Thyroid stimulating hormone (TSH) autoregulation reduces variation in the TSH response to thyroid hormones

References

• Dietrich JW, Landgrafe G, Fotiadou EH. TSH and thyrotropic agonists: key actors in thyroid homeostasis. J Thyroid Res. 2012;2012:29. Article ID 351864.
   Google Scholar
• Prummel MF, Brokken LJ, Wiersinga WM. Ultra short-loop feedback control of thyrotropin secretion. Thyroid. 2004;14(10):825–829.
   PubMed Web of Science ®Google Scholar
• Kakita T, Labourde NP, Odell WD. Autoregulatory control of thyrotropin in rabbits. Endocrinology. 1984;114(6):2301–2305.
   PubMed Web of Science ®Google Scholar
• Coutifaris C, Hyland L, Chappel SC. Autoregulation of Follicle-stimulating hormone secretion in the Hampster: evidencefor control at the level of the anterior pituitary. Endocrinology. 1984;114:2216.
   PubMed Web of Science ®Google Scholar
• Bentley AM, Wallis M. In-vitro evidence for the autoregulation of prolactin secretion at the level of the pituitary gland in the rat. J Endocrinol. 1987;115:13–18.
   PubMed Web of Science ®Google Scholar
• Boscaro M, Sonino N, Paoletta A, et al. Evidence for ultra-short loop autoregulation of adrenocorticotropin secretion in man. J Clin Endocrinol Metab. 1988;66(2):255–257.
   PubMed Web of Science ®Google Scholar
• Kakita T, Odell WD. Pituitary gland: one site of ultrashort-feedback regulation for control of thyrotropin. Am J Physiol. 1986;250:E121–124.
   PubMed Web of Science ®Google Scholar
• Prummel MF, Brokken LJS, Merduri G, et al. Expression of thyroid-stimulating hormone receptor in the Folliculo-Stellate cells of the human anterior pituitary. J Cin Endocrinol Metab. 2000;85(11):4347–4353.
   PubMed Web of Science ®Google Scholar
• Dietrich JW, Tesche A, Pickardt CR, et al. Thyrotrophic feedback control: evidencefor an additional ultrashort feedback loop from fractal analysis.Cybern Syst. 2004;35:315–331.
   Google Scholar
• Yu H, Farahani P. Thyroid stimulating hormone suppression post-therapy in patients with graves’ disease: a systematic review of pathophysiology and clinical data. Clin Invest Med. 2015;38(1):E31–44.
   PubMed Web of Science ®Google Scholar
• Brokken LJS, Wiersinga WM, Prummel MF. Thyrotrophin Receptor autoantibodies are associated with continued thyrotropin suppression in treated euthyroid Graves’ disease patients. J Clin Endocrinol Metab. 2003;88(9):4135–4138.
   PubMed Web of Science ®Google Scholar
• Benhadi N, Fliers E, Visser TJ, et al. Pilot study on the assessment of the setpoint ofthe hypothalamus-pituitary-thyroid axis in healthy volunteers. Eur J Endocrinol. 2010;162(2):323–329.
   PubMed Web of Science ®Google Scholar
• Fish LH, Schwartz HL, Cavanaugh J, et al. Replacement dose,metabolism and bioavailability of levothyroxine in the treatment of hypothyroidism. N Engl J Med. 1987;316:764–770.
   PubMed Web of Science ®Google Scholar
• Reichlin S, Utiger RD. Regulation of the pituitary-thyroid axis in man: relationship of TSH concentration to concentration of free and total thyroxine in plasma. J ClinEndocr. 1967;27:251–255.
   Web of Science ®Google Scholar
• Hadlow NC, Rothacker KM, Wardrop R, et al. The relationship between TSH and free T4 in a large population is complex and nonlinear anddiffers by age and sex. J Clin Endocrinol Metab. 2013;98(7):2936–2943.
   PubMed Web of Science ®Google Scholar
• Hoermann R, Eckl W, Hoermann C, et al. Complex relationship between free thyroxine and TSH in the regulation of thyroid function. Eur J Endocrinol. 2010;162:1123–1129.
   PubMed Web of Science ®Google Scholar
• Fitzgerald SP, Bean NG. The relationship between population T4/TSH set point data and T4/TSH physiology. J Thyroid Research. 2016;2016:7. Article ID 6351473.
   Web of Science ®Google Scholar
• Kreitschmann-Andremahr I, Hoff C, Saller B, et al. Prevalence of pituitary deficiency in patients after aneurysmal subarachnoid hemorrhage. J Clin Endocrinol Metab. 2004;89(10):4986–4992.
   PubMed Web of Science ®Google Scholar
• Garbutt JC, Mayo JP Jr., Gillette GM, et al. Dose –response studies with thyrotropin-releasing hormone in abstinent male alcoholics: evidence for selective thyrotroph dysfunction? J Stud Alcohol. 1991;52(3):275–280.
   PubMed Web of Science ®Google Scholar
• Castinetti F, Reynaud R, Saveanu A, et al. Clinical and genetic aspects of combined pituitary hormone deficiencies. Ann Endocrinol (Paris). 2008;69(1):7–17.
   PubMed Web of Science ®Google Scholar
• Socin HV, Chanson P, Delemer B, et al. The changing spectrum of TSH- secreting pituitary adenomas: diagnosis and management in 43 patients. Eur J Endocrinol. 2003;148:433–442.
   PubMed Web of Science ®Google Scholar
• Beck- Peccoz P, Persani L, Asteria C, et al. Thyrotropin secreting pituitary tumours in hyper- and hypothyroidism. Acta Med Austriaca. 1996;23(1–2):41–46.
   PubMedGoogle Scholar
• Socin HV, Chanson P, Delemer B, et al. The changing spectrum of TSH-secreting pituitary tumours: diagnosisand management in 43 patients. Eur J Endocrinol. 2003;148:433–442.
   PubMed Web of Science ®Google Scholar
• Andersen S, Pedersen KM, Bruun NH, et al. Narrow individual variations in serum T4 and T3 in normal subjects; A clue to the understanding of subclinical thyroid disease. J Clin Endocrinol Metab. 2002;87:1068–1072.
   PubMed Web of Science ®Google Scholar
• Estrada JM, Soldin D, Buckey TM, et al. Thyrotropin isoforms: implications for thyrotropin analysis and clinical practice. Thyroid. 2014;24(3):411–423.
   PubMed Web of Science ®Google Scholar
• Dumont J, Opitz R, Christophe D, et al. Ontogeny, anatomy, metabolism and physiology of the thyroid. 2015. DeGroot LJ, Beck-Peccoz P, Chroussos G, et al., editors. Endotext [Internet]. MDText.com Inc, cited Jul 15.
   Google Scholar
• Fitzgerald SP, Bean NG, Fitzgerald LN. Population data indicate that thyroid regulation is consistent with an equilibrium-point model, but not with a set point model. Temperature. 2017;4:114–116.
   PubMedGoogle Scholar
• Fitzgerald SP, Bean NG. Population correlations do not support the existence of set points for blood levels of calcium or glucose- a new model for homeostasis. Physiol Rep. 2018;6(1):e13551.
   Web of Science ®Google Scholar
• Modell H, Cliff W, Michael J, et al. A physiologist’s view of homeostasis. Adv Physiol Educ. 2015;39(4):259–266.
   PubMed Web of Science ®Google Scholar