A Systematic Review of Stimulant Use in Civilian and Military Aviation

References

• Akerstedt, T. (2000). Consensus statement: Fatigue and accidents in transport operations. Journal of Sleep Research, 9(4), 395. https://doi.org/10.1046/j.1365-2869.2000.00228.x
   PubMed Web of Science ®Google Scholar
• Åkerstedt, T., & Landström, U. (1998). Work place countermeasures of night shift fatigue. International Journal of Industrial Ergonomics, 21(3–4), 167–178. https://doi.org/10.1016/s0169-8141(97)00045-0
   Web of Science ®Google Scholar
• Amann, U., Holmes, A., Caldwell, J., & Hilditch, C. (2014). Sleep and sleepiness of pilots operating long-range airplane emergency medical missions. Aviation, Space, and Environmental Medicine, 85(9), 954–959. https://doi.org/10.3357/asem.3986.2014
   Google Scholar
• Belland, K. M., & Bissell, C. (1994). A subjective study of fatigue during Navy flight operations over southern Iraq: Operation southern watch. Aviation, Space, and Environmental Medicine, 65(6), 557–561.
   Google Scholar
• Bendak, S., & Rashid, H. S. (2020). Fatigue in aviation: A systematic review of the literature. International Journal of Industrial Ergonomics, 76, 102928. https://doi.org/10.1016/j.ergon.2020.102928
   Web of Science ®Google Scholar
• Caldwell, J. A. (2005). Dextroamphetamine and modafinil are effective countermeasures for fatigue in the operational environment. Strategies to Maintain Combat Readiness during Extended Deployments – A Human Systems Approach (pp. 31-1 – 31-16). Meeting Proceedings RTO-MP-HFM-124, Paper 31. Neuilly-sur-Seine. RTO. http://www.rto.nato.int/abstracts.asp
   Google Scholar
• Caldwell, J. A. (2008). Go pills in combat: Prejudice, propriety, and practicality. Airpower Journal, 22(3), 97–101.
   Google Scholar
• Caldwell, J. A., & Gilreath, S. R. (2002). A survey of aircrew fatigue in a sample of U.S. Army aviation personnel. Aviation, Space, and Environmental Medicine, 73(5), 473–480.
   Google Scholar
• Caldwell, J. A., Mallis, M. M., Caldwell, J. L., Paul, M. A., Miller, J. C., & Neri, D. F. (2009). Fatigue countermeasures in aviation. Aviation, Space, and Environmental Medicine, 80(1), 29–59. https://doi.org/10.3357/asem.2435.2009
   PubMedGoogle Scholar
• Caldwell, J. L., Chandler, J. F., & Hartzler, B. M. (2012). Battling fatigue in aviation: Recent advancements in research and practice. Journal of Medical Sciences, 32(2), 47–56. https://doi.org/10.6136/JMS.2012.32(2).047
   Google Scholar
• Caska, T. J., & Molesworth, B. R. (2007). The effects of low dose caffeine on pilot performance. International Journal of Applied Aviation Studies, 7(2), 244–255.
   Google Scholar
• Cornum, K., Cornum, R., & Storm, W. (1996). Use of psychostimulants in extended flight operations: A desert shield experiment. Conference proceeding from the Neurological Limitations of Aircraft Operations Conference for the Advisory Group for Aerospace Research and Development (AGARD).
   Google Scholar
• Dinges, D. F., Graeber, R. C., Connell, L. J., Rosekind, M. R., & Powell, J. W. (1990). Fatigue-related reaction time performance in long-haul flight crews. Sleep Research, 19, 117.
   Google Scholar
• Doan, B. K., Hickey, P. A., Lieberman, H. R., & Fischer, J. R. (2006). Caffeinated tube food effect on pilot performance during a 9-hour, simulated nighttime U-2 mission. Aviation, Space, and Environmental Medicine, 77(10), 1034–1040.
   PubMedGoogle Scholar
• Dungan, C. P. (2004). Rules of engagement and fratricide prevention: Lessons from the Tarnak farms incident. UCLA Journal of International Law & Foreign Affairs, 9, 301. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=612021
   Google Scholar
• Emonson, D. L., & Vanderbeek, R. D. (1995). The use of amphetamines in U.S. air force tactical operations during desert shield and storm. Aviation, Space, and Environmental Medicine, 66(3), 260–263.
   Google Scholar
• Federal Aviation Administration. (2020, March 12). Fatigue Risk Management: Frequently Asked Questions. https://www.faa.gov/about/initiatives/maintenance_hf/fatigue/faq/#q45
   Google Scholar
• Gaines, A. R., Morris, M. B., & Gunzelmann, G. (2020). Fatigue-related aviation mishaps. Aerospace Medicine and Human Performance, 91(5), 440–447. https://doi.org/10.3357/amhp.5515.2020
   Web of Science ®Google Scholar
• Gander, P. H., Barnes, R. M., Gregory, K. B., Graeber, R. C., Connell, L. J., & Rosekind, M. R. (1998a). Flight crew fatigue III: North Sea helicopter air transport operations. Aviation Space and Environmental Medicine, 69(9), B16–B25.
   Google Scholar
• Gander, P. H., Graeber, R. C., Foushee, H. C., Lauber, J. K., & Connell, L. J. (1994). Crew factors in flight operations 2: Psychophysiological responses to short-haul air transport operations (Report No. 108856). National Aeronautics and Space Administration, Ames Research Center.
   Google Scholar
• Gander, P. H., Gregory, K. B., Graeber, R. C., Connell, L. J., Miller, D. L., & Rosekind, M. R. (1998b). Flight crew fatigue II: Short-haul fixed-wing air transport operations. Aviation, Space, and Environmental Medicine, 69(9, Sect 2), B8–B15.
   Google Scholar
• Gander, P. H., Gregory, K. B., Graeber, R. C., Connell, L. J., Miller, D. L., & Rosekind, M. R. (1998c). Flight crew fatigue IV: Overnight cargo operations. Aviation, Space, and Environmental Medicine, 69(9, Sect 2), B26–B36.
   Google Scholar
• Gander, P. H., Gregory, K. B., Graeber, R. C., Connell, L. J., Miller, D. L., & Rosekind, M. R. (1998d). Flight crew fatigue V: Long-haul air transport operations. Aviation, Space, and Environmental Medicine, 69(9, Sect 2), B37–B48.
   Google Scholar
• Gander, P. H., Rosekind, M. R., & Gregory, K. B. (1998e). Flight crew fatigue VI: A synthesis. Aviation Space and Environmental Medicine, 69(9), B49–B60.
   Google Scholar
• Gore, R. K., Webb, T. S., & Hermes, E. D. (2010). Fatigue and stimulant use in military fighter aircrew during combat operations. Aviation, Space and Environmental Medicine, 81(8), 719–727. https://doi.org/10.3357/asem.2755.2010
   Google Scholar
• Gregory, K. B., Winn, W., Johnson, K., & Rosekind, M. R. (2010). Pilot fatigue survey: Exploring fatigue factors in air medical operations. Air Medical Journal, 29(6), 309–319. https://doi.org/10.1016/j.amj.2010.07.002
   PubMedGoogle Scholar
• Hobbs, A. N., Gregory, K. B., Parke, B. K., Pradhan, S. K., Caddick, Z., Bathurst, N. G., & Flynn-Evans, E. E. (2018). San Francisco bar pilot fatigue study (Report No. NASA/TM—2018–219934.). National Aeronautics and Space Administration.
   Google Scholar
• Hurst, P. M. (1962). The effects of d-amphetamine on risk taking. Psychopharmacologia, 3(4), 283–290. https://doi.org/10.1007/BF00411368
   Google Scholar
• Karacan, I., Thornby, J. I., Anch, A. M., Booth, G. H., Williams, R. L., & Salis, P. J. (1976). Dose‐related sleep disturbances induced by coffee and caffeine. Clinical Pharmacology & Therapeutics, 20(6), 682–689. https://doi.org/10.1002/cpt1976206682
   PubMed Web of Science ®Google Scholar
• Kelley, A. M., Feltman, K. A., & Curry, I. P. (2018). A survey of fatigue in Army aviators. Aerospace Medicine and Human Performance, 89(5), 464–468. https://doi.org/10.3357/AMHP.5044.2018
   Web of Science ®Google Scholar
• Kenagy, D. N., Bird, C. T., Webber, C. M., & Fischer, J. R. (2004). Dextroamphetamine use during B-2 combat missions. Aviation, Space, and Environmental Medicine, 75(5), 381–386.
   Google Scholar
• Kilpeläinen, A. A., Huttunen, K. H., Lohi, J. J., & Lyytinen, H. (2010). Effect of caffeine on vigilance and cognitive performance during extended wakefulness. The International Journal of Aviation Psychology, 20(2), 144–159. https://doi.org/10.1080/10508411003617847
   Web of Science ®Google Scholar
• Latorella, K. A., & Prabhu, P. V. (2000). A review of human error in aviation maintenance and inspection. International Journal of Industrial Ergonomics, 26(2), 133–161. https://doi.org/10.1016/S0169-8141(99)00063-3
   Web of Science ®Google Scholar
• Lohi, J. J., Huttunen, K. H., Lahtinen, T. M., Kilpeläinen, A. A., Muhli, A. A., & Leino, T. K. (2007). Effect of caffeine on simulator flight performance in sleep-deprived military pilot students. Military Medicine, 172(9), 982–987. https://doi.org/10.7205/milmed.172.9.982
   Web of Science ®Google Scholar
• Marcus, J. H., & Rosekind, M. R. (2017). Fatigue in transportation: NTSB investigations and safety recommendations. Injury Prevention, 23(4), 232–238. https://doi.org/10.1136/injuryprev-2015-041791
   Web of Science ®Google Scholar
• McLellan, T. M., Caldwell, J. A., & Lieberman, H. R. (2016). A review of caffeine’s effects on cognitive, physical and occupational performance. Neuroscience & Biobehavioral Reviews, 71, 294–312. https://doi.org/10.1016/j.neubiorev.2016.09.001
   PubMed Web of Science ®Google Scholar
• Meadows, A. B. (2005). Fatigue in continuous and sustained airpower operations: review of pharmacologic countermeasures and policy recommendations. Air Command And Staff College Air University.
   Google Scholar
• Miller, J. C., & Melfi, M. L. (2006). Causes and effects of fatigue in experienced military aircrew (Report No. AFRL-HE-BR-TR271). Human Effectiveness Directorate Brooks Air Force Base Fatigue Countermeasures Branch.
   Google Scholar
• Mills, K. C., Spruill, S. E., Kanne, R. W., Parkman, K. M., & Zhang, Y. (2001). The influence of stimulants, sedatives, and fatigue on tunnel vision: Risk factors for driving and piloting. Human Factors, 43(2), 310–327. https://doi.org/10.1518/001872001775900878
   PubMed Web of Science ®Google Scholar
• Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., … Stewart, L. A. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Systematic Reviews, 4(1), 1. https://doi.org/10.1186/2046-4053–4-1
   PubMed Web of Science ®Google Scholar
• National Aeronautics and Space Administration. (1981). Pilot fatigue and circadian desynchronosis (Report of a workshop held in San Francisco, CA, on August 26-28, 1980; Technical Memorandum 81275). NASA-Ames Research Center.
   Google Scholar
• Ooi, T., Wong, S. H., & See, B. (2019). Modafinil as a stimulant for military aviators. Aerospace Medicine and Human Performance, 90(5), 480–483. https://doi.org/10.3357/AMHP.5298.2019
   PubMed Web of Science ®Google Scholar
• Petrilli, R. M., Thomas, M. J., Dawson, D., & Roach, G. D. (2006). The decision-making of commercial airline crews following an international pattern. Proceedings of the Seventh International AAvPA Symposium (pp. 9–12). Sydney, Australia.
   Google Scholar
• Rosekind, M. R., Co, E. L., Gregory, K. B., & Miller, D. L. (2000a). Crew factors in flight operations XIII: A survey of fatigue factors in corporate/executive aviation operations (Report No. NASA/TM-2000-209). National Aeronautics and Space Administration, Ames Research Center.
   Google Scholar
• Rosekind, M. R., Gregory, K. B., Co, E. L., Miller, D. L., & Dinges, D. F. (2000b). Crew factors in flight operations XII: A survey of sleep quantity and quality in on-board crew rest facilities (Report No. NASA/TM-2000-209611). National Aeronautics and Space Administration, Ames Research Center.
   Google Scholar
• Rosenberg, E., & Caine, Y. (2001). Survey of Israeli Air Force line commander support for fatigue prevention initiatives. Aviation, Space, and Environmental Medicine, 72(4), 352–356.
   Google Scholar
• Sallinen, M., Sihvola, M., Puttonen, S., Ketola, K., Tuori, A., Härmä, M., … Åkerstedt, T. (2017). Sleep, alertness and alertness management among commercial airline pilots on short-haul and long-haul flights. Accident Analysis & Prevention, 98, 320–329. https://doi.org/10.1016/j.aap.2016.10.029
   Web of Science ®Google Scholar
• Samel, A., Wegmann, H. M., & Vejvoda, M. (1995). Jet lag and sleepiness in aircrew. Journal of Sleep Research, 4, 30–36. https://doi.org/10.1111/j.1365-2869.1995.tb00223.x
   PubMed Web of Science ®Google Scholar
• Schultz, D., & Miller, J. C. (2004). Fatigue and use of go/no-go pills in extraordinarily long combat sorties. Aviation, Space, and Environmental Medicine, 75(4), 370–371.
   Google Scholar
• Stephens, M. B., Attipoe, S., Jones, D., Ledford, C. J., & Deuster, P. A. (2014). Energy drink and energy shot use in the military. Nutrition Reviews, 72(suppl 1), 72–77. https://doi.org/10.1111/nure.12139
   Google Scholar
• Van Dongen, H. P., & Dinges, D. F. (2000). Circadian rhythms in fatigue, alertness, and performance. In M. H. Kryger, T. Roth, & W. C. Dement (Eds.), Principles and practice of sleep medicine (3rd ed., pp. 391–399). Philadelphia, PA: W. B. Saunders.
   Google Scholar
• Williamson, A., Lombardi, D. A., Folkard, S., Stutts, J., Courtney, T. K., & Connor, J. L. (2011). The link between fatigue and safety. Accident Analysis & Prevention, 43(2), 498–515. https://doi.org/10.1016/j.aap.2009.11.011
   PubMed Web of Science ®Google Scholar
• Yang, A., Palmer, A. A., & de Wit, H. (2010). Genetics of caffeine consumption and responses to caffeine. Psychopharmacology, 211(3), 245–257. https://doi.org/10.1007/s00213-010-1900-1
   Web of Science ®Google Scholar