4,658
Views
0
CrossRef citations to date
0
Altmetric
Case Reports

Long acting insulin glargine overdose, a surprising long lifetime

ORCID Icon, , , , , & ORCID Icon show all

References

  • Stapczynski JS, Haskell RJ. Duration of hypoglycemia and need for intravenous glucose following intentional overdoses of insulin. Ann Emerg Med. 1984;13:505–511.
  • Arem R, Zoghbi W. Insulin overdose in eight patients: insulin pharmacokinetics and review of the literature. Medicine (Baltimore). 1985;64:323–332.
  • Lucidi P, Porcellati F, Candeloro P, et al. Glargine metabolism over 24 h following its subcutaneous injection in patients with type 2 diabetes mellitus: a dose–response study. Nutr Metab Cardiovasc Dis. 2014;24:709–716.
  • Mégarbane B, Deye N, Bloch V, et al. Intentional overdose with insulin: prognostic factors and toxicokinetic/toxicodynamic profiles. Crit Care. 2007;11:R115.
  • Lu M, Inboriboon PC. Lantus Insulin Overdose: a Case Report. J Emerg Med. 2011;41:374–377.
  • Mork TA, Killeen CT, Patel NK, et al. Massive insulin overdose managed by monitoring daily insulin levels. Am J Ther. 2011;18:e162–e166.
  • Kumar A, Hayes CE, Iwashyna SJ, et al. Management of intentional overdose of insulin glargine. Endocrinol Nutr. 2012;59:570–572.
  • Canning J, O’Connor A, Truitt C. Prolonged, refractory hypoglycemia after insulin glargine overdose treated with continuous D50 infusion and confirmed with insulin and C-peptide levels. North Am Congr Clin Toxicol. 2010;48:657.
  • Brvar M, Mozina M, Bunc M. Poisoning with insulin glargine. Clin Toxicol (Phila).. 2005;43:219–220.
  • Kuhn B, Cantrell L. Unintentional overdose of insulin glargine. Am J Health Syst Pharm. 2008;65:508.
  • Kim CCK, Rosano TG, Chambers EE, et al. Insulin glargine and insulin aspart overdose with pharmacokinetic analysis. AACE Clin Case Rep. 2016;2:e122–e128.
  • Fromont I, Benhaim D, Ottomani A, et al. Prolonged glucose requirements after intentional glargine and aspart overdose. Diabetes Metab. 2007;33:390–392.
  • Tofade TS, Liles EA. Intentional overdose with insulin glargine and insulin aspart. Pharmacotherapy. 2004;24:1412–1418.
  • Karatas F, Sahin S, Karatas H, et al. The highest (3600 IU) reported overdose of insulin glargine ever and management. Indian J Crit Care Med. 2015;19:750.
  • Fuller ET, Miller MA, Kaylor DW, et al. Lantus overdose: case presentation and management options. J Emerg Med.. 2009;36:26–29.
  • Doğan FS, Onur OE, Altınok AD, et al. Insulin glargine overdose. J Pharmacol Pharmacother. 2012;3:333.
  • Groth CM, Banzon ER. Octreotide for the treatment of hypoglycemia after insulin glargine overdose. J Emerg Med. 2013;45:194–198.
  • Ashawesh K, Padinjakara RNK, Murthy NP, et al. Intentional overdose with insulin glargine. Am J Health Syst Pharm. 2009;66:534.
  • Thornton S, Gutovitz S. Intravenous overdose of insulin glargine without prolonged hypoglycemic effects. J Emerg Med. 2012;43:435–437.
  • Moore DF, Wood DF, Volans GN. Features, prevention and management of acute overdose due to antidiabetic drugs. Drug Saf. 1993;9:218–229.