Understanding Opioid Loneliness and Stigma in Rural Counties

References

• Akdağ, E. M., Kotan, V. O., Kose, S., Tıkır, B., Aydemir, M. Ç., Okay, İ. T., … Özkaya, G. (2018). The relationship between internalized stigma and treatment motivation, perceived social support, depression and anxiety levels in opioid use disorder. Psychiatry and Clinical Psychopharmacology, 28(4), 394–401. https://doi.org/10.1080/24750573.2018.1478190
   Web of Science ®Google Scholar
• American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders – 5 (5th ed.).
   Google Scholar
• Armstrong, J. (2015). Loneliness and perceived stigmatization among older adults enrolled in opiate substitution treatment programs and the utilization of mental health services [Doctoral dissertation, Antioch University Seattle]. https://aura.antioch.edu/etds/246/
   Google Scholar
• Barabási, A. (2016). Network Science. Cambridge University Press.
   Google Scholar
• Beachler, T., Zeller, T. A., Heo, M., Lanzillotta, R. J., & Litwin, A. H. (2021). Community attitudes toward opioid use disorder and medication for opioid use disorder in a rural Appalachian county. The Journal of Rural Health, 37(1), 29–34. https://doi.org/10.1111/jrh.12503
   PubMed Web of Science ®Google Scholar
• Beck, J. S. (2021). Cognitive behavior therapy: Basics and beyond (3rd ed.). Guilford Press.
   Google Scholar
• Beck, A. T., Wright, F. D., Newman, C. F., & Liese, B. S. (1993). Cognitive therapy of substance abuse. Guilford Press.
   Google Scholar
• Broz, D., Zibbell, J., Foote, C., Roseberry, J. C., Patel, M. R., Conrad, C., … Duwve, J. M. (2018). Multiple injections per injection episode: High-risk injection practice among people who injected pills during the 2015 HIV outbreak in Indiana. International Journal of Drug Policy, 52, 97–101. https://doi.org/10.1016/j.drugpo.2017.12.003
   PubMed Web of Science ®Google Scholar
• Cacioppo, J. T., Hughes, M. E., Waite, L. J., Hawkley, L. C., & Thisted, R. A. (2006). Loneliness as a specific risk factor for depressive symptoms: Cross-sectional and longitudinal analyses. Psychology and Aging, 21(1), 140–151. https://doi.org/10.1037/0882-7974.21.1.140
   PubMed Web of Science ®Google Scholar
• Cacioppo, J. T., & Patrick, W. X. (2009). Loneliness: Human nature and the need for social connection. North & Company.
   Google Scholar
• Cai, M., Shah, N., Li, J., Chen, W.-H., Cuomo, R. E., Obradovich, N., … Lavorgna, L. (2020). Identification and characterization of tweets related to the 2015 Indiana HIV outbreak: A retrospective infoveillance study. Public Library of Science ONE, 15(8), 1–13. https://doi.org/10.1371/journal.pone.0235150
   Google Scholar
• Calabresi, M. (2015). The Price of Relief. (Cover story). Time Magazine, 185(22), 26–33.
   Google Scholar
• Center for Substance Abuse Treatment. (2004). Clinical guidelines for the use of buprenorphine in the treatment of opioid addiction. Treatment Improvement Protocol (TIP) Series 40. DHHS Publication No. (SMA) 04-3939. Substance Abuse and Mental Health Services Administration.
   Google Scholar
• Cheetham, A., Picco, L., Barnett, A., Lubman, D. I., & Nielsen, S. (2022). The impact of stigma on people with opioid use disorder, opioid treatment, and policy. Substance Abuse and Rehabilitation, 13, 1–12. https://doi.org/10.2147/SAR.S304566
   PubMed Web of Science ®Google Scholar
• Christie, N. C. (2021). The role of social isolation in opioid addiction. Social Cognitive and Affective Neuroscience, 16(7), 645–656. https://doi.org/10.1093/scan/nsab029
   PubMed Web of Science ®Google Scholar
• Cortina, J. M. (1993). What is coefficient alpha? An examination of theory and applications. Journal of Applied Psychology, 78(1), 98–104. https://doi.org/10.1037/0021-9010.78.1.98
   Web of Science ®Google Scholar
• Estreet, A., Archibald, P., Tirmazi, M. T., Goodman, S., & Cudjoe, T. (2017). Exploring social work student education: The effect of a harm reduction curriculum on student knowledge and attitudes regarding opioid use disorders. Substance Abuse, 38(4), 369–375. https://doi.org/10.1080/08897077.2017.1341447
   PubMed Web of Science ®Google Scholar
• Ezell, J. M., Walters, S., Friedman, S. R., Bolinski, R., Jenkins, W. D., Schneider, J., … Pho, M. T. (2021). Stigmatize the use, not the user? Attitudes on opioid use, drug injection, treatment, and overdose prevention in rural communities. Social Science & Medicine, 268, N.PAG. https://doi.org/10.1016/j.socscimed.2020.113470
   PubMed Web of Science ®Google Scholar
• Gregory, V. L., Jr. (2019). Cognitive-behavioral group therapy and buprenorphine: Balancing methodological rigor and community partner ethical concerns in efficacy-effectiveness trials. Ethics & Behavior, 30(5), 364–384. https://doi.org/10.1080/10508422.2019.1604233
   Web of Science ®Google Scholar
• Gregory, V. L., Jr., Ofner, S., & Ellis, R. J. (2024). O-Know opioid knowledge test: Development and psychometric testing in a community sample. Journal of Psychoactive Drugs, 56(1), 135–145. https://doi.org/10.1080/02791072.2022.2147883
   PubMed Web of Science ®Google Scholar
• Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352
   PubMed Web of Science ®Google Scholar
• Hupcey, J. E. (1998). Clarifying the social support theory-research linkage. Journal of Advanced Nursing (Wiley-Blackwell), 27(6), 1231–1241. https://doi.org/10.1046/j.1365-2648.1998.01231.x
   PubMed Web of Science ®Google Scholar
• Jensen, E. J., Wieling, E., & Mendenhall, T. (2020). A phenomenological study of clinicians’ perspectives on barriers to rural mental health care. Journal of Rural Mental Health, 44(1), 51–61. https://doi.org/10.1037/rmh0000125
   Google Scholar
• Kantrowitz-Gordon, I., Price, C., Rudolf, V., Downey, G., & Castagnola, K. (2022). Exploring perinatal nursing care for opioid use disorder: knowledge, stigma, and compassion. Journal of Perinatal & Neonatal Nursing, 36(4), 353–361. https://doi.org/10.1097/JPN.0000000000000587
   PubMed Web of Science ®Google Scholar
• Kennedy-Hendricks, A., Barry, C. L., Gollust, S. E., Ensminger, M. E., Chisolm, M. S., & McGinty, E. E. (2017). Social stigma toward persons with prescription opioid use disorder: Associations with public support for punitive and public health–oriented policies. Psychiatric Services, 68(5), 462–469. https://doi.org/10.1176/appi.ps.201600056
   PubMed Web of Science ®Google Scholar
• Knopf, A. (2017). Jerome Adams, syringe services champion, nominated for SG. Alcoholism & Drug Abuse Weekly, 29(27), 7–8. https://doi.org/10.1002/adaw.31790
   Google Scholar
• Koob, G. F., & Volkow, N. D. (2016). Neurobiology of addiction: A neurocircuitry analysis. The Lancet Psychiatry, 3(8), 760–773. https://doi.org/10.1016/S2215-0366(16)00104-8
   PubMed Web of Science ®Google Scholar
• Lawson, K. M., Back, S. E., Hartwell, K. J., Moran-Santa Maria, M., & Brady, K. T. (2013). A comparison of trauma profiles among individuals with prescription opioid, nicotine, or cocaine dependence. The American Journal on Addictions, 22(2), 127–131. https://doi.org/10.1111/j.1521-0391.2013.00319.x
   PubMed Web of Science ®Google Scholar
• Lee, J., & Cagle, J. G. (2017). Validating the 11-item Revised University of California Los Angeles scale to assess loneliness among older adults: An evaluation of factor structure and other measurement properties. The American Journal of Geriatric Psychiatry, 25(11), 1173–1183. https://doi.org/10.1016/j.jagp.2017.06.004
   PubMed Web of Science ®Google Scholar
• Li, F., Xu, Y.-M., Zhu, J.-H., Lu, J., & Zhong, B.-L. (2017). Pain of methadone-maintained heroin addicts: Lonelier individuals feel more intense pain. Oncotarget, 8(45), 79948–79952. https://doi.org/10.18632/oncotarget.20387
   PubMedGoogle Scholar
• Lopez, S. J., Pedrotti, J. T., & Snyder, C. R. (2019). Positive psychology: The scientific and practical explorations of human strengths (4th ed.). Sage.
   Google Scholar
• Mahmoud, K. F., Lindsay, D., Scolieri, B. B., Hagle, H., Puskar, K. R., & Mitchell, A. M. (2018). Changing BSN students’ stigma toward patients who use alcohol and opioids through screening, brief intervention, and referral to treatment (SBIRT) education and training: A pilot study. Journal of the American Psychiatric Nurses Association, 24(6), 510–521. https://doi.org/10.1177/1078390317751624
   PubMed Web of Science ®Google Scholar
• Makhinson, M., Seshia, S. S., Young, G. B., Smith, P. A., Stobart, K., & Guha, I. N. (2021). The iatrogenic opioid crisis: An example of “institutional corruption of pharmaceuticals”? Journal of Evaluation in Clinical Practice, 27(5), 1033–1043. https://doi.org/10.1111/jep.13566
   PubMed Web of Science ®Google Scholar
• Miller, W. R., & Rollnick, S. (2013). Motivational Interviewing: Helping People Change (3rd ed.). Guilford Press.
   Google Scholar
• Montiel Ishino, F. A., McNab, P. R., Gilreath, T., Salmeron, B., & Williams, F. (2020). A comprehensive multivariate model of biopsychosocial factors associated with opioid misuse and use disorder in a 2017–2018 United States national survey. BMC Public Health, 20(1), 1740. https://doi.org/10.1186/s12889-020-09856-2
   PubMed Web of Science ®Google Scholar
• Moore, M. D., Ali, S., Burnich-Line, D., Gonzales, W., & Stanton, M. V. (2020). Stigma, opioids, and Public Health Messaging: The need to disentangle behavior from identity. American Journal of Public Health, 110(6), 807–810. https://doi.org/10.2105/AJPH.2020.305628
   PubMed Web of Science ®Google Scholar
• Naragon-Gainey, K., & Brown, T. A. (2015). Enhancing measurement validation in cognitive clinical research with structural equation modeling and item response theory. In G. P. Brown & D. A. Clark (Eds.), Assessment in cognitive therapy (pp. 268–290). The Guilford Press.
   Google Scholar
• Nunnally, J. C., & Bernstein, I. H. (1994). Psychometric theory (3rd ed.). McGraw-Hill.
   Google Scholar
• Olsen, Y., & Sharfstein, J. M. (2014). Confronting the stigma of opioid use disorder – And its treatment. JAMA, Journal of the American Medical Association, 311(14), 1393–1394. https://doi.org/10.1001/jama.2014.2147
   PubMed Web of Science ®Google Scholar
• Palamar, J. J., Halkitis, P. N., & Kiang, M. V. (2013). Perceived public stigma and stigmatization in explaining lifetime illicit drug use among emerging adults. Addiction Research & Theory, 21(6), 516–525. https://doi.org/10.3109/16066359.2012.762508
   Web of Science ®Google Scholar
• Palamar, J. J., Kiang, M. V., & Halkitis, P. N. (2011). Development and psychometric evaluation of scales that assess stigma associated with illicit drug users. Substance Use & Misuse, 46(12), 1457–1467. https://doi.org/10.3109/10826084.2011.596606
   PubMed Web of Science ®Google Scholar
• Palamar, J. J., Kiang, M. V., & Halkitis, P. N. (2012). Predictors of stigmatization towards use of various illicit drugs among emerging adults. Journal of Psychoactive Drugs, 44(3), 243–251. https://doi.org/10.1080/02791072.2012.703510
   PubMed Web of Science ®Google Scholar
• Pear, V. A., Ponicki, W. R., Gaidus, A., Keyes, K. M., Martins, S. S., Fink, D. S., … Cerdá, M. (2019). Urban-rural variation in the socioeconomic determinants of opioid overdose. Drug and Alcohol Dependence, 195, 66–73. https://doi.org/10.1016/j.drugalcdep.2018.11.024
   PubMed Web of Science ®Google Scholar
• Peduzzi, P., Concato, J., Kemper, E., Holford, T. R., & Feinstein, A. R. (1996). A simulation study of the number of events per variable in logistic regression analysis. Journal of Clinical Epidemiology, 49(12), 1373–1379. https://doi.org/10.1016/s0895-4356(96)00236-3
   PubMed Web of Science ®Google Scholar
• Peltz, G., & Südhof, T. C. (2018). The neurobiology of opioid addiction and the potential for prevention strategies. JAMA, 319(20), 2071–2072. https://doi.org/10.1001/jama.2018.3394
   PubMed Web of Science ®Google Scholar
• Purdue University. (2023). Geographic classifications. https://pcrd.purdue.edu/ruralindianastats/geographic-classifications.php
   Google Scholar
• Ratycz, M. C., Papadimos, T. J., & Vanderbilt, A. A. (2018). Addressing the growing opioid and heroin abuse epidemic: A call for medical school curricula. Medical Education Online, 23(1), 1466574. https://doi.org/10.1080/10872981.2018.1466574
   PubMed Web of Science ®Google Scholar
• Savage, S. R. (2002). Assessment for addiction in pain-treatment settings. The Clinical Journal of Pain, 18(4), S28–S38. https://doi.org/10.1097/00002508-200207001-00004
   PubMed Web of Science ®Google Scholar
• Sawyer, J. L., Shrestha, S., Pustz, J. C., Gottlieb, R., Nichols, D., Van Handel, M., … Stopka, T. J. (2021). Characterizing opioid-involved overdose risk in local communities: An opioid overdose vulnerability assessment across Indiana, 2017. Preventive Medicine Reports, 24, 101538. https://doi.org/10.1016/j.pmedr.2021.101538
   PubMedGoogle Scholar
• Schmitt, N. (1996). Uses and abuses of coefficient alpha. Psychological Assessment, 8(4), 350–353. https://doi.org/10.1037/1040-3590.8.4.350
   Web of Science ®Google Scholar
• Schulz, K. F., Altman, D. G., & Moher, D. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomized trials. PloS Medicine, 7(3), 1–7. https://doi.org/10.1371/journal.pmed.1000251
   Web of Science ®Google Scholar
• Scorsone, K. L., Haozous, E. A., Hayes, L., & Cox, K. J. (2021). Ending the chase: Experiences of rural individuals with opioid use disorder. Substance Use & Misuse, 56(8), 1224–1231. https://doi.org/10.1080/10826084.2021.1914109
   PubMed Web of Science ®Google Scholar
• U.S. Department of Agriculture. (n.d.). Drug overdose deaths in the United States. https://opioidmisusetool.norc.org/
   Google Scholar
• Valtorta, N. K., Kanaan, M., Gilbody, S., Ronzi, S., & Hanratty, B. (2016). Loneliness and social isolation as risk factors for coronary heart disease and stroke: Systematic review and meta-analysis of longitudinal observational studies. Heart (British Cardiac Society), 102(13), 1009–1016. https://doi.org/10.1136/heartjnl-2015-308790
   PubMed Web of Science ®Google Scholar
• Victor, G., Lee, G., Pozo, B. D., Silverstein, S., Zettner, C., Cason, R., & Ray, B. (2022). Medications for Opioid Use Disorder in the Criminal/Legal System: Knowledge, beliefs, and attitudes among rural community-based stakeholders. Journal of Drug Issues, 52(3), 389–405. https://doi.org/10.1177/00220426221076800
   Web of Science ®Google Scholar
• Volkow, N. D., & Koob, G. (2015). Brain disease model of addiction: Why is it so controversial? The Lancet Psychiatry, 2(8), 677–679. https://doi.org/10.1016/S2215-0366(15)00236-9
   PubMed Web of Science ®Google Scholar
• Walsh, S. L., & Long, K. Q. X. (2019). Deploying science to change hearts and minds: Responding to the opioid crisis. Preventive Medicine, 128, 105780. https://doi.org/10.1016/j.ypmed.2019.105780
   PubMed Web of Science ®Google Scholar
• Wenzel, A., Liese, B. S., Beck, A. T., & Friedman-Wheeler, D. G. (2012). Group cognitive therapy for addictions. Guilford Press.
   Google Scholar
• Wilson, D. B. (n.d.). Practical meta-analysis effect size calculator. George Mason University. https://campbellcollaboration.org/escalc/html/EffectSizeCalculator-SMD1.php
   Google Scholar
• Wilson R. S., Krueger K. R., Arnold S. E., Schneider J. A., Kelly J. F., Barnes L. L., Tang Y., & Bennett D. A. (2007). Loneliness and Risk of Alzheimer Disease. Archives of general psychiatry, 64(2), 234. https://doi.org/10.1001/archpsyc.64.2.234
   PubMed Web of Science ®Google Scholar
• Woods, J. S., & Joseph, H. (2015). Stigma from the viewpoint of the patient. Journal of Addictive Diseases, 34(2–3), 238–247. https://doi.org/10.1080/10550887.2015.1059714
   PubMed Web of Science ®Google Scholar
• Zeller, T. A., Beachler, T., Diaz, L., Thomas, R. P., Heo, M., Lanzillotta-Rangeley, J., & Litwin, A. H. (2022). Attitudes toward syringe exchange programs in a rural Appalachian community. Journal of Addictive Diseases, 40(2), 227–234. https://doi.org/10.1080/10550887.2021.1979837
   PubMed Web of Science ®Google Scholar