Basella- an Underutilized Green Leafy Vegetable with a Potential for Functional Food Development

References

• Babbar, N.; Oberoi, H. S.; Uppal, D. S.; Patil, R. T. Total Phenolic Content and Antioxidant Capacity of Extracts Obtained from Six Important Fruit Residues. Food Res. Int. 2011, 44(1), 391–396. DOI: 10.1016/j.foodres.2010.10.001.
   Web of Science ®Google Scholar
• Babbar, N.; Oberoi, H. S.; Sandhu, S. K.; Bhargav, V. K. Influence of Different Solvents in Extraction of Phenolic Compounds from Vegetable Residues and Their Evaluation as Natural Sources of Antioxidants. J. Food Sci. Technol. 2014, 51, 2568–2575.
   PubMed Web of Science ®Google Scholar
• Babbar, N.; Oberoi, H. S.; Sandhu, S. K. Therapeutic and Nutraceutical Potential of Bioactive Compounds Extracted from Fruit Residues. Crit. Rev. Food Sci. Nutr. 2015, 55, 319–337.
   PubMed Web of Science ®Google Scholar
• Sommerburg, O.; Keunen, J.; Bird, A.; Kuijk, F. J. G. M. Fruits and Vegetables that are Sources for Lutein and Zeaxanthin: The Macular Pigment in Human Eyes. Br. J. Ophthalmol. 1998, 82, 907–910.
   PubMed Web of Science ®Google Scholar
• Liu, S.; Manson, J. E.; Lee, I. M.; Cole, S. R.; Hennekens, C. H.; Willett, W. C.; Buring, J. E. Fruit and Vegetable Intake and Risk of Cardiovascular Disease: The Women’s Health Study. Am. J. Clin. Nutr. 2000, 72, 922–928.
   PubMed Web of Science ®Google Scholar
• Boeing, H.; Bechthold, A.; Bub, A.; Ellinger, S.; Haller, D.; Kroke, A.; Leschik-Bonnet, E.; Muller, M. J.; Oberritter, H.; Schulze, M.; et al. Critical Review: Vegetables and Fruit in the Prevention of Chronic Diseases. Eur. J. Nutr. 2012, 51, 637–663.
   PubMed Web of Science ®Google Scholar
• Oyebode, O.; Gordon-Dseagu, V.; Walker, V.; Mindell, J. S. Fruit and Vegetable Consumption and All-cause, Cancer and CVD Mortality: Analysis of Health Survey for England Data. J Epidemiol Community Health. 2014, 68, 856–862.
   PubMed Web of Science ®Google Scholar
• Gopalan, C.; Rama Shastri, B. V.; Balasubramanian, S. C. Nutritive Value of Indian Foods; National Institute of Nutrition (Indian Council of Medical Research): New Delhi, India, 2009; pp 27–31.
   Google Scholar
• Gupta, S.; Gowri, B. S.; Jyothi Lakshmi, A.; Prakash, J. Retention of Nutrients in Green Leafy Vegetables on Dehydration. J. Food Sci. Technol. 2013, 50, 918–925.
   PubMed Web of Science ®Google Scholar
• George, B.; Kaur, C.; Khurdiya, D. S.; Kapoor, H. C. Antioxidants in Tomato (Lycopersium Esculentum) as a Function of Genotype. Food Chemistry. 2004, 84(1), 45–51. DOI: 10.1016/S0308-8146(03)00165-1.
   Web of Science ®Google Scholar
• Chandra, H. M.; Ramalingam, S. Antioxidant Potentials of Skin, Pulp, and Seed Fractions of Commercially Important Tomato Cultivars. Food Sci. Biotechnol. 2011, 20, 15–21.
   Web of Science ®Google Scholar
• Vimala, B.; Nambisan, B.; Hariprakash, B. Retention of Carotenoids in Orange-fleshed Sweet Potato during Processing. J. Food Sci. Tech. 2011, 48, 520–524.
   PubMed Web of Science ®Google Scholar
• Koley, T. K.; Singh, S.; Khemariya, P.; Sarkar, A.; Kaur, C., .; Chaurasia, S. N. S.; Naik, P. S. Evaluation of Bioactive Properties of Indian Carrot (Daucus Carota L.): A Chemometric Approach. Food Res. Int. 2014, 60, 76–85.
   Web of Science ®Google Scholar
• Yang, Y.; Huang, C. Y.; Peng, S. S.; Li, J. Carotenoid Analysis of Several Dark-green Leafy Vegetables Associated with a Lower Risk of Cancers. Biomed. Environ. Sci. 1996, 9, 386–392.
   PubMedGoogle Scholar
• Raju, M.; Varakumar, S.; Lakshminarayana, R.; Krishnakantha, T. P.; Baskaran, V. Carotenoid Composition and Vitamin A Activity of Medicinally Important Green Leafy Vegetables. Food Chem. 2007, 101, 1598–1605.
   Web of Science ®Google Scholar
• Flyman, M. V.; Afolayan, A. J. The Suitability of Wild Vegetables for Alleviating Human Dietary Deficiencies. S. Afr. J. Bot. 2006, 72, 492–497.
   Web of Science ®Google Scholar
• Dhingra, D.; Michael, M.; Rajput, H.; Patil, R. T. Dietary Fibre in Foods: A Review. J. Food Sci. Technol. 2012, 49(3), 255–266.
   PubMed Web of Science ®Google Scholar
• Pattan, N.; Usha Devi, C. Micronutrient and Anti Nutrient Components of Selected Unconventional Leafy Vegetables in Bangalore City, India. Res. J. Recent Sci. 2014, 3, 393–395.
   Google Scholar
• Scott, J.; Rebeille, F.; Fletches, J. Folic Acid and Folates: The Feasibility for Nutritional Enhancement in Plant Foods. J. Sci. Food Agric. 2000, 80(7), 795–824.
   Web of Science ®Google Scholar
• Cooper, A. J.; Forouhi, N. G.; Ye, Z.; Buijsse, B.; Arriola, L.; Balkau, B.; Barricarte, A.; Beulens, J. W.; Boeing, H.; Büchner, F. L.; et al. Fruit and Vegetable Intake and Type 2 Diabetes: EPIC-InterAct Prospective Study and Meta-analysis. Eur. J. Clin. Nutr. 2012, 66, 1082–1092.
   PubMed Web of Science ®Google Scholar
• Hung, H.; Joshipura, K. J.; Jiang, R.; Hu, F. B.; Hunter, D.; Smith-Warner, S. A.; Colditz, G. A.; Rosner, B.; Spiegelman, D.; Willett, W. C. Fruit and Vegetable Intake and Risk of Major Chronic Disease. J Nat. Cancer Inst. 2004, 96, 1577–1584.
   PubMed Web of Science ®Google Scholar
• Hebbar, S. S.; Harsha, V. H.; Shripathi, V.; Hegde, G. R. Ethnomedicine of Dharwad District in Karnataka, India-plants Used in Oral Health Care. J. Ethnopharmacol. 2004, 94, 261–266.
   PubMed Web of Science ®Google Scholar
• IPGRI. Neglected and Underutilized Plant Species: Strategic Action Plan of the International Plant Genetic Resources Institute; International Plant genetic Resources institute: Rome. Italy, 2002.
   Google Scholar
• Peter, K. V.; Hazra, P. Handbook of Vegetables; Studium Press LLc: U.S.A, 2015; pp 381–383.
   Google Scholar
• Adhikari, R.; Naveen Kumar, H. N.; Shruthi, S. D. A Review on Medicinal Importance of Basella Alba L. Int. J. Pharm. Sci. Drug Res. 2012, 4, 110–114.
   Google Scholar
• Oloyede, F. M.; Oloyede, F. A.; Obuotor, F. M. Comparative Studies of Chemical Compositions of Two Species Of. Basella. App Sci Report. 2013, 3(2), 121–124.
   Google Scholar
• Asaolu, S. S.; Adefemi, O. S.; Oyakilome, I. G.; Ajibulu, K. E.; Asaolu, M. F. Proximate and Mineral Composition of Nigerian Leafy Vegetables. J. Food Res. 2012, 1, 214–218.
   Google Scholar
• Maisuthisakul, P.; Pasuk, S.; Ritthiruangdej, P. Relationship between Antioxidant Properties and Chemical Composition of Some Thai Plants. J. Food Compos. Anal. 2008, 21, 229–240.
   Web of Science ®Google Scholar
• Omoyeni, O. A.; Olaofe, O.; Ainyeye, R. O. Amino Acid Composition of Ten Commonly Eaten Indigenous Leafy Vegetables of South-west Nigeria. World J. Nutr. Health. 2015, 3, 16–21.
   Google Scholar
• Sravan Kumar, S.; Manoj, P.; Giridhar, P. Nutritional Facts and Functional Attributes of Foliage of Basella Sp. LWT- Food Sci. Technol. 2015, 64, 468–474.
   Web of Science ®Google Scholar
• Haskell, M. J.; Jamil, K. M.; Hassan, F.; Peerson, J. M.; Hossain, M. I.; Fuchs, G. J.; Brown, K. H. Daily Consumption of Indian Spinach (Basella Alba) or Sweet Potatoes Has A Positive Effect on Total-body Vitamin A Stores in Bangladeshi Men. Am. J. Clin. Nutr. 2004, 80, 705–714.
   PubMed Web of Science ®Google Scholar
• Teixeira, E. M. B.; Carvalho, M. R. B.; Neves, V. A.; Silva, M. A.; Arantes-Pereira, L. Chemical Characteristics and Fractionation of Proteins from Moringa Oleifera Lam. Leaves. Food Chem. 2014, 147, 51–54.
   PubMed Web of Science ®Google Scholar
• Bunea, A.; Andjelkovic, M.; Socaciu, C.; Bobis, O.; Neacus, M.; Verhe, R.; Camp, J. V. Total and Individual Carotenoids and Phenolic Acids Content in Fresh, Refrigerated and Processed Spinach (Spinacia Oleracea). Food Chem. 2008, 108(2), 649–656.
   PubMed Web of Science ®Google Scholar
• Banerjee, S.; Adak, K.; Adak, M. M.; Ghosh, S.; Chatterjee, A. Effect of Some Antinutritional Factors on the Bioavailability of Minerals along with the Study of Chemical Constituents and Antioxidant Property in Typhonium Trilobatum and Spinacia Oleracea. Chem Sci Rev Lett. 2015, 4(14), 429–439.
   Google Scholar
• Bamidele, O.; Akinnuga, A. M.; Olorunfemi, J. O.; Odetola, O. A.; Oparaji, C. K.; Ezeigbo, N. Effects of Aqueous Extract of Basella Alba Leaves on Haematological and Biochemical Parameters in Albino Rats. Afr. J. Biotechnol. 2010, 9, 6952–6955.
   Web of Science ®Google Scholar
• Sonkar, S. D.; Gupta, R.; Saraf, S. A. Effect of Basella Rubra L. Leaf Extract on Haematological Parameters and Amylase Activity. Pharmacol Commun. 2012, 2(3), 10–13.
   Google Scholar
• Adedosu, O. T.; Adekunle, A. S.; Adedeji, A. L.; Afolabi, O. K.; Oyedeji, T. A. Antioxidant and Anti-lipidoperoxidation Potentials of the Ethylacetate and Chloroform Extracts of Basella Alba Leaves. Asian J. Nat. Appl. Sci. 2013, 2, 81–88.
   Google Scholar
• Siriwatanametanon, N.; Fiebich, B. L.; Efferth, T.; Prieto, J. M.; Heinrich, M. Traditionally Used Thai Medicinal Plants: In Vitro Anti-inflammatory, Anticancer and Antioxidant Activities. J Ethnopharm. 2010, 130, 196–207.
   PubMed Web of Science ®Google Scholar
• Thirupathi, B.; Rao, G. Comparitive Phytochemical Quantification in Green and Purple Varities of Basellaalba for Preventive Management of Nutritional Deficiency and Stress Related Diseases. World J Pharm Pharmaceutical Sci. 2014, 3, 1061–1071.
   Google Scholar
• Kumar, B. R.; Anupam, A.; Manchikanti, P.; Rameshbabu, A. P.; Dasgupta, S.; Dhara, S. Identification and Characterization of Bioactive Phenolic Constituents, Anti-proliferative and Anti-angiogenic Activity of Stem Extracts of Basella Alba and Rubra. J. Food Sci. Technol. 2018, 55(5), 1675–1684.
   PubMed Web of Science ®Google Scholar
• Anusuya, N.; Gomathi, R.; Manian, S.; Sivaram, V.; Menon, A. Evaluation of Basella Rubra L., Rumex Nepalensis Spreng and Commelina Benghalensis L. For Antioxidant Activity. Int. J. Pharm. Pharm. Sci. 2012, 4(3), 714–720.
   Google Scholar
• Thavamani, B. S.; Subburaj, V. In Vitro Studies on Basella Rubra Different Extracts as Inhibitors of Key Enzymes Linked to Diabetes Mellitus. Pharmacogn. J. 2017, 9(1), 107–111.
   Google Scholar
• Kilari, B.; Netala, V. R.; Penchalaneni, J.; Kotatadi, V. S.; Tartte, V. Structural Elucidation, in Vitro Cytotoxicity Evaluation and Mechanism Study of Newly Secluded Bioactive Compound from the Leaf Extract of Basella Rubra L. Process Biochem. 2018, 67(175), 183.
   Google Scholar
• Sridevi, K.; Ravishankar, K.; Bhandhavi, P. P. In Vitro Antioxidant Activities of Ethanolic Seed Extract of Millettia Pinnata and Leaf Extract of Basella Alba. Int. J. Pharm. Chem. Biol. Sci. 2013, 3, 269–274.
   Google Scholar
• Suguna, J.; Thenmozhi, S.; Parimalam, K.; Kalaisaelvi, K.; Panner Selvam, K. Antimicrobial and Antioxidant Activity of the Leaf Extract Of. Basella Alba. Int J Pharm Pharm Sci. 2015, 3(2), 66–77.
   Google Scholar
• Salisu, T. F.; Okpuzor, J. E.; Jaja, S. I. Identification, Characterization and Quantification of Chemical Compounds in Selected Edible Leafy Vegetables. Ife J. Sci. 2019, 21(1), 215–227.
   Google Scholar
• Lin, S.; Lin, B.; Hsieh, W.; Ko, H.; Liu, C.; Chen, L.; Chiou, R. Y. Y. Structural Identification and Bioactivities of Red-violet Pigments Present in Basella Alba Fruits. J. Agric. Food Chem. 2010, 58, 10364–10372.
   PubMed Web of Science ®Google Scholar
• Sravan Kumar, S.; Manoj, P.; Shetty, N. P.; Prakash, M.; Giridhar, P. Characterization of Major Betalain Pigments- Gomphrenin, Betanin and Isobetanin from Basella Rubra L. Fruit and Evaluation of Efficacy as a Natural Colourant in Product (Ice Cream) Development. J. Food Sci. Technol. 2015, 52(8), 4994–5002.
   PubMed Web of Science ®Google Scholar
• Majumder, S.; Mukherjee, A. Wild Edible Plants Recorded from Hogalbaria Village of Nadia District, West Bengal, India. Indian J L Sci. 2015, 5, 63–74.
   Google Scholar
• Chau, C. F.; Wu, S. U. The Development of Regulations of Chinese Herbal Medicines for Both Medicinal and Food Uses. Trends Food Sci Techn. 2006, 17, 313–323.
   Web of Science ®Google Scholar
• Sushila, R.; Deepti, A.; Permender, R.; Madhavi, T.; Dharmender, R. Cytotoxic and Antibacterial Activity of Basella Alba Whole Plant: A Relatively Unexplored Plant. Pharmacologyonline. 2010, 3, 651–658.
   Google Scholar
• Kumar, V.; Bhat, Z. A.; Kumar, D.; Bohra, P.; Sheela, S. In-vitro Anti-inflammatory Activity of Leaf Extracts of Basella Alba L. Var. Alba. Int. J. Drug Dev. Res. 2011, 3, 176–179.
   Google Scholar
• Phadungkit, M.; Somdee, T.; Kangsadalampai, K. Phytochemical Screening, Antioxidant and Antimutagenic Activities of Selected Thai Edible Plant Extracts. J. Med. Plants Res. 2012, 6, 662–666.
   Google Scholar
• Baskaran, G.; Salvamani, S.; Ahmad, S. A.; Shaharuddin, N. A.; Pattiram, P. D.; Shukor, M. Y. HMG-Co-A Reductase Inhibitory Activity and Phytocomponent Investigation of Basella Alba Leaf Extract as a Treatment for Hypercholesterolemia. Drug Des. Devel. Ther. 2015, 9, 509–517.
   PubMed Web of Science ®Google Scholar
• Arokoyo, D. S.; Oyeyipo, I. P.; Du Plessis, S. S.; Chegou, N. N.; Aboua, Y. G. Modulation of Inflammatory Cytokins and Islet Morphology as Therapeutic Mechanisms of Basella Alba in Streptozotocin-induced Diabetic Rats. Toxicol. Res. 2018, 34(4), 325–332.
   PubMed Web of Science ®Google Scholar
• Nirmala, A.; Saroja, S.; Vasanthi, H. R. Lalitha. Hypoglycemic Effect of Basella Rubra in Streptozotocin-induced Diabetic Albino Rats. J Pharmacognosy Phytother. 2009, 1(2), 25–30.
   Google Scholar
• Nirmala, A.; Saroja, S.; Gayathri Devi, G. Antidiabetic Activity of Basella Rubra and Its Relationship with the Antioxidant Property. Br. Biotechnol. J. 2011, 1(1), 1–9.
   Google Scholar
• Deshpande, S.; Shah, G. B.; Deshpande, I.; Parmar, N. S. Antiulcer Activity of Aqueous Extract of Basella Rubra in Albino Rats. J. Nat. Remedies. 2003, 3(2), 212–214.
   Google Scholar
• Sravan Kumar, S.; Manoj, P.; Giridhar, P.; Shrivastava, R.; Bharadwaj, M. Fruit Extracts of Basella Rubra that are Rich in Bioactives and Betalains Exhibited Antioxidant Activity and Cytotoxicity against Human Cervical Carcinoma Cells. J. Funct. Foods. 2015, 15, 509–515.
   Web of Science ®Google Scholar
• Cooper, D. A.;. Carotenoids in Health and Diseases: Recent Scientific Evaluations, Research Recommendations and the Consumer. J. Nutr. 2004, 134, 221S–224S.
   PubMed Web of Science ®Google Scholar
• Baysal, T.; Ersus, S.; Starmans, A. J. Supercritical CO2 Extraction of β-carotene and Lycopene from Tomato Paste Waste. J. Agric. Food Chem. 2000, 48, 5507–5511.
   PubMed Web of Science ®Google Scholar
• Salgado-Roman, M.; Botello-Alvarez, E.; Rico-Martinez, R.; Navarrete-Bolanos, J. L. Enzymatic Treatment to Improve Extraction of Capsaicinoids and Carotenoids from Chili (Capsicum Annum) Fruits. J. Agric. Food Chem. 2008, 56(21), 10012–10018.
   PubMed Web of Science ®Google Scholar
• Mai, H. C.; Truong, V.; Debarte, F. Optimization of Enzyme-assisted Extraction of Oil Rich in Carotenoids from Gac Fruit (Momordica Cochinchinensis Spreng). Food Technol. Biotechnol. 2013, 51(4), 488–499.
   Web of Science ®Google Scholar
• Larsen, E.; Christensen, L. P. Simple Saponification Method for the Quantitative Determination of Carotenoids in Green Vegetables. J. Agric. Food Chem. 2005, 53(17), 6598–6602.
   PubMed Web of Science ®Google Scholar
• Biehler, E.; Mayer, F.; Hoffmann, L.; Krause, E.; Bohn, T. Comparison of 3 Spectrophotometric Methods for Carotenoids Determination in Frequently Consumed Fruits and Vegetables. J. Food Sci. 2010, 75(1), C55–C61.
   PubMed Web of Science ®Google Scholar
• Benzie, I. F. F.; Szeto, Y. T.; Strain, J. J.; Tomlinson, B. Consumption of Green Tea Causes Rapid Increase in Plasma Antioxidant Power in Humans. Nutr. Cancer. 1999, 34(1), 83–87.
   PubMed Web of Science ®Google Scholar
• Levites, Y.; Weinreb, O.; Maor, G.; Youdin, M. B. H. Mandel. Green Tea Polyphenol (̶) epigallocatechin 3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- induces dopaminergic neurodegeneration. J. Neurochem. 2001, 78, 1073–1082.
   PubMed Web of Science ®Google Scholar
• Bagchi, D.; Sen, C. K.; Ray, S. D.; Das, D. K.; Bagchi, M.; Preus, H. G.; Vinson, J. A. Molecular Mechanisms of Cardioprotection by a Novel Grape Seed Proanthocyanidin Extract. Mutat. Res. 2003, 9462, 1–11.
   Google Scholar
• Rietveld, A.; Wiseman, S. Antioxidant Effects of Tea: Evidence from Human Clinical Trials. J. Nutr. 2003, 133(10), 3285S–3292S.
   PubMed Web of Science ®Google Scholar
• Yi, W.; Akoh, C. C.; Fisher, J.; Krewer, G. Effects of Phenolic Compounds in Blueberries and Muscadine Grapes on HepG2 Cell Viability and Apoptosis. Food Res. Int. 2006, 39, 628–638.
   Web of Science ®Google Scholar
• Garcia-Salas, P.; Morales-Soto, A.; Segura-Carretero, A.; Fernández-Gutiérrez, A. Phenolic Compound-extraction Systems for Fruit and Vegetable Samples. Molecules. 2010, 15, 8813–8826.
   PubMed Web of Science ®Google Scholar
• Davidov-Pardo, G.; Marn-Arroyo, M. R. A. I. Stability of Polyphenolic Extracts from Grape Seeds after Thermal Treatments. Eur. Food Res. Technol. 2011, 232, 211–220.
   Web of Science ®Google Scholar
• Biesaga, M.; Pyrzynska, K. Stability of Bioactive Polyphenols from Honey during Different Extraction Methods. Food Chem. 2013, 136(1), 46–54.
   PubMed Web of Science ®Google Scholar
• Sowbhagya, H. B.; Chitra, V. N. Enzyme – Assisted Extraction of Flavorings and Colorants from Plant Materials. Crit. Rev. Food Sci. Nutr. 2010, 50, 146–161.
   PubMed Web of Science ®Google Scholar
• Cinar, I.;. Effects of Cellulase and Pectinase Concentrations on the Colour Yield of Enzyme Extracted Plant Carotenoids. Process Biochem. 2005, 40, 945–949.
   Web of Science ®Google Scholar
• Puri, M.; Sharma, D.; Barrow, C. J. Enzyme-assisted Extraction of Bioactives from Plants. Trends Biotechnol. 2012, 30, 37–44.
   PubMed Web of Science ®Google Scholar
• Zuorro, A.; Lavecchia, R. Mild Enzymatic Method for the Extraction of Lycopene from Tomato Paste. Biotechnol. Biotechnol. Equip. 2010, (24), 1854–1857.
   Web of Science ®Google Scholar
• Kammerer, D.; Claus, A.; Schieber, A.; Carle, R. A Novel Process for the Recovery of Polyphenols from Grape (Vitis Vinifera L.) Pomace. J. Food Sci. 2005, 70, C157–C163.
   Web of Science ®Google Scholar
• Kyriakopoulou, K.; Papadaki, S.; Krokida, M. Life Cycle Analysis of β-carotene Extraction Techniques. J. Food Engg. 2015, 167(A), 51–58.
   Google Scholar
• Dey, S.; Rathod, V. K. Ultrasound Assisted Extraction of β-carotene from Spirulina Platensis. Ultrason Sonochem. 2013, 20(1), 271–276.
   PubMed Web of Science ®Google Scholar
• Li, Y.; Fabiano-Tixier, A. S.; Tomao, V.; Cravotto, G.; Chemat, F. Green Ultrasound-assisted Extraction of Carotenoids Based on the Bio-refinery Concept Using Sunflower Oil as an Alternative Solvent. Ultrason. Sonochem. 2013, 20, 12–18.
   PubMed Web of Science ®Google Scholar
• Maran, J. P.; Priya, B. Natural Pigments Extraction from Basella Rubra L. Fruits by Ultrasound-Assisted Extraction Combined with Box-Behnken Response Surface Design. Sep. Sci. Technol. 2015, 50(10), 1532–1540.
   Web of Science ®Google Scholar
• Rodrigues, S.; Fernandes, F. A. N.; Brito, E. S.; Soura, A. D.; Narain, N. Ultrasound Extraction of Phenolics and Anthocyanins from Jabuticaba Peel. Ind. Crops Prod. 2015, 69, 400–407.
   Web of Science ®Google Scholar
• Kaufmann, B.; Christine, P. Recent Extraction Techniques for Natural Products: Microwave-assisted Extraction and Pressurized Solvent Extraction. Phytochem. Anal. 2002, 13, 105–113.
   PubMed Web of Science ®Google Scholar
• Delazar, A.; Nahar, L.; Hamedeyazdan, S.; Sarker, S. D. Microwave-assisted Extraction in Natural Products Isolation. Methods Mol. Biol. 2012, 864, 89–115.
   PubMedGoogle Scholar
• Sinhaa, K.; Chowdurya, S.; Sahaa, P. D.; Datta, S. Modeling of Microwave-assisted Extraction of Natural Dye from Seeds of Bixa Orellana (Annatto) Using Response Surface Methodology (RSM) and Artificial Neural Network (ANN). Ind. Crops Prod. 2013, 41, 165–171.
   Web of Science ®Google Scholar
• Maran, J. P.; Sivakumara, V.; Thirugnanasambandhama, K.; Sridhar, R. Optimization of Microwave Assisted Extraction of Pectin from Orange Peel. Carbohydr. Polym. 2013, 97, 703–709.
   PubMed Web of Science ®Google Scholar
• Garofulic, I. E.; Dragovic-Uzelac, V.; RezekJambrak, A.; Jukic, M. The Effect of Microwave Assisted Extraction on the Isolation of Anthocyanins and Phenolic Acids from Sour Cherry Marasca (Prunus Cerasus Var. Marasca). J. Food Eng. 2013, 117, 437–442.
   Web of Science ®Google Scholar
• Azmir, J.; Zaidul, I. S. M.; Rahman, M. M.; Sharif, K. M.; Mohamed, A. F. SahenA.; Jahurul, M. H. A.; Ghafoor, K. N.; Norulaini, A. N.; Omar A. K. M. Techniques for Extraction of Bioactive Compounds from Plant Materials: A Review. J. Food Eng. 2013, 117, 426–436.
   Web of Science ®Google Scholar
• Durante, M.; Lenucci, M. S.; Mita, G. Supercritical Carbon Dioxide Extraction of Carotenoids from Pumpkin (Cucurbita Spp.): A Review. Int. J. Mol. Sci. 2014, 15, 6725–6740.
   PubMed Web of Science ®Google Scholar
• Durante, M.; Lenucci, M. S.; D’Amico, L.; Piro, G.; Mita, G. Effect of Drying and Co-matrix Addition on the Yield and Quality of Supercritical CO2 Extracted Pumpkin (Cucurbita Moschata Duch.) Oil. Food Chem. 2014, 148, 314–320.
   PubMed Web of Science ®Google Scholar
• Shi, J.; Yi, C.; Ye, X.; Xue, S.; Jiang, Y.; Ma, Y.; Liu, D. Effects of Supercritical CO2 Fluid Parameters on Chemical Composition and Yield of Carotenoids Extracted from Pumpkin. LWT-Food Sci. Technol. 2010, 43, 39–44.
   Web of Science ®Google Scholar
• Reverchon, E.; de Marco, I. Supercritical Fluid Extraction and Fractionation of Natural Matter. J. Supercrit. Fluids. 2006, 38, 146–166.
   Web of Science ®Google Scholar
• Macias-Sanchez, M. D.; Mantell, C.; Rodriguez, M.; Martinez de la Ossa, E.; Lubian, L. M.; Montero, O. Supercritical Fluid Extraction of Carotenoids and Chlorophyll a from Nannochloropsis Gaditana. J. Food Eng. 2005, 66, 245–251.
   Web of Science ®Google Scholar
• Raut, P.; Bhosle, D.; Janghel, A.; Deo, S.; Verma, C.; Kumar, S. S.; Agrawal, M.; Amit, N.; Sharma, M.; Giri, T.; et al. Ajazuddin.; Alexander, A. Emerging Pressurized Liquid Extraction (PLE) Techniques as an Innovative Green Technologies for the Effective Extraction of the Active Phytopharmaceuticals. Res J. Pharm Tech. 2015, 8(6), 800–810.
   Google Scholar
• Machado, A. P. D. F.; Pasquel-Reategui, J.; Barbero, G. F.; Martinez, J. Pressurized Liquid Extraction of Bioactive Compounds from Blackberry (Rubus Fruticosus L.) Residues: A Comparison with Conventional Methods. Food Res. Int. 2015, 77(3), 675–678.
   Google Scholar
• Howard, L.; Pandjaitan, N. Pressurized Liquid Extraction of Flavonoids from Spinach. J. Food Sci. 2008, 73(3), C151–C157.
   PubMed Web of Science ®Google Scholar
• Putnik, P.; Barba, F. J.; Spanic, I.; Zoric, Z.; Dragovic-Uzelac, V.; Kovacevic, D. B. Green Extraction Approach for the Recovery of Polyphenols from Croatian Olive Leaves (Oleae Uropea). Food Bioprod. Process. 2017, 106, 19–28.
   Web of Science ®Google Scholar
• Ordonez-Santos, L. E.; Pinzon-Zarate, L. X.; Gonzalez-Salcedo, L. O. Optimization of Ultrasonic-assisted Extraction of Total Carotenoids from Peach Palm Fruit (Bactris Gasipaes) By-products with Sunflower Oil Using Response Surface Methodology. Ultrason. Sonochem. 2015, 27, 560–566.
   PubMed Web of Science ®Google Scholar
• Hiranvarachat, B.; Devahastin, S. Enhancement of Microwave-assisted Extraction via Intermittent Radiation: Extraction of Carotenoids from Carrot Peels. J. Food Eng. 2014, 126, 17–26.
   Web of Science ®Google Scholar
• Dordevic, V.; Balanc, B.; Belscak-Cvitanovic, A.; Levic, S.; Trifkovic, K.; Kalusevic, A.; Kostic, I.; Komes, D.; Bugarski, B.; Nedovic, V. Trends in Encapsulation Technologies for Delivery of Food Bioactive Compounds. Food Eng. Rev. 2015, 7, 452–490.
   Web of Science ®Google Scholar
• Singthong, J.; Oonsivilai, R. Oonmetta-Aree.; Ningsanond, S. Bioactive Compounds and Encapsulation of Yanang (Tiliacora Triandra) Leaves. Afr. J. Tradit. Complement. Altern. Med. 2014, 11(3), 76–84.
   PubMedGoogle Scholar
• Rascon, M. P.; Beristain, C. I.; Garcia, H. S.; Salgado, M. A. Carotenoid Retention and Storage Stability of Spray-dried Encapsulated Paprika Oleoresin Using Gum Arabic and Soy Protein Isolate as Wall Materials. LWT – Food Sci. Technol. 2011, 44, 549–557.
   Web of Science ®Google Scholar
• Nunes, I. L.; Mercadante, A. Z. Encapsulation of Lycopene Using Spray Drying and Molecular Inclusion Processes. Braz. Arch. Biol. Technol. 2007, 50, 893–900.
   Web of Science ®Google Scholar
• Zhang, L.; Mouand, D.; Du, Y. Procyanidins: Extraction and Micro- Encapsulation. J. Sci. Food Agric. 2007, 87, 2192–2197.
   Web of Science ®Google Scholar
• Chiou; Langrish. Development and Characterisation of Novel Nutraceuticals with Spray Drying Technology. J. Food Eng. 2007, 82, 84–91.
   Web of Science ®Google Scholar
• Airouyuwa, J. O.; Kaewmanee, T. Microencapsulation of Moringa Oliefera Leaf Extracts with Vegetable Protein as Wall Material. Food Sci. Technol. Int. 2019. DOI: 10.1177/1082013219842469.
   Web of Science ®Google Scholar
• Nantitanon, W.; Yotsawimonwat, S.; Okonogi, S. Factors Influencing Antioxidant Activities and Total Phenolic Content of Guava Leaf Extract. LWT-Food Sci. Technol. 2010, 43(7), 1095–1103.
   Web of Science ®Google Scholar
• Fernandes, M. R. V.; Kabeya, L. M.; Souza, C. R. F.; Massarioli, A. P.; Alencar, S. M.; Oliveira, W. P. Antioxidant Activity of Spray-dried Extracts of Psidium Guajava Leaves. J. Food Res. 2018, 7(4), 141–148.
   Google Scholar
• Sravan Kumar, S.; Chauhan, A. S.; Giridhar, P. Nanoliposomal Encapsulation Mediated Enhancement of Betalain Stability: Characterization, Storage Stability and Antioxidant Activity of Basella Rubra L. Fruits for Its Applications in Vegan Gummy Candies. Food Chem. 2020, 333, 127442.
   PubMed Web of Science ®Google Scholar
• Sravan Kumar, S.; Giridhar, P. Stabilization of Bioactive Betalain Pigment from Fruits of Basella Rubra L. Through Maltodextrin Encapsulation. Madridge J. Food Technol. 2017, 2(1), 73–77.
   Google Scholar
• Hasler, M. C.;. Functional Foods: Benefits, Concerns and challenges—A Position Paper from the American Council on Science and Health. J. Nutr. 2002, 132, 3772–3781.
   PubMed Web of Science ®Google Scholar
• Sravan Kumar, S.; Arya, M.; Chauhan, A. S.; Giridhar, P. Basella Rubra Fruit Juice Betalains as a Colorant in Food Model Systems and Shelf-life Studies to Determine Their Realistic Usability. J. Food Process. Preserv. 2020, e14595. DOI: 10.1111/jfpp.14595.
   Web of Science ®Google Scholar
• Reddy, V.; Urooj, A.; Kumar, A. Evaluation of Antioxidant Activity of Some Plant Extracts and Their Application in Biscuits. Food Chem. 2005, 90, 317–321.
   Web of Science ®Google Scholar
• Saini, R. K.; Shetty, N. P.; Prakash, M.; Giridhar, P. Effect of Dehydration Methods on Retention of Carotenoids. Tocopherols, Ascorbic Acid and Antioxidant Activity in Moringa Oleifera Leaves and Preparation of a RTE Product. J. Food Sci. Technol. 2014, 51(9), 2176–2182.
   PubMed Web of Science ®Google Scholar
• Jayswal, V. B.; Patel, V. H.; Dave, N. R. Effect of Incorporation of Fresh Basella Alba Leaves on Sensory Attributes and Antioxidant Potential of a Traditional Indian Product ‘Biwadi’. Int. J. Pure Appl. Biosci. 2019, 7(1), 425–435.
   Google Scholar
• Akindele, O.; Gbadamosi, O.; Taiwo, K.; Oyedele, D. J.; Adebooye, C. Proximate, Mineral, Sensory Evaluations and Shelf Stability of Chinchin Enriched with Ugu and Indian Spinach Vegetables. Int J Biochem Res Rev. 2017, 18(4), 1–14.
   Google Scholar
• Amorim-Carrilho, K. T.; Cepeda, A.; Fente, C.; Regal, P. Review of Methods for Analysis of Carotenoids. Trends Analyt Chem. 2014, 56, 49–73.
   Web of Science ®Google Scholar
• Capozzi, F.; Foodomics:, B. A. A New Comprehensive Approach to Food and Nutrition. Genes Nutr. 2013, 8, 1–4.
   PubMed Web of Science ®Google Scholar
• Ibanez, C.; Valdes, A.; Garcia-Canas, V.; Simo, C.; Celebier, M.; Rocamora-Reverte, L.; Gomez-Martinez,; Herrero, M.; Castro-Puvana, M.; Segura-Carretero, A.; et al. Global Foodomics Strategy to Investigate the Health Benefits of Dietary Constituents. J. Chromatogr. A. 2012, 1248, 139–153.
   PubMed Web of Science ®Google Scholar