Scholar