High expression of pituitary tumor gene family is a predictor for poor prognosis of gastric cancer

References

• Cai Q, Zhu C, Yuan Y, Feng Q, Feng Y, Hao Y, Li J, Zhang K, Ye G, Ye L, et al. 2019. Development and validation of a prediction rule for estimating gastric cancer risk in the Chinese high-risk population: a nationwide multicentre study. Gut. 68:1576–1587.
   PubMed Web of Science ®Google Scholar
• Chandrashekar DS, Bashel B, Balasubramanya SAH, Creighton CJ, Ponce-Rodriguez I, Chakravarthi BVSK, Varambally S. 2017. UALCAN: a portal for facilitating tumor subgroup gene expression and survival analyses. Neoplasia. 19:649–658.
   PubMed Web of Science ®Google Scholar
• Chang L, Zhou G, Soufan O, Xia J. 2020. miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology. Nucleic Acids Res. 48:W244–W251.
   PubMed Web of Science ®Google Scholar
• Chen L, Puri R, Lefkowitz EJ, Kakar SS. 2000. Identification of the human pituitary tumor transforming gene (hPTTG) family: molecular structure, expression, and chromosomal localization. Gene. 248:41–50.
   PubMed Web of Science ®Google Scholar
• Correa P. 2013. Gastric cancer: overview. Gastroenterol Clin North Am. 42:211–217.
   PubMed Web of Science ®Google Scholar
• Fan Y, Siklenka K, Arora SK, Ribeiro P, Kimmins S, Xia J. 2016. miRNet – dissecting miRNA-target interactions and functional associations through network-based visual analysis. Nucleic Acids Res. 44:W135–W141.
   PubMed Web of Science ®Google Scholar
• Fraune C, Yehorov S, Luebke AM, Steurer S, Hube-Magg C, Büscheck F, Höflmayer D, Tsourlakis MC, Clauditz TS, Simon R, et al. 2020. Upregulation of PTTG1 is associated with poor prognosis in prostate cancer. Pathol Int. 70:441–451.
   PubMed Web of Science ®Google Scholar
• Gao G, Xiu D, Yang B, Sun D, Wei X, Ding Y, Ma Y, Wang Z. 2019. miR-129-5p inhibits prostate cancer proliferation via targeting ETV1. Onco Targets Ther. 12:3531–3544.
   PubMedGoogle Scholar
• Grzechowiak I, Graś J, Szymańska D, et al. 2020. The oncogenic roles of PTTG1 and PTTG2 genes and pseudogene PTTG3P in head and neck squamous cell carcinomas. Diagnostics. 10:606.
   Web of Science ®Google Scholar
• Gullo I, Carvalho J, Martins D, Lemos D, Monteiro A, Ferreira M, Das K, Tan P, Oliveira C, Carneiro F, et al. 2018. The transcriptomic landscape of gastric cancer: insights into Epstein-Barr virus infected and microsatellite unstable tumors. Int J Mol Sci. 19:2079.
   PubMed Web of Science ®Google Scholar
• Guo X-C, Li L, Gao Z-H, Zhou H-w, Li J, Wang Q-q. 2019. The long non-coding RNA PTTG3P promotes growth and metastasis of cervical cancer through PTTG1. Aging. 11:1333–1341.
   PubMedGoogle Scholar
• Guo Y, Shao Y, Chen J, Xu S, Zhang X, Liu H. 2016. Expression of pituitary tumor-transforming 2 in human glioblastoma cell lines and its role in glioblastoma tumorigenesis. Exp Ther Med. 11:1847–1852.
   PubMed Web of Science ®Google Scholar
• Győrffy B, Surowiak P, Budczies J, Lánczky A. 2013. Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer. PloS one. 8:e82241.
   PubMed Web of Science ®Google Scholar
• He J, Ge Q, Lin Z, Shen W, Lin R, Wu J, Wang B, Lu Y, Chen L, Liu X, et al. 2020. MiR-129-5p induces cell cycle arrest through modulating HOXC10/cyclin D1 to inhibit gastric cancer progression. FASEB J. 34:8544–8557.
   PubMed Web of Science ®Google Scholar
• Huang G, Guo X, Yang H. 2021. Long noncoding RNA SNHG1 promotes human prostate cancer progression by sponging miR-383-5p. Anti-cancer Drugs. 32:286–295.
   PubMed Web of Science ®Google Scholar
• Huang J-L, Cao S-W, Ou Q-S, Yang B, Zheng S-h, Tang J, Chen J, Hu Y-w, Zheng L, Wang Q. 2018. The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma. Mol Cancer. 17:93.
   PubMed Web of Science ®Google Scholar
• Karimi P, Islami F, Anandasabapathy S, Freedman ND, Kamangar F. 2014. Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol Biomarkers Prev. 23:700–713.
   PubMed Web of Science ®Google Scholar
• Katai H, Ishikawa T, Akazawa K, Isobe Y, Miyashiro I, Oda I, Tsujitani S, Ono H, Tanabe S, Fukagawa T, et al. 2018. Five-year survival analysis of surgically resected gastric cancer cases in Japan: a retrospective analysis of more than 100,000 patients from the nationwide registry of the Japanese gastric cancer Association (2001–2007). Gastric Cancer. 21:144–154.
   PubMed Web of Science ®Google Scholar
• Khorkova O, Hsiao J, Wahlestedt C. 2015. Basic biology and therapeutic implications of lncRNA. Adv Drug Delivery Rev. 87:15–24.
   PubMed Web of Science ®Google Scholar
• Li JH, Liu S, Zhou H, et al. 2014. Starbase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res. 42:D92–D97.
   PubMed Web of Science ®Google Scholar
• Lin X, Yang Y, Guo Y, Liu H, Jiang J, Zheng F, Wu B, et al. 2019. PTTG1 is involved in TNF-α-related hepatocellular carcinoma via the induction of c-myc. Cancer Med. 8:5702–5715.
   PubMedGoogle Scholar
• Liu J, Wang J, Song Y, Ma B, Luo J, Ni Z, Gao P, Sun J, Zhao J, Chen X, et al. 2018. A panel consisting of three novel circulating lncRNAs, is it a predictive tool for gastric cancer? J Cell Mol Med. 22:3605–3613.
   PubMed Web of Science ®Google Scholar
• Liu N, Dou L, Zhang X. 2020. LncRNA PTTG3P sponge absorbs microRNA-155-5P to promote metastasis of colorectal cancer. Onco Targets Ther. 13:5283–5291.
   PubMed Web of Science ®Google Scholar
• Lou W, Ding B, Fan W. 2019. High expression of pseudogene PTTG3P indicates a poor prognosis in human breast cancer. Mol Ther Oncolytics. 14:15–26.
   PubMed Web of Science ®Google Scholar
• Méndez-Vidal C, Gámez-Del Estal MM, Moreno-Mateos MA, Espina-Zambrano ÁG, Torres B, Pintor-Toro JA. 2013. PTTG2 silencing results in induction of epithelial-to-mesenchymal transition and apoptosis. Cell Death Dis. 4:e530.
   PubMed Web of Science ®Google Scholar
• Meng C, Zou Y, Hong W, Bao C, Jia X. 2020. Estrogen-regulated PTTG1 promotes breast cancer progression by regulating cyclin kinase expression. Mol Med. 26:33.
   PubMed Web of Science ®Google Scholar
• Molaei F, Forghanifard MM, Fahim Y, Abbaszadegan MR. 2018. Molecular signaling in tumorigenesis of gastric cancer. Iran Biomed J. 22:217–230.
   PubMedGoogle Scholar
• Noll JE, Vandyke K, Hewett DR, Mrozik KM, Bala RJ, Williams SA, Kok CH, Zannettino ACW. 2015. PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma. J Hematol Oncol. 8:106.
   PubMed Web of Science ®Google Scholar
• Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. 2010. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature. 465:1033–1038.
   PubMed Web of Science ®Google Scholar
• Ren Q, Jin B. 2017. The clinical value and biological function of PTTG1 in colorectal cancer. Biomed Pharmacother. 89:108–115.
   PubMed Web of Science ®Google Scholar
• Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pander A, Chinnaiyan AM. 2004. ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia. 6:1–6.
   PubMed Web of Science ®Google Scholar
• Shih JH, Chen HY, Lin SC, Yeh Y-C, Shen R, Lang Y-D, Wu D-C, Chen C-Y, Chen R-H, Chou T-Y, et al. 2020. Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma. Nucleic Acids Res. 48:1175–1191.
   PubMed Web of Science ®Google Scholar
• Sun X, Wang X, Dong G, Zhang B, et al. 2020. Expression level of miR-383-5p in colorectal cancer patients following neoadjuvant chemotherapy and its clinical significance in the prognosis. Minerva Med.
   Google Scholar
• Vasaikar SV, Straub P, Wang J, Zhang B. 2018. Linkedomics: analyzing multi-omics data within and across 32 cancer types. Nucleic Acids Res. 46:D956–d963.
   PubMed Web of Science ®Google Scholar
• Vlotides G, Eigler T, Melmed S. 2007. Pituitary tumor-transforming gene: physiology and implications for tumorigenesis. Endocr Rev. 28:165–186.
   PubMed Web of Science ®Google Scholar
• Wang Q, Yu J. 2018. MiR-129-5p suppresses gastric cancer cell invasion and proliferation by inhibiting COL1A1. Biochem Cell Biol. 96:19–25.
   PubMedGoogle Scholar
• Wei C, Gao J-J. 2019. Downregulated miR-383-5p contributes to the proliferation and migration of gastric cancer cells and is associated with poor prognosis. PeerJ. 7:e7882.
   PubMed Web of Science ®Google Scholar
• Weng W, Ni S, Wang Y, Xu M, Zhang Q, Yang Y, Wu Y, Xu Q, Qi P, Tan C, et al. 2017. PTTG3P promotes gastric tumour cell proliferation and invasion and is an indicator of poor prognosis. J Cell Mol Med. 21:3360–3371.
   PubMed Web of Science ®Google Scholar
• Xu C, Du Z, Ren S, Liang X, Li H. 2020. MiR-129-5p sensitization of lung cancer cells to etoposide-induced apoptosis by reducing YWHAB. J Cancer. 11:858–866.
   PubMed Web of Science ®Google Scholar
• Xu MD, Dong L, Qi P, Weng W-w, Shen X-h, Ni S-j, Huang D, Tan C, Sheng W-q, Zhou X-y, et al. 2016. Pituitary tumor-transforming gene-1 serves as an independent prognostic biomarker for gastric cancer. Gastric Cancer. 19:107–115.
   PubMed Web of Science ®Google Scholar
• Yeh TS, Wu CW, Hsu KW, et al. 2009. The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2. Cancer Res. 69:5039–5048.
   PubMed Web of Science ®Google Scholar
• Zhang Z, Shi Z. 2019. The pseudogene PTTG3P promotes cell migration and invasion in esophageal squamous cell carcinoma. Open Med. 14:516–522.
   Web of Science ®Google Scholar
• Zheng Y, Guo J, Zhou J, Lu J, Chen Q, Zhang C, Qing C, Koeffler HP, Tong Y. 2015. Foxm1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion. BMC Med Genet. 8:49.
   Google Scholar