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Original Articles

Cytotoxic Effect of Hederagenin on NCI-H460, Human Non-small Lung Cancer Cells and its Free Radical Scavenging Activities

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Pages 365-372 | Received 20 Aug 2016, Accepted 04 Dec 2016, Published online: 29 Dec 2016

References

  • Stewart, B.W., Wild, C.P. (2014). World Cancer Report 2014, doi:9283204298.
  • Kuete, V., Wabo, H.K., Eyong, K.O., Feussi, M.T., Wiench, B., Tane, P. et al., (2011). Anticancer Activities of Six Selected Natural Compounds of Some Cameroonian Medicinal Plants, PLoS One. 6: 4–10.
  • De Villiers, B.J., Van Vuuren, S.F., Van Zyl, R.L., Van Wyk, B.E.. (2010). Antimicrobial and antimalarial activity of Cussonia species (Araliaceae), J. Ethnopharmacol. 129: 189–196.
  • He, W., Van Puyvelde, L., Maes, L., Bosselaers, J., De Kimpe, N. (2003). Antitrichomonas in vitro activity of Cussonia holstii Engl., Nat. Prod. Res. 17: 127–133.
  • Rodriguez-hernández, D. (2015). Hederagenin as a triterpene template for the development of new antitumor compounds, doi:10.1016/j.ejmech.2015.10.006.
  • Bruker, (2009). APEX2, SAINT and SADABS, APEX II. Bruker AXS Inc., Madison, Wisconsin, USA.
  • Sheldrick, G.M. (2008). A short history of SHELX, Acta Crystallogr. Sect. A Found. Crystallogr. 64: 112–122.
  • Westrip, S.P. (2010). PublCIF: Software for editing, validating and formatting crystallographic information files, J. Appl. Crystallogr. 43: 920–925.
  • Aliyu, M., Odunola, O., Rasheed, H., Mesaik, A.M., Choudhary, M.I., Channa, I.S. et al., (2013). Molecular Mechanism of Antiproliferation Potential of Acacia Honey on NCI-H460 Cell Line Molecular Mechanism of Antiproliferation Potential of Acacia Honey on NCI-H460 Cell Line, Nutr. Cancer. 65: 296–304.
  • Gulcin, I., Alici, A.H., Cesur, M. (2005). Determination of in Vitro Antioxidant and Radical Scavenging Activities of Propofol, Chem. Pharm. Bull. (Tokyo). 53: 281–285.
  • Oladimeji, A.O., Aliyu, M.B.,. Lanre, A., Babatunde, O., Adeniran, O.I. (2016). Identification and comparison of the volatile constituents of fresh and dried leaves of Spondias mombin found in North-central Nigeria: in vitro evaluation of their cytotoxic and antioxidant activities, 209: doi:10.1080/13880209.2016.1178308.
  • Laszczyk, M.N. (2009). Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy, Planta Med. 75: 1549–1560.
  • Gazdar, A.F., Girard, L., Lockwood, W.W., Lam, W.L., Minna, J.D. (2010). Lung Cancer Cell Lines as Tools for Biomedical Discovery and, 102: doi:10.1093/jnci/djq279.
  • Gauthier, C., Legault, J., Girard-lalancette, K., Mshvildadze, V., Pichette, A. (2009). Bioorganic & Medicinal Chemistry Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupaneand oleanane-type saponins, Bioorg. Med. Chem. 17: 2002–2008.
  • Liu, B., Zhou, J., Li, Y., Zou, X., Wu, J., Gu, J. et al., (2014). Hederagenin from the leaves of ivy (Hedera helix L .) induces apoptosis in human LoVo colon cells through the mitochondrial pathway, BMC Complement. Altern. Med. 14: 1–10.
  • Kang, K.H., Chae, S., Lee, K.H., Park, M.T., Lee, S.J., Lee, Y.S. et al., (2005). Cytotoxic Effect of 7 β-Hydroxycholesterol on Human NCI-H460 Lung Cancer Cells, Biol. Pharm. Bull. 28: 1377–1380.
  • Allouche, Y., Fernando, W., Campos, M., Sanches-Quesada, C., Uceda, M., Beltran, G. et al. (2011). Antioxidant , Antiproliferative , and Pro-apoptotic Capacities of Pentacyclic Triterpenes Found in the Skin of Olives on MCF-7 Human Breast Cancer Cells and Their Effects on DNA Damage, J. Agric. Food Chem. 59: 121–130.
  • M. Valko, M., Rhodes, C.J., Moncol, J., Izakovic, M., Mazur, M. (2006). Free radicals, metals and antioxidants in oxidative stress-induced cancer, Chem. Biol. Interact. 160: 1–40.
  • Ajiboye, T.O., Komolafe, Y.O.,. Bukoye Oloyede, H.O., Yakubu, M.T., Adeoye, M.D., Abdulsalami, I.O. et al., (2013). Diethylnitrosamine-induced redox imbalance in rat microsomes: protective role of polyphenolic-rich extract from Sorghum bicolor grains, J. Basic Clin. Physiol. Pharmacol. 24: 41–49.
  • Villaño, D., Fernández-Pachón, M.S., Moyá, M.L., Troncoso, A.M., García-Parrilla, M.C. (2007). Radical scavenging ability of polyphenolic compounds towards DPPH free radical, Talanta. 71: 230–235.
  • Mukazayire, M.J., Tomani, J.C., Stevigny, C., Chalchat, J.C., Conforti, F., Menichini, F. et al., (2011). Essential oils of four Rwandese hepatoprotective herbs: Gas chromatography-mass spectrometry analysis and antioxidant activities, Food Chem. 129: 753–760.
  • Dawidowicz, A.L., Wianowska, D., Olszowy, M. (2012). On practical problems in estimation of antioxidant activity of compounds by DPPH method (Problems in estimation of antioxidant activity), Food Chem. 131: 1037–1043.
  • Proestos, C., Lytoudi, K., Mavromelanidou, O., Zoumpoulakis, P., Sinanoglou, V. (2013). Antioxidant Capacity of Selected Plant Extracts and Their Essential Oils, Antioxidants. 2: 11–22.
  • Gul, M.J., Ahmad, F.,. Kondapi, A.K., Qureshi, L.A., Ghazi, L.A. (2013). Antioxidant and antiproliferative activities of Abrus precatorius leaf extracts-an in vitro study., BMC Complement. Altern. Med. 13: 53.
  • Gülçin, I., Mshvildadze, V., Gepdiremen, A., Elias, R. (2006). The Antioxidant Activity of a Triterpenoid Glycoside Isolated from the Berries of Hedera colchica/ : 3-O -(β-D -glucopyranosyl) -hederagenin, 134: 130–134.
  • Wang, S., Fang, W. (2009). Pentacyclic Triterpenoids and their Saponins with ApoptosisInducing Activity, Curr. Top. Med. Chem. 9: 1581–1596.

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