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DDR1 inhibition as a new therapeutic strategy for colorectal cancer

ORCID Icon, ORCID Icon &
Article: e1465882 | Received 11 Apr 2018, Accepted 13 Apr 2018, Published online: 23 Jul 2018

References

  • Vanharanta S, Massagué J. Origins of Metastatic Traits. Cancer Cell. 2013;24(4):410–21. doi:10.1016/j.ccr.2013.09.007.
  • Zhang Z, Wang Y, Zhang J, Zhong J, Yang R. COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway. Mol Med Rep. 2018;17(4):5037–42. doi:10.3892/mmr.2018.8533.
  • Leitinger B. Discoidin domain receptor functions in physiological and pathological conditions. Int Rev Cell Mol Biol. 2014;310:39–87. doi:10.1016/B978-0-12-800180-6.00002-5.
  • Rammal H, Saby C, Magnien K, Van-Gulick L, Garnotel R, Buache E, El Btaouri H, Jeannesson P, Morjani H. Discoidin Domain Receptors: Potential Actors and Targets in Cancer. Front Pharmacol. 2016. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789497/
  • Gao H, Chakraborty G, Zhang Z, Akalay I, Gadiya M, Gao Y, Sinha S, Hu J, Jiang C, Akram M, et al. Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling. Cell. 2016;166(1):47–62. doi:10.1016/j.cell.2016.06.009.
  • Ambrogio C, Nadal E, Villanueva A, Gómez-López G, Cash TP, Barbacid M, Santamaría D. KRAS-driven lung adenocarcinoma: combined DDR1/Notch inhibition as an effective therapy. ESMO Open. 2016. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070278/. doi:10.1136/esmoopen-2016-000076. PMID:27843638
  • Jeitany M, Leroy C, Tosti P, Lafitte M, Guet JL, Simon V, Bonenfant D, Robert B, Grillet F, Mollevi C, et al. Inhibition of DDR1‐BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer. EMBO Mol Med. 2018;10(4): e7918. doi:10.15252/emmm.201707918. PMID:29438985
  • Weisberg E, Manley PW, Breitenstein W, Brüggen J, Cowan-Jacob SW, Ray A, Huntly B, Fabbro D, Fendrich G, Hall-Meyers E, et al. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell. 2005;7(2):129–41. doi:10.1016/j.ccr.2005.01.007.
  • Rix U, Hantschel O, Dürnberger G, Rix LLR, Planyavsky M, Fernbach NV, Kaupe I, Bennett KL, Valent P, Colinge J, et al. Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets. Blood. 2007;110(12):4055–63. doi:10.1182/blood-2007-07-102061.
  • Grillet F, Bayet E, Villeronce O, Zappia L, Lagerqvist EL, Lunke S, Charafe-Jauffret E, Pham K, Molck C, Rolland N, et al. Circulating tumour cells from patients with colorectal cancer have cancer stem cell hallmarks in ex vivo culture. Gut. 2017;66(10):1802–10. doi:10.1136/gutjnl-2016-311447