CD44-targeted pH-responsive micelles for enhanced cellular internalization and intracellular on-demand release of doxorubicin

References

• Jin X, Zhou J, Zhang Z, et al. Doxorubicin combined with betulinic acid or lonidamine in RGD ligand-targeted pH-sensitive micellar system for ovarian cancer treatment. Int J Pharm. 2019;571:118751.
   PubMed Web of Science ®Google Scholar
• Setayesh A, Bagheri F, Boddohi S. Self-assembled formation of chondroitin sulfate-based micellar nanogel for curcumin delivery to breast cancer cells. Int J Biol Macromol. 2020;161:771–778.
   PubMed Web of Science ®Google Scholar
• Sun X, Wang G, Zhang H, et al. The blood clearance kinetics and pathway of polymeric micelles in cancer drug delivery. ACS Nano. 2018;12(6):6179–6192.
   PubMed Web of Science ®Google Scholar
• Talelli M, Barz M, Rijcken CJ, et al. Core-crosslinked polymeric micelles: principles, preparation, biomedical applications and clinical translation. Nano Today. 2015;10(1):93–117.
   PubMed Web of Science ®Google Scholar
• Eetezadi S, Ekdawi SN, Allen C. The challenges facing block copolymer micelles for cancer therapy: In vivo barriers and clinical translation. Adv Drug Deliv Rev. 2015;91:7–22.
   PubMed Web of Science ®Google Scholar
• Wicki A, Witzigmann D, Balasubramanian V, et al. Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications. J Control Release. 2015;200:138–157.
   PubMed Web of Science ®Google Scholar
• Pan J, Lei S, Chang L, et al. Smart pH-responsive nanoparticles in a model tumor microenvironment for enhanced cellular uptake. J Mater Sci. 2019;54(2):1692–1702.
   Web of Science ®Google Scholar
• Zhou L, Xi Y, Chen M, et al. A highly antibacterial polymeric hybrid micelle with efficiently targeted anticancer siRNA delivery and anti-infection in vitro/in vivo. Nanoscale. 2018;10(36):17304–17317.
   PubMed Web of Science ®Google Scholar
• Emtiazi G, Zohrabi T, Lee LY, et al. Covalent diphenylalanine peptide nanotube conjugated to folic acid/magnetic nanoparticles for anti-cancer drug delivery. J Drug Delivery Sci Technol. 2017;41:90–98.
   Web of Science ®Google Scholar
• Hijaz M, Das S, Mert I, et al. Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer. BMC Cancer. 2016;16:220.
   PubMed Web of Science ®Google Scholar
• Li Y, Chen M, Yao B, et al. Transferrin receptor-targeted redox/pH-sensitive podophyllotoxin prodrug micelles for multidrug-resistant breast cancer therapy. J Mater Chem B. 2019;7(38):5814–5824.
   PubMed Web of Science ®Google Scholar
• Debele TA, Yu LY, Yang CS, et al. pH- and GSH-sensitive hyaluronic acid-MP conjugate micelles for intracellular delivery of doxorubicin to colon cancer cells and cancer stem cells. Biomacromolecules. 2018;19(9):3725–3737.
   PubMed Web of Science ®Google Scholar
• Wang Q, Zhong Y, Liu W, et al. Enhanced chemotherapeutic efficacy of the low-dose doxorubicin in breast cancer via nanoparticle delivery system crosslinked hyaluronic acid. Drug Deliv. 2019;26(1):12–22.
   PubMed Web of Science ®Google Scholar
• Qiu L, Hu Q, Cheng L, et al. cRGDyK modified pH responsive nanoparticles for specific intracellular delivery of doxorubicin. Acta Biomater. 2016;30:285–298.
   PubMed Web of Science ®Google Scholar
• Harrison EB, Azam SH, Pecot CV. Targeting accessories to the crime: nanoparticle nucleic acid delivery to the tumor microenvironment. Front Pharmacol. 2018;9:307.
   PubMed Web of Science ®Google Scholar
• Zhang B, Hu Y, Pang Z. Modulating the tumor microenvironment to enhance tumor nanomedicine delivery. Front Pharmacol. 2017;8:952
   PubMed Web of Science ®Google Scholar
• Kuchuk O, Tuccitto A, Citterio D, et al. pH regulators to target the tumor immune microenvironment in human hepatocellular carcinoma. Oncoimmunology. 2018;7(7):e1445452.
   PubMed Web of Science ®Google Scholar
• Tang S, Meng Q, Sun H, et al. Dual pH-sensitive micelles with charge-switch for controlling cellular uptake and drug release to treat metastatic breast cancer. Biomaterials. 2017;114:44–53.
   PubMed Web of Science ®Google Scholar
• Li X, Gao M, Xin K, et al. Singlet oxygen-responsive micelles for enhanced photodynamic therapy. J Control Release. 2017;260:12–21.
   PubMed Web of Science ®Google Scholar
• Kanamala M, Wilson WR, Yang M, et al. Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: a review. Biomaterials. 2016;85:152–167.
   PubMed Web of Science ®Google Scholar
• Mu Y, Wu G, Su C, et al. pH-sensitive amphiphilic chitosan-quercetin conjugate for intracellular delivery of doxorubicin enhancement. Carbohydr Polym. 2019;223:115072.
   PubMed Web of Science ®Google Scholar
• Miao J, Yang XQ, Gao Z, et al. Redox-responsive chitosan oligosaccharide-SS-Octadecylamine polymeric carrier for efficient anti-Hepatitis B Virus gene therapy. Carbohydr Polym. 2019;212:215–221.
   PubMed Web of Science ®Google Scholar
• Qu J, Peng S, Wang R, et al. Stepwise pH-sensitive and biodegradable polypeptide hybrid micelles for enhanced cellular internalization and efficient nuclear drug delivery. Colloids Surf B Biointerfaces. 2019;181:315–324.
   PubMed Web of Science ®Google Scholar
• Ravar F, Saadat E, Gholami M, et al. Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation. J Control Release. 2016;229:10–22.
   PubMed Web of Science ®Google Scholar
• Chen Y, Peng F, Song X, et al. Conjugation of paclitaxel to C-6 hexanediamine-modified hyaluronic acid for targeted drug delivery to enhance antitumor efficacy. Carbohydr Polym. 2018;181:150–158.
   PubMed Web of Science ®Google Scholar
• Li F, Chen WL, You BG, et al. Enhanced cellular internalization and on-demand intracellular release of doxorubicin by stepwise pH-/reduction-responsive nanoparticles. ACS Appl Mater Interfaces. 2016;8(47):32146–32158.
   PubMed Web of Science ®Google Scholar
• Muley P, Kumar S, El Kourati F, et al. Hydrophobically modified inulin as an amphiphilic carbohydrate polymer for micellar delivery of paclitaxel for intravenous route. Int J Pharm. 2016;500(1–2):32–41.
   PubMed Web of Science ®Google Scholar
• Pan Y, Wang X, Yin Z. Synthesis and evaluation of cationic polymeric micelles as carriers of lumbrokinase for targeted thrombolysis. Asian J Pharm Sci. 2019;14(2):144–153.
   PubMed Web of Science ®Google Scholar
• Wu Z, Chen B, Gan Z, et al. Exogenous vitamin C-triggered surface charge conversion of pH/reduction-responsive micelles for the enhanced tumor-specific activity of loaded doxorubicin. Mol Pharm. 2020;17(3):954–964.
   PubMed Web of Science ®Google Scholar
• Chen WL, Yang SD, Li F, et al. Tumor microenvironment-responsive micelles for pinpointed intracellular release of doxorubicin and enhanced anti-cancer efficiency. Int J Pharm. 2016;511(2):728–740.
   PubMed Web of Science ®Google Scholar
• Hsu JC, Naha PC, Lau KC, et al. An all-in-one nanoparticle (AION) contrast agent for breast cancer screening with DEM-CT-MRI-NIRF imaging. Nanoscale. 2018;10(36):17236–17248.
   PubMed Web of Science ®Google Scholar
• Jafarzadeh-Holagh S, Hashemi-Najafabadi S, Shaki H, et al. Self-assembled and pH-sensitive mixed micelles as an intracellular doxorubicin delivery system. J Colloid Interface Sci. 2018;523:179–190.
   PubMed Web of Science ®Google Scholar
• Li J, Liu Y, Li H, et al. pH-Sensitive micelles with mitochondria-targeted and aggregation-induced emission characterization: synthesis, cytotoxicity and biological applications. Biomater Sci. 2018;6(11):2998–3008.
   PubMed Web of Science ®Google Scholar
• Liu Y, Zhou C, Wei S, et al. Paclitaxel delivered by CD44 receptor-targeting and endosomal pH sensitive dual functionalized hyaluronic acid micelles for multidrug resistance reversion. Colloids Surf B Biointerfaces. 2018;170:330–340.
   PubMed Web of Science ®Google Scholar
• Zhong Y, Goltsche K, Cheng L, et al. Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo. Biomaterials. 2016;84:250–261.
   PubMed Web of Science ®Google Scholar
• Liu C, Guan Y, Su Y, et al. Surface charge switchable and core cross-linked polyurethane micelles as a reduction-triggered drug delivery system for cancer therapy. RSC Adv. 2017;7(18):11021–11029.
   Web of Science ®Google Scholar
• Sun Q, Sun X, Ma X, et al. Integration of nanoassembly functions for an effective delivery cascade for cancer drugs. Adv Mater. 2014;26(45):7615–7621.
   PubMed Web of Science ®Google Scholar
• Wang L, Lv Y, Li C, et al. Transformable dual-inhibition system effectively suppresses renal cancer metastasis through blocking endothelial cells and cancer stem cells. Small. 2020;16(40):e2004548.
   PubMed Web of Science ®Google Scholar
• Zhang L, Zhou H, Belzile O, et al. Phosphatidylserine-targeted bimodal liposomal nanoparticles for in vivo imaging of breast cancer in mice. J Control Release. 2014;183:114–123.
   PubMed Web of Science ®Google Scholar
• Sui J, Cui Y, Cai H, et al. Synergistic chemotherapeutic effect of sorafenib-loaded pullulan-Dox conjugate nanoparticles against murine breast carcinoma. Nanoscale. 2017;9(8):2755–2767.
   PubMed Web of Science ®Google Scholar