176
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Genotypic cluster analysis of Neisseria gonorrhoeae reveals a spectrum of sexual mixing including among HIV-serodiscordant men who have sex with men

ORCID Icon, , , , , , , , , , & ORCID Icon show all
Received 03 Aug 2023, Accepted 01 Apr 2024, Published online: 22 Jun 2024

References

  • World Health Organization. Report on global sexually transmitted infection surveillance. Geneva: WHO; 2018.
  • World Health Organization. Global health sector strategies on, respectively, HIV, viral hepatitis and sexually transmitted infections for the period 2022–2030. Geneva: WHO; 2022.
  • Ong JJ, Baggaley RC, Wi TE, et al. Global epidemiologic characteristics of sexually transmitted infections among individuals using preexposure prophylaxis for the prevention of HIV infection: a systematic review and meta-analysis. JAMA Netw Open. 2019;2(12):e1917134. doi: 10.1001/jamanetworkopen.2019.17134.
  • European Centre for Disease Prevention and Control (ECDC). Annual epidemiological report for 2019. Stockholm; 2023.
  • European Centre for Disease Prevention and Control (ECDC). Gonorrhoea. Annual epidemiological report for 2018. Stockholm; 2020.
  • Workowski KA, Bachmann LH, Chan PA, et al. Sexually transmitted infections treatment guidelines, 2021. MMWR Recomm Rep. 2021;70(4):1–187. doi: 10.15585/mmwr.rr7004a1.
  • Traeger MW, Cornelisse VJ, Asselin J, et al. Association of HIV preexposure prophylaxis with incidence of sexually transmitted infections among individuals at high risk of HIV infection. JAMA. 2019;321(14):1380–1390. doi: 10.1001/jama.2019.2947.
  • Chromy D, Urban N, Grabmeier-Pfistershammer K, et al. High prevalence of asymptomatic sexually transmitted infections in Austrian pre-exposure prophylaxis users: a prospective observational study. AIDS Patient Care STDS. 2023;37(3):115–118. doi: 10.1089/apc.2022.0154.
  • Chromy D, Bauer DJM, Simbrunner B, et al. The 'Viennese epidemic’ of acute HCV in the era of direct-acting antivirals. J Viral Hepat. 2022;29(5):385–394. doi: 10.1111/jvh.13665.
  • Vaughan AM, Cenciarelli O, Colombe S, et al. A large multi-country outbreak of monkeypox across 41 countries in the WHO European region, 7 March to 23 August 2022. Euro Surveill. 2022;27(36):2200620. doi: 10.2807/1560-7917.Es.2022.27.36.2200620.
  • Baggaley RF, White RG, Boily MC. HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV prevention. Int J Epidemiol. 2010;39(4):1048–1063. doi: 10.1093/ije/dyq057.
  • Ring A, Balakrishna S, Imkamp F, et al. High rates of asymptomatic Mycoplasma genitalium infections with high proportion of genotypic resistance to first-line macrolide treatment among men who have sex with men enrolled in the Zurich primary HIV infection study. Open Forum Infect Dis. 2022;9(6):ofac217. doi: 10.1093/ofid/ofac217.
  • European Centre for Disease Prevention and Control (ECDC). Gonococcal antimicrobial susceptibility surveillance in the EU/EEA: summary of results for 2019. Stockholm: ECDC; 2021.
  • Orbe-Orihuela YC, Sánchez-Alemán M, Hernández-Pliego A, et al. Syphilis as re-emerging disease, antibiotic resistance, and vulnerable population: global systematic review and meta-analysis. Pathogens. 2022;11(12):1546. doi: 10.3390/pathogens11121546.
  • Moreno-Mingorance A, Mir-Cros A, Goterris L, et al. Increasing trend of antimicrobial resistance in Shigella associated with MSM transmission in Barcelona, 2020–21: outbreak of XRD Shigella sonnei and dissemination of ESBL-producing Shigella flexneri. J Antimicrob Chemother. 2023;78(4):975–982. doi: 10.1093/jac/dkad031.
  • Skaletz-Rorowski A, Potthoff A, Nambiar S, et al. Sexual behaviour, STI knowledge and Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) prevalence in an asymptomatic cohort in Ruhr-area, Germany: PreYoungGo study. J Eur Acad Dermatol Venereol. 2021;35(1):241–246. doi: 10.1111/jdv.16913.
  • Geusau A, Chromy D, Heissenberger D, et al. Resistance profiles of Neisseria gonorrhoeae isolates in Vienna, Austria: a phenotypic and genetic characterization from 2013 to 2020. Int J Antimicrob Agents. 2022;60(5–6):106656. doi: 10.1016/j.ijantimicag.2022.106656.
  • Schaeffer J, Lippert K, Pleininger S, et al. Association of phylogenomic relatedness among Neisseria gonorrhoeae strains with antimicrobial resistance, Austria, 2016–2020. Emerg Infect Dis. 2022;28(8):1694–1698. doi: 10.3201/eid2808.220071.
  • Harrison OB, Cehovin A, Skett J, et al. Neisseria gonorrhoeae population genomics: use of the gonococcal core genome to improve surveillance of antimicrobial resistance. J Infect Dis. 2020;222(11):1816–1825. doi: 10.1093/infdis/jiaa002.
  • Peters J, Cresswell F, Amor L, et al. Whole genome sequencing of Neisseria gonorrhoeae reveals transmission clusters involving patients of mixed HIV serostatus. Sex Transm Infect. 2018;94(2):138–143. doi: 10.1136/sextrans-2017-053198.
  • Town K, Field N, Harris SR, et al. Phylogenomic analysis of Neisseria gonorrhoeae transmission to assess sexual mixing and HIV transmission risk in England: a cross-sectional, observational, whole-genome sequencing study. Lancet Infect Dis. 2020;20(4):478–486. doi: 10.1016/s1473-3099(19)30610-3.
  • Williamson DA, Chow EPF, Gorrie CL, et al. Bridging of Neisseria gonorrhoeae lineages across sexual networks in the HIV pre-exposure prophylaxis era. Nat Commun. 2019;10(1):3988. doi: 10.1038/s41467-019-12053-4.
  • Hosseini-Hooshyar S, Martinello M, Yee J, et al. Low hepatitis C virus reinfection rate despite ongoing risk following universal access to direct-acting antiviral therapy among people living with HIV. AIDS. 2020;34(9):1347–1358. doi: 10.1097/qad.0000000000002562.
  • Garvey LJ, Cooke GS, Smith C, et al. Decline in hepatitis C virus (HCV) incidence in men who have sex with men living with human immunodeficiency virus: progress to HCV microelimination in the United Kingdom? Clin Infect Dis. 2021;72(2):233–238. doi: 10.1093/cid/ciaa021.
  • Marquez LK, Ingiliz P, Boesecke C, et al. Establishing a framework towards monitoring HCV microelimination among men who have sex with men living with HIV in Germany: a modeling analysis. PLOS One. 2022;17(5):e0267853. doi: 10.1371/journal.pone.0267853.
  • Chromy D, Bauer D, Simbrunner B, et al. Progress of hepatitis C elimination in Viennese people living with HIV after two decades of increasing cure rates. Infect Dis. 2022;55(3):189–198. doi: 10.1080/23744235.2022.2153914.
  • Jones J, Le Guillou A, Gift TL, et al. Effect of screening and treatment for gonorrhea and chlamydia on HIV incidence among men who have sex with men in the United States: a modeling analysis. Sex Transm Dis. 2022;49(10):669–676. doi: 10.1097/olq.0000000000001685.
  • Mao L, Kippax SC, Holt M, et al. Rates of condom and non-condom-based anal intercourse practices among homosexually active men in Australia: deliberate HIV risk reduction? Sex Transm Infect. 2011;87(6):489–493. doi: 10.1136/sextrans-2011-050041.
  • Ward H, Rönn M. Contribution of sexually transmitted infections to the sexual transmission of HIV. Curr Opin HIV AIDS. 2010;5(4):305–310. doi: 10.1097/COH.0b013e32833a8844.
  • Leierer G, Rappold M, Strickner S, et al. 42th report of the Austrian HIV cohort study; 2022.
  • Rodger AJ, Cambiano V, Bruun T, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet. 2019;393(10189):2428–2438. doi: 10.1016/s0140-6736(19)30418-0.
  • Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587–2599. doi: 10.1056/NEJMoa1011205.
  • Thigpen MC, Kebaabetswe PM, Paxton LA, et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med. 2012;367(5):423–434. doi: 10.1056/NEJMoa1110711.
  • Jones J, Weiss K, Mermin J, et al. Proportion of incident human immunodeficiency virus cases among men who have sex with men attributable to gonorrhea and chlamydia: a modeling analysis. Sex Transm Dis. 2019;46(6):357–363. doi: 10.1097/olq.0000000000000980.
  • Molina JM, Ghosn J, Assoumou L, et al. Daily and on-demand HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil (ANRS PREVENIR): a prospective observational cohort study. Lancet HIV. 2022;9(8):e554–e562. doi: 10.1016/s2352-3018(22)00133-3.
  • Basten M, den Daas C, Heijne JCM, et al. The rhythm of risk: sexual behaviour, PrEP use and HIV risk perception between 1999 and 2018 among men who have sex with men in Amsterdam, The Netherlands. AIDS Behav. 2020;25(6):1800–1809. doi: 10.1007/s10461-020-03109-4.
  • EACS guidelines version 11.0; 2021.
  • Berçot B, Charreau I, Clotilde R, et al. High prevalence and high rate of antibiotic resistance of Mycoplasma genitalium infections in men who have sex with men. A sub-study of the ANRS Ipergay PrEP trial. Clin Infect Dis. 2020;73(7):e2127–e2133. doi: 10.1093/cid/ciaa1832.
  • Johnson Jones ML, Chapin-Bardales J, Bizune D, et al. Extragenital chlamydia and gonorrhea among community venue-attending men who have sex with men – five cities, United States, 2017. MMWR Morb Mortal Wkly Rep. 2019;68(14):321–325. doi: 10.15585/mmwr.mm6814a1.
  • van Liere G, Hoebe C, Dirks JA, et al. Spontaneous clearance of urogenital, anorectal and oropharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae in women, MSM and heterosexual men visiting the STI clinic: a prospective cohort study. Sex Transm Infect. 2019;95(7):505–510. doi: 10.1136/sextrans-2018-053825.
  • Chow EPF, Vodstrcil LA, Williamson DA, et al. Incidence and duration of incident oropharyngeal gonorrhoea and chlamydia infections among men who have sex with men: prospective cohort study. Sex Transm Infect. 2021;97(6):452–457. doi: 10.1136/sextrans-2020-054764.