178
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Post-acute midterm follow-up cardiac MRI findings and clinical outcomes in patients with COVID-19 vaccine-associated myocarditis: a comprehensive systematic review and meta-analysis

, , &
Pages 193-205 | Received 03 Aug 2023, Accepted 16 Nov 2023, Published online: 24 Nov 2023

References

  • WHO. Coronavirus disease (COVID-19): herd immunity, lockdowns and COVID-19, WHO. 2021.
  • Haj Mohamad Ebrahim Ketabforoush A, Molaverdi G, Nirouei M, et al. Cerebral venous sinus thrombosis following intracerebral hemorrhage after COVID‐19 AstraZeneca vaccination: a case report. Clin Case Rep. 2022;10(11):e6505. doi:10.1002/ccr3.6505.
  • Shay DK, Shimabukuro TT, DeStefano F. Myocarditis occurring after immunization with mRNA-based COVID-19 vaccines. JAMA Cardiol. 2021;6(10):1115–1117. doi:10.1001/jamacardio.2021.2821.
  • Patone M, Mei XW, Handunnetthi L, et al. Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection. Nat Med. 2022;28(2):410–422. doi:10.1038/s41591-021-01630-0.
  • Samimisedeh P, Sehati F, Afshar EJ. COVID-19 associated fulminant myocarditis in a fully-vaccinated female: a case report with clinical follow-up. Clin Med Insights Case Rep. 2023;16:11795476221147238. doi:10.1177/11795476221147238.
  • Ferreira VM, Schulz-Menger J, Holmvang G, et al. Cardiovascular magnetic resonance in nonischemic myocardial inflammation: expert recommendations. J Am Coll Cardiol. 2018;72(24):3158–3176. doi:10.1016/j.jacc.2018.09.072.
  • Samimisedeh P, Jafari Afshar E, Shafiabadi Hassani N, et al. Cardiac MRI findings in COVID‐19 vaccine‐related myocarditis: a pooled analysis of 468 patients. Magnetic Resonance Imag. 2022;56(4):971–982. doi:10.1002/jmri.28268.
  • Caforio AL, Pankuweit S, Arbustini E, et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the european society of cardiology working group on myocardial and pericardial diseases. Eur Heart J. 2013;34(33):2636–2648. doi:10.1093/eurheartj/eht210.
  • Małek ŁA, Kamińska H, Barczuk‐Falęcka M, et al. Children with acute myocarditis often have persistent subclinical changes as revealed by cardiac magnetic resonance. J Magn Reson Imaging. 2020;52(2):488–496. doi:10.1002/jmri.27036.
  • Law YM, Lal AK, Chen S, et al. Diagnosis and management of myocarditis in children: a scientific statement from the American heart association. Circulation. 2021;144(6):e123–e135. doi:10.1161/CIR.0000000000001001.
  • Camastra G, Ciolina F, Corsi MP, et al. Monitoring the evolution of myocarditis following COVID-19 mRNA vaccination with serial cardiac magnetic resonance imaging. Int J Cardiovasc Imaging. 2022;38(9):2077–2079. doi:10.1007/s10554-022-02603-1.
  • Schauer J, Buddhe S, Gulhane A, et al. Persistent cardiac magnetic resonance imaging findings in a cohort of adolescents with post-coronavirus disease 2019 mRNA vaccine myopericarditis. J Pediatr. 2022;245:233–237. doi:10.1016/j.jpeds.2022.03.032.
  • Corradetti S, Sclafani M, Mistrulli R, et al. Acute myocarditis following covid-19 vaccination: a peculiar case series. Journal of Hypertension. 2022;40(Suppl 1):e174-e. doi:10.1097/01.hjh.0000837152.13471.cf.
  • Dove ML, Slesnick TC, Oster ME, et al. Cardiac magnetic resonance findings of COVID-19 vaccine associated myocarditis at intermediate follow up: a comparison to classic myocarditis and MIS-C related myocarditis. J Pediatr. 2023;11:113462.
  • Fronza M, Thavendiranathan P, Karur GR, et al. Cardiac MRI and clinical follow-up in COVID-19 vaccine–associated myocarditis. Radiology. 2022;304(3):E48–E49. doi:10.1148/radiol.220802.
  • Amir G, Rotstein A, Razon Y, et al. CMR imaging 6 months after myocarditis associated with the BNT162b2 mRNA COVID-19 vaccine. Pediatr Cardiol. 2022;43(7):1522–1529. doi:10.1007/s00246-022-02878-0.
  • Hadley SM, Prakash A, Baker AL, et al. Follow-up cardiac magnetic resonance in children with vaccine-associated myocarditis. Eur J Pediatr. 2022;181(7):2879–2883. doi:10.1007/s00431-022-04482-z.
  • Ahmed T, Chishti E, Sinner GJ, et al. A report on short-term follow-up cardiac imaging and clinical outcomes of myocarditis after coronavirus disease 2019 vaccination. J Cardiovasc Med. 2022;23(10):691–693. doi:10.2459/JCM.0000000000001341.
  • Kracalik I, Oster ME, Broder KR, et al. Outcomes at least 90 days since onset of myocarditis after mRNA COVID-19 vaccination in adolescents and young adults in the USA: a follow-up surveillance study. Lancet Child Adolesc Health. 2022;6(11):788–798. doi:10.1016/S2352-4642(22)00244-9.
  • Patel YR, Shah NR, Lombardi K, et al. Follow-up cardiovascular magnetic resonance findings in patients with COVID-19 vaccination-associated acute myocarditis. Cardiovascular Imag. 2022;15(11):2007–2010.
  • Puchalski M, Kamińska H, Bartoszek M, et al. COVID-19-vaccination-induced myocarditis in teenagers: case series with further follow-up. Int J Environ Res Public Health. 2022;19(6):3456. doi:10.3390/ijerph19063456.
  • Agdamag ACC, Gonzalez D, Carlson K, et al. Fulminant myocarditis following coronavirus disease 2019 vaccination: a case report. Euro Heart J-Case Rep. 2022;6(1):ytac007.
  • Ansari U, Britsch S, Rogowski S, et al. Case report: transient increase of CMR T1 mapping indices in a patient with COVID-19 mRNA vaccine induced acute myocarditis. Front Cardiovasc Med. 2022;9:880717. doi:10.3389/fcvm.2022.880717.
  • Banala KR, Al-Anani S, Anne P, et al. Outcome of post-Covid vaccination myocarditis in an adolescent male. Clin Pediatr (Phila). 2022;62(2):162–165. doi:10.1177/00099228221116207.
  • Cavalcante J, Shaw KE, Gössl M. Cardiac magnetic resonance imaging midterm follow up of COVID-19 vaccine–associated myocarditis. Cardiovascular Imag. 2022;15(10):1821–1824.
  • Gomes DA, Santos RR, Freitas P, et al. Acute myocarditis following mRNA COVID-19 vaccine. Arq Bras Cardiol. 2022;118(4):783–786. doi:10.36660/abc.20210469.
  • Hirsch VG, Schallhorn S, Zwadlo C, et al. Giant cell myocarditis after first dose of BNT162b2–a case report. Eur J Heart Fail. 2022;24(7):1319–1322. doi:10.1002/ejhf.2590.
  • Kawauchi H, Mitsuhashi Y, Nakamura S, et al. Course of cardiac magnetic resonance imaging findings in acute myocarditis after COVID-19 mRNA vaccination. Intern Med. 2022;61(17):2625–2629. doi:10.2169/internalmedicine.9797-22.
  • Konno A, Osada Y, Watanabe K, et al. A case of coronavirus disease 2019 vaccine‐related myocarditis with late gadolinium enhancement on cardiac magnetic resonance imaging persisting over acute phase. Pediatr Int. 2022;64(1):291. doi:10.1111/ped.15291.
  • Korosoglou G, Nunninger P, Giusca S. Case report: disappearance of late gadolinium enhancement and full functional recovery in a young patient with SARS-CoV-2 vaccine-related myocarditis. Front Cardiovasc Med. 2022;9:852931. doi:10.3389/fcvm.2022.852931.
  • Manfredi R, Bianco F, Bucciarelli V, et al. Clinical profiles and CMR findings of young adults and pediatrics with acute myocarditis following mRNA COVID-19 vaccination: a case series. Vaccines. 2022;10(2):169. doi:10.3390/vaccines10020169.
  • Shiyovich A, Plakht Y, Witberg G, et al. Myocarditis following COVID-19 vaccination: a follow-up magnetic resonance imaging study. Cardiovascular Imag. 2022;15(11):2006–2007.
  • Rosner CM, Atkins M, Saeed IM, et al. Patients with myocarditis associated with COVID-19 vaccination. J Am Coll Cardiol. 2022;79(13):1317–1319. doi:10.1016/j.jacc.2022.02.004.
  • Eichhorn C, Greulich S, Bucciarelli-Ducci C, et al. Multiparametric cardiovascular magnetic resonance approach in diagnosing, monitoring, and prognostication of myocarditis. JACC: cardiovascular Imag. 2022;15(7):1325–1338. doi:10.1016/j.jcmg.2021.11.017.
  • Munn Z, Barker TH, Moola S, et al. Methodological quality of case series studies: an introduction to the JBI critical appraisal tool. JBI Evid Synthe. 2020;18(10):2127–2133.
  • Ahmad S, Yuson C, Le A, et al. Myopericarditis following both BNT162b2 and NVX-CoV2373. Allergy Asthma Clin Immunol. 2022;18(1):109. doi:10.1186/s13223-022-00750-7.
  • Corradetti S, Sclafani M, Mistrulli R, et al. Features and follow-up of patients affected by noninflammatory myocarditis after coronavirus disease 2019 vaccination. J Cardiovasc Med. 2023;24(1):65–68. doi:10.2459/JCM.0000000000001385.
  • Kravchenko D, Isaak A, Mesropyan N, et al. Cardiac magnetic resonance follow-up of COVID-19 vaccine associated acute myocarditis. Front Cardiovasc Med. 2022;9:1049256. doi:10.3389/fcvm.2022.1049256.
  • Cerqueira MD, Weissman NJ, Dilsizian V, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the cardiac imaging committee of the council on clinical cardiology of the American heart association. Circulation. 2002;105(4):539–542. doi:10.1161/hc0402.102975.
  • Berg J, Kottwitz J, Baltensperger N, et al. Cardiac magnetic resonance imaging in myocarditis reveals persistent disease activity despite normalization of cardiac enzymes and inflammatory parameters at 3-month follow-up. Circ: heart Failure. 2017;10(11):e004262. doi:10.1161/CIRCHEARTFAILURE.117.004262.
  • Sanchez Tijmes F, Thavendiranathan P, Udell JA, et al. Cardiac MRI assessment of nonischemic myocardial inflammation: state of the art review and update on myocarditis associated with COVID-19 vaccination. Radiol Cardiothorac Imag. 2021;3(6):e210252. doi:10.1148/ryct.210252.
  • Dubey S, Agarwal A, Nguyen S, et al. Persistence of late gadolinium enhancement on follow-up CMR imaging in children with acute myocarditis. Pediatr Cardiol. 2020;41(8):1777–1782. doi:10.1007/s00246-020-02445-5.
  • Olimulder M, Van Es J, Galjee M. The importance of cardiac MRI as a diagnostic tool in viral myocarditis-induced cardiomyopathy. Neth Heart J. 2009;17(12):481–486. doi:10.1007/BF03086308.
  • Li DL, Davogustto G, Soslow JH, et al. Characteristics of COVID-19 myocarditis with and without multisystem inflammatory syndrome. Am J Cardiol. 2022;168:135–141. doi:10.1016/j.amjcard.2021.12.031.
  • Mahrholdt H, Wagner A, Deluigi CC, et al. Presentation, patterns of myocardial damage, and clinical course of viral myocarditis. Circulation. 2006;114(15):1581–1590. doi:10.1161/CIRCULATIONAHA.105.606509.
  • Spartalis M, Tzatzaki E, Spartalis E, et al. Parvovirus B19 myocarditis of fulminant evolution. Cardiol Res. 2017;8(4):172–175. doi:10.14740/cr580w.
  • Aquaro GD, Ghebru Habtemicael Y, Camastra G, et al. Prognostic value of repeating cardiac magnetic resonance in patients with acute myocarditis. J Am Coll Cardiol. 2019;74(20):2439–2448. doi:10.1016/j.jacc.2019.08.1061.
  • Schnell F, Claessen G, La Gerche A, et al. Subepicardial delayed gadolinium enhancement in asymptomatic athletes: Let sleeping dogs lie? Br J Sports Med. 2016;50(2):111–117. doi:10.1136/bjsports-2014-094546.
  • Fung G, Luo H, Qiu Y, et al. Myocarditis. Circ Res. 2016;118(3):496–514. doi:10.1161/CIRCRESAHA.115.306573.
  • Ghelani SJ, Spaeder MC, Pastor W, et al. Demographics, trends, and outcomes in pediatric acute myocarditis in the United States, 2006 to 2011. Circ Cardiovasc Qual Outcomes. 2012;5(5):622–627. doi:10.1161/CIRCOUTCOMES.112.965749.
  • Pelliccia A, Solberg EE, Papadakis M, et al. Recommendations for participation in competitive and leisure time sport in athletes with cardiomyopathies, myocarditis, and pericarditis: position statement of the sport cardiology section of the European association of preventive cardiology (EAPC). Eur Heart J. 2019;40(1):19–33. doi:10.1093/eurheartj/ehy730.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.