Injectable oxygenation therapeutics: evaluating the oxygen delivery efficacy of artificial oxygen carriers and kosmotropes in vitro

References

• Spiess BD. Perfluorocarbon emulsions as a promising technology: a review of tissue and vascular gas dynamics. J Appl Physiol. 2009;106(4):1444–1452.
   PubMed Web of Science ®Google Scholar
• Graham K, Moon-Massat PF, Unger EC. 2017 Military supplement: dodecafluoropentane emulsion (DDFPe) as a resuscitation fluid for treatment of hemorrhagic shock and traumatic brain injury: a review. Shock. 2019;52:50–54.
   PubMed Web of Science ®Google Scholar
• Mullah SH, Saha BK, Abutarboush R, et al. Perfluorocarbon NVX-108 increased cerebral oxygen tension after traumatic brain injury in rats. Brain Res. 2016;1634:132–139.
   PubMed Web of Science ®Google Scholar
• Cheung AT, To PL, Chan DM, et al. Comparison of treatment modalities for hemorrhagic shock. Artif Cells Blood Substit Immobil Biotechnol. 2007;35(2):173–190.
   PubMed Web of Science ®Google Scholar
• Brown AT, Arthur MC, Nix JS, et al. Dodecafluoropentane emulsion (DDFPe) decreases stroke size and improves neurological scores in a permanent occlusion rat stroke model. Open Neurol J. 2014;8:27–33.
   PubMedGoogle Scholar
• Culp WC, Woods SD, Skinner RD, et al. Dodecafluoropentane emulsion decreases infarct volume in a rabbit ischemic stroke model. J Vasc Interv Radiol. 2012;23(1):116–121.
   PubMed Web of Science ®Google Scholar
• Kawaguchi AT. Artificial oxygen carriers: a clinical point of view. Artif Organs. 2009;33(2):97–99.
   PubMed Web of Science ®Google Scholar
• Remy B, Deby-Dupont G, Lamy M. Red blood cell substitutes: fluorocarbon emulsions and haemoglobin solutions. Br Med Bull. 1999;55(1):277–298.
   PubMed Web of Science ®Google Scholar
• Riess JG. Understanding the fundamentals of perfluorocarbons and perfluorocarbon emulsions relevant to in vivo oxygen delivery. Artif Cells Blood Substit Immobil Biotechnol. 2005;33(1):47–63.
   PubMed Web of Science ®Google Scholar
• Spiess BD. Basic mechanisms of gas transport and past research using perfluorocarbons. Diving Hyperb Med. 2010;40(1):23–28.
   PubMed Web of Science ®Google Scholar
• Riess JG, Le Blanc M. Solubility and transport phenomena in perfluorochemicals relevant to blood substitution and other biomedical applications. Pure Appl Chem. 1982;54(12):2383–2406.
   Web of Science ®Google Scholar
• Jayaraman MS, Graham K, Unger EC. In vitro model to compare the oxygen offloading behaviour of dodecafluoropentane emulsion (DDFPe). Artif Cells Nanomed Biotechnol. 2019;47(1):783–789.
   PubMed Web of Science ®Google Scholar
• Johnson JL, Dolezal MC, Kerschen A, et al. In vitro comparison of dodecafluoropentane (DDFP), perfluorodecalin (PFD), and perfluoroctylbromide (PFOB) in the facilitation of oxygen exchange. Artif Cells Blood Substit Immobil Biotechnol. 2009;37(4):156–162.
   PubMed Web of Science ®Google Scholar
• Johnson JLH. 2017. Oxygen carriers: are they enough for cellular support? In: Lapchak PA, Zhang JH, editors. Neuroprotective therapy for stroke and ischemic disease. Cham: Springer International Publishing. p. 621–640.
   Google Scholar
• Casanova-Morales N, Alavi Z, Wilson CAM, et al. Identifying chaotropic and kosmotropic agents by nanorheology. J Phys Chem B. 2018;122(14):3754–3759.
   PubMed Web of Science ®Google Scholar
• Holland RA, Shibata H, Scheid P, et al. Kinetics of O2 uptake and release by red cells in stopped-flow apparatus: effects of unstirred layer. Respir Physiol. 1985;59(1):71–91.
   PubMedGoogle Scholar
• Huxley VH, Kutchai H. The effect of the red cell membrane and a diffusion boundary layer on the rate of oxygen uptake by human erythrocytes. J Physiol. 1981;316:75–83.
   PubMed Web of Science ®Google Scholar
• Gainer JL, Sheehan JP, Larner JM, et al. Trans sodium crocetinate with temozolomide and radiation therapy for glioblastoma multiforme. J Neurosurg. 2017;126(2):460–466.
   PubMed Web of Science ®Google Scholar
• Johnson JL, Unger E. 2014. Buffered oxygen therapeutic. United States Patent 8,822,549, September 2, 2014.
   Google Scholar
• Gainer JL. 1996. Trans-sodium crocetinate, methods of making and methods of use thereof. United States Patent 6,060,511.
   Google Scholar
• Culp WC, Onteddu SS, Brown A, et al. Dodecafluoropentane emulsion in acute ischemic stroke: a phase Ib/II randomized and controlled dose-escalation trial. J Vasc Interv Radiol. 2019;30(8):1244–1250 e1241.
   PubMed Web of Science ®Google Scholar
• Kreimeier U. Pathophysiology of fluid imbalance. Crit Care. 2000;4(Suppl 2):S3–S7.
   PubMed Web of Science ®Google Scholar
• Pittman RN. 2011. Regulation of tissue oxygenation. In: Neil Grange D, Granger JP, editors. Integrated systems physiology: from molecule to function to disease. San Rafael (CA): Morgan & Claypool Life Sciences.
   Google Scholar
• Gainer JL. Trans-sodium crocetinate for treating hypoxia/ischemia. Expert Opin Investig Drugs. 2008;17(6):917–924.
   PubMed Web of Science ®Google Scholar
• Dunn J-OC, Mythen MG, Grocott MP. Physiology of oxygen transport. BJA Education. 2016;16(10):341–348.
   Web of Science ®Google Scholar
• Popel AS. Theory of oxygen transport to tissue. Crit Rev Biomed Eng. 1989;17(3):257–321.
   PubMed Web of Science ®Google Scholar
• Sandor B, Marin M, Lapoumeroulie C, et al. Effects of Poloxamer 188 on red blood cell membrane properties in sickle cell anaemia. Br J Haematol. 2016;173(1):145–149.
   PubMed Web of Science ®Google Scholar
• Ballas SK, Files B, Luchtman-Jones L, et al. Safety of purified poloxamer 188 in sickle cell disease: phase I study of a non-ionic surfactant in the management of acute chest syndrome. Hemoglobin. 2004;28(2):85–102.
   PubMed Web of Science ®Google Scholar