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Escape from senescence: revisiting cancer therapeutic strategies

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Article: 2030158 | Received 10 Dec 2021, Accepted 07 Jan 2022, Published online: 15 Feb 2022

References

  • Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O, Bishop C, Campisi J, Collado M, Evangelou K, Ferbeyre G et al. Cellular Senescence: Defining a Path Forward. Cell. 2019;179(4):813–3 . PMID:31675495. http://dx.doi.org/10.1016/j.cell.2019.10.005.
  • Halazonetis TD, Gorgoulis VG, Bartek J. An oncogene-induced DNA damage model for cancer development. Science. 2008;319(5868):1352–1355 . PMID:18323444. http://dx.doi.org/10.1126/science.1140735.
  • Komseli ES, Pateras IS, Krejsgaard T, Stawiski K, Rizou SV, Polyzos A, Roumelioti FM, Chiourea M, Mourkioti I, Paparouna E et al. A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence. BMC Genom. 2018;19(1):37 . PMID:29321003. http://dx.doi.org/10.1186/s12864-017-4375-1.
  • Zampetidis CP, Galanos P, Angelopoulou A, Zhu Y, Polyzou A, Karamitros K, Kotsinas A, Lagopati N, Mourkioti I, Mirzazadeh R et al. A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization. Mol Cell. 2021;81(23):4907–4923.e8 . PMID:34793711. http://dx.doi.org/10.1016/j.molcel.2021.10.017.
  • Gaucher J, Montellier E, Sassone-Corsi P. Molecular cogs: interplay between circadian clock and cell cycle. Trends Cell Biol. 2018;28(5):368–379 . PMID:29471986. http://dx.doi.org/10.1016/j.tcb.2018.01.006.
  • Fisher D, Mechali M. Vertebrate HoxB gene expression requires DNA replication. Embo J. 2003;22(14):3737–3748 . PMID:12853488. http://dx.doi.org/10.1093/emboj/cdg352.
  • Ward EM, Germolec D, Kogevinas M, McCormick D, Vermeulen R, Anisimov VN, Aronson KJ, Bhatti P, Cocco P, Costa G et al. IACR Monographs Vol 124 group. Carcinogenicity of night shift work. Lancet Oncol. 2019;20(8):1058–1059 . PMID:31281097. http://dx.doi.org/10.1016/S1470-2045(19)30455-3.
  • Saleh T, Tyutyunyk-Massey L, Gewirtz DA. Tumor cell escape from therapy-induced senescence as a model of disease recurrence after dormancy. Cancer Res. 2019 ;79(6):1044–1046 . PMID:30803994. http://dx.doi.org/10.1158/0008-5472.CAN-18-3437.
  • Myrianthopoulos V, Evangelou K, Vasileiou PVS, Cooks T, Vassilakopoulos TP, Pangalis GA, Kouloukoussa M, Kittas C, Georgakilas AG, Gorgoulis VG. Senescence and senotherapeutics: a new field in cancer therapy. Pharmacol Ther. 2019;193:31–49 . PMID:30121319. http://dx.doi.org/10.1016/j.pharmthera.2018.08.006.
  • Karakasiliotis I, Lagopati N, Evangelou K, Gorgoulis VG. Cellular senescence as a source of SARS-CoV-2 quasispecies. Febs J. 2021 . PMID:34653312. http://dx.doi.org/10.1111/febs.16230.