5,273
Views
3
CrossRef citations to date
0
Altmetric
Review Articles

Clinical use of anti-histone antibodies in idiopathic and drug-induced lupus

ORCID Icon
Pages 180-185 | Received 23 Oct 2021, Accepted 28 Mar 2022, Published online: 06 Apr 2022

References

  • Burlingame RW. The clinical utility of antihistone antibodies. Autoantibodies reactive with chromatin in systemic lupus erythematosus and drug-induced lupus. Clin Lab Med. 1997;17(3):367–378.
  • McGinty RK, Tan S. Nucleosome structure and function. Chem Rev. 2015;115(6):2255–2273.
  • Prado F, Jimeno-González S, Reyes JC. Histone availability as a strategy to control gene expression. RNA Biol. 2017;14(3):281–286.
  • Marzluff WF, Gongidi P, Woods KR, et al. The human and mouse replication-dependent histone genes. Genomics. 2002;80(5):487–498.
  • Liu CL, Tangsombatvisit S, Rosenberg JM, et al. Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. Arthritis Res Ther. 2012;14(1):R25.
  • Janssen KMJ, de Smit MJ, Withaar C, et al. Autoantibodies against citrullinated histone H3 in rheumatoid arthritis and periodontitis patients. J Clin Periodontol. 2017;44(6):577–584.
  • Muller S, Dieker J, Tincani A, et al. Pathogenic anti-nucleosome antibodies. Lupus. 2008;17(5):431–436.
  • Hayashi-Takanaka Y, Maehara K, Harada A, et al. Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies. Chromosome Res. 2015;23(4):753–766.
  • Khan MA, Alam K, Hassan SM, et al. Nitration of H2B histone elicits an immune response in experimental animals. Autoimmunity. 2017;50(4):232–240.
  • Vieson MD, Gojmerac AM, Khan D, et al. Treatment with a selective histone deacetylase 6 inhibitor decreases lupus nephritis in NZB/W mice. Histol Histopathol. 2017;32(12):1317–1332.
  • Waibel M, Christiansen AJ, Hibbs ML, et al. Manipulation of B-cell responses with histone deacetylase inhibitors. Nat Commun. 2015;6(1):6838.
  • Kawai C, Kotani H, Miyao M, et al. Circulating extracellular histones are clinically relevant mediators of multiple organ injury. Am J Pathol. 2016;186(4):829–843.
  • Stummvoll GH, Fritsch RD, Meyer B, et al. Characterisation of cellular and humoral autoimmune responses to histone H1 and core histones in human systemic lupus erythaematosus. Ann Rheum Dis. 2009;68(1):110–116.
  • Voll RE, Roth EA, Girkontaite I, et al. Histone-specific Th0 and Th1 clones derived from systemic lupus erythematosus patients induce double-stranded DNA antibody production. Arthritis Rheum. 1997;40(12):2162–2171.
  • Lee AYS, Ang EBH. A clinical overview of autoantibodies in general practice rheumatology. Br J Gen Pract. 2014;64(626):e599.
  • Krippner H, Springer B, Merle S, et al. Antibodies to histones of the IgG and IgM class in systemic lupus erythematosus. Clin Exp Immunol. 1984;58(1):49–56.
  • Cornett EM, Dickson BM, Rothbart SB. Analysis of histone antibody specificity with peptide microarrays. J Vis Exp. 2017;126:55912.
  • Zirwas MJ, Kress DW, Deng J-S. The utility of antihistone antibody screening in the diagnosis of drug-induced lupus erythematosus. Arch Dermatol. 2004;140(4):494–495.
  • Magorivska IB, Bilyy RO, Havrylyuk AM, et al. Anti-histone H1 IgGs from blood serum of systemic lupus erythematosus patients are capable of hydrolyzing histone H1 and myelin basic protein. J Mol Recognit. 2010;23(5):495–502.
  • Kubo M, Ihn H, Yazawa N, et al. Prevalence and antigen specificity of anti-histone antibodies in patients with polymyositis/dermatomyositis. J Invest Dermatol. 1999;112(5):711–715.
  • Deng JS, Sontheimer RD, Lipscomb MF, et al. The binding of antihistone antibodies to Crithidia luciliae kinetoplasts is growth cycle-dependent. Arthritis Rheum. 1985;28(2):163–168.
  • Wasserman E, Levine L. Quantitative micro-complement fixation and its use in the study of antigenic structure by specific antigen-antibody inhibition. J Immunol. 1961;87(3):290–295.
  • Tan EM, Robinson J, Robitaille P. Studies on antibodies to histones by immunofluorescence. Scand J Immunol. 1976;5(6–7):811–818.
  • Fishbein E, Alarcon-Segovia D, Vega JM. Antibodies to histones in systemic lupus erythematosus. Clin Exp Immunol. 1979;36(1):145–150.
  • Vordenbäumen S, Böhmer P, Brinks R, et al. High diagnostic accuracy of histone H4-IgG autoantibodies in systemic lupus erythematosus. Rheumatology. 2018;57(3):533–537.
  • Wallace DJ, Lin H-C, Shen GQ, et al. Antibodies to histone (h2a–h2b)–DNA complexes in the absence of antibodies to double-stranded DNA or to (h2a–h2b) complexes are more sensitive and specific for scleroderma-related disorders than for lupus. Arthritis Rheum. 1994;37(12):1795–1797.
  • Luzhetskaya OP, Sedykh SE, Nevinsky GA. How human H1 histone recognizes DNA. Molecules. 2020;25(19):4556.
  • Araújo-Fernández S, Ahijón-Lana M, Isenberg DA. Drug-induced lupus: including anti-tumour necrosis factor and interferon induced. Lupus. 2014;23(6):545–553.
  • Fritzler MJ. Drugs recently associated with lupus syndromes. Lupus. 1994;3(6):455–459.
  • Borchers AT, Keen CL, Gershwin ME. Drug-induced lupus. Ann N Y Acad Sci. 2007;1108:166–182.
  • Lee AYS, Gordon TP. Antinuclear antibody (ANA) monitoring in drug-induced lupus erythematosus (DILE). Rheumatology. 2021;60(4):2022–2023.
  • De Rycke L, Baeten D, Kruithof E, et al. Infliximab, but not etanercept, induces IgM anti-double-stranded DNA autoantibodies as main antinuclear reactivity: biologic and clinical implications in autoimmune arthritis. Arthritis Rheum. 2005;52(7):2192–2201.
  • Williams EL, Gadola S, Edwards CJ. Anti-TNF-induced lupus. Rheumatology. 2009;48(7):716–720.
  • Vedove CD, Del Giglio M, Schena D, et al. Drug-induced lupus erythematosus. Arch Dermatol Res. 2009;301(1):99–105.
  • Grossman L, Barland P. Histone reactivity of drug-induced antinuclear antibodies. A comparison of symptomatic and asymptomatic patients. Arthritis Rheum. 1981;24(7):927–931.
  • Fritzler MJ, Tan EM. Antibodies to histones in drug-induced and idiopathic lupus erythematosus. J Clin Invest. 1978;62(3):560–567.
  • Burlingame RW, Rubin RL. Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin. J Clin Invest. 1991;88(2):680–690.
  • Portanova JP, Arndt RE, Tan EM, et al. Anti-histone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions. J Immunol. 1987;138(2):446–451.
  • Cohen MG, Pollard KM, Webb J. Antibodies to histones in systemic lupus erythematosus: prevalence, specificity, and relationship to clinical and laboratory features. Ann Rheum Dis. 1992;51(1):61–66.
  • González C, Garcia-Berrocal B, Herráez O, et al. Anti-nucleosome, anti-chromatin, anti-dsDNA and anti-histone antibody reactivity in systemic lupus erythematosus. Clin Chem Lab Med. 2004;42(3):266–272.
  • Shabana AA, El-Ghawet AE, Machaly SA, et al. Anti-chromatin and anti-histone antibodies in Egyptian patients with systemic lupus erythematosus. Clin Rheumatol. 2009;28(6):673–678.
  • Sun X-Y, Shi J, Han L, et al. Anti-histones antibodies in systemic lupus erythematosus: prevalence and frequency in neuropsychiatric lupus. J Clin Lab Anal. 2008;22(4):271–277.
  • Yang J, Xu Z, Sui M, et al. Co-positivity for anti-dsDNA, -nucleosome and -histone antibodies in lupus nephritis is indicative of high serum levels and severe nephropathy. PLoS One. 2015;10(10):e0140441.
  • Cortés-Hernández J, Ordi-Ros J, Labrador M, et al. Antihistone and anti-double-stranded deoxyribonucleic acid antibodies are associated with renal disease in systemic lupus erythematosus. Am J Med. 2004;116(3):165–173.
  • Sui M, Lin Q, Xu Z, et al. Simultaneous positivity for anti-DNA, anti-Nucleosome and anti-Histone antibodies is a marker for more severe lupus nephritis. J Clin Immunol. 2013;33(2):378–387.
  • Yuan F, Wei F, Huang H, et al. The predictive value of autoantibody spectrum on organ damage in patients with systemic lupus erythematosus. Arch Rheumatol. 2019;34(2):157–165.
  • Stemmer C, Tuaillon N, Prieur A-M, et al. Mapping of B-Cell epitopes recognized by antibodies to histones in subsets of juvenile chronic arthritis. Clin Immunol Immunopathol. 1995;76(1):82–89.
  • Sato S, Ihn H, Kikuchi K, et al. Antihistone antibodies in systemic sclerosis. Association with pulmonary fibrosis. Arthritis Rheum. 1994;37(3):391–394.
  • Lee AYS, Chataway T, Colella AD, et al. Quantitative mass spectrometric analysis of autoantibodies as a paradigm shift in autoimmune serology. Front Immunol. 2019;10:2845.
  • Costa O, Monier JC. Antihistone antibodies detected by ELISA and immunoblotting in systemic lupus erythematosus and rheumatoid arthritis. J Rheumatol. 1986;13(4):722–725.
  • Roy Chengappa KN, Betts Carpenter A, Yang ZW, et al. Elevated IgG anti-histone antibodies in a subgroup of medicated schizophrenic patients. Schizophr Res. 1992;7(1):49–54.
  • Boey ML, Peebles CL, Tsay G, et al. Clinical and autoantibody correlations in orientals with systemic lupus erythematosus. Ann Rheum Dis. 1988;47(11):918–923.
  • Shoenfeld Y, Segol G, Segol O, et al. Detection of antibodies to total histones and their subfractions in systemic lupus erythematosus patients and their asymptomatic relatives. Arthritis Rheum. 1987;30(2):169–175.
  • Baranova SV, Dmitrienok PS, Ivanisenko NV, et al. Antibodies to H1 histone from the sera of HIV-infected patients recognize and catalyze site-specific degradation of this histone. J Mol Recognit. 2017;30(3):e2588.
  • Wayaku T, Hasegawa M, Kaji K, et al. Antigen specificity of antihistone antibodies in connective tissue disease patients with anti-U1RNP antibodies. Rheumatol Int. 2007;28(2):113–119.
  • Hasegawa M, Sato S, Kikuchi K, et al. Antigen specificity of antihistone antibodies in systemic sclerosis. Ann Rheum Dis. 1998;57(8):470–475.
  • Rubin RL. Autoantibody specificity in drug-induced lupus and neutrophil-mediated metabolism of lupus-inducing drugs. Clin Biochem. 1992;25(3):223–234.