Publication Cover
Structural Heart
The Journal of the Heart Team
Volume 5, 2021 - Issue 4
70
Views
0
CrossRef citations to date
0
Altmetric
Review Article

Frailty Assessment of Transcatheter Aortic Valve Replacement Patients: Contemporary Practice and Future Directions

, MD, MMedORCID Icon, , MD, PhD, , MD, , MDORCID Icon, , MD, PhD, , MBChB, BPharm, , MD, , MD & , MBChB, MPH show all
Pages 357-366 | Received 03 Dec 2020, Accepted 19 Apr 2021, Published online: 22 Jun 2021

References

  • Mylotte D, Osnabrugge RLJ, Windecker S, et al. Transcatheter aortic valve replacement in Europe: adoption trends and factors influencing device utilization. J Am Coll Cardiol. 2013;62(3):210–219. doi:10.1016/j.jacc.2013.03.074.
  • Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med. 2011;364(23):2187–2198. doi:10.1056/NEJMoa1103510.
  • Leon MB, Smith CR, Mack MJ, et al. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2016;374(17):1609–1620. doi:10.1056/NEJMoa1514616.
  • Mack MJ, Leon MB, Thourani VH, et al. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients. N Engl J Med. 2019;380(18):1695–1705. doi:10.1056/NEJMoa1814052.
  • Adams DH, Popma JJ, Reardon MJ, et al. Transcatheter aortic-valve replacement with a self-expanding prosthesis. N Engl J Med. 2014;370(19):1790–1798. doi:10.1056/NEJMoa1400590.
  • Reardon MJ, Van Mieghem NM, Popma JJ, et al. Surgical or transcatheter aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2017;376(14):1321–1331. doi:10.1056/NEJMoa1700456.
  • Popma JJ, Deeb GM, Yakubov SJ, et al. Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients. N Engl J Med. 2019;380(18):1706–1715. doi:10.1056/NEJMoa1816885.
  • Anand A, Harley C, Visvanathan A, et al. The relationship between preoperative frailty and outcomes following transcatheter aortic valve implantation: a systematic review and meta-analysis. Eur Heart J Qual Care Clin Outcomes. 2017;3(2):123–132. doi:10.1093/ehjqcco/qcw030.
  • Afilalo J, Lauck S, Kim DH, et al. Frailty in older adults undergoing aortic valve replacement: the FRAILTY-AVR study. J Am Coll Cardiol. 2017;70(6):689–700. doi:10.1016/j.jacc.2017.06.024.
  • Shimura T, Yamamoto M, Kano S, et al. Impact of frailty markers on outcomes after transcatheter aortic valve replacement: insights from a Japanese multicenter registry. Ann Cardiothorac Surg. 2017;6(5):532–537. doi:10.21037/acs.2017.09.06.
  • Green P, Arnold SV, Cohen DJ, et al. Relation of frailty to outcomes after transcatheter aortic valve replacement (from the PARTNER trial). Am J Cardiol. 2015;116(2):264–269. doi:10.1016/j.amjcard.2015.03.061.
  • Huang L, Zhou X, Yang X, Yu H. The impact of preoperative frailty status on outcomes after transcatheter aortic valve replacement: an update of systematic review and meta-analysis. Medicine (Baltimore). 2018;97(51):e13475. doi:10.1097/MD.0000000000013475.
  • Shimura T, Yamamoto M, Kano S, et al. Impact of the clinical frailty scale on outcomes after transcatheter aortic valve replacement. Circulation. 2017;135(21):2013–2024. doi:10.1161/CIRCULATIONAHA.116.025630.
  • Kiani S, Stebbins A, Thourani VH, et al. The effect and relationship of frailty indices on survival after transcatheter aortic valve replacement. JACC Cardiovasc Interv. 2020;13(2):219–231. doi:10.1016/j.jcin.2019.08.015.
  • Bendayan M, Messas N, Perrault LP, et al. Frailty and bleeding in older adults undergoing TAVR or SAVR: insights from the FRAILTY-AVR study. JACC Cardiovasc Interv. 2020;13(9):1058–1068. doi:10.1016/j.jcin.2020.01.238.
  • Nishimura RA, Otto CM, Bonow RO, et al. 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American college of cardiology/american heart association task force on clinical practice guidelines. J Am Coll Cardiol. 2017;70(2):252–289.
  • Asgar AW, Ouzounian M, Adams C, et al. 2019 Canadian cardiovascular society position statement for transcatheter aortic valve implantation. Can J Cardiol. 2019;35(11):1437–1448. doi:10.1016/j.cjca.2019.08.011.
  • Baumgartner H, Falk V, Bax JJ, et al. 2017 ESC/EACTS guidelines for the management of valvular heart disease. Rev Esp Cardiol (Engl Ed). 2018;71(2):110.
  • Rodriguez-Manas L, Feart C, Mann G, et al. Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. J Gerontol A Biol Sci Med Sci. 2013;68(1):62–67. doi:10.1093/gerona/gls119.
  • Dent E, Morley JE, Cruz-Jentoft AJ, et al. Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management. J Nutr Health Aging. 2019;23(9):771–787.
  • Dent E, Lien C, Lim WS, et al. The Asia-pacific clinical practice guidelines for the management of frailty. J Am Med Dir Assoc. 2017;18(7):564–575.
  • Green P, Russo M, Arnold S, et al. TCT-36 frailty in intermediate risk patients undergoing transcatheter or surgical aortic valve replacement, cut points and relationship with outcomes: an analysis of the Placement of Aortic Transcatheter Valves (PARTNER) 2 cohort a randomized trial. J Am Coll Cardiol. 2016;68(18_Supplement):B15–B. doi:10.1016/j.jacc.2016.09.058.
  • Tran DTT, Tu JV, Dupuis JY, Eddeen AB, Sun LY. Association of frailty and long‐term survival in patients undergoing coronary artery bypass grafting. J Am Heart Assoc. 2018;7(15):e009882. doi:10.1161/JAHA.118.009882.
  • Afilalo J, Karunananthan S, Eisenberg MJ, Alexander KP, Bergman H. Role of frailty in patients with cardiovascular disease. Am J Cardiol. 2009;103(11):1616–1621. doi:10.1016/j.amjcard.2009.01.375.
  • Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146–56. doi:10.1093/gerona/56.3.M146.
  • Fukui S, Kawakami M, Otaka Y, et al. Physical frailty in older people with severe aortic stenosis. Aging Clin Exp Res. 2016;28(6):1081–1087. doi:10.1007/s40520-015-0507-0.
  • Steyerberg EW, Vickers AJ, Cook NR, et al. Assessing the performance of prediction models: a framework for traditional and novel measures. Epidemiology. 2010;21(1):128–138. doi:10.1097/EDE.0b013e3181c30fb2.
  • Dent E, Kowal P, Hoogendijk EO. Frailty measurement in research and clinical practice: a review. Eur J Intern Med. 2016;31:3–10. doi:10.1016/j.ejim.2016.03.007.
  • De Vries NM, Staal JB, Van Ravensberg CD, Hobbelen JS, Olde Rikkert MG. Nijhuis-van der Sanden MW. Outcome instruments to measure frailty: a systematic review. Ageing Res Rev. 2011;10(1):104–114. doi:10.1016/j.arr.2010.09.001.
  • Guralnik JM, Ferrucci L, Simonsick EM, Salive ME, Wallace RB. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med. 1995;332(9):556–562. doi:10.1056/NEJM199503023320902.
  • Pighi M, Piazza N, Martucci G, et al. Sex-specific determinants of outcomes after transcatheter aortic valve replacement. Circ Cardiovasc Qual Outcomes. 2019;12(3):e005363. doi:10.1161/CIRCOUTCOMES.118.005363.
  • Green P, Woglom AE, Genereux P, et al. The impact of frailty status on survival after transcatheter aortic valve replacement in older adults with severe aortic stenosis: a single-center experience. JACC Cardiovasc Interv. 2012;5(9):974–981. doi:10.1016/j.jcin.2012.06.011.
  • Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005;173(5):489–495. doi:10.1503/cmaj.050051.
  • Ekerstad N, Swahn E, Janzon M, et al. Frailty is independently associated with short-term outcomes for elderly patients with non-ST-segment elevation myocardial infarction. Circulation. 2011;124(22):2397–2404. doi:10.1161/CIRCULATIONAHA.111.025452.
  • Gregorevic KJ, Hubbard RE, Lim WK, Katz B. The clinical frailty scale predicts functional decline and mortality when used by junior medical staff: a prospective cohort study. BMC Geriatr. 2016;16(1):117. doi:10.1186/s12877-016-0292-4.
  • Schoenenberger AW, Stortecky S, Neumann S, et al. Predictors of functional decline in elderly patients undergoing transcatheter aortic valve implantation (TAVI). Eur Heart J. 2013;34(9):684–692. doi:10.1093/eurheartj/ehs304.
  • Schoenenberger AW, Moser A, Bertschi D, et al. Improvement of risk prediction after transcatheter aortic valve replacement by combining frailty with conventional risk scores. JACC Cardiovasc Interv. 2018;11(4):395–403. doi:10.1016/j.jcin.2017.11.012.
  • Skaar E, Eide LSP, Norekval TM, et al. A novel geriatric assessment frailty score predicts 2-year mortality after transcatheter aortic valve implantation. Eur Heart J Qual Care Clin Outcomes. 2019;5(2):153–160. doi:10.1093/ehjqcco/qcy044.
  • Lauck SB, Sathananthan J, Park J, et al. Post-procedure protocol to facilitate next-day discharge: results of the multidisciplinary, multimodality but minimalist TAVR study. Catheter Cardiovasc Interv. 2020;96(2):450–458. doi:10.1002/ccd.28617.
  • Wood DA, Lauck SB, Cairns JA, et al. The Vancouver 3M (Multidisciplinary, Multimodality, But Minimalist) clinical pathway facilitates safe next-day discharge home at low-, medium-, and high-volume transfemoral transcatheter aortic valve replacement centers: the 3M TAVR study. JACC Cardiovasc Interv. 2019;12(5):459–469. doi:10.1016/j.jcin.2018.12.020.
  • Sathananthan J, Webb JG, Polderman J, et al. Safety of accelerated recovery on a cardiology ward and early discharge following minimalist TAVR in the catheterization laboratory: the vancouver accelerated recovery clinical pathway. Struct Heart. 2019;3(3):229–235. doi:10.1080/24748706.2019.1592268.
  • Sathananthan J, Lauck S, Cairns J, et al. TCT-225 Impact of frailty on a minimalist approach and early discharge following TAVR: insights from the 3M TAVR study. J Am Coll Cardiol. 2018;72(13):B94–B. doi:10.1016/j.jacc.2018.08.1348.
  • Kortebein P, Symons TB, Ferrando A, et al. Functional impact of 10 days of bed rest in healthy older adults. J Gerontol A Biol Sci Med Sci. 2008;63(10):1076–1081. doi:10.1093/gerona/63.10.1076.
  • Kortebein P, Ferrando A, Lombeida J, Wolfe R, Evans WJ. Effect of 10 days of bed rest on skeletal muscle in healthy older adults. JAMA. 2007;297(16):1772–1774. doi:10.1001/jama.297.16.1772-b.
  • Eide LS, Ranhoff AH, Fridlund B, et al. Comparison of frequency, risk factors, and time course of postoperative delirium in octogenarians after transcatheter aortic valve implantation versus surgical aortic valve replacement. Am J Cardiol. 2015;115(6):802–809. doi:10.1016/j.amjcard.2014.12.043.
  • Wood DA. Could a “Simplified” transcatheter aortic valve replacement procedure eliminate post-operative delirium? JACC Cardiovasc Interv. 2016;9(2):169–170. doi:10.1016/j.jcin.2015.12.002.
  • Barbanti M, Van Mourik MS, Spence MS, et al. Optimising patient discharge management after transfemoral transcatheter aortic valve implantation: the multicentre European FAST-TAVI trial. EuroIntervention. 2019;15(2):147–154. doi:10.4244/EIJ-D-18-01197.
  • Babaliaros V, Devireddy C, Lerakis S, et al. Comparison of transfemoral transcatheter aortic valve replacement performed in the catheterization laboratory (minimalist approach) versus hybrid operating room (standard approach): outcomes and cost analysis. JACC Cardiovasc Interv. 2014;7(8):898–904. doi:10.1016/j.jcin.2014.04.005.
  • Attizzani GF, Alkhalil A, Padaliya B, et al. Comparison of outcomes of transfemoral transcatheter aortic valve implantation using a minimally invasive versus conventional strategy. Am J Cardiol. 2015;116(11):1731–1736. doi:10.1016/j.amjcard.2015.08.044.
  • Kamioka N, Wells J, Keegan P, et al. Predictors and clinical outcomes of next-day discharge after minimalist transfemoral transcatheter aortic valve replacement. JACC Cardiovasc Interv. 2018;11(2):107–115. doi:10.1016/j.jcin.2017.10.021.
  • Chopra M, Luk NHV, De Backer O, Sondergaard L. Simplification and optimization of transcatheter aortic valve implantation - fast-track course without compromising safety and efficacy. BMC Cardiovasc Disord. 2018;18(1):231. doi:10.1186/s12872-018-0976-0.
  • Hosoba S, Yamamoto M, Shioda K, et al. Safety and efficacy of minimalist approach in transfemoral transcatheter aortic valve replacement: insights from the Optimized transCathEter vAlvular interventioN-Transcatheter Aortic Valve Implantation (OCEAN-TAVI) registry. Interact Cardiovasc Thorac Surg. 2018;26(3):420–424. doi:10.1093/icvts/ivx355.
  • Greif M, Lange P, Nabauer M, et al. Transcutaneous aortic valve replacement with the Edwards SAPIEN XT and Medtronic CoreValve prosthesis under fluoroscopic guidance and local anaesthesia only. Heart. 2014;100(9):691–695. doi:10.1136/heartjnl-2013-304918.
  • Durand E, Borz B, Godin M, et al. Transfemoral aortic valve replacement with the Edwards SAPIEN and Edwards SAPIEN XT prosthesis using exclusively local anesthesia and fluoroscopic guidance: feasibility and 30-day outcomes. JACC Cardiovasc Interv. 2012;5(5):461–467. doi:10.1016/j.jcin.2012.01.018.
  • Yamamoto M, Meguro K, Mouillet G, et al. Effect of local anesthetic management with conscious sedation in patients undergoing transcatheter aortic valve implantation. Am J Cardiol. 2013;111(1):94–99. doi:10.1016/j.amjcard.2012.08.053.
  • Lauck SB, Gibson JA, Baumbusch J, et al. Transition to palliative care when transcatheter aortic valve implantation is not an option: opportunities and recommendations. Curr Opin Support Palliat Care. 2016;10(1):18–23. doi:10.1097/SPC.0000000000000180.
  • Coylewright M, O’Neill E, Sherman A, et al. The learning curve for shared decision-making in symptomatic aortic stenosis. JAMA Cardiol. 2020;5(4):442. doi:10.1001/jamacardio.2019.5719.
  • Bibas L, Levi M, Bendayan M, Mullie L, Forman DE, Afilalo J. Therapeutic interventions for frail elderly patients: part I. Published randomized trials. Prog Cardiovasc Dis. 2014;57(2):134–143. doi:10.1016/j.pcad.2014.07.004.
  • Oka RK, De Marco T, Haskell WL, et al. Impact of a home-based walking and resistance training program on quality of life in patients with heart failure. Am J Cardiol. 2000;85(3):365–369. doi:10.1016/S0002-9149(99)00748-1.
  • Cooper LB, Mentz RJ, Sun J-L, et al. Psychosocial factors, exercise adherence, and outcomes in heart failure patients: insights from Heart Failure: a Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION). Circulation. 2015;8(6):1044–1051. doi:10.1161/CIRCHEARTFAILURE.115.002327.
  • Scalvini S, Zanelli E, Comini L, et al. Home-based versus in-hospital cardiac rehabilitation after cardiac surgery: a nonrandomized controlled study. Phys Ther. 2013;93(8):1073–1083. doi:10.2522/ptj.20120212.
  • Moholdt T, Bekken Vold M, Grimsmo J, Slørdahl SA, Wisløff U. Home-based aerobic interval training improves peak oxygen uptake equal to residential cardiac rehabilitation: a randomized, controlled trial. PLoS One. 2012;7(7):e41199. doi:10.1371/journal.pone.0041199.
  • Russo N, Compostella L, Tarantini G, et al. Cardiac rehabilitation after transcatheter versus surgical prosthetic valve implantation for aortic stenosis in the elderly. Eur J Prev Cardiol. 2014;21(11):1341–1348. doi:10.1177/2047487313494029.
  • Zanettini R, Gatto G, Mori I, et al. Cardiac rehabilitation and mid-term follow-up after transcatheter aortic valve implantation. J Geriatr Cardiol. 2014;11(4):279–285. doi:10.11909/j..1671-5411.2014.04.001.
  • Abizanda P, López MD, García VP, et al. Effects of an oral nutritional supplementation plus physical exercise intervention on the physical function, nutritional status, and quality of life in frail institutionalized older adults: the ACTIVNES study. J Am Med Dir Assoc. 2015;16(5):439.e9-.e16. doi:10.1016/j.jamda.2015.02.005.
  • Kim HK, Suzuki T, Saito K, et al. Effects of exercise and amino acid supplementation on body composition and physical function in community-dwelling elderly Japanese sarcopenic women: a randomized controlled trial. J Am Geriatr Soc. 2012;60(1):16–23. doi:10.1111/j.1532-5415.2011.03776.x.
  • Habaybeh D, De Moraes MB, Slee A, Avgerinou C. Nutritional interventions for heart failure patients who are malnourished or at risk of malnutrition or cachexia: a systematic review and meta-analysis. Heart Fail Rev. 2020. doi:10.1007/s10741-020-09937-9.
  • Driggin E, Madhavan MV, Bikdeli B, et al. Cardiovascular considerations for patients, health care workers, and health systems during the COVID-19 pandemic. J Am Coll Cardiol. 2020;75(18):2352–2371. doi:10.1016/j.jacc.2020.03.031.
  • Lauck S, Forman J, Borregaard B, et al. Facilitating transcatheter aortic valve implantation in the era of COVID-19: recommendations for programmes. Eur J Cardiovasc Nurs. 2020;19(6):537–544. doi:10.1177/1474515120934057.
  • Kruse CS, Soma M, Pulluri D, Nemali NT, Brooks M. The effectiveness of telemedicine in the management of chronic heart disease - a systematic review. JRSM Open. 2017;8(3):2054270416681747. doi:10.1177/2054270416681747.
  • Fraysse JL, Delavillemarque N, Gasparutto B, et al. [Home telemonitoring of CPAP: a feasibility study]. Rev Mal Respir. 2012;29(1):60–63. doi:10.1016/j.rmr.2011.10.009.
  • Young LB, Foster L, Silander A, Wakefield BJ. Home telehealth: patient satisfaction, program functions, and challenges for the care coordinator. J Gerontol Nurs. 2011;37(11):38–46. doi:10.3928/00989134-20110706-02.
  • Snoswell CL, Caffery LJ, Haydon HM, Wickramasinghe SI, Crumblin K, Smith AC. A cost-consequence analysis comparing patient travel, outreach, and telehealth clinic models for a specialist diabetes service to Indigenous people in Queensland. J Telemed Telecare. 2019;25(9):537–544. doi:10.1177/1357633X19873239.
  • Poppas A, Rumsfeld JS, Wessler JD. Telehealth Is Having a Moment: will it Last? J Am Coll Cardiol. 2020;75(23):2989–2991. doi:10.1016/j.jacc.2020.05.002.
  • Malmstrom TK, Morley JE. Sarcopenia: the Target Population. J Frailty Aging. 2013;2(1):55–56. doi:10.14283/jfa.2013.8.
  • Malmstrom TK, Morley JE. SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. J Am Med Dir Assoc. 2013;14(8):531–532. doi:10.1016/j.jamda.2013.05.018.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.