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Molecular & Cellular Oncology Volume 3, 2016 - Issue 1
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Sustaining the spindle assembly checkpoint to improve cancer therapy

Roberta ViscontiCEINGE Biotecnologie Avanzate, Naples, Italy;IEOS, CNR, Naples, Italy
,
Rosa Della MonicaCEINGE Biotecnologie Avanzate, Naples, Italy;DMMBM, University of Naples “Federico II”, Naples, Italy
&
Domenico GriecoCEINGE Biotecnologie Avanzate, Naples, Italy;DMMBM, University of Naples “Federico II”, Naples, ItalyCorrespondence[email protected]
Article: e1046583 | Received 24 Apr 2015, Accepted 25 Apr 2015, Published online: 29 Jan 2016

References

  • Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 2007; 8: 379-93; PMID:17426725; http://dx.doi.org/10.1038/nrm2163
  • Rieder CL, Maiato H. Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint. Dev Cell 2004; 7: 637-51; PMID:15525526; http://dx.doi.org/10.1016/j.devcel.2004.09.002
  • Clarke PA, Allan LA. Destruction's our delight: Controlling apoptosis during mitotic arrest. Cell Cycle 2010; 9:4035-6; PMID:20935484; http://dx.doi.org/10.4161/cc.9.20.13522
  • Topham CH, Taylor SS. Mitosis and apoptosis: how is the balance set? Curr Opin Cell Biol 2013; 25:780-5; PMID:23890995; http://dx.doi.org/10.1016/j.ceb.2013.07.003
  • Huang HC, Shi J, Orth JD, Mitchison TJ. Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell 2009; 16: 347-58; http://dx.doi.org/10.1016/j.ccr.2009.08.020
  • Gascoigne KE, Taylor SS. How do anti-mitotic drugs kill cancer cells? J Cell Sci 2009; 122: 2579-85; PMID:19625502; http://dx.doi.org/10.1242/jcs.039719
  • Visconti R, Palazzo L, Della Monica R, Grieco D. FCP1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit. Nat Commun 2012; 3: 894; PMID:22692537; http://dx.doi.org/10.1038/ncomms1886
  • Visconti R, Della Monica R, Palazzo L, D'Alessio F, Raia M, Improta S, Villa MR, Del Vecchio L, Grieco D. The FCP1-WEE1-CDK1 axis affects spindle assembly checkpoint robustness and sensitivity to antimicrotubule cancer drugs. Cell Death Differ 2015; 22:1551-1560; PMID:25744022; http://dx.doi.org/10.1038/cdd.2015.13
  • D'Angiolella V, Mari C, Nocera D, Rametti L, Grieco D. The spindle checkpoint requires cyclin-dependent kinase activity. Genes Dev 2003;17:2520-5; PMID:14561775; http://dx.doi.org/10.1101/gad.267603
  • Hirai H, Arai T, Okada M, Nishibata T, Kobayashi M, Sakai N, Imagaki K, Ohtani J, Sakai T, Yoshizumi T, et al. MK-1775, a small molecule WEE1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil. Cancer Biol Ther 2010; 9: 514-22; PMID:20107315; http://dx.doi.org/10.4161/cbt.9.7.11115

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