Knockdown of lncRNA LSINCT5 suppresses growth and metastasis of human glioma cells via up-regulating miR-451

References

• Li Y, Ma X, Wang Y, et al. miR-489 inhibits proliferation, cell cycle progression and induces apoptosis of glioma cells via targeting SPIN1-mediated PI3K/AKT pathway. Biomed Pharmacother. 2017;93:435–443.
   PubMed Web of Science ®Google Scholar
• Ma CC, Xiong Z, Zhu GN, et al. Long non-coding RNA ATB promotes glioma malignancy by negatively regulating miR-200a. J Exp Clin Cancer Res CR. 2016;35:90.
   PubMed Web of Science ®Google Scholar
• Chistiakov DA, Chekhonin VP. Extracellular vesicles shed by glioma cells: pathogenic role and clinical value. Tumor Biol. 2014;35:8425–8438.
   PubMedGoogle Scholar
• Bolha L, Ravnik-Glavac M. Long noncoding RNAs as biomarkers in cancer. Dis Markers. 2017;2017:7243968.
   PubMed Web of Science ®Google Scholar
• Prensner JR, Chinnaiyan AM. The emergence of lncRNAs in cancer biology. Cancer Discov. 2011;1:391–407.
   PubMed Web of Science ®Google Scholar
• Perez DS, Hoage TR, Pritchett JR, et al. Long, abundantly expressed non-coding transcripts are altered in cancer. Hum Mol Genet. 2008;17:642–655.
   PubMed Web of Science ®Google Scholar
• Smith DI, Jessica SM. Abstract A1: long stress-induced non-coding transcripts (LSINCTs) and cancer. Cancer Res. 2012;72:A1–A1.
   Google Scholar
• Xu MD, Qi P, Weng WW, et al. Long non-coding RNA LSINCT5 predicts negative prognosis and exhibits oncogenic activity in gastric cancer. Medicine. 2014;93:e303.
   PubMed Web of Science ®Google Scholar
• Silva JM, Boczek NJ, Berres MW, et al. LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation. RNA Biol. 2011;8:496–505.
   PubMed Web of Science ®Google Scholar
• Zhang X, Sha M, Yao Y, et al. Increased B-type-natriuretic peptide promotes myocardial cell apoptosis via the B-type-natriuretic peptide/long non-coding RNA LSINCT5/caspase-1/interleukin 1beta signaling pathway. Mol Med Rep. 2015;12:6761–6767.
   PubMed Web of Science ®Google Scholar
• Yu F, Lu Z, Cai J, et al. MALAT1 functions as a competing endogenous RNA to mediate Rac1 expression by sequestering miR-101b in liver fibrosis. Cell Cycle (Georgetown, Tex). 2015;14:3885–3896.
   PubMed Web of Science ®Google Scholar
• Rubio-Somoza I, Weigel D, Franco-Zorilla JM, et al. ceRNAs: miRNA target mimic mimics. Cell. 2011;147:1431–1432.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Dutta A, Abounader R. The role of microRNAs in glioma initiation and progression. Front Biosci. 2012;17:700–712.
   Web of Science ®Google Scholar
• Iorio MV, Croce CM. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med. 2012;4:143–159.
   PubMed Web of Science ®Google Scholar
• Tian Y, Nan Y, Han LEI, et al. MicroRNA miR-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma. Int J Oncol. 2012;40:1105–1112.
   PubMed Web of Science ®Google Scholar
• Li R, Li X, Ning S, et al. Identification of a core miRNA-pathway regulatory network in glioma by therapeutically targeting miR-181d, miR-21, miR-23b, β-catenin, CBP, and STAT3. PloS One. 2014;9:e101903.
   PubMed Web of Science ®Google Scholar
• Godlewski J, Nowicki MO, Bronisz A, et al. MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Mol Cell. 2010;37:620–632.
   PubMed Web of Science ®Google Scholar
• Nan Y, Guo H, Guo L, et al. MiRNA-451 inhibits glioma cell proliferation and invasion through the mTOR/HIF-1alpha/VEGF signaling pathway by targeting CAB39. Hum Gene Ther Clini Dev. 2018;29:156–166.
   PubMed Web of Science ®Google Scholar
• Zhao K, Wang L, Li T, et al. The role of miR-451 in the switching between proliferation and migration in malignant glioma cells: AMPK signaling, mTOR modulation and Rac1 activation required. Int J Oncol. 2017;50:1989–1999.
   PubMed Web of Science ®Google Scholar
• Godlewski J, Bronisz A, Nowicki MO, et al. microRNA-451: a conditional switch controlling glioma cell proliferation and migration. Cell Cycle (Georgetown, Tex). 2010;9:2742–2748.
   PubMed Web of Science ®Google Scholar
• Nan Y, Han L, Zhang A, et al. MiRNA-451 plays a role as tumor suppressor in human glioma cells. Brain Res. 2010;1359:14–21.
   PubMed Web of Science ®Google Scholar
• Kim Y, Roh S, Lawler S, et al. miR451 and AMPK mutual antagonism in glioma cell migration and proliferation: a mathematical model. PLoS One. 2011;6:e28293.
   PubMed Web of Science ®Google Scholar
• Alural B, Ayyildiz ZO, Tufekci KU, et al. Erythropoietin promotes glioblastoma via miR-451 suppression. Vitam Horm. 2017;105:249–271.
   PubMed Web of Science ®Google Scholar
• Nakada M, Drake KL, Nakada S, et al. Ephrin-B3 ligand promotes glioma invasion through activation of Rac1. Cancer Res. 2006;66:8492–8500.
   PubMed Web of Science ®Google Scholar
• Cardama GA, Gonzalez N, Ciarlantini M, et al. Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells. Onco Targets Ther. 2014;7:2021–2033.
   PubMed Web of Science ®Google Scholar
• Jiang L, Lin C, Song L, et al. MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop. J Clin Invest. 2012;122:33–47.
   PubMed Web of Science ®Google Scholar
• Gong A, Huang S. FoxM1 and Wntβ-catenin signaling in glioma stem cells. Cancer Res. 2012;72:5658–5662.
   PubMed Web of Science ®Google Scholar
• Li X, Wu C, Chen N, et al. PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma. Oncotarget. 2016;7:33440–33450.
   PubMed Web of Science ®Google Scholar
• Nazari M, Nasiri M, Ghaderi A. Evaluation of long stress-induced non-coding transcripts 5 polymorphism in Iranian patients with bladder cancer. Res Mol Med (Rmm). 2016;4:17–21.
   Google Scholar
• Dong L, Qi P, Xu M-D, et al. Circulating CUDR, LSINCT-5 and PTENP1 long noncoding RNAs in sera distinguish patients with gastric cancer from healthy controls. Int J Cancer. 2015;137:1128–1135.
   PubMed Web of Science ®Google Scholar
• Bergamaschi A, Katzenellenbogen BS. Tamoxifen downregulation of miR-451 increases 14-3-3[zeta] and promotes breast cancer cell survival and endocrine resistance. Oncogene. 2012;31:39–47.
   PubMed Web of Science ®Google Scholar
• Li HP, Zeng XC, Zhang B, et al. miR-451 inhibits cell proliferation in human hepatocellular carcinoma through direct suppression of IKK-beta. Carcinogenesis. 2013;34:2443–2451.
   PubMed Web of Science ®Google Scholar
• Orgaz JL, Herraiz C, Sanz-Moreno V. Rho GTPases modulate malignant transformation of tumor cells. Small GTPases. 2014;5:e29019.
   PubMedGoogle Scholar
• Senger DL, Tudan C, Guiot MC, et al. Suppression of Rac activity induces apoptosis of human glioma cells but not normal human astrocytes. Cancer Res. 2002;62:2131.
   PubMed Web of Science ®Google Scholar
• Man J, Shoemake J, Zhou W, et al. Sema3C promotes the survival and tumorigenicity of glioma stem cells through Rac1 activation. Cell Rep. 2014;9:1812–1826.
   PubMed Web of Science ®Google Scholar
• Bid HK, Roberts RD, Manchanda PK, et al. RAC1: an emerging therapeutic option for targeting cancer angiogenesis and metastasis. Mol Cancer Ther. 2013;12:1925–1934.
   PubMed Web of Science ®Google Scholar
• Myant Kevin B, Cammareri P, McGhee Ewan J, et al. ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation. Cell Stem Cell. 2013;12:761–773.
   PubMed Web of Science ®Google Scholar
• De P, Carlson JH, Jepperson T, et al. RAC1 GTP-ase signals Wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers. Oncotarget. 2017;8:3072–3103.
   PubMedGoogle Scholar
• Gastonguay A, Berg T, Hauser AD, et al. The role of Rac1 in the regulation of NF-kB activity, cell proliferation, and cell migration in non-small cell lung carcinoma. Cancer Biol Ther. 2012;13:647–656.
   PubMed Web of Science ®Google Scholar
• Qu H, Sun H, Wang X. Neogenin-1 promotes cell proliferation, motility, and adhesion by up-regulation of zinc finger E-box binding homeobox 1 via activating the Rac1/PI3K/AKT pathway in gastric cancer cells. Cell Physiol Biochem. 2018;48:1457–1467.
   PubMedGoogle Scholar