Analysis of differentially expressed genes in hypertension and hypertensive cerebral hemorrhage via RNA-sequencing

References

• Andersen CBF, Stodkilde K, Saederup KL, Kuhlee A, Raunser S, Graversen JH, et al. 2017. Haptoglobin. Antioxid Redox Signal. 26:814–831. doi:10.1089/ars.2016.6793.
   PubMed Web of Science ®Google Scholar
• Antonio RC, Ceron CS, Rizzi E, Coelho EB, Tanus-Santos JE, Gerlach RF. 2014. Antioxidant effect of doxycycline decreases MMP activity and blood pressure in SHR. Mol Cell Biochem. 386:99–105. doi:10.1007/s11010-013-1848-7.
   PubMed Web of Science ®Google Scholar
• Astrup LB, Skovgaard K, Rasmussen RS, Iburg TM, Agerholm JS, Aalbæk B, et al. 2019. Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology. Neurol Res. 41:399–412. doi:10.1080/01616412.2019.1573455.
   PubMed Web of Science ®Google Scholar
• Beck D, Thoms JA, Perera D, Schutte J, Unnikrishnan A, Knezevic K, et al. 2013. Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes. Blood. 122:e12–e22. doi:10.1182/blood-2013-03-490425.
   PubMed Web of Science ®Google Scholar
• Bresnick EH, Lee HY, Fujiwara T, Johnson KD, Keles S. 2010. GATA switches as developmental drivers. J Biol Chem. 285:31087–31093. doi:10.1074/jbc.R110.159079.
   PubMed Web of Science ®Google Scholar
• Castro MM, Tanus-Santos JE, Gerlach RF. 2011. Matrix metalloproteinases: targets for doxycycline to prevent the vascular alterations of hypertension. Pharmacol Res. 64:567–572. doi:10.1016/j.phrs.2011.04.002.
   PubMed Web of Science ®Google Scholar
• Collin M, Dickinson R, Bigley V. 2015. Haematopoietic and immune defects associated with GATA2 mutation. Br J Haematol. 169:173–187. doi:10.1111/bjh.13317.
   PubMed Web of Science ®Google Scholar
• Ding R, Lin C, Wei S, Zhang N, Tang L, Lin Y, et al. 2017. Therapeutic benefits of mesenchymal stromal cells in a rat model of hemoglobin-induced hypertensive intracerebral hemorrhage. Mol Cells. 40:133–142. doi:10.14348/molcells.2017.2251.
   PubMed Web of Science ®Google Scholar
• Ding W, Gu Z, Song D, Liu J, Zheng G, Tu C. 2018. Development and validation of the hypertensive intracerebral hemorrhage prognosis models. Medicine. 97:e12446. doi:10.1097/md.0000000000012446.
   PubMed Web of Science ®Google Scholar
• Dore LC, Chlon TM, Brown CD, White KP, Crispino JD. 2012. Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood. 119:3724–3733. doi:10.1182/blood-2011-09-380634.
   PubMed Web of Science ®Google Scholar
• Feigin VL, Lawes CM, Bennett DA, Barker-Collo SL, Parag V. 2009. Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review. Lancet Neurol. 8:355–369. doi:10.1016/s1474-4422(09)70025-0.
   PubMed Web of Science ®Google Scholar
• Feng Y, He J, Liu B, Yang L, Wang Y. 2016. Endoscope-assisted keyhole technique for hypertensive cerebral hemorrhage in elderly patients: a randomized controlled study in 184 patients. Turk Neurosurg. 26:84–89. doi:10.5137/1019-5149.jtn.12669-14.0.
   PubMed Web of Science ®Google Scholar
• Hadzic S, Wu CY, Gredic M, Kojonazarov B, Pak O, Kraut S, et al. 2021. The effect of long-term doxycycline treatment in a mouse model of cigarette smoke-induced emphysema and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 320:L903–l915. doi:10.1152/ajplung.00048.2021.
   PubMed Web of Science ®Google Scholar
• Hanley JM, Haugen TH, Heath EC. 1983. Biosynthesis and processing of rat haptoglobin. J Biol Chem. 258:7858–7869. doi:10.1016/S0021-9258(18)32258-0.
   PubMed Web of Science ®Google Scholar
• Huang Q, Lan T, Lu J, Zhang H, Zhang D, Lou T, et al. 2018. DiDang tang inhibits endoplasmic reticulum stress-mediated apoptosis induced by oxygen glucose deprivation and intracerebral hemorrhage through blockade of the GRP78-IRE1/PERK pathways. Front Pharmacol. 9:1423. doi:10.3389/fphar.2018.01423.
   PubMed Web of Science ®Google Scholar
• Iida S, Baumbach GL, Lavoie JL, Faraci FM, Sigmund CD, Heistad DD. 2005. Spontaneous stroke in a genetic model of hypertension in mice. Stroke. 36:1253–1258. doi:10.1161/01.str.0000167694.58419.a2.
   PubMed Web of Science ®Google Scholar
• Ji W, Zhang Y. 2017. The association of MPO gene promoter polymorphisms with Alzheimer's disease risk in Chinese Han population. Oncotarget. 8:107870–107876. doi:10.18632/oncotarget.22330.
   PubMedGoogle Scholar
• Jin F, Li L, Hao Y, Tang L, Wang Y, He Z. 2021. Identification of candidate blood mRNA biomarkers in intracerebral hemorrhage using integrated microarray and weighted gene co-expression network analysis. Front Genet. 12:707713. doi:10.3389/fgene.2021.707713.
   PubMed Web of Science ®Google Scholar
• Khine HW, Teiber JF, Haley RW, Khera A, Ayers CR, Rohatgi A. 2017. Association of the serum myeloperoxidase/high-density lipoprotein particle ratio and incident cardiovascular events in a multi-ethnic population: observations from the Dallas Heart Study. Atherosclerosis. 263:156–162. doi:10.1016/j.atherosclerosis.2017.06.007.
   PubMed Web of Science ®Google Scholar
• Kim HJ, Wei Y, Wojtkiewicz GR, Lee JY, Moskowitz MA, Chen JW. 2018. Reducing myeloperoxidase activity decreases inflammation and increases cellular protection in ischemic stroke. J Cereb Blood Flow Metab. 39:1864–1877. doi:10.1177/0271678X18771978.
   PubMed Web of Science ®Google Scholar
• Kruyer A, Soplop N, Strickland S, Norris EH. 2015. Chronic hypertension leads to neurodegeneration in the TgSwDI mouse model of Alzheimer's disease. Hypertension. 66:175–182. doi:10.1161/hypertensionaha.115.05524.
   PubMed Web of Science ®Google Scholar
• Kushner I, Mackiewicz A. 1987. Acute phase proteins as disease markers. Dis Markers. 5:1–11.
   PubMed Web of Science ®Google Scholar
• Lai YJ, Chang GJ, Yeh YH, Pang JH, Huang CC, Chen WJ. 2015. Propylthiouracil attenuates experimental pulmonary hypertension via suppression of pen-2, a key component of gamma-secretase. PLoS One. 10:e0137426. doi:10.1371/journal.pone.0137426.
   PubMed Web of Science ®Google Scholar
• Lei Y, Guo P. 2019. Identification of differentially expressed miRNAs and mRNAs in vestibular schwannoma by integrated analysis. BioMed Res Int. 2019:7267816. doi:10.1155/2019/7267816.
   PubMed Web of Science ®Google Scholar
• Lennon MJ, Koncz R, Sachdev PS. 2021. Hypertension and Alzheimer's disease: Is the picture any clearer? Curr Opin Psychiatry. 34:142–148. doi:10.1097/yco.0000000000000684.
   PubMed Web of Science ®Google Scholar
• Leuzy A, Mattsson-Carlgren N, Palmqvist S, Janelidze S, Dage JL, Hansson O. 2022. Blood-based biomarkers for Alzheimer's disease. EMBO Mol Med. 14:e14408. doi:10.15252/emmm.202114408.
   PubMed Web of Science ®Google Scholar
• Li TT, Li XY, Jia LX, Zhang J, Zhang WM, Li YL, et al. 2016. Whole transcriptome analysis of hypertension induced cardiac injury using deep sequencing. Cell Physiol Biochem. 38:670–682. doi:10.1159/000438659.
   PubMedGoogle Scholar
• Maslehaty H, Petridis AK, Barth H, Doukas A, Mehdorn HM. 2012. Treatment of 817 patients with spontaneous supratentorial intracerebral hemorrhage: characteristics, predictive factors and outcome. Clin Pract. 2:e56. doi:10.4081/cp.2012.e56.
   PubMedGoogle Scholar
• May G, Soneji S, Tipping AJ, Teles J, McGowan SJ, Wu M, et al. 2013. Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors. Cell Stem Cell. 13:754–768. doi:10.1016/j.stem.2013.09.003.
   PubMed Web of Science ®Google Scholar
• Meissner A, Minnerup J, Soria G, Planas AM. 2017. Structural and functional brain alterations in a murine model of Angiotensin II-induced hypertension. J Neurochem. 140:509–521. doi:10.1111/jnc.13905.
   PubMed Web of Science ®Google Scholar
• Moonga I, Niccolini F, Wilson H, Pagano G, Politis M. 2017. Hypertension is associated with worse cognitive function and hippocampal hypometabolism in Alzheimer's disease. Eur J Neurol. 24:1173–1182. doi:10.1111/ene.13374.
   PubMed Web of Science ®Google Scholar
• Muiya NP, Wakil S, Al-Najai M, Tahir AI, Baz B, Andres E, et al. 2014. A study of the role of GATA2 gene polymorphism in coronary artery disease risk traits. Gene. 544:152–158. doi:10.1016/j.gene.2014.04.064.
   PubMed Web of Science ®Google Scholar
• Murthy SB, Levy AP, Duckworth J, Schneider EB, Shalom H, Hanley DF, et al. 2015. Presence of haptoglobin-2 allele is associated with worse functional outcomes after spontaneous intracerebral hemorrhage. World Neurosurg. 83:583–587. doi:10.1016/j.wneu.2014.12.013.
   PubMed Web of Science ®Google Scholar
• Nakamura H, Kato M, Nakaya T, Kono M, Tanimura S, Sato T, et al. 2017. Decreased haptoglobin levels inversely correlated with pulmonary artery pressure in patients with pulmonary arterial hypertension: a cross-sectional study. Medicine. 96:e8349. doi:10.1097/md.0000000000008349.
   PubMed Web of Science ®Google Scholar
• Ndrepepa G. 2019. Myeloperoxidase – a bridge linking inflammation and oxidative stress with cardiovascular disease. Clin Chim Acta. 493:36–51. doi:10.1016/j.cca.2019.02.022.
   PubMed Web of Science ®Google Scholar
• Nguyen HL, Lee YJ, Shin J, Lee E, Park SO, McCarty JH, et al. 2011. TGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development. Lab Invest. 91:1554–1563. doi:10.1038/labinvest.2011.124.
   PubMed Web of Science ®Google Scholar
• Odagiri K, Watanabe H. 2015. Effects of the Rho-kinase inhibitor, fasudil, on pulmonary hypertension. Circ J. 79:1213–1214. doi:10.1253/circj.CJ-15-0443.
   PubMed Web of Science ®Google Scholar
• Orkin SH. 2000. Diversification of haematopoietic stem cells to specific lineages. Nat Rev Genet. 1:57–64. doi:10.1038/35049577.
   PubMed Web of Science ®Google Scholar
• Raja SG. 2012. Evaluation of clinical efficacy of fasudil for the treatment of pulmonary arterial hypertension. Recent Pat Cardiovasc Drug Discov. 7:100–104. doi:10.2174/157489012801227238.
   PubMedGoogle Scholar
• Rocanin-Arjo A, Cohen W, Carcaillon L, Frere C, Saut N, Letenneur L, et al. 2014. A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential. Blood. 123:777–785. doi:10.1182/blood-2013-10-529628.
   PubMed Web of Science ®Google Scholar
• Rodrigues NP, Janzen V, Forkert R, Dombkowski DM, Boyd AS, Orkin SH, et al. 2005. Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis. Blood. 106:477–484. doi:10.1182/blood-2004-08-2989.
   PubMed Web of Science ®Google Scholar
• Rodrigues NP, Tipping AJ, Wang Z, Enver T. 2012. GATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia. Int J Biochem Cell Biol. 44:457–460. doi:10.1016/j.biocel.2011.12.004.
   PubMed Web of Science ®Google Scholar
• Sun Y, Xu B, Zhang Q. 2018. Nerve growth factor in combination with Oxiracetam in the treatment of Hypertensive Cerebral Hemorrhage. Pak J Med Sci. 34:73–77. doi:10.12669/pjms.341.13395.
   PubMed Web of Science ®Google Scholar
• Sutherland GR, Auer RN. 2006. Primary intracerebral hemorrhage. J Clin Neurosci. 13:511–517. doi:10.1016/j.jocn.2004.12.012.
   PubMed Web of Science ®Google Scholar
• Tang DD. 2018. The dynamic actin cytoskeleton in smooth muscle. Adv Pharmacol. 81:1–38. doi:10.1016/bs.apha.2017.06.001.
   PubMedGoogle Scholar
• Tian DZ, Wei W, Dong YJ. 2016. Influence of COL1A2 gene variants on the incidence of hypertensive intracerebral hemorrhage in a Chinese population. Genet Mol Res. 15:15017369. doi:10.4238/gmr.15017369.
   Web of Science ®Google Scholar
• Tsai FY, Keller G, Kuo FC, Weiss M, Chen J, Rosenblatt M, et al. 1994. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature. 371:221–226. doi:10.1038/371221a0.
   PubMed Web of Science ®Google Scholar
• Ungvari Z, Toth P, Tarantini S, Prodan CI, Sorond F, Merkely B, et al. 2021. Hypertension-induced cognitive impairment: from pathophysiology to public health. Nat Rev Nephrol. 17:639–654. doi:10.1038/s41581-021-00430-6.
   PubMed Web of Science ®Google Scholar
• Wagner AH, Coffman AC, Ainscough BJ, Spies NC, Skidmore ZL, Campbell KM, et al. 2016. DGIdb 2.0: mining clinically relevant drug-gene interactions. Nucleic Acids Res. 44:D1036–D1044. doi:10.1093/nar/gkv1165.
   PubMed Web of Science ®Google Scholar
• Wakisaka Y, Chu Y, Miller JD, Rosenberg GA, Heistad DD. 2010a. Critical role for copper/zinc-superoxide dismutase in preventing spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice. Stroke. 41:790–797. doi:10.1161/strokeaha.109.569616.
   PubMed Web of Science ®Google Scholar
• Wakisaka Y, Chu Y, Miller JD, Rosenberg GA, Heistad DD. 2010b. Spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice. J Cereb Blood Flow Metab. 30:56–69. doi:10.1038/jcbfm.2009.183.
   PubMed Web of Science ®Google Scholar
• Wang Y, Wu N, Liu J, Wu Z, Dong D. 2015. FusionCancer: a database of cancer fusion genes derived from RNA-seq data. Diagn Pathol. 10:131. doi:10.1186/s13000-015-0310-4.
   PubMed Web of Science ®Google Scholar
• Xiang Y, Xin J, Le W, Yang Y. 2020. Neurogranin: a potential biomarker of neurological and mental diseases. Front Aging Neurosci. 12:584743. doi:10.3389/fnagi.2020.584743.
   PubMed Web of Science ®Google Scholar
• Youwakim J, Girouard H. 2021. Inflammation: a mediator between hypertension and neurodegenerative diseases. Am J Hypertens. 34:1014–1030. doi:10.1093/ajh/hpab094.
   PubMed Web of Science ®Google Scholar
• Yuasa I, Umetsu K, Vogt U, Nakamura H, Nanba E, Tamaki N, et al. 1997. Human orosomucoid polymorphism: molecular basis of the three common ORM1 alleles, ORM1*F1, ORM1*F2, and ORM1*S. Hum Genet. 99:393–398. doi:10.1007/s004390050378.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Wu S. 2017. Effects of fasudil on pulmonary hypertension in clinical practice. Pulm Pharmacol Ther. 46:54–63. doi:10.1016/j.pupt.2017.08.002.
   PubMed Web of Science ®Google Scholar