1,303
Views
1
CrossRef citations to date
0
Altmetric
Original Articles

Inflammation parameters predict fatal outcome in male COVID-19 patients in a low case-fatality area – a population-based registry study

, , , , & ORCID Icon
Pages 558-571 | Received 17 Jan 2022, Accepted 16 Mar 2022, Published online: 30 Mar 2022

References

  • Zhu A, Zhang DZ, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–733.
  • Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708–1720.
  • Peckham H, de Gruijter NM, Raine C, et al. Male sex identified by global COVID-19 Meta-analysis as a risk factor for death and ITU admission. Nat Commun. 2020;11(1):6317.
  • The Sex, Gender and COVID-19 Project. 5050 Global Health. https://globalhealth5050.org/covid19/.
  • Thompson AE, Anisimowicz Y, Miedema B, et al. The influence of gender and other patient characteristics on health care-seeking behaviour: a QUALICOPC study. BMC Fam Pract. 2016;17:38.
  • Reitsma MB, Kendrick PJ, Ababneh E, et al. Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis from the global burden of disease study 2019. Lancet. 2021;397(10292):2337–2360.
  • GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2013; a systematic analysis for the global burden of disease study 2016. Lancet. 2018;392(10152):1015–1035.
  • Bots SH, Peters SAE, Woodward M. Sex differences in coronary heart disease and stroke mortality: a global assessment of the effect of ageing between 1980 and 2010. BMJ Glob Health. 2017;2(2):e000298.
  • Jarva H, Lappalainen M, Luomala O, et al. Laboratory-based surveillance of COVID-19 in the greater helsinki area, Finland, February–June 2020. Int J Infect Dis. 2021;104:111–116.
  • Qin L, Li X, Shi J, et al. Gendered effects on inflammation reaction and outcome of COVID-19 patients in Wuhan. J Med Virol. 2020;92(11):2684–2692.
  • Del Valle DM, Kim-Schulze S, Huang HH, et al. An inflammatory cytokine signature predicts COVID-19 severity and survival. Nat Med. 2020;26(10):1636–1643.
  • Takahashi T, Ellingson MK, Wong P, et al. Yale IMPACT research team. Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature. 2020;588(7837):315–320.
  • Klein SL, Pekosz A, Park HS, et al. Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population. J Clin Invest. 2020;130(11):6141–6150.
  • Robbiani DF, Gaebler C, Muecksch F, et al. Convergent antibody responses to SARS-CoV-2 in convalescent individuals. Nature. 2020;584(7821):437–442.
  • Meng Y, Wu P, Lu W, et al. Sex-specific clinical characteristics and prognosis of coronavirus disease-19 infection in Wuhan, China: a retrospective study of 168 severe patients. PLoS Pathog. 2020;16(4):e1008520.
  • Scully EP, Schumock G, Fu M, et al. Sex and gender differences in testing, hospital admission, clinical presentation, and drivers of severe outcomes from COVID-19. Open Forum Infect Dis. 2021;31;8(9):ofab448.
  • Vahidy FS, Pan AP, Ahnstedt H, et al. Sex differences in susceptibility, severity, and outcomes of coronavirus disease 2019: cross-sectional analysis from a diverse US metropolitan area. PLoS One. 2021;16(1):e0245556.
  • Lau ES, McNeill JN, Paniagua SM, et al. Sex differences in inflammatory markers in patients hospitalized with COVID-19 infection: insights from the MGH COVID-19 patient registry. PLoS One. 2021;16(4):e0250774.
  • Poudel A, Poudel Y, Adhikari A, et al. D-dimer as a biomarker for assessment of COVID-19 prognosis: D-dimer levels on admission and its role in predicting disease outcome in hospitalized patients with COVID-19. PLoS One. 2021;16(8):e0256744.
  • Forsblom E, Silén S, Kortela E, et al. Male predominance in disease severity and mortality in a low Covid-19 epidemic and low case-fatality area – a population-based registry study. Infect Dis (Lond). 2021;53(10):789–799.
  • Bastug A, Bodur H, Erdogan S, et al. Clinical and laboratory features of COVID-19: predictors of severe prognosis. Int Immunopharmacol. 2020;88:106950.
  • Yang AP, Liu JP, Tao WQ, et al. The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients. Int Immunopharmacol. 2020;84:106504.
  • Wang J, Jiang M, Xin Chen X, et al. Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: review of 3939 COVID-19 patients in China and emerging pathogenesis and therapy concepts. J Leukoc Biol. 2020;108(1):17–41.
  • Hu B, Huang S, Yin L. The cytokine storm and COVID-19. J Med Virol. 2021;93(1):250–256.
  • Xu H, Zhong L, Deng J, et al. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Int J Oral Sci. 2020;12(1):8–5.
  • Sun S, Cai X, Wang H, et al. Abnormalities of peripheral blood system in patients with COVID-19 in Wenzhou China. Clin Chim Acta. 2020;507:174–180.
  • Wang F, Hou H, Luo Y, et al. The laboratory tests and host immunity of COVID-19 patients with different severity of illness. JCI Insight. 2020;5(10):e137799.
  • Di Micco P, Russo V, Carannante N, et al. Clotting factors in COVID-19: epidemiological association and prognostic values in different clinical presentations in an Italian cohort. J Clin Med. 2020;9(5):1371.
  • Tang N, Bai H, Chen X, et al. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost. 2020;18(5):1094–1099.
  • Luo HC, You CY, Lu SW, et al. Characteristics of coagulation alteration in patients with COVID-19. Ann Hematol. 2021;100(1):45–52.
  • Peiró ÓM, Carrasquer A, Sánchez-Gimenez R, et al. Biomarkers and short-term prognosis in COVID-19. Biomarkers. 2021;26(2):119–126.
  • Shi S, Nie B, Chen X, et al. Clinical and laboratory characteristics of severe and non-severe patients with COVID-19: a retrospective cohort study in China. Clin Lab Anal. 2021;35(1):e23692.
  • Wang Q, Cheng J, Shang J, et al. Clinical value of laboratory indicators for predicting disease progression and death in patients with COVID-19: a retrospective cohort study. BMJ Open. 2021;1;11(10):e043790.
  • Lv Z, Wang W, Qiao B, et al. The prognostic value of general laboratory testing in patients with COVID-19. J Clin Lab Anal. 2021;35(2):e23668.
  • Zhang L, Yan X, Fan Q, et al. D-dimer levels on admission to predict in-hospital case-fatality in patients with COVID-19. J Thromb Haemost. 2020;18(6):1324–1329.
  • Deng F, Zhang L, Lyu L, et al. Increased levels of ferritin on admission predicts intensive care unit mortality in patients with COVID-19. Med Clin. 2021;156(7):324–331.
  • Zeng Z, Yu H, Chen H, et al. Longitudinal changes of inflammatory parameters and their correlation with disease severity and outcomes in patients with COVID-19 from Wuhan, China. Crit Care. 2020;24(1):525.
  • Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229):1054–1062.
  • Kararigas G. Sex-biased mechanisms of cardiovascular complications in COVID-19. Physiol Rev. 2022;102(1):333–337.
  • Ritter O, Kararigas G. Sex-biased vulnerability of the heart to COVID-19. Mayo Clin Proc. 2020;95(11):2332–2335.
  • Ji HL, Zhao R, Matalon S, et al. Elevated plasmin(ogen) as a common risk factor for COVID-19 susceptibility. Physiol Rev. 2020;100(3):1065–1075.
  • Al-Lami RA, Urban RJ, Volpi E, et al. Sex hormones and novel corona virus infectious disease (COVID-19). Mayo Clin Proc. 2020;95(8):1710–1714.
  • Apicella M, Campopiano MC, Mantuano M, et al. COVID-19 in people with diabetes: understanding the reasons for worse outcomes. Lancet Diabetes Endocrinol. 2020;8(9):782–792.