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Toxicology Communications Volume 6, 2022 - Issue 1
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Case Report

Treatment of acute aluminum toxicity due to alum bladder irrigation in a hemodialysis patient: a case report

David Loughrana Rutgers New Jersey Medical School, Department of Medical Toxicology, Newark, NJ, USACorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-5151-4234
ORCID Icon,
Diane Calellob Rutgers New Jersey Medical School, Department of Medical Toxicology, New Jersey Poison Information and Education System, Newark, NJ, USAORCID Iconhttps://orcid.org/0000-0003-1752-847X
ORCID Icon &
Lewis Nelsona Rutgers New Jersey Medical School, Department of Medical Toxicology, Newark, NJ, USAORCID Iconhttps://orcid.org/0000-0001-9551-3922
ORCID Icon
Pages 35-38 | Published online: 27 Feb 2022

References

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  • Igbokwe IO, Igwenagu E, Igbokwe NA. Aluminium toxicosis: a review of toxic actions and effects. Interdiscip Toxicol. 2019;12(2):45–70. Epub 2020 Feb 20. PMID: 32206026; PMCID: PMC7071840.
  • Nakamura H, Rose PG, Blumer JL, et al. Acute encephalopathy due to aluminum toxicity successfully treated by combined intravenous deferoxamine and hemodialysis. J Clin Pharmacol. 2000;40(3):296–300. PMID: 10709159.
  • Han S, Lemire J, Appanna VP, et al. How aluminum, an intracellular ROS generator promotes hepatic and neurological diseases: the metabolic tale. Cell Biol Toxicol. 2013;29(2):75–84. Epub 2013 Mar 6. PMID: 23463459.
  • Mailloux RJ, Hamel R, Appanna VD. Aluminum toxicity elicits a dysfunctional TCA cycle and succinate accumulation in hepatocytes. J Biochem Mol Toxicol. 2006;20(4):198–208. PMID: 16906525.
  • Alfrey AC, LeGendre GR, Kaehny WD. The dialysis encephalopathy syndrome. Possible aluminum intoxication. N Engl J Med. 1976;294(4):184–188. PMID: 1244532.
  • Phelps KR, Naylor K, Brien TP, et al. Encephalopathy after bladder irrigation with alum: case report and literature review. Am J Med Sci. 1999;318(3):181–185. PMID: 10487408.
  • Ackrill P, Ralston AJ, Day JP, et al. Successful removal of aluminium from patient with dialysis encephalopathy. The Lancet. 1980;316(8196):692–693.

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