256
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Obesity in adolescents does not influence early immune responses to influenza vaccination

, , , , , , , & show all
Pages 415-424 | Received 23 Oct 2022, Accepted 21 Mar 2023, Published online: 06 Apr 2023

References

  • Somes MP, Turner RM, Dwyer LJ, et al. Estimating the annual attack rate of seasonal influenza among unvaccinated individuals: a systematic review and meta-analysis. Vaccine. 2018;36(23):3199–3207.
  • Tuckerman J, Misan S, Crawford NW, et al. Influenza in children with special risk medical conditions: a systematic review and meta-analysis. Pediatr Infect Dis J. 2019;38(9):912–919.
  • Eşki A, Öztürk GK, Gülen F, et al. Risk factors for influenza virus related severe lower respiratory tract infection in children. Pediatr Infect Dis J. 2019;38(11):1090–1095.
  • Fezeu L, Julia C, Henegar A, et al. Obesity is associated with higher risk of intensive care unit admission and death in influenza A (H1N1) patients: a systematic review and meta-analysis. Obes Rev. 2011;12(8):653–659.
  • Martin V, Castilla J, Godoy P, et al. High body mass index as a risk factor for hospitalization due to influenza: a case-control study. Arch Bronconeumol. 2016;52:299–307.
  • Garcia MN, Philpott DC, Murray KO, et al. Clinical predictors of disease severity during the 2009-2010 A(HIN1) influenza virus pandemic in a paediatric population. Epidemiol Infect. 2015;143(14):2939–2949.
  • Van Kerkhove MD, Vandemaele KA, Shinde V, et al. Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis. PLoS Med. 2011;8(7):e1001053.
  • Fuhrman C, Bonmarin I, Paty AC, et al. Severe hospitalised 2009 pandemic influenza A(H1N1) cases in France, 1 july-15 november 2009. Euro Surveill. 2010;15(2):19463.
  • Gill PJ, Ashdown HF, Wang K, et al. Identification of children at risk of influenza-related complications in primary and ambulatory care: a systematic review and meta-analysis. Lancet Respir Med. 2015;3(2):139–149.
  • Maier HE, Kuan G, Gresh L, et al. Obesity is associated with increased susceptibility to influenza A (H1N1pdm) but not H3N2 infection. Clin Infect Dis. 2021;73(11):e4345–e52.
  • Garrido-Miguel M, Cavero-Redondo I, Álvarez-Bueno C, et al. Prevalence and trends of overweight and obesity in European children from 1999 to 2016: a systematic review and meta-analysis. JAMA Pediatr. 2019;173(10):e192430-e.
  • Heilsugæsla Höfuðborgarsvæðisins [Primary Care of the Capital Area] Heilsuvernd skólabarna - yfirþyngd og offita 2020-2021 [school children’s health protection - overweight and obesity 2020-2021]. Personal Communication. 2021.
  • Eliakim A, Schwindt C, Zaldivar F, et al. Reduced tetanus antibody titers in overweight children. Autoimmunity. 2006;39(2):137–141.
  • Weber DJ, Rutala WA, Samsa GP, et al. Impaired immunogenicity of hepatitis B vaccine in obese persons. N Engl J Med. 1986;314:1393.
  • Esposito S, Giavoli C, Trombetta C, et al. Immunogenicity, safety and tolerability of inactivated trivalent influenza vaccine in overweight and obese children. Vaccine. 2016;34(1):56–60.
  • Callahan ST, Wolff M, Hill HR, et al. Impact of body mass index on immunogenicity of pandemic H1N1 vaccine in children and adults. J Infect Dis. 2014;210(8):1270–1274.
  • Kainth MK, Fishbein JS, Aydillo T, et al. Obesity and metabolic dysregulation in children provide protective influenza vaccine responses. Viruses. 2022;14(1):124.
  • Cole TJ, Bellizzi MC, Flegal KM, et al. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000;320(7244):1240–1243.
  • Waist Circumference and Waist–Hip Ratio: report of a WHO Expert Consultation; Geneva, 8–11 December 2008. Available from: https://www.who.int/publications/i/item/9789241501491. World Health Organization, 2011.
  • Miller E, Hoschler K, Hardelid P, et al. Incidence of 2009 pandemic influenza a H1N1 infection in England: a cross-sectional serological study. Lancet. 2010;375(9720):1100–1108.
  • Clarke M, Goodchild LM, Evans S, et al. Body mass index and vaccine responses following influenza vaccination during pregnancy. Vaccine. 2021;39(34):4864–4870.
  • Sheridan PA, Paich HA, Handy J, et al. Obesity is associated with impaired immune response to influenza vaccination in humans. Int J Obes. 2012;36(8):1072–1077.
  • Yu X, Tsibane T, McGraw PA, et al. Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature. 2008;455(7212):532–536.
  • Talbot HK, Coleman LA, Crimin K, et al. Association between obesity and vulnerability and serologic response to influenza vaccination in older adults. Vaccine. 2012;30(26):3937–3943.
  • Alhadi MA, Friedman LM, Karlsson EA, et al. Obesity is associated with an altered baseline and post-vaccination influenza antibody repertoire. medRxiv. 2021;2021.03.02.21252785.
  • Ohmit SE, Petrie JG, Cross RT, et al. Influenza hemagglutination-inhibition antibody titer as a correlate of vaccine-induced protection. J Infect Dis. 2011;204(12):1879–1885.
  • Smit MA, Wang HL, Kim E, et al. Influenza vaccine is protective against laboratory-confirmed influenza in obese children. Pediatr Infect Dis J. 2016;35(4):440–445.
  • Neidich SD, Green WD, Rebeles J, et al. Increased risk of influenza among vaccinated adults who are obese. Int J Obes (Lond). 2017;41(9):1324–1330.
  • Piernas C, Patone M, Astbury NM, et al. Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study. Lancet Diabetes Endocrinol. 2022;10(8):571–580.
  • Faizo AA, Qashqari FS, El-Kafrawy SA, et al. A potential association between obesity and reduced effectiveness of COVID-19 vaccine-induced neutralizing humoral immunity. J Med Virol. 2023;95(1):e28130.
  • Paich HA, Sheridan PA, Handy J, et al. Overweight and obese adult humans have a defective cellular immune response to pandemic H1N1 influenza a virus. Obesity. 2013;21(11):2377–2386.
  • Cook IF, Barr I, Hartel G, et al. Reactogenicity and immunogenicity of an inactivated influenza vaccine administered by intramuscular or subcutaneous injection in elderly adults. Vaccine. 2006;24(13):2395–2402.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.