Development and Validation of Stability Indicating UV-Visible Spectrophotometric Method for Simultaneous Estimation of Neem (Azadirachtin) and Curcumin in Pharmaceutical Tablet Dosage Form

References

• Hashemi, Z.S.S., Hossain M.A. (2016). Biological activities of different neem leaf crude extracts used locally in ayurvedic medicine. Pacific Science Review A: Natural Science and Engineering. 18: 128-131.
   Google Scholar
• Maragathavalli, S., Brindha, S., Kaviyarasi, N.S., Annadurai, B., Gangwar, S.K. (2012). Antimicrobial activity in leaf extract of neem. International Journal of Science and Nature. 3(1): 110-113.
   Google Scholar
• Mohashine, M.B., Nishimura, M., Matsumura, S., Shimono, T. (2009). Antibacterial effect of the crude Azadirachta indica neem barks extract on streptococcus sobrinus. Paediatric Dental Journal. 7(4): 61-64.
   Google Scholar
• Ghimeray, A.K., Jin, K.W., Ghimire, B.K., Cho D.K. (2009). Antioxidant activity and quantitative estimation of azadirachtin and nimbin in Azadirachta indica A. Juss grown in foothills of Nepal. African Journal of Biotechnology. 8(13): 3084-3091.
   Google Scholar
• Packia Lekshmi, N.C.J., Sowmia, N., Viveka, S. (2012). The inhibiting effect of Azadirachta indica against dental pathogens. Asian Journal of Plant Science and Research. 2(1): 6-10.
   Google Scholar
• Prashant, G.M., Chandu, G.N., Murulikrishna, K.S. (2007). The effect of mango and neem extract on four organisms causing dental caries: streptococcus mutans, streptococcus salivavius, streptococcus mitis, streptococcus sanguis: An in-vitro study. Indian Journal of Dental Research. 18(14): 148-151.
   PubMedGoogle Scholar
• Sismihardjo, W., Badawi, S.S., Nishimura, M. (2007). The difference of antibacterial effect of neem leaves and stick extracts. International Chinese Journal of Dentistry. 7: 27-29.
   Google Scholar
• Phatak, A.A., Patankar, R.D., Galgatte, U.C. (2011). Antimicrobial activity of a poly-herbal extract against dental micro flora. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2(2): 533-539.
   Google Scholar
• Chatterjee, A., Saluja, M.S.N. (2011). To evaluate antigingivitis and antiplaque effect of Azadirachta indica (Neem) mouthrinse on plaque induced gingivitis: A double blind, randomized, controlled trail. J. Indian Society of Peridontology. 15(4): 398-401.
   PubMedGoogle Scholar
• Botelho, A.M., Santos, D.A.R., Martins, G.J. (2008). Efficacy of a mouth rinse based on leaves of the neem tree (Azadirachta indica) in the treatment of patients with chronic gingivitis: A double-blind, randomized, controlled trial. Journal of Medicinal Plants Research. 2(11): 341-346.
   Google Scholar
• Abu Syed, M.D., Mosaddek, M.U., Rashid, M.D. (2008). A comparative study of the anti-inflammatory effect of aqueous extract of neem leaf and dexamethasone. Bangladesh Journal of Pharmacology. 3: 44-47.
   Web of Science ®Google Scholar
• Mordue, A.J., Nisbet A.J. (2000). Azadirachtin from the Neem Tree Azadirachta indica: its action against insects. Anais da Sociedade Entomologica do Brasil 29(4): 35-45.
   Google Scholar
• Kher, A., Chaurasia, S.C. (1997). Antifungal activity of essential oils of three medical plants. Indian Drugs. 15: 41-42.
   Google Scholar
• Sultana, B., Anwar, P.R. (2007). Antioxidant activity of phenolic components present in barks of Azadirachta indica, Terminalia arjuna, Acacia nilotica, and Eugenia jambolana Lam. trees. Journal of Food Chemistry. 104: 1106-1114.
   Google Scholar
• Gogati S.S., Marathe, A.D. (1989). Anti-viral effect of Neem leaf (Azadirachta indica) extracts on chinkugunga and measles viruses. Journal of Research and Education in Indian Medicine. 8: 1-5.
   Google Scholar
• Okpanyi, S.N., Ezeukwu, G.C. (1981). Anti-inflammatory and antipyretic activities of Azadirachta indica. Planta Media. 4(1): 34-39.
   Google Scholar
• Sharma, R.A., Gescher, A.J., Steward, W.P. (2005). Curcumin: the story so far. European Journal of Cancer. 4(13): 1955-1968.
   Google Scholar
• Josephine L.J.J., Yathish, M., Wilson, B., Premakumari K.B. (2012). Formulation and evaluation of microparticles containing curcumin for colorectal cancer. Journal of Drug Delivery & Therapeutics. 2(3): 125-128.
   Google Scholar
• Agarwal B.B., Sundaram C., Malani, N., Ichikawa H. (2007). Curcumin: the Indian Solid Gold. Advances in Experimental Medicine and Biology. 595:1-75.
   PubMed Web of Science ®Google Scholar
• Kamran A., Mujeeb, M., Ahmad, A., Amir, M., Mallick, M.N., Sharma D. (2012). Validated HPTLC analysis method for quantification of variability in content of curcumin in Curcuma longa L (turmeric) collected from different geographical region of India. Asian Pacific Journal of Tropical Biomedicine. 5: 584-588.
   Google Scholar
• Sharma K.A., Agarwal, S.S., Gupta M. (2012). Development and validation of UV spectrophotometric method for the estimation of curcumin in bulk drug and pharmaceutical dosage forms. International Journal Drug Delivery Research. 4: 375-379.
   Google Scholar
• Kadam, P.V., Bhingare, C.L., Nikam, R.Y., Pawar, S.A. (2013). Development and validation of UV spectrophotometric method for the estimation of curcumin in cream formulation. Pharmaceutical Methods 4: 43-45.
   Google Scholar
• Holkar, V.V., Deepika, R., Nirmal, V., Mistry, S.K. (2015). Development and validation of UV spectrophotometric method for the estimation of curcumin in bulk and pharmaceutical formulation. World Journal of Pharmacy and Pharmaceutical Sciences. 4-1456-63.
   Google Scholar
• Kilambi, P., Hiral N.D. (2010). Simultaneous determination of curcumin and berberine in their pure form and from the combined extracts of Curcuma longa and Berberis aristata. International Journal of Applied Science and Engineering. 8: 19-26.
   Google Scholar
• Patil, S.J., Salunkhe, V.R. (2012). Simultaneous estimation of curcumin and quercetin in ayurvedic proprietary medicine by UV Spectrophotometry. International Journal of Applied Pharmaceutics. 3(2): 267-271.
   Google Scholar
• Chaudhary, H., Kohli, K., Kumar, V., Rathee, S., Rathee, P. (2011). A novel validated spectrophotometric method for simultaneous estimation of diclofenac diethylamine and curcumin in transdermal gels. Analytical Chemistry Letters. 1 (3): 224 – 233.
   Google Scholar
• Kaur, S., Kaur, L. (2014). Spectrophotometric method for simultaneous estimation of ornidazole and curcumin in pure form. The Pharma Innovation Journal. 3(5): 01-04.
   Google Scholar
• Vijay, R., Salunkhe, M.C.M. (2016). UV and HPLC method development of azadirachtin and gymnemic acid in polyherbal churna and its validation. European Journal of Pharmaceutical and Medical Research. 3(1): 324-335.
   Google Scholar
• Farooqui, N.A., Dey, A., Singh, G.N., Easwari, T.S. (2015). Analytical method development and validation for the quantitative estimation of nimbin in bulk and solid dosage form by RP-HPLC. International Journal of Pharma and Bio Sciences. 6(1): 479-490.
   Google Scholar
• Rout, K.K., Mishra, S.K. (2014). Development of a sensitive HPTLC method for quantification of nimbolide in Azadirachta indica and its dosage form. Journal of Chromatographic Science. 52: 1089-1094.
   PubMed Web of Science ®Google Scholar
• Dubhashi, S.V., Pranay, M., Singaiah, J., Satwik, V.V., Prasad L.N. (2013). Studies on extraction and HPLC Analysis of azadirachtin from kernels of neem seeds. Journal of Advanced Pharm. Education & Research. 3(1): 57-60.
   Google Scholar
• Gai, M.K., Alvarez, C., Venegas, R., Morales, J. (2011). An HPLC method for determination of azadirachtin residues in bovine muscle. Journal of Chromatographic Science. 49:327-331.
   PubMed Web of Science ®Google Scholar
• Ji, L., Jiang, Y., Wen, J., Fan, G., Wu, Y., Zhang, C. (2009). A rapid and simple HPLC method for the determination of curcumin in rat plasma: assay development, validation and application to a pharmacokinetic study of curcumin liposome. Biomedical Chromatography. 23: 1201-1207.
   PubMed Web of Science ®Google Scholar
• Kim, D.W., Yousaf, A.M., Li, D.X., Kim, J.K., Yong, C.K., Cho, K.C. (2017). Development of RP-HPLC method for simultaneous determination of docetaxel and curcumin in rat plasma: validation and stability. Asian Journal of Pharmaceutical Sciences. 12: 105-113.
   PubMed Web of Science ®Google Scholar
• Ramshankar, Y.Y., Suresh, S., Pandit, V., Puranik, S.B. (2009). Reverse phase high performance liquid chromatographic method for the estimation of curcumin. Oriental Journal of Chemistry. 25(1): 105-110.
   Google Scholar
• Panigrahi, S., Hirlekar, R. (2016). A new stability-indicating RP-HPLC method for determination of Curcumin: An application to nanoparticulate formulation. International Journal Pharmacy and Pharmaceutical Sciences. 8(12): 149-155.
   Google Scholar
• ICH Tripartite Guidelines. (2005). Q2R1 Validation of Analytical Procedures: Text and Methodology, ICH, Geneva, Switzerland.
   Google Scholar
• ICH Tripartite Guidelines. (1996). Q2B Validation of Analytical Procedures: Text and Methodology, ICH, Geneva, Switzerland.
   Google Scholar
• Yadav, R.V., Suresh, S. (2009). Effect of cyclodextrin complexation of curcumin on its solubility and antiangiogenic and anti-inûammatory activity in rat colitis model. AAPS Pharm Sci Tech. 10(3): 752-762.
   PubMed Web of Science ®Google Scholar
• Kumar B.K., Thiruvengada V.S., Begum N.T. (2012). Analytical method development and validation of lidocaine in ointment formulation by UV spectrophotometric method. International Journal Pharmacy and Pharmaceutical Sciences. 4: 610-614.
   Google Scholar
• Beckett, A.H., Stenlake, J.B. (2005). Practical pharmaceutical chemistry. Part Two. CBS publishers and distributors, New Delhi, India. 4: 275-30.
   Google Scholar
• Jain, P.S., Chaudhari A.J., Patel, S.A., Patel, Z.N., Patel, D.T. (2012). Development and validation of the UV spectrophotometric method for determination of terbinafine hydrochloride in bulk and in formulation. Pharmaceutical Methods. 2: 198-202
   Google Scholar
• Sethuraman, S., Radhakrishnan, K., Solomon, T.A. (2013). Analytical method development and validation of caffeine in tablet dosage form by using UV spectroscopy. International Journal of Novel Trends in Pharmaceutical Sciences. 3: 82-86.
   Google Scholar
• Balasaheb, B.G., Balasaheb, A.K., Subhash, T.R., Jijabapu, K., Sudhakar, P.S. (2015). Development and validation of UV spectrophotometric method for estimation of dolutegravir sodium in tablet dosage form. Malaysian Journal of Analytical Sciences.19: 1156-1163.
   Google Scholar
• Desai, P., Mori, K., Patel, M. (2013). Development and validation of UV-visible spectrophotometric method for simultaneous estimation of momentasone furoate, hydroquinone and tretinoin from their pharmaceutical dosage form. International Journal of Pharmaceutical Sciences Review and Research. 21: 296-300.
   Google Scholar
• Cazedey, E.C.L., Salgado, H.R.N. (2014). Development and validation of UV spectrophotometric method for orbifloxacin assay and dissolution studies. Brazillian Journal Pharmaceutical Sciences. 50: 457-465.
   Web of Science ®Google Scholar
• Patil, S.J., Doijad, R.C., Dhumal, P.P. (2016). Development of UV-spectrophotometric method for the determination of imatinib mesylate in bulk and formulation. Asian Journal of Pharmaceutical and Clinical Research. 6: 54-57
   Google Scholar
• Sharma, D., Singh, G., Kumar, D., Singh, M. (2014). Development and validation of spectroscopic method for simultaneous estimation of Salbutamol sulphate, ambroxol hydrochloride and cetirizine hydrochloride in pharmaceutical tablet formulation: A novel technique for in-vitro dissolution studies International Journal Pharmacy and Pharmaceutical Sciences. 6: 446-452.
   Google Scholar
• Ethiraj, R., Thiruvengadam, E., Sampath, V.S., Vahid, A., Raj, J. (2014). Development and validation of stability indicating spectroscopic method for content analysis of ceftriaxone sodium in pharmaceuticals. International Scholar Research Notices. 6: 76-88.
   Google Scholar
• Rasheed, S.H., Arief, M., Gajavalli, S.R., Vani, S.P., Rao, K.S., Kumar, S., Rao, T.A., Hussain, S.S. (2011). Comparison of different superdisintegrants in designing of fast dissolving tablets of salbutamol sulphate. Research Journal of Pharmaceutical Biological and Chemical sciences. 2(2): 155-163
   Google Scholar
• Prasad, A.R., Thireesha, B. (2018). UV-spectrophotometric method development and validation for the determination of lornoxicam in microsponges. International Journal of Applied Pharmaceutics. 10(1): 74-78.
   Google Scholar
• Gadiya, H., Maheshwari, M., Dashora, A. (2019). UV-analytical method development and validation for simultaneous estimation of dapoxetine hydrochloride and sildenafil citrate in tablet dosage form. Asian Journal of Pharmaceutical and Clinical Research. 12(1): 328-331
   Google Scholar
• Mali, S., Ahmad, S., Shastry, V.M. (2018). Development and validation of UV visible spectrophotometric method for estimation of aceclofenac and tramadol in bulk and dosage form. International Journal of Pharmaceutical Sciences and Research. 9(9): 3852-3857.
   Web of Science ®Google Scholar
• Abdelwahaba, N.S., El-Zeinyb, B.A., Tohamy, S.I. (2012). Two spectrophotometric methods for simultaneous determination of some antihyperlipidemic drugs. Journal of Pharmaceutical Analysis. 2(4): 279-284.
   PubMedGoogle Scholar
• Shaikh, J.S., Rao, N.N. (2018). Simultaneous estimation and forced degradation studies of amiloride hydrochloride and furosemide in a pharmaceutical dosage form using reverse-phase high-performance liquid chromatography method. Asian Journal of Pharmaceutical and Clinical Research.11(7): 215-221.
   Google Scholar
• Prashanth, K.N., Basavaiah, K., Xavier, C.M. (2014). Development and validation of UV-spectrophotometric methods for the determination of sumatriptan succinate in bulk and pharmaceutical dosage form and its degradation behavior under varied stress conditions. Journal of the Association of Arab Universities for Basic and Applied Sciences. 15: 43-52.
   Google Scholar
• Mondal, S., Reddy, G.S., Mondal, P., Prathyusha, V.S., Nair, A.P., Rahaman, S.T. (2018). Development and Validation of Few UV Spectrophotometric methods for the Determination of valganciclovir in bulk and pharmaceutical dosage form. Pharmaceutical Methods. 9(2): 64-68
   Google Scholar
• Blessy, M., Patel, R.D., Prajapati, P.N., Agrawal, Y.K. (2014). Development of forced degradation and stability indicating studies of drugs-A review. Journal of Pharmaceutical Analysis. 4(3):159-165.
   PubMedGoogle Scholar