Osteoclastic activity was associated with the development of steroid-induced osteonecrosis of femoral head

References

• Yu K, Tan H, Xu Y. [Research progress of experimental animal models of avascular necrosis of femoral head]. Zhon Xiu Chong Jian Wai Zhi. 2015;29(12):1564–1569.
   PubMedGoogle Scholar
• Kubo T, Ueshima K, Saito M, et al. Clinical and basic research on steroid-induced osteonecrosis of the femoral head in Japan. J Orthop Sci. 2016;21(4):407–413.
   PubMed Web of Science ®Google Scholar
• Liu L, Gao F, Sun W, et al. Investigating clinical failure of core decompression with autologous bone marrow mononuclear cells grafting for the treatment of non-traumatic osteonecrosis of the femoral head. Int Orthop. 2018;42(7):1575–1583.
   PubMed Web of Science ®Google Scholar
• Griffith JF, Antonio GE, Kumta SM, et al. Osteonecrosis of hip and knee in patients with severe acute respiratory syndrome treated with steroids. Radiology. 2005;235(1):168–175.
   PubMed Web of Science ®Google Scholar
• Mont MA, Zywiel MG, Marker DR, et al. The natural history of untreated asymptomatic osteonecrosis of the femoral head: a systematic literature review. J Bone Joint Surg Am Vol. 2010;92(12):2165–2170.
   PubMed Web of Science ®Google Scholar
• Mont MA, Marulanda GA, Jones LC, et al. Systematic analysis of classification systems for osteonecrosis of the femoral head. J Bone Joint Surg Am. 2006;88(3):16–26.
   PubMed Web of Science ®Google Scholar
• He M, Gong SD, Chen XJ, et al. Plasma C-terminal cross-linking telopeptide of type II collagen as a biomarker in advanced stages of femoral head osteonecrosis. Biomed Pharmacother. 2019;111:1213–1220.
   PubMed Web of Science ®Google Scholar
• Gong SD, Chen XJ, Chen ZQ, et al. Elevated plasma cartilage oligomeric matrix protein (COMP) level are associated with the progression of non-traumatic osteonecrosis of femoral head. Clin Chim Acta. 2019;490:214–221.
   PubMed Web of Science ®Google Scholar
• Chen XJ, Yang F, Chen ZQ, et al. Association of reduced sclerostin expression with collapse process in patients with osteonecrosis of the femoral head. Int Orthop. 2018;42(7):1675–1682.
   PubMed Web of Science ®Google Scholar
• Zhou X, Yishake M, Li J, et al. Genetic susceptibility to prosthetic joint infection following total joint arthroplasty: a systematic review. Gene. 2015;563(1):76–82.
   PubMed Web of Science ®Google Scholar
• Bonfa AC, Seguro LP, Caparbo V, et al. RANKL and OPG gene polymorphisms: associations with vertebral fractures and bone mineral density in premenopausal systemic lupus erythematosus. Osteoporos Int. 2015;26(5):1563–1571.
   PubMed Web of Science ®Google Scholar
• Aubin JE, Bonnelye E. Osteoprotegerin and its ligand: a new paradigm for regulation of osteoclastogenesis and bone resorption. Osteoporos Int. 2000;11(11):905–913.
   PubMed Web of Science ®Google Scholar
• Kostenuik PJ. Osteoprotegerin and RANKL regulate bone resorption, density, geometry and strength. Curr Opin Pharmacol. 2005;5(6):618–625.
   PubMed Web of Science ®Google Scholar
• Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 1998;93(2):165–176.
   PubMed Web of Science ®Google Scholar
• Wada T, Nakashima T, Hiroshi N, et al. RANKL-RANK signaling in osteoclastogenesis and bone disease. Trends Mol Med. 2006;12(1):17–25.
   PubMed Web of Science ®Google Scholar
• Leibbrandt A, Penninger JM. RANK/RANKL: regulators of immune responses and bone physiology. Ann N Y Acad Sci. 2008;1143:123–150.
   PubMed Web of Science ®Google Scholar
• Rushbrook JP. The effects of alcohol in orthopaedic patients. Orthopaed Trauma. 2013;27:7.
   Google Scholar
• Celik A, Tekis D, Saglam F, et al. Association of corticosteroids and factor V, prothrombin, and MTHFR gene mutations with avascular osteonecrosis in renal allograft recipients. Transplant Proc. 2006;38(2):512–516.
   PubMed Web of Science ®Google Scholar
• Sugano N, Atsumi T, Ohzono K, et al. The 2001 revised criteria for diagnosis, classification, and staging of idiopathic osteonecrosis of the femoral head. J Orthop Sci. 2002;7(5):601–605.
   PubMedGoogle Scholar
• Floerkemeier T, Hirsch S, Budde S, et al. Bone turnover markers failed to predict the occurrence of osteonecrosis of the femoral head: a preliminary study. J Clin Lab Anal. 2012;26(2):55–60.
   PubMed Web of Science ®Google Scholar
• Rathinavelu S, Guidry-Elizondo C, Banu J. Molecular modulation of osteoblasts and osteoclasts in type 2 diabetes. J Diabetes Res. 2018;2018:6354787.
   PubMed Web of Science ®Google Scholar
• Wang C, Wang X, Xu XL, et al. Bone microstructure and regional distribution of osteoblast and osteoclast activity in the osteonecrotic femoral head. PLOS One. 2014;9(5):e96361.
   PubMed Web of Science ®Google Scholar
• Boyan BD, Schwartz Z, Lohmann CH, et al. Pretreatment of bone with osteoclasts affects phenotypic expression of osteoblast-like cells. J Orthop Res. 2003;21(4):638–647.
   PubMed Web of Science ®Google Scholar
• Perez-Amodio S, Beertsen W, Everts V. (Pre-)osteoclasts induce retraction of osteoblasts before their fusion to osteoclasts. J Bone Miner Res. 2004;19(10):1722–1731.
   PubMed Web of Science ®Google Scholar
• Cao HJ, Zheng LZ, Wang N, et al. Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity – an in vitro mechanism study for preventing destructive repair of osteonecrosis. Bone. 2015;74:58–68.
   PubMed Web of Science ®Google Scholar
• Kim HKW, Aruwajoye O, Du J, et al. Local administration of bone morphogenetic protein-2 and bisphosphonate during non-weight-bearing treatment of ischemic osteonecrosis of the femoral head: an experimental investigation in immature pigs. J Bone Joint Surg Am Vol. 2014;96(18):1515–1524.
   PubMed Web of Science ®Google Scholar
• Hruska KA, Mathew S, Saab G. Bone morphogenetic proteins in vascular calcification. Circ Res. 2005;97(2):105–114.
   PubMed Web of Science ®Google Scholar
• Sung B, Prasad S, Yadav VR, et al. RANKL signaling and osteoclastogenesis is negatively regulated by cardamonin. PLOS One. 2013;8(5):e64118.
   PubMed Web of Science ®Google Scholar
• Mandelin J, Li TF, Liljestrom M, et al. Imbalance of RANKL/RANK/OPG system in interface tissue in loosening of total hip replacement. J Bone Joint Surg Br Vol. 2003;85-B(8):1196–1201.
   Google Scholar
• Miao Q, Hao S, Li H, et al. Expression of osteoprotegerin, RNAK and RANKL genes in femoral head avascular necrosis and related signaling pathway. Int J Clin Exp Pathol. 2015;8(9):10460–10467.
   PubMed Web of Science ®Google Scholar
• Samara S, Dailiana Z, Chassanidis C, et al. Expression profile of osteoprotegerin, RANK and RANKL genes in the femoral head of patients with avascular necrosis. Exp Mol Pathol. 2014;96(1):9–14.
   PubMed Web of Science ®Google Scholar
• Xiong MY, Liu LQ, Liu SQ, et al. Effects of osteoprotegerin, RANK and RANKL on bone destruction and collapse in avascular necrosis femoral head. Am J Translat Res. 2016;8(7):3133–3140.
   PubMed Web of Science ®Google Scholar