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Mitochondrial DNA Part A
DNA Mapping, Sequencing, and Analysis
Volume 29, 2018 - Issue 6
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Research Article

Complete hydatidiform moles are composed of paternal chromosomes and maternal mitochondria

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Pages 943-950 | Received 08 Jul 2017, Accepted 12 Sep 2017, Published online: 17 Oct 2017

References

  • Azuma C, Saji F, Tokugawa Y, Kimura T, Nobunaga T, Takemura M, Kameda T, Tanizawa O. 1991. Application of gene amplification by polymerase chain reaction to genetic analysis of molar mitochondrial DNA: the detection of anuclear empty ovum as the cause of complete mole. Gynecol Oncol. 40:29–33.
  • Baasanjav B, Usui H, Kihara M, Kaku H, Nakada E, Tate S, Mitsuhashi A, Matsui H, Shozu M. 2010. The risk of post-molar gestational trophoblastic neoplasia is higher in heterozygous than in homozygous complete hydatidiform moles. Hum Reprod. 25:1183–1191.
  • Bendall KE, Sykes BC. 1995. Length heteroplasmy in the first hypervariable segment of the human mtDNA control region. Am J Hum Genet. 57:248–256.
  • Brown GG, Gadaleta G, Pepe G, Saccone C, Sbisa E. 1986. Structural conservation and variation in the D-loop-containing region of vertebrate mitochondrial DNA. J Mol Biol. 192:503–511.
  • Budowle B, Allard MW, Wilson MR, Chakraborty R. 2003. Forensics and mitochondrial DNA: applications, debates, and foundations. Annu Rev Genomics Hum Genet. 4:119–141.
  • Burgstaller JP, Johnston IG, Poulton J. 2015. Mitochondrial DNA disease and developmental implications for reproductive strategies. Mol Hum Reprod. 21:11–22.
  • Edwards YH, Jeremiah SJ, McMillan SL, Povey S, Fisher RA, Lawler SD. 1984. Complete hydatidiform moles combine maternal mitochondria with a paternal nuclear genome. Ann Hum Genet. 48:119–127.
  • Egger J, Wilson J. 1983. Mitochondrial inheritance in a mitochondrially mediated disease. N Engl J Med. 309:142–146.
  • Giles RE, Blanc H, Cann HM, Wallace DC. 1980. Maternal inheritance of human mitochondrial DNA. Proc Natl Acad Sci USA. 77:6715–6719.
  • Golubovsky MD. 2003. Postzygotic diploidization of triploids as a source of unusual cases of mosaicism, chimerism and twinning. Hum Reprod. 18:236–242.
  • Horai S, Hayasaka K. 1990. Intraspecific nucleotide sequence differences in the major noncoding region of human mitochondrial DNA. Am J Hum Genet. 46:828–842.
  • Kajii T, Ohama K. 1977. Androgenetic origin of hydatidiform mole. Nature. 268:633–634.
  • Lurain JR. 2010. Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. Am J Obstet Gynecol. 203:531–539.
  • Mabuchi T, Susukida R, Kido A, Oya M. 2007. Typing the 1.1 kb control region of human mitochondrial DNA in Japanese individuals. J Forensic Sci. 52:355–363.
  • Ohama K, Ueda K, Okamoto E, Takenaka M, Fujiwara A. 1986. Cytogenetic and clinicopathologic studies of partial moles. Obstet Gynecol. 68:259–262.
  • Schwartz M, Vissing J. 2002. Paternal inheritance of mitochondrial DNA. N Engl J Med. 347:576–580.
  • Seckl MJ, Sebire NJ, Berkowitz RS. 2010. Gestational trophoblastic disease. Lancet. 376:717–729.
  • Tie J, Wang X, Oxida S. 2006. Genetic polymorphisms of 15 STR loci in a Japanese population. J Forensic Sci. 51:188–189.
  • Usui H, Kiyokawa T, Qu J, Nishikimi K, Tate S, Mitsuhashi A, Nakatani Y, Shozu M. 2016. Comparison between pathological diagnosis and cytogenetic diagnosis by short tandem repeat polymorphism analysis of suspected molar pregnancies. J Reprod Med. 61:219–223.
  • Vassilakos P, Riotton G, Kajii T. 1977. Hydatidiform mole: two entities. A morphologic and cytogenetic study with some clinical consideration. Am J Obstet Gynecol. 127:167–170.
  • Wallace DC, Surti U, Adams CW, Szulman AE. 1982. Complete moles have paternal chromosomes but maternal mitochondrial DNA. Hum Genet. 61:145–147.
  • Wallace DC, Zheng XX, Lott MT, Shoffner JM, Hodge JA, Kelley RI, Epstein CM, Hopkins LC. 1988. Familial mitochondrial encephalomyopathy (MERRF): genetic, pathophysiological, and biochemical characterization of a mitochondrial DNA disease. Cell. 55:601–610.
  • Zeviani M, Servidei S, Gellera C, Bertini E, DiMauro S, DiDonato S. 1989. An autosomal dominant disorder with multiple deletions of mitochondrial DNA starting at the D-loop region. Nature. 339:309–311.

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