The Quest for Phenolic Compounds from Seaweed: Nutrition, Biological Activities and Applications

References

• Sobuj, M. K. A.; Islam, M. A.; Haque, M. A.; Islam, M. M.; Alam, M. J.; Rafiquzzaman, S. Evaluation of Bioactive Chemical Composition, Phenolic, and Antioxidant Profiling of Different Crude Extracts of Sargassum Coriifolium and Hypnea Pannosa Seaweeds. J. Food Meas. Charact. 2021, 15(2), 1653.
   Web of Science ®Google Scholar
• Mac Monagail, M.; Cornish, L.; Morrison, L.; Araújo, R.; Critchley, A. Sustainable Harvesting of Wild Seaweed Resources. Eur. J. Phycol. 2017, 52(4), 371.
   Web of Science ®Google Scholar
• Mouritsen, O. G. Seaweeds: Edible, Available, and Sustainable; Chicago IL 60637: University of Chicago Press, 2013.
   Google Scholar
• Titlyanov, E., and Titlyanova, T. Seaweed Cultivation: Methods and Problems. Russ. J. Mar. Biol. 2010, 36(4), 227.
   Web of Science ®Google Scholar
• Msuya, F. E.; Bolton, J.; Pascal, F.; Narrain, K.; Nyonje, B.; Cottier-Cook, E. J. Seaweed Farming in Africa: Current Status and Future Potential. J. Appl. Phycol. 2022, 34(2), 985–1005. DOI: 10.1007/s10811-021-02676-w.
   Web of Science ®Google Scholar
• Arias-Echeverri, J. P.; Zapata-Ramírez, P. A.; Ramírez-Carmona, M.; Rendón-Castrillón, L.; Ocampo-López, C. Present and Future of Seaweed Cultivation and Its Applications in Colombia. 2022, 10(2), 243.
   Google Scholar
• Hasselström, L.; Visch, W.; Gröndahl, F.; Nylund, G. M.; Pavia, H. The Impact of Seaweed Cultivation on Ecosystem Services - a Case Study from the West Coast of Sweden. Mar. Pollut. Bull. 2018, 133, 53. DOI: 10.1016/j.marpolbul.2018.05.005.
   PubMed Web of Science ®Google Scholar
• Day, L.; Seymour, R. B.; Pitts, K. F.; Konczak, I.; Lundin, L. Incorporation of Functional Ingredients into Foods. Trends Food Sci. Technol. 2009, 20(9), 388. DOI: 10.1016/j.tifs.2008.05.002.
   Web of Science ®Google Scholar
• Peñalver, R.; Lorenzo, J. M.; Ros, G.; Amarowicz, R.; Pateiro, M.; Nieto, G. J. M. D. Seaweeds as a Functional Ingredient for a Healthy Diet. Mar. Drugs 2020, 18(6), 301.
   PubMed Web of Science ®Google Scholar
• Getachew, A. T.; Jacobsen, C.; Holdt, S. L. Emerging Technologies for the Extraction of Marine Phenolics: Opportunities and Challenges. Mar. Drugs. 2020, 18(8), 389. DOI: 10.3390/md18080389.
   PubMed Web of Science ®Google Scholar
• Hardjani, D. K.; Suantika, G.; Aditiawati, P. Nutritional Profile of Red Seaweed Kappaphycus Alvarezii After Fermentation Using Saccharomyces Cerevisiae as a Feed Supplement for White Shrimp Litopenaeus Vannamei Nutritional Profile of Fermented Red Seaweed. J. Pure Appl. Microbiol. 2017, 11(4), 1637.
   Google Scholar
• Siddique, M.; Khan, M.; Bhuiyan, M. Nutritional Composition and Amino Acid Profile of a Sub-Tropical Red Seaweed Gelidium Pusillum Collected from St. Martin’s Island, Bangladesh. Int. Food Res. J. 2013, 20(5), 2287.
   Google Scholar
• Polat, S.; Trif, M.; Rusu, A.; Simat, V.; Cagalj, M.; Alak, G.; Meral, R.; Ozogul, Y.; Polat, A., and Ozogul, F. Recent Advances in Industrial Applications of Seaweeds. Crit. Rev. Food Sci. Nutr. 2021, 1, 1–30.
   Google Scholar
• Gattuso, J.P., and Hansson, L. Ocean Acidification; United States Of America: Oxford university press, 2011.
   Google Scholar
• Marinho-Soriano, E.; Fonseca, P.; Carneiro, M.; Moreira, W. J. B. T. Seasonal Variation in the Chemical Composition of Two Tropical Seaweeds. Bioresour. Technol. 2006, 97(18), 2402.
   PubMed Web of Science ®Google Scholar
• Garcia-Vaquero, M.; Rajauria, G.; Miranda, M.; Sweeney, T.; Lopez-Alonso, M., and O’-Doherty, J. Seasonal Variation of the Proximate Composition, Mineral Content, Fatty Acid Profiles and Other Phytochemical Constituents of Selected Brown Macroalgae. Mar. Drugs 2021, 19(4), 204.
   PubMed Web of Science ®Google Scholar
• Cotas, J.; Leandro, A.; Monteiro, P.; Pacheco, D.; Figueirinha, A.; Goncalves, A. M. M.; da Silva, G. J.; Pereira, L. Seaweed Phenolics: From Extraction to Applications. Mar. Drugs. 2020, 18(8), 384. DOI: 10.3390/md18080384.
   PubMed Web of Science ®Google Scholar
• Cotas, J.; Pacheco, D.; Gonçalves, A. M.; Silva, P.; Carvalho, L. G.; Pereira, L. Seaweeds’ Nutraceutical and Biomedical Potential in Cancer Therapy: A Concise Review. J. Cancer Metastasis and Treat. 2021, 7, 13.
   Google Scholar
• Paiva, L.; Lima, E.; Neto, A. I.; Marcone, M.; Baptista, J. Nutritional and Functional Bioactivity Value of Selected Azorean Macroalgae: Ulva Compressa, Ulva Rigida, Gelidium Microdon, and Pterocladiella Capillacea. J. Food Sci. 2017, 82(7), 1757. DOI: 10.1111/1750-3841.13778.
   PubMed Web of Science ®Google Scholar
• Rioux, L.-E.; Beaulieu, L.; Turgeon, S. L. Seaweeds: A Traditional Ingredients for New Gastronomic Sensation. Food Hydrocolloids. 2017, 68, 255. DOI: 10.1016/j.foodhyd.2017.02.005.
   Web of Science ®Google Scholar
• Gupta, S.; Abu-Ghannam, N. Recent Developments in the Application of Seaweeds or Seaweed Extracts as a Means for Enhancing the Safety and Quality Attributes of Foods. Innov. Food Sci. Emerg. Technol. 2011, 12(4), 600. DOI: 10.1016/j.ifset.2011.07.004.
   Web of Science ®Google Scholar
• Bixler, H. J.; Porse, H. A Decade of Change in the Seaweed Hydrocolloids Industry. J. Appl. Phycol. 2011, 23(3), 321.
   Web of Science ®Google Scholar
• . Illera-Vives, M.; Seoane Labandeira, S.; Fernández-Labrada, M., and López-Mosquera, M. E. Chapter 19 - Agricultural Uses of Seaweed. In Sustainable Seaweed Technologies; Torres, M.D., Kraan, S., and Dominguez, H., Eds.; Radarweg 29, PO Box 211, 1000 AE Amsterdam, Netherlands: Elsevier, 2020; pp 591.
   Google Scholar
• Rajapakse, N.; Kim, S. K. Nutritional and Digestive Health Benefits of Seaweed. Adv. Food Nutr. Res. 2011, 64, 17.
   PubMedGoogle Scholar
• Fukuda, S.; Saito, H.; Nakaji, S.; Yamada, M.; Ebine, N.; Tsushima, E.; Oka, E.; Kumeta, K.; Tsukamoto, T.; Tokunaga, S. Pattern of Dietary Fiber Intake Among the Japanese General Population. Eur. J. Clin. Nutr. 2007, 61(1), 99.
   PubMed Web of Science ®Google Scholar
• Kumar, Y.; Tarafdar, A., and Badgujar, P. Seaweed as a Source of Natural Antioxidants: Therapeutic Activity and Food Applications. J. Food Qual. 2021, 2021, 1–17.
   Web of Science ®Google Scholar
• Pati, M. P.; Sharma, S.; Nayak, L.; Panda, C. R. Uses of Seaweed and Its Application to Human Welfare: A Review. Int. J. Pharm. Pharm. Sci. 2016, 8, 12.
   Google Scholar
• Jang, S.-S.; Shirai, Y.; Uchida, M., and Wakisaka, M. Production of Mono Sugar from Acid Hydrolysis of Seaweed. African Journal of Biotechnology. 2012, 11(8), 1953–1963.
   Google Scholar
• Stiger-Pouvreau, V.; Bourgougnon, N., and Deslandes, E. Carbohydrates from Seaweeds. In Seaweed in Health and Disease Prevention; Fleurence, Joel, Levine, Ira; Cambridge, Massachusetts: Elsevier, 2016; pp 223.
   Google Scholar
• Jimenez-Escrig, A.; Goni Cambrodon, I. Nutritional Evaluation and Physiological Effects of Edible Seaweeds. Arch. Latinoam. Nutr. 1999, 49(2), 114.
   PubMed Web of Science ®Google Scholar
• García-Vaquero, M.; Rajauria, G.; O’-Doherty, J. V.; Sweeney, T. Polysaccharides from Macroalgae: Recent Advances, Innovative Technologies and Challenges in Extraction and Purification. Food Res. Int. 2017, 99, 1011.
   PubMed Web of Science ®Google Scholar
• Pereira, L. Biological and Therapeutic Properties of the Seaweed Polysaccharides. Int. Biol. Rev. 2018, 2(2),1–50.
   Google Scholar
• Honya, M.; Mori, H.; Anzai, M.; Araki, Y., and Nisizawa, K., Monthly Changes in the Content of Fucans, Their Constituent Sugars and Sulphate in Cultured Laminaria Japonica. Sixteenth International Seaweed Symposium Cebu City, Philippines, Springer, 1999; pp 411.
   Google Scholar
• Peinado, I.; Girón, J.; Koutsidis, G.; Ames, J. Chemical Composition, Antioxidant Activity and Sensory Evaluation of Five Different Species of Brown Edible Seaweeds. Food Res. Int. 2014, 66, 36.
   Web of Science ®Google Scholar
• Fleurence, J. Seaweed Proteins: Biochemical, Nutritional Aspects and Potential Uses. Trends Food Sci. Technol. 1999, 10(1), 25. DOI: 10.1016/S0924-2244(99)00015-1.
   Web of Science ®Google Scholar
• Fleurence, J.; Morançais, M., and Dumay, J. Seaweed Proteins. In Proteins in Food Processing Y. Yada, Rickey; Duxford, CB22 4QH, United Kingdom: Elsevier. 2018; pp 245.
   Google Scholar
• Abdel-Fattah, A., and Sary, H. Selective Isolation of Glycoprotein Materials from the Green Seaweed Ulva Lactuca. Pak. J. Biochem. Mol. Biol. 1987, 20(2–Jan), 61.
   Google Scholar
• Machado, M.; Machado, S.; Pimentel, F. B.; Freitas, V.; Alves, R. C.; Oliveira, M. J. F. Amino Acid Profile and Protein Quality Assessment of Macroalgae Produced in an Integrated Multi-Trophic Aquaculture System. Foods 2020, 9(10), 1382.
   PubMed Web of Science ®Google Scholar
• Dawczynski, C.; Schubert, R.; Jahreis, G. Amino Acids, Fatty Acids, and Dietary Fibre in Edible Seaweed Products. Food Chem. 2007, 103(3), 891.
   Web of Science ®Google Scholar
• Pangestuti, R.; Kim, S.-K. Chapter 6 - Seaweed Proteins, Peptides, and Amino Acids. In Seaweed Sustainability; Tiwari, B.K. and Troy, D.J., Eds.; Academic Press: San Diego, 2015; pp 125.
   Google Scholar
• Shuuluka, D.; Bolton, J. J., and Anderson, R. J. J. Protein Content, Amino Acid Composition and Nitrogen-To-Protein Conversion Factors of Ulva Rigida and Ulva Capensis from Natural Populations and Ulva Lactuca from an Aquaculture System, in South Africa. J. Appl Phycol. 2013, 25(2), 677.
   Web of Science ®Google Scholar
• Cian, R. E.; Fajardo, M. A.; Alaiz, M.; Vioque, J.; González, R. J., and Drago, S. R. J. Nutrition, Chemical Composition, Nutritional and Antioxidant Properties of the Red Edible Seaweed Porphyra Columbina. Int. J. Food Sci. Nutr. 2014, 65(3), 299.
   PubMed Web of Science ®Google Scholar
• MacArtain, P.; Gill, C. I.; Brooks, M.; Campbell, R.; Rowland, I. R. Nutritional Value of Edible Seaweeds. Nutr. Rev. 2007, 65(12 Pt 1), 535. DOI: 10.1111/j.1753-4887.2007.tb00278.x.
   PubMed Web of Science ®Google Scholar
• Mabeau, S.; Fleurence, J. Seaweed in Food Products: Biochemical and Nutritional Aspects. Trends Food Sci. Technol. 1993, 4(4), 103.
   Web of Science ®Google Scholar
• Schmid, M.; Kraft, L. G. K.; van der Loos, L. M.; Kraft, G. T.; Virtue, P.; Nichols, P. D.; Hurd, C. L. Southern Australian Seaweeds: A Promising Resource for Omega-3 Fatty Acids. Food Chem. 2018, 265, 70. DOI: 10.1016/j.foodchem.2018.05.060.
   PubMed Web of Science ®Google Scholar
• Susanto, E.; Fahmi, A. S.; Abe, M.; Hosokawa, M.; Miyashita, K. Lipids, Fatty Acids, and Fucoxanthin Content from Temperate and Tropical Brown Seaweeds. Aquat. Procedia 2016, 7, 66.
   Google Scholar
• Chua, M. E.; Sio, M. C.; Sorongon, M. C.; Dy, J. S. Relationship of Dietary Intake of Omega-3 and Omega-6 Fatty Acids with Risk of Prostate Cancer Development: A Meta-Analysis of Prospective Studies and Review of Literature. Prostate Cancer. 2012, 2012, 826254. DOI: 10.1155/2012/826254.
   PubMedGoogle Scholar
• Gosch, B. J.; Magnusson, M.; Paul, N. A.; De Nys, R. Total Lipid and Fatty Acid Composition of Seaweeds for the Selection of Species for Oil‐based Biofuel and Bioproducts. GCB Bioenergy 2012, 4(6), 919.
   Google Scholar
• Kendel, M.; Wielgosz-Collin, G.; Bertrand, S.; Roussakis, C.; Bourgougnon, N., and Bedoux, G. Lipid Composition, Fatty Acids and Sterols in the Seaweeds Ulva Armoricana, and Solieria Chordalis from Brittany (France): An Analysis from Nutritional, Chemotaxonomic, and Antiproliferative Activity Perspectives. Mar. Drugs 2015, 13(9), 5606.
   PubMed Web of Science ®Google Scholar
• Mišurcová, L.; Ambrožová, J., and Samek, D. Chapter 27 - Seaweed Lipids as Nutraceuticals. In Advances in Food and Nutrition Research; Kim, S.-K., Ed.; Waltham, MA02451, USA: Academic Press: 2011; Vol. 64, pp 339.
   Google Scholar
• Miyashita, K.; Nishikawa, S.; Beppu, F.; Tsukui, T.; Abe, M.; Hosokawa, M. The Allenic Carotenoid Fucoxanthin, a Novel Marine Nutraceutical from Brown Seaweeds. J. Sci. Food Agric. 2011, 91(7), 1166. DOI: 10.1002/jsfa.4353.
   PubMed Web of Science ®Google Scholar
• Sánchez-Machado, D.; López-Cervantes, J.; Lopez-Hernandez, J.; Paseiro-Losada, P. Fatty Acids, Total Lipid, Protein and Ash Contents of Processed Edible Seaweeds. Food Chem. 2004, 85(3), 439.
   Web of Science ®Google Scholar
• Cherry, P.; O’-Hara, C.; Magee, P. J.; McSorley, E. M., and Allsopp, P. J. Risks and Benefits of Consuming Edible Seaweeds. Nut. Rev. 2019, 77(5), 307.
   PubMed Web of Science ®Google Scholar
• Watanabe, F.; Yabuta, Y.; Bito, T.; Teng, F. Vitamin B₁₂-Containing Plant Food Sources for Vegetarians. Nutrients. 2014, 6(5), 1861. DOI: 10.3390/nu6051861.
   PubMed Web of Science ®Google Scholar
• Ito, K.; Hori, K. Seaweed: Chemical Composition and Potential Food Uses. Food Revi Int. 1989, 5(1), 101.
   Google Scholar
• Mišurcová, L.; Machů, L., and Orsavová, J. Seaweed Minerals as Nutraceuticals. Advances in Food and Nutrition Research. 2011, 64, 371.
   PubMedGoogle Scholar
• Fleurence, J.; Morançais, M.; Dumay, J.; Decottignies, P.; Turpin, V.; Munier, M.; Garcia-Bueno, N.; Jaouen, P. What are the Prospects for Using Seaweed in Human Nutrition and for Marine Animals Raised Through Aquaculture? Trends Food Sci. Technol. 2012, 27(1), 57. DOI: 10.1016/j.tifs.2012.03.004.
   Web of Science ®Google Scholar
• Saranraj, P.; Behera, S. S., and Ray, R. C. Traditional Foods from Tropical Root and Tuber Crops: Innovations and Challenges. In Innovations in Traditional Foods. M. Galanakis, Charis; Duxford, CB22 4QH, United Kingdom: Elsevier, 2019; pp 159.
   Google Scholar
• Cotas, J.; Leandro, A.; Pacheco, D.; Goncalves, A. M. M.; Pereira, L. A Comprehensive Review of the Nutraceutical and Therapeutic Applications of Red Seaweeds (Rhodophyta). Life (Basel). 2020, 10(3), 19.
   PubMed Web of Science ®Google Scholar
• Padmanabhan, P.; Correa-Betanzo, J., and Paliyath, G. Berries and Related Fruits. In Encyclopedia of Food and Health; Caballero, B., Finglas, P.M., and Toldrá, F., Eds.; Academic Press: Oxford, 2016; pp 364.
   Google Scholar
• Pietta, P.; Minoggio, M.; Bramati, L. Plant Polyphenols: Structure, Occurrence and Bioactivity. Stud. Nat. Prod. Chem. 2003, 28, 257. Elsevier.
   Google Scholar
• Lomartire, S.; Cotas, J.; Pacheco, D.; Marques, J. C.; Pereira, L.; Gonçalves, A. M. M. Environmental Impact on Seaweed Phenolic Production and Activity: An Important Step for Compound Exploitation. Mar. Drugs 2021, 19(5), 245.
   PubMed Web of Science ®Google Scholar
• Agregán, R.; Munekata, P. E. S.; Franco, D.; Dominguez, R.; Carballo, J.; Lorenzo, J. M. Phenolic Compounds from Three Brown Seaweed Species Using LC-DAD–ESI-MS/MS. Food Res. Int. 2017, 99, 979. DOI: 10.1016/j.foodres.2017.03.043.
   PubMed Web of Science ®Google Scholar
• Rajauria, G.; Foley, B.; Abu-Ghannam, N. Identification and Characterization of Phenolic Antioxidant Compounds from Brown Irish Seaweed Himanthalia Elongata Using LC-DAD–ESI-MS/MS. Innov. Food Sci. Emerg. Technol. 2016, 37, 261. DOI: 10.1016/j.ifset.2016.02.005.
   Web of Science ®Google Scholar
• Rajauria, G. Optimization and Validation of Reverse Phase HPLC Method for Qualitative and Quantitative Assessment of Polyphenols in Seaweed. J. Pharm. Biomed. Anal. 2018, 148, 230. DOI: 10.1016/j.jpba.2017.10.002.
   PubMed Web of Science ®Google Scholar
• Pangestuti, R.; Getachew, A. T.; Siahaan, E. A.; Chun, B.-S. Characterization of Functional Materials Derived from Tropical Red Seaweed Hypnea Musciformis Produced by Subcritical Water Extraction Systems. J. Appl. Phycol. 2019, 31(4), 2517. DOI: 10.1007/s10811-019-1754-9.
   Web of Science ®Google Scholar
• Novoa, A. V.; Andrade-Wartha, E. R.; Linares, A. F.; Silva, A. M. D. O.; Genovese, M. I.; González, A. E. B.; Vuorela, P.; Costa, A., and Mancini-Filho, J. Antioxidant Activity and Possible Bioactive Components in Hydrophilic and Lipophilic Fractions from the Seaweed Halimeda Incrassata. Brazilian Journal of Pharmacognosy. 2011, 21, 53.
   Web of Science ®Google Scholar
• Hernández, I.; Alegre, L.; Van Breusegem, F.; Munné-Bosch, S. How Relevant are Flavonoids as Antioxidants in Plants? Trends Plant Sci. 2009, 14(3), 125.
   PubMed Web of Science ®Google Scholar
• Pelegrin, Y.; Freile, A., and Robledo, D. Bioactive Phenolic Compounds from Algae. In Bioactive Compounds from Marine Foods: Plants and Animal Sources. Hernandez-Ledesma, Blanca; 525 W. Van Buren st. Suite 1000, Chicago IL 60607: John Wiley & sons, Ltd, 2013; pp 113–129.
   Google Scholar
• Tanna, B.; Choudhary, B.; Mishra, A. Metabolite Profiling, Antioxidant, Scavenging and Anti-Proliferative Activities of Selected Tropical Green Seaweeds Reveal the Nutraceutical Potential of Caulerpa Spp. Algal Res. 2018, 36, 96.
   Google Scholar
• Mohy El-Din, S. M.; El-Ahwany, A. M. D. Bioactivity and Phytochemical Constituents of Marine Red Seaweeds (Jania Rubens, Corallina Mediterranea and Pterocladia Capillacea). J. Taibah Univ. Sci. 2016, 10(4), 471. DOI: 10.1016/j.jtusci.2015.06.004.
   Web of Science ®Google Scholar
• Santos, S. A. O.; Felix, R.; Pais, A. C. S.; Rocha, S. M.; Silvestre, A. J. D. The Quest for Phenolic Compounds from Macroalgae: A Review of Extraction and Identification Methodologies. Biomolecules. 2019, 9(12), 847. DOI: 10.3390/biom9120847.
   PubMed Web of Science ®Google Scholar
• Rajeshkumar, R., and Jeyaprakash, K.HPLC Analysis of Flavonoids in Acanthophora Specifera (Red Seaweed) Collected from Gulf of Mannar.International Journal of Science and Research (IJSR). 2015. 6(9), 69–72.
   Google Scholar
• Tanna, B.; Brahmbhatt, H. R.; Mishra, A. Phenolic, Flavonoid, and Amino Acid Compositions Reveal That Selected Tropical Seaweeds Have the Potential to Be Functional Food Ingredients. J. Food Process. Preserv. 2019, 43(12), e14266.
   Web of Science ®Google Scholar
• Yoshie-Stark, Y.; Hsieh, Y.-P., and Suzuki, T. Distribution of Flavonoids and Related Compounds from Seaweeds in Japan. Journal of Tokyo University of Fisheries . 2003, 89, 1.
   Google Scholar
• Rajan, D. K.; Mohan, K.; Zhang, S.; Ganesan, A. R. Dieckol: A Brown Algal Phlorotannin with Biological Potential. Biomed. Pharmacother. 2021, 142, 111988. DOI: 10.1016/j.biopha.2021.111988.
   PubMed Web of Science ®Google Scholar
• Gómez, I.; Huovinen, P. Brown Algal Phlorotannins: An Overview of Their Functional Roles. In Antarctic Seaweeds: Diversity, Adaptation and Ecosystem Services; Gómez, I. and Huovinen, P., Eds.; Springer International Publishing: Cham, 2020; pp 365.
   Google Scholar
• Targett, N. M.; Arnold, T. M. Minireview—predicting the Effects of Brown Algal Phlorotannins on Marine Herbivores in Tropical and Temperate Oceans. 1998, 34(2), 195.
   Google Scholar
• Imbs, T.; Zvyagintseva, T. Phlorotannins are Polyphenolic Metabolites of Brown Algae. Russ J. Mar. Biol. 2018, 44(4), 263.
   Web of Science ®Google Scholar
• Marinho, G. S.; Sørensen, A.-D.-M.; Safafar, H.; Pedersen, A. H.; Holdt, S. L. Antioxidant Content and Activity of the Seaweed Saccharina Latissima: A Seasonal Perspective. J. Appl. Phycol. 2019, 31(2), 1343. DOI: 10.1007/s10811-018-1650-8.
   Web of Science ®Google Scholar
• Rengasamy, K. R. R.; Mahomoodally, M. F.; Aumeeruddy, M. Z.; Zengin, G.; Xiao, J.; Kim, D. H. Bioactive Compounds in Seaweeds: An Overview of Their Biological Properties and Safety. Food Chem. Toxicol. 2020, 135, 111013. DOI: 10.1016/j.fct.2019.111013.
   PubMed Web of Science ®Google Scholar
• Negara, B.; Sohn, J. H.; Kim, J. S.; Choi, J. S. Effects of Phlorotannins on Organisms: Focus on the Safety, Toxicity, and Availability of Phlorotannins. Foods. 2021, 10(2), 452. DOI: 10.3390/foods10020452.
   PubMed Web of Science ®Google Scholar
• Mateos, R.; Perez-Correa, J. R.; Dominguez, H. Bioactive Properties of Marine Phenolics. Mar. Drugs. 2020, 18(10), 501. DOI: 10.3390/md18100501.
   PubMed Web of Science ®Google Scholar
• Rajasulochana, P.; Krishnamoorthy, P.; Dhamotharan, R. Isolation, Identification of Bromophenol Compound and Antibacterial Activity of Kappaphycus Sp. Int. J. Pharm. Biol. 2012, 3, 173.
   Google Scholar
• Cabrita, M. T.; Vale, C.; Rauter, A. P. Halogenated Compounds from Marine Algae. Mar. Drugs. 2010, 8(8), 2301. DOI: 10.3390/md8082301.
   PubMed Web of Science ®Google Scholar
• Liu, M.; Hansen, P. E.; Lin, X. Bromophenols in Marine Algae and Their Bioactivities. Mar. Drugs 2011, 9(7), 1273.
   PubMed Web of Science ®Google Scholar
• Bidleman, T. F.; Andersson, A.; Brugel, S.; Ericson, L.; Haglund, P.; Kupryianchyk, D.; Lau, D. C.; Liljelind, P.; Lundin, L.; Tysklind, A. J. E. S. P. Impacts, Bromoanisoles and Methoxylated Bromodiphenyl Ethers in Macroalgae from Nordic Coastal Regions. Environ. Sci. Processes Impacts 2019, 21(5), 881.
   PubMed Web of Science ®Google Scholar
• Mandrekar, V. K.; Gawas, U. B., and Majik, M. S. Chapter 13 - Brominated Molecules from Marine Algae and Their Pharmacological Importance. In Studies in Natural Products Chemistry; Attaur, R., Ed.; Radarweg 29, PO Box 211, 1000 AE Amsterdam, Netherlands: Elsevier, 2019; Vol. 61, pp 461.
   Google Scholar
• Machado, L.; Magnusson, M.; Paul, N. A.; Kinley, R.; de Nys, R.; Tomkins, N. Identification of Bioactives from the Red Seaweed Asparagopsis Taxiformis That Promote Antimethanogenic Activity in vitro. Journal Appl. Phycol. 2016, 28(5), 3117.
   Web of Science ®Google Scholar
• Hussain, E.; Wang, L.; Jiang, B.; Riaz, S.; Butt, G.; Shi, D. Components of Brown Seaweeds are Potential Candidate for Cancer Therapy-A Review. R. Soc. Chem. 2016, 10, C5RA23995H.
   Google Scholar
• Panzella, L.; Moccia, F.; Nasti, R.; Marzorati, S.; Verotta, L., and Napolitano, A. Bioactive Phenolic Compounds from Agri-Food Wastes: An Update on Green and Sustainable Extraction Methodologies. Front. Nutr. 2020, 7, 60.
   PubMed Web of Science ®Google Scholar
• Senthilkumar, K.; Manivasagan, P.; Venkatesan, J.; Kim, S.-K. Brown Seaweed Fucoidan: Biological Activity and Apoptosis, Growth Signaling Mechanism in Cancer. Int. J. Biol. Macromol. 2013, 60, 366. DOI: 10.1016/j.ijbiomac.2013.06.030.
   PubMed Web of Science ®Google Scholar
• Bray, F.; Ferlay, J.; Soerjomataram, I.; Siegel, R. L.; Torre, L. A.; Jemal, A. Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J. Clin. 2018, 68(6), 394. DOI: 10.3322/caac.21492.
   PubMed Web of Science ®Google Scholar
• Wang, L.-J.; Guo, C.-L.; Li, X.-Q.; Wang, S.-Y.; Jiang, B.; Zhao, Y.; Luo, J.; Xu, K.; Liu, H.; Guo, S.-J., et al. Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents Through the Ros-Mediated Apoptotic Pathway: Design. Synth. Biol. Eval. 2017, 15(11), 343.
   Google Scholar
• Guo, C. L.; Wang, L. J.; Zhao, Y.; Liu, H.; Li, X. Q.; Jiang, B.; Luo, J.; Guo, S. J.; Wu, N.; Shi, D. Y. A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated Pi3k/akt and the MAPK Signaling Pathway. Mar. Drugs. 2018, 16(2), 43. DOI: 10.3390/md16020043.
   PubMed Web of Science ®Google Scholar
• Guo, C.; Wang, L.; Zhao, Y.; Jiang, B.; Luo, J.; Shi, D. J. E.; Medicine, T. BOS‑93, a Novel Bromophenol Derivative, Induces Apoptosis and Autophagy in Human A549 Lung Cancer Cells via Pi3k/akt/mtor and MAPK Signaling Pathway. Exp. Ther. Med. 2019, 17(5), 3848.
   PubMed Web of Science ®Google Scholar
• Qi, X.; Liu, G.; Qiu, L.; Lin, X.; Liu, M. Marine Bromophenol Bis(2,3-Dibromo-4,5-Dihydroxybenzyl) Ether, Represses Angiogenesis in HUVEC Cells and in Zebrafish Embryos via Inhibiting the VEGF Signal Systems. Biomed. Pharmacother. 2015, 75, 58. DOI: 10.1016/j.biopha.2015.08.033.
   PubMed Web of Science ®Google Scholar
• He, Z.; Chen, Y.; Chen, Y.; Liu, H.; Yuan, G.; Fan, Y.; Chen, K. Optimization of the Microwave-Assisted Extraction of Phlorotannins from Saccharina Japonica Aresch and Evaluation of the Inhibitory Effects of Phlorotannin-Containing Extracts on HepG2 Cancer Cells. Chin. J. Oceanol. Limnol. 2013, 31(5), 1045.
   Web of Science ®Google Scholar
• Nwosu, F.; Morris, J.; Lund, V. A.; Stewart, D.; Ross, H. A.; McDougall, G. J. Anti-Proliferative and Potential Anti-Diabetic Effects of Phenolic-Rich Extracts from Edible Marine Algae. Food Chem. 2011, 126(3), 1006. DOI: 10.1016/j.foodchem.2010.11.111.
   Web of Science ®Google Scholar
• Henry, M.; Wilson, M.; Martin, O.; Ntevheleni, T.; Wilfred, T. Phlorotannins and a Sterol Isolated from a Brown Alga Ecklonia Maxima, and Their Cytotoxic Activity Against Selected Cancer Cell Lines HeLa, H157 and MCF7. Interdiscip. 2017, 2, 1.
   Google Scholar
• Thomas, N. V.; Kim, S. K. Potential Pharmacological Applications of Polyphenolic Derivatives from Marine Brown Algae. Environ. Toxicol. Pharmacol. 2011, 32(3), 325. DOI: 10.1016/j.etap.2011.09.004.
   PubMed Web of Science ®Google Scholar
• Matulja, D.; Vranješević, F.; Kolympadi Markovic, M.; Pavelić, S. K.; Marković, D. Anticancer Activities of Marine-Derived Phenolic Compounds and Their Derivatives. 2022, 27(4), 1449.
   Google Scholar
• Gunathilaka, T.; Keertihirathna, L. R.; Peiris, D. Advanced Pharmacological Uses of Marine Algae as an Anti-Diabetic Therapy. 2021.
   Google Scholar
• Sharifuddin, Y.; Chin, Y.-X.; Lim, P.-E.; Phang, S.-M. Potential Bioactive Compounds from Seaweed for Diabetes Management. Mar. Drugs 2015, 13(8), 5447.
   PubMed Web of Science ®Google Scholar
• Murugan, A. C.; Karim, M. R.; Yusoff, M. B. M.; Tan, S. H.; Asras, M. F. B. F.; Rashid, S. S. New Insights into Seaweed Polyphenols on Glucose Homeostasis. Pharm. Biol. 2015, 53(8), 1087.
   PubMed Web of Science ®Google Scholar
• Lin, X.; Liu, M. Bromophenols from Marine Algae with Potential Anti-Diabetic Activities. J. Ocean Univ. China. 2012, 11(4), 533. DOI: 10.1007/s11802-012-2109-1.
   Web of Science ®Google Scholar
• Mateos, R.; Pérez-Correa, J. R.; Domínguez, H. J. M. D. Bioactive Properties of Marine Phenolics. Mar. Drugs 2020, 18(10), 501.
   PubMed Web of Science ®Google Scholar
• Xu, Q.; Luo, J.; Wu, N.; Zhang, R.; Shi, D. BPN, a Marine-Derived PTP1B Inhibitor, Activates Insulin Signaling and Improves Insulin Resistance in C2C12 Myotubes. Int. J. Biol. Macromol. 2018, 106, 379. DOI: 10.1016/j.ijbiomac.2017.08.042.
   PubMed Web of Science ®Google Scholar
• Gunathilaka, T. L.; Samarakoon, K. W.; Ranasinghe, P.; Peiris, L. D. C. In-Vitro Antioxidant, Hypoglycemic Activity, and Identification of Bioactive Compounds in Phenol-Rich Extract from the Marine Red Algae Gracilaria Edulis (Gmelin) Silva. Molecules. 2019, 24(20), 3708. DOI: 10.3390/molecules24203708.
   PubMed Web of Science ®Google Scholar
• Lee, S. H.; Karadeniz, F.; Kim, M. M.; Kim, S. K. α‐Glucosidase and α‐amylase Inhibitory Activities of Phloroglucinal Derivatives from Edible Marine Brown Alga, Ecklonia Cava. J. Sci. Food Agric. 2009, 89(9), 1552.
   Web of Science ®Google Scholar
• Lee, S.-H.; Park, M.-H.; Heo, S.-J.; Kang, S.-M.; Ko, S.-C.; Han, J.-S.; Jeon, Y.-J.-J.-F. Dieckol Isolated from Ecklonia Cava Inhibits α-Glucosidase and α-Amylase in vitro and Alleviates Postprandial Hyperglycemia in Streptozotocin-Induced Diabetic Mice. Food Chem. Toxicol. 2010, 48(10), 2633.
   PubMed Web of Science ®Google Scholar
• Lee, H. A.; Lee, J. H.; Han, J. S. A Phlorotannin Constituent of Ecklonia Cava Alleviates Postprandial Hyperglycemia in Diabetic Mice. Pharm. Biol. 2017, 55(1), 1149. DOI: 10.1080/13880209.2017.1291693.
   PubMed Web of Science ®Google Scholar
• Lee, S.-H.; Jeon, Y.-J. Anti-Diabetic Effects of Brown Algae Derived Phlorotannins, Marine Polyphenols Through Diverse Mechanisms. Fitoterapia. 2013, 86, 129. DOI: 10.1016/j.fitote.2013.02.013.
   PubMed Web of Science ®Google Scholar
• Moon, H. E.; Islam, M. N.; Ahn, B. R.; Chowdhury, S. S.; Sohn, H. S.; Jung, H. A., and Choi, J. S. Protein Tyrosine Phosphatase 1B and α-Glucosidase Inhibitory Phlorotannins from Edible Brown Algae, Ecklonia Stolonifera Eisenia Bicyclis. Biosci. Biotechnol Biochem. 2011, 75 (8), 1472.
   PubMed Web of Science ®Google Scholar
• Yan, X.; Yang, C.; Lin, G.; Chen, Y.; Miao, S.; Liu, B.; Zhao, C. Antidiabetic Potential of Green Seaweed Enteromorpha Prolifera Flavonoids Regulating Insulin Signaling Pathway and Gut Microbiota in Type 2 Diabetic Mice. J. Food Sci. 2019, 84(1), 165. DOI: 10.1111/1750-3841.14415.
   PubMed Web of Science ®Google Scholar
• Pereira, L.; Valado, A. The Seaweed Diet in Prevention and Treatment of the Neurodegenerative Diseases. Mar. Drugs 2021, 19(3), 128.
   PubMed Web of Science ®Google Scholar
• Lomartire, S.; Goncalves, A. M. M. An Overview of Potential Seaweed-Derived Bioactive Compounds for Pharmaceutical Applications. Mar. Drugs. 2022, 20(2), 141. DOI: 10.3390/md20020141.
   PubMed Web of Science ®Google Scholar
• Myung, C. S.; Shin, H. C.; Bao, H. Y.; Yeo, S. J.; Lee, B. H.; Kang, J. S. Improvement of Memory by Dieckol and Phlorofucofuroeckol in Ethanol-Treated Mice: Possible Involvement of the Inhibition of Acetylcholinesterase. Arch. Pharm. Res. 2005, 28(6), 691. DOI: 10.1007/BF02969360.
   PubMed Web of Science ®Google Scholar
• Nho, J. A.; Shin, Y. S.; Jeong, H. R.; Cho, S.; Heo, H. J.; Kim, G. H.; Kim, D. O. Neuroprotective Effects of Phlorotannin-Rich Extract from Brown Seaweed Ecklonia Cava on Neuronal PC-12 and SH-SY5Y Cells with Oxidative Stress. J. Microbiol. Biotechnol. 2020, 30(3), 359. DOI: 10.4014/jmb.1910.10068.
   PubMed Web of Science ®Google Scholar
• Adhami, H.-R., and Sharafi, P. Can Marine Products Improve Alzheimer’s Disease. Journal of Sciences, Islamic Republic of Iran. 2020, 31(4), 321.
   Google Scholar
• Kim, A.-R.; Shin, T.-S.; Lee, M.-S.; Park, J.-Y.; Park, K.-E.; Yoon, N.-Y.; Kim, J.-S.; Choi, J.-S.; Jang, B.-C., and Byun, D., et al. Isolation and Identification of Phlorotannins from Ecklonia Stolonifera with Antioxidant and Anti-Inflammatory Properties. J. Agric. Food Chem. 2009, 57(9), 3483.
   PubMed Web of Science ®Google Scholar
• Shibata, T.; Ishimaru, K.; Kawaguchi, S.; Yoshikawa, H., and Hama, Y. Antioxidant Activities of Phlorotannins Isolated from Japanese Laminariaceae. Nineteenth International Seaweed Symposium; Kobe, Japan. Springer, 2007; pp 255.
   Google Scholar
• Paudel, P.; Park, S. E.; Seong, S. H.; Jung, H. A.; Choi, J. S. Bromophenols from Symphyocladia Latiuscula Target Human Monoamine Oxidase and Dopaminergic Receptors for the Management of Neurodegenerative Diseases. J. Agric. Food Chem. 2020, 68(8), 2426. DOI: 10.1021/acs.jafc.0c00007.
   PubMed Web of Science ®Google Scholar
• Barbosa, M.; Lopes, G.; Andrade, P. B.; Valentão, P. Bioprospecting of Brown Seaweeds for Biotechnological Applications: Phlorotannin Actions in Inflammation and Allergy Network. Trends Food Sci. Technol. 2019, 86, 153. DOI: 10.1016/j.tifs.2019.02.037.
   Web of Science ®Google Scholar
• Lagunoff, D.; Martin, T., and Read, G. Agents That Release Histamine from Mast Cells. Annu. Rev. Pharmacol. Toxicol. 1983, 23(1), 331.
   PubMedGoogle Scholar
• Vo, T.-S.; Ngo, D.-H.; Kim, S.-K. Marine Algae as a Potential Pharmaceutical Source for Anti-Allergic Therapeutics. Process Biochem. 2012, 47(3), 386.
   Web of Science ®Google Scholar
• Shim, S.-Y.; Choi, J.-S.; Byun, D.-S. Inhibitory Effects of Phloroglucinol Derivatives Isolated from Ecklonia Stolonifera on FcεRI Expression. Bioorg. Med. Chem. 2009, 17(13), 4734.
   PubMed Web of Science ®Google Scholar
• Li, Y.; Lee, S.-H.; Le, Q.-T.; Kim, M.-M.; Kim, S.-K. Anti-Allergic Effects of Phlorotannins on Histamine Release via Binding Inhibition Between IgE and FcεRI. J. Agric. Food. Chem. 2008, 56(24), 12073.
   PubMed Web of Science ®Google Scholar
• Matsui, T.; Ito, C.; Itoigawa, M.; Shibata, T. Three Phlorotannins from Sargassum Carpophyllum are Effective Against the Secretion of Allergic Mediators from Antigen-Stimulated Rat Basophilic Leukemia Cells. Food Chem. 2022, 377, 131992. DOI: 10.1016/j.foodchem.2021.131992.
   PubMed Web of Science ®Google Scholar
• Venkatesan, J.; Keekan, K. K.; Anil, S.; Bhatnagar, I., and Kim, S.-K. Phlorotannins. In Encyclopedia of Food Chemistry; Melton, Laurence, Shahidi, Fereidoon; Radarweg 29, PO Box 211, 1000 AE Amsterdam, Netherlands: Elsevier, 2019; pp 515.
   Google Scholar
• Lee, D. S.; Eom, S. H.; Jeong, S. Y.; Shin, H. J.; Je, J. Y.; Lee, E. W.; Chung, Y. H.; Kim, Y. M.; Kang, C. K.; Lee, M. S. Anti-Methicillin-Resistant Staphylococcus Aureus (MRSA) Substance from the Marine Bacterium Pseudomonas Sp. UJ-6. Environ. Toxicol. Pharmacol. 2013, 35(2), 171. DOI: 10.1016/j.etap.2012.11.011.
   PubMed Web of Science ®Google Scholar
• Lee, D.-S.; Kang, M.-S.; Hwang, H.-J.; Eom, S.-H.; Yang, J.-Y.; Lee, M.-S.; Lee, W.-J.; Jeon, Y.-J.; Choi, J.-S.; Kim, Y.-M. Synergistic Effect Between Dieckol from Ecklonia Stolonifera and β-Lactams Against Methicillin-Resistant Staphylococcus Aureus. Biotechnol. Bioprocess Eng. 2008, 13(6), 758.
   Web of Science ®Google Scholar
• Eom, S. H.; Kim, D. H.; Lee, S. H.; Yoon, N. Y.; Kim, J. H.; Kim, T. H.; Chung, Y. H.; Kim, S. B.; Kim, Y. M.; Kim, H. W., et al. In vitro Antibacterial Activity and Synergistic Antibiotic Effects of Phlorotannins Isolated from Eisenia Bicyclis Against Methicillin-Resistant Staphylococcus Aureus. Phytother. Res. 2013, 27(8), 1260. DOI: 10.1002/ptr.4851.
   PubMed Web of Science ®Google Scholar
• Lee, J.-H.; Eom, S.-H.; Lee, E.-H.; Jung, Y.-J.; Kim, H.-J.; Jo, M.-R.; Son, K.-T.; Lee, H.-J.; Kim, J. H.; Lee, M.-S. In vitro Antibacterial and Synergistic Effect of Phlorotannins Isolated from Edible Brown Seaweed Eisenia Bicyclis Against Acne-Related Bacteria. Algae 2014, 29(1), 47.
   Web of Science ®Google Scholar
• Oh, K.-B.; Lee, J. H.; Chung, S.-C.; Shin, J.; Shin, H. J.; Kim, H.-K.; Lee, H.-S.-J.-B., and Letters, M. C. Antimicrobial Activities of the Bromophenols from the Red Alga Odonthalia Corymbifera and Some Synthetic Derivatives. Bioorganic & Medicinal Chemistry Letters. 2008, 18(1), 104.
   PubMed Web of Science ®Google Scholar
• Gunaseelan, S.; Arunkumar, M.; Aravind, M. K.; Gayathri, S.; Rajkeerthana, S.; Mohankumar, V.; Ashokkumar, B., and Varalakshmi, P. Probing Marine Brown Macroalgal Phlorotannins as Antiviral Candidate Against SARS-CoV-2: Molecular Docking and Dynamics Simulation Approach. Molecular Diversity. 2022, 1.
   PubMed Web of Science ®Google Scholar
• Kumar, A.; Singh, R. P.; Kumar, I.; Yadav, P.; Singh, S. K.; Kaushalendra; Singh, P. K.; Gupta, R. K.; Singh, S. M.; Kesawat, M. S., et al. Algal Metabolites Can Be an Immune Booster Against COVID-19 Pandemic. Antioxidants 2022, 11(3), 452.
   Web of Science ®Google Scholar
• Ahn, M.-J.; Yoon, K.-D.; Min, S.-Y.; Lee, J. S.; Kim, J. H.; Kim, T. G.; Kim, S. H.; Kim, N.-G.; Huh, H.; Kim, J. Inhibition of HIV-1 Reverse Transcriptase and Protease by Phlorotannins from the Brown Alga Ecklonia Cava. Biol. Pharm. Bull. 2004, 27(4), 544. DOI: 10.1248/bpb.27.544.
   PubMed Web of Science ®Google Scholar
• Arioli, T.; Mattner, S. W.; Winberg, P. C. Applications of Seaweed Extracts in Australian Agriculture: Past, Present and Future. J. Appl. Phycol. 2015, 27(5), 2007. DOI: 10.1007/s10811-015-0574-9.
   PubMed Web of Science ®Google Scholar
• Nabti, E. Biotechnological Applications of Seaweeds; Nova Science Publishers: Hauppauge, New York, 2017.
   Google Scholar
• Verkleij, F. Seaweed Extracts in Agriculture and Horticulture: A Review. Biol. Agric. Hortic. 1992, 8(4), 309.
   Web of Science ®Google Scholar
• Crouch, I.; Beckett, R.; Van Staden, J. Effect of Seaweed Concentrate on the Growth and Mineral Nutrition of Nutrient-Stressed Lettuce. J. Appl. Phycol. 1990, 2(3), 269.
   Google Scholar
• Lola-Luz, T.; Hennequart, F.; Gaffney, M. Effect on Yield, Total Phenolic, Total Flavonoid and Total Isothiocyanate Content of Two Broccoli Cultivars (Brassica Oleraceae Var Italica) Following the Application of a Commercial Brown Seaweed Extract (Ascophyllum Nodosum). Agric. Food Sci. 2014, 23(1), 28.
   Web of Science ®Google Scholar
• Carvalho, M.; Castro, P. D. C.; Novembre, A., and Chamma, H. Seaweed Extract Improves the Vigor and Provides the Rapid Emergence of Dry Bean Seeds. American-Eurasian J. Agric. & Environ. Sci.,. 2013, 13(8), 1104.
   Google Scholar
• Aziz, N. G. A.; Mahgoub, M., and Siam, H. Growth, Flowering and Chemical Constituents Performance of Amaranthus Tricolor Plants as Influenced by Seaweed (Ascophyllum Nodosum) Extract Application Under Salt Stress Conditions. Journal of Applied Sciences Research. 2011, 7, 1472.
   Google Scholar
• Machado, L. P.; Matsumoto, S. T.; Jamal, C. M.; da Silva, M. B.; Centeno Dda, C.; Colepicolo Neto, P.; de Carvalho, L. R.; Yokoya, N. S. Chemical Analysis and Toxicity of Seaweed Extracts with Inhibitory Activity Against Tropical Fruit Anthracnose Fungi. J. Sci. Food Agric. 2014, 94(9), 1739. DOI: 10.1002/jsfa.6483.
   PubMed Web of Science ®Google Scholar
• Petropoulos, S. A.; Sami, R.; Benajiba, N.; Zewail, R. M. Y., and Mohamed, M. H. M. The Response of Globe Artichoke Plants to Potassium Fertilization Combined with the Foliar Spraying of Seaweed Extract. Agronomy. 2022, 12(2), 490.
   Google Scholar
• Morais, T.; Inácio, A.; Coutinho, T.; Ministro, M.; Cotas, J.; Pereira, L., and Bahcevandziev, K. Seaweed Potential in the Animal Feed: A Review. Journal of Marine Science and Engineering. 2020, 8(8), 559.
   Web of Science ®Google Scholar
• Holdt, S. L., and Kraan, S. Bioactive Compounds in Seaweed: Functional Food Applications and Legislation. Journal of Applied Phycology. 2011, 23(3), 543.
   Web of Science ®Google Scholar
• Bikker, P.; van Krimpen, M. M.; van Wikselaar, P.; Houweling-Tan, B.; Scaccia, N.; van Hal, J. W.; Huijgen, W. J. J.; Cone, J. W.; López-Contreras, A. M. Biorefinery of the Green Seaweed Ulva Lactuca to Produce Animal Feed, Chemicals and Biofuels. J. Appl. Phycol. 2016, 28(6), 3511. DOI: 10.1007/s10811-016-0842-3.
   PubMed Web of Science ®Google Scholar
• Singh, B. K.; Chopra, R. C.; Rai, S. N.; Verma, M. P., and Mohanta, R. K. Nutritional Evaluation of Seaweed on Nutrient Digestibility, Nitrogen Balance, Milk Production and Composition in Sahiwal Cows. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. 2017, 87(2), 437.
   Google Scholar
• Caroprese, M.; Ciliberti, M. G.; Marino, R.; Santillo, A.; Sevi, A.; Albenzio, M. Polyunsaturated Fatty Acid Supplementation: Effects of Seaweed Ascophyllum Nodosum and Flaxseed on Milk Production and Fatty Acid Profile of Lactating Ewes During Summer. J. Dairy Res. 2016, 83(3), 289. DOI: 10.1017/S0022029916000431.
   PubMed Web of Science ®Google Scholar
• Atiwesh, G.; Mikhael, A.; Parrish, C. C.; Banoub, J.; Le, T.-A.-T. Environmental Impact of Bioplastic Use: A Review. Heliyon. 2021, 7(9), e07918. DOI: 10.1016/j.heliyon.2021.e07918.
   PubMed Web of Science ®Google Scholar
• Muizniece-Brasava, S.; Dukalska, L., and Kantike, I., Consumer’s Knowledge and Attitude to Traditional and Environmentally Friendly Food Packaging Materials in Market of Latvia. The 6th Baltic Conference on Food Science and Technology “FoodBalt-2011, Jelgava, Latvia, 2011; pp 5.
   Google Scholar
• Jayakody, M. M.; Vanniarachchy, M. P. G., and Wijesekara, I. Seaweed Derived Alginate, Agar, and Carrageenan Based Edible Coatings and Films for the Food Industry: A Review. Journal of Food Measurement and Characterization. 2022, 16, 1.
   Web of Science ®Google Scholar
• Abdullah, N. A.; Mohamad, Z.; Khan, Z. I.; Jusoh, M.; Zakaria, Z. Y., and Ngadi, N. Alginate Based Sustainable Films and Composites for Packaging: A Review. Chemical Engineering Transactions. 2021, 83, 271–276.
   Google Scholar
• Phan, T. D.; Debeaufort, F.; Luu, D.; Voilley, A. Functional Properties of Edible Agar-Based and Starch-Based Films for Food Quality Preservation. J. Agric. Food Chem. 2005, 53(4), 973. DOI: 10.1021/jf040309s.
   PubMed Web of Science ®Google Scholar
• Han, J. H. 2014. Edible Films and Coatings: A Review. In Innovations in Food Packaging. H. Han, Jung;London NW1 7BY, UK: Academic Press, pp 213.
   Google Scholar
• Huq, T.; Salmieri, S.; Khan, A.; Khan, R. A.; Le Tien, C.; Riedl, B.; Fraschini, C.; Bouchard, J.; Uribe-Calderon, J.; Kamal, M. R., et al. Nanocrystalline Cellulose (NCC) Reinforced Alginate Based Biodegradable Nanocomposite Film. Carbohydr. Polym. 2012, 90(4), 1757. DOI: 10.1016/j.carbpol.2012.07.065.
   PubMed Web of Science ®Google Scholar
• Kanmani, P.; Rhim, J. W. Development and Characterization of Carrageenan/grapefruit Seed Extract Composite Films for Active Packaging. Int. J. Biol. Macromol. 2014, 68, 258. DOI: 10.1016/j.ijbiomac.2014.05.011.
   PubMed Web of Science ®Google Scholar
• Zhao, J.; Jiang, H.; Huang, Q.; Xu, J.; Duan, M.; Yu, S.; Zhi, Z.; Pang, J.; Wu, C. Carboxymethyl Chitosan Incorporated with Gliadin/phlorotannin Nanoparticles Enables the Formation of New Active Packaging Films. Int. J. Biol. Macromol. 2022, 203, 40. DOI: 10.1016/j.ijbiomac.2022.01.128.
   PubMed Web of Science ®Google Scholar
• Khalil, H. A.; Saurabh, C. K.; Tye, Y.; Lai, T.; Easa, A.; Rosamah, E.; Fazita, M.; Syakir, M.; Adnan, A., and Fizree, H. J. R., et al. Seaweed Based Sustainable Films and Composites for Food and Pharmaceutical Applications: A Review. Renewable and Sustainable Energy Reviews. 2017, 77, 353.
   Web of Science ®Google Scholar
• Grenha, A.; Gomes, M. E.; Rodrigues, M.; Santo, V. E.; Mano, J. F.; Neves, N. M.; Reis, R. L. Development of New Chitosan/carrageenan Nanoparticles for Drug Delivery Applications. J. Biomed. Mater. Res. A. 2010, 92(4), 1265.
   PubMed Web of Science ®Google Scholar
• Kevadiya, B. D.; Joshi, G. V.; Patel, H. A.; Ingole, P. G.; Mody, H. M., and Bajaj, H. C. Montmorillonite-Alginate Nanocomposites as a Drug Delivery System: Intercalation and in vitro Release of Vitamin B1 and Vitamin B6. Journal of Biomaterial applications. 2010, 25(2), 161.
   PubMed Web of Science ®Google Scholar
• Varghese, J. S.; Chellappa, N., and Fathima, N. N. Gelatin–carrageenan Hydrogels: Role of Pore Size Distribution on Drug Delivery Process. Colloids and Surfaces B: Biointerfaces. 2014, 113, 346.
   PubMed Web of Science ®Google Scholar
• Alves, A.; Pinho, E. D.; Neves, N. M.; Sousa, R. A., and Reis, R. L. Processing Ulvan into 2D Structures: Cross-Linked Ulvan Membranes as New Biomaterials for Drug Delivery Applications. International Journal of Pharmaceutics. 2012, 426(1–2), 76.
   PubMed Web of Science ®Google Scholar
• Bilal, M.; Iqbal, H. M. N. Marine Seaweed Polysaccharides-Based Engineered Cues for the Modern Biomedical Sector. Mar. Drugs. 2019, 18(1), 7. DOI: 10.3390/md18010007.
   PubMed Web of Science ®Google Scholar
• Madub, K.; Goonoo, N.; Gimié, F.; Ait Arsa, I.; Schönherr, H.; Bhaw-Luximon, A. Green Seaweeds Ulvan-Cellulose Scaffolds Enhance in vitro Cell Growth and in vivo Angiogenesis for Skin Tissue Engineering. Carbohydr. Polym. 2021, 251, 117025. DOI: 10.1016/j.carbpol.2020.117025.
   PubMed Web of Science ®Google Scholar
• Tan, S. P.; McLoughlin, P.; O’Sullivan, L.; Prieto, M. L.; Gardiner, G. E.; Lawlor, P. G.; Hughes, H. Development of a Novel Antimicrobial Seaweed Extract-Based Hydrogel Wound Dressing. Int. J. Pharmaceutics. 2013, 456(1), 10. DOI: 10.1016/j.ijpharm.2013.08.018.
   PubMed Web of Science ®Google Scholar
• Couteau, C., and Coiffard, L. Seaweed Application in Cosmetics. In Seaweed in Health and Disease Prevention. Fleurence, Joel; London EC2Y 5AS, UK: Elsevier, 2016; pp 423.
   Google Scholar
• Jesumani, V.; Du, H.; Aslam, M.; Pei, P.; Huang, N. Potential Use of Seaweed Bioactive Compounds in Skincare—a Review. 2019, 17(12), 688.
   Google Scholar
• Numata, T.; Kobayashi, Y.; Ito, T.; Harada, K.; Tsuboi, R., and Okubo, Y. Two Cases of Allergic Contact Dermatitis Due to Skin-Whitening Cosmetics. Allergology international. 2015, 64(2), 194.
   PubMed Web of Science ®Google Scholar
• Shibata, T.; Fujimoto, K.; Nagayama, K.; Yamaguchi, K., and Nakamura, T. Inhibitory Activity of Brown Algal Phlorotannins Against Hyaluronidase. Int. J. Food Sci. Technol. 2002, 37(6), 703.
   Web of Science ®Google Scholar
• Horvitz, S.; Chanaguano, D.; Arozarena, I. J. S. H. Andean Blackberries (Rubus Glaucus Benth) Quality as Affected by Harvest Maturity and Storage Conditions. Sci. Hortic. 2017, 226, 293.
   Web of Science ®Google Scholar
• Hegedus, F.; Mathew, L. M.; Schwartz, R. A. Radiation Dermatitis: An Overview. Int. J. Dermatol. 2017, 56(9), 909. DOI: 10.1111/ijd.13371.
   PubMed Web of Science ®Google Scholar
• Yang, K.; Kim, S. Y.; Park, J. H.; Ahn, W. G.; Jung, S. H.; Oh, D.; Park, H. C.; Choi, C. Topical Application of Phlorotannins from Brown Seaweed Mitigates Radiation Dermatitis in a Mouse Model. Mar. Drugs. 2020, 18, 8. DOI: 10.3390/md18080377.
   Web of Science ®Google Scholar
• Pandey, A.; Chauhan, O., and Semwal, A. Seaweeds—a Potential Source for Functional Foods. Defence Life Science Journal. 2020, 5 (4) , 315.
   Google Scholar
• Kasimala, M. B.; Mebrahtu, L.; Magoha, P. P.; Asgedom, G. A Review on Biochemical Composition and Nutritional Aspects of Seaweeds. CJST 2015, 3(1), 789.
   Google Scholar
• Kato, K.; Hayashi, M.; Umene, S., and Masunaga, H. A Novel Method for Producing Softened Edible Seaweed Kombu. LWT - Food Science and Technology. 2016, 65, 618.
   Web of Science ®Google Scholar
• Banu, A. T.; Mageswari, S. U. Nutritional Status and Effect of Seaweed Chocolate on Anemic Adolescent Girls. Food Sci. Hum. Wellness 2015, 4(1), 28.
   Google Scholar
• Cox, S.; Abu‐ghannam, N. Enhancement of the Phytochemical and Fibre Content of Beef Patties with H Imanthalia Elongata Seaweed. Int. J Food Sci. Technol. 2013, 48(11), 2239.
   Web of Science ®Google Scholar
• Kumoro, A.; Johnny, D., and Alfilovita, D. Incorporation of Microalgae and Seaweed in Instant Fried Wheat Noodles Manufacturing: Nutrition and Culinary Properties Study. International Food Research Journal. 2016, 23(2), 715–722.
   Web of Science ®Google Scholar
• Kaneko, J. J. Chapter 3 - Carbohydrate Metabolism and Its Diseases. In Clinical Biochemistry of Domestic Animals, 5th ed.; Kaneko, J. J., Harvey, J.W., and Bruss, M.L., Eds.; Academic Press: San Diego, 1997; pp 45.
   Google Scholar
• Hoffman, J. R., and Falvo, M. J. Protein–which is Best? Journal of sports science & medicine. 2004, 3(3), 118.
   PubMed Web of Science ®Google Scholar
• Gamero-Vega, G.; Palacios-Palacios, M., and Quitral, V. Nutritional Composition and Bioactive Compounds of Red Seaweed: A Mini-Review. Journal of Food and Nutrition Research. 2020, 8, 431.
   Google Scholar
• Santoso, J.; Gunji, S.; Yoshie-Stark, Y., and Suzuki, T. Mineral Contents of Indonesian Seaweeds and Mineral Solubility Affected by Basic Cooking. Food Science and Technology Research. 2006, 12(1), 59.
   Web of Science ®Google Scholar
• Tabarsa, M.; Rezaei, M.; Ramezanpour, Z.; Robert Waaland, J., and Rabiei, R. Fatty Acids, Amino Acids, Mineral Contents, and Proximate Composition of Some Brown Seaweeds. Journal of Phycology. 2012, 48(2), 285.
   PubMed Web of Science ®Google Scholar
• Olsson, J.; Toth, G. B.; Albers, E. Biochemical Composition of Red, Green and Brown Seaweeds on the Swedish West Coast. J. Appl. Phycol. 2020, 32(5), 3305. DOI: 10.1007/s10811-020-02145-w.
   Web of Science ®Google Scholar
• Guyton, A. C., and Hall, J. E. Textbook of Medical Physiology; Saunders Philadelphia: Elsevier, 1986; Vol. 548.
   Google Scholar
• Epstein, M., and World, R. Alcohol’s Impact on Kidney Function. Alcohol Health and Researh World. 1997, 21(1), 84.
   PubMedGoogle Scholar
• Laires, M. J.; Monteiro, C. P.; Bicho, M. Role of Cellular Magnesium in Health and Human Disease. Front. Biosci. 2004, 9(262), 262. DOI: 10.2741/1223.
   PubMedGoogle Scholar
• Lieu, P. T.; Heiskala, M.; Peterson, P. A.; Yang, Y. The Roles of Iron in Health and Disease. Mol. Aspects Med. 2001, 22(1–2), 1. DOI: 10.1016/S0098-2997(00)00006-6.
   PubMedGoogle Scholar
• Nielsen, C. W.; Rustad, T., and Holdt, S. L. Vitamin C from Seaweed: A Review Assessing Seaweed as Contributor to Daily Intake. Foods. 2021, 10(1), 198.
   PubMed Web of Science ®Google Scholar
• Praiboon, J.; Palakas, S.; Noiraksa, T.; Miyashita, K. Seasonal Variation in Nutritional Composition and Anti-Proliferative Activity of Brown Seaweed, Sargassum Oligocystum. J. Appl. Phycol. 2018, 30(1), 101. DOI: 10.1007/s10811-017-1248-6.
   Web of Science ®Google Scholar
• Semba, R. D. The Role of Vitamin a and Related Retinoids in Immune Function. Nutr. Rev. 1998, 56(1 Pt 2), S38. DOI: 10.1111/j.1753-4887.1998.tb01643.x.
   PubMed Web of Science ®Google Scholar
• Jacob, R. A.; Sotoudeh, G. Vitamin C Function and Status in Chronic Disease. Nutr Clin Care. 2002, 5(2), 66. DOI: 10.1046/j.1523-5408.2002.00005.x.
   PubMedGoogle Scholar
• Brigelius‐flohé, R., and Traber, M. G. Vitamin E: Function and Metabolism. The Federation of American Societies for Experimental Biology Journal. 1999, 13(10), 1145.
   PubMed Web of Science ®Google Scholar
• Vimaladevi, S.; Mahesh, A.; Dhayanithi, B. N.; Karthikeyan, N. Mosquito Larvicidal Efficacy of Phenolic Acids of Seaweed Chaetomorpha Antennina (Bory) Kuetz. Against Aedes Aegypti. Biologia. 2012, 67(1), 212. DOI: 10.2478/s11756-011-0152-9.
   Web of Science ®Google Scholar
• Elsayed, K. N.; Radwan, M. M.; Hassan, S. H.; Abdelhameed, M. S.; Ibraheem, I. B., and Ross, S. A. Phytochemical and Biological Studies on Some Egyptian Seaweeds. Natural Product Communication. 2012, 7(9), 1934578X1200700927.
   Web of Science ®Google Scholar
• Xie, X.; Chen, C., and Fu, X. Screening α-Glucosidase Inhibitors from Four Edible Brown Seaweed Extracts by Ultra-Filtration and Molecular Docking. LWT. 2021, 138, 110654.
   Web of Science ®Google Scholar
• Choudhary, B.; Chauhan, O.; Mishra, A. J. F. I. M. S. Edible Seaweeds: A Potential Novel Source of Bioactive Metabolites and Nutraceuticals with Human Health Benefits. Front. Mar. Sci. 2021, 8. DOI: 10.3389/fmars.2021.740054.
   Web of Science ®Google Scholar
• Ganesan, A. R.; Tiwari, U.; Rajauria, G. Seaweed Nutraceuticals and Their Therapeutic Role in Disease Prevention. Food Sci. Hum. Wellness. 2019, 8(3), 252. DOI: 10.1016/j.fshw.2019.08.001.
   Google Scholar
• Kim, K. Y.; Nguyen, T. H.; Kurihara, H.; Kim, S. M. Alpha-Glucosidase Inhibitory Activity of Bromophenol Purified from the Red Alga Polyopes Lancifolia. J. Food Sci. 2010, 75(5), H145.
   PubMed Web of Science ®Google Scholar
• Kurihara, H.; Mitani, T.; Kawabata, J., and Takahashi, K. Inhibitory Potencies of Bromophenols from Rhodomelaceae Algae Against α-Glucosidase Activity. Fisheries Science. 1999, 65(2), 300.
   Web of Science ®Google Scholar
• Kurihara, H.; Yachiyama, K. Decreasing Mechanism of Lipoxygenase-Mediated Peroxides by Seaweed Constituents. 2017.
   Google Scholar
• Blamo, P. A., Jr; Liu, X.; Tran, T. V. A., and M, S. Kim, β-Glucuronidase Inhibitory Activity of Bromophenol Isolated from Red Alga Grateloupia Lancifolia. Agriculture and Food. 2021, 6(2), 551.
   Google Scholar
• Shi, D.; Xu, F.; He, J.; Li, J.; Fan, X., and Han, L. Inhibition of Bromophenols Against PTP1B and Anti-Hyperglycemic Effect of Rhodomela Confervoides Extract in Diabetic Rats. Chinese Science Bulletin. 2008, 53(16), 2476.
   Google Scholar
• Xue, M.; Ge, Y.; Zhang, J.; Wang, Q.; Hou, L.; Liu, Y.; Sun, L.; Li, Q.; Tan, M. Anticancer Properties and Mechanisms of Fucoidan on Mouse Breast Cancer in vitro and in vivo. PLoS One. 2012, 7(8), e43483. DOI: 10.1371/journal.pone.0043483.
   PubMed Web of Science ®Google Scholar
• Isaza Martínez, J. H.; Torres Castañeda, H. G. Preparation and Chromatographic Analysis of Phlorotannins. J. Chromatogr. Sci. 2013, 51(8), 825. DOI: 10.1093/chromsci/bmt045.
   PubMed Web of Science ®Google Scholar
• Kellogg, J.; Grace, M. H., and Lila, M. A. Phlorotannins from Alaskan Seaweed Inhibit Carbolytic Enzyme Activity. Marine Drugs. 2014, 12(10), 5277.
   PubMed Web of Science ®Google Scholar
• Wang, Y.; Xu, Z.; Bach, S., and McAllister, T. Sensitivity of Escherichia Coli to Seaweed (Ascophyllum Nodosum) Phlorotannins and Terrestrial Tannins. Asian-Australasian Journal of Animal Sciences. 2009, 22(2), 238.
   Web of Science ®Google Scholar
• Zhang, R.; Yuen, A. K. L.; Magnusson, M.; Wright, J. T.; de Nys, R.; Masters, A. F.; Maschmeyer, T. A Comparative Assessment of the Activity and Structure of Phlorotannins from the Brown Seaweed Carpophyllum Flexuosum. Algal Res. 2018, 29, 130. DOI: 10.1016/j.algal.2017.11.027.
   Google Scholar
• Ahn, G.-N.; Kim, K.-N.; Cha, S.-H.; Song, C.-B.; Lee, J.; Heo, M.-S.; Yeo, I.-K.; Lee, N.-H.; Jee, Y.-H.; Kim, J.-S. Antioxidant Activities of Phlorotannins Purified from Ecklonia Cava on Free Radical Scavenging Using ESR and H 2 O 2-Mediated DNA Damage. Eur. Food Res. Technol. 2007, 226(1), 71.
   Web of Science ®Google Scholar
• Kannan, R. R. R.; Aderogba, M. A.; Ndhlala, A. R.; Stirk, W. A.; Van Staden, J. Acetylcholinesterase Inhibitory Activity of Phlorotannins Isolated from the Brown Alga, Ecklonia Maxima (Osbeck) Papenfuss. Food Res. Int. 2013, 54(1), 1250. DOI: 10.1016/j.foodres.2012.11.017.
   Web of Science ®Google Scholar
• Zhen, A. X.; Hyun, Y. J.; Piao, M. J.; Fernando, P. D. S. M.; Kang, K. A.; Ahn, M. J.; Yi, J. M.; Kang, H. K.; Koh, Y. S.; Lee, N. H., et al. Eckol Inhibits Particulate Matter 2.5-Induced Skin Keratinocyte Damage via MAPK Signaling Pathway. Mar. Drugs 2019, 17(8), 444.
   PubMed Web of Science ®Google Scholar
• Choi, J. G.; Kang, O. H.; Brice, O. O.; Lee, Y. S.; Chae, H. S.; Oh, Y. C.; Sohn, D. H.; Park, H.; Choi, H. G.; Kim, S. G., et al. Antibacterial Activity of Ecklonia Cava Against Methicillin-Resistant Staphylococcus Aureus and Salmonella Spp. Foodborne Pathog. Dis. 2010, 7(4), 435. DOI: 10.1089/fpd.2009.0434.
   PubMed Web of Science ®Google Scholar
• Lee, M.-S.; Shin, T.; Utsuki, T.; Choi, J.-S.; Byun, D.-S.; Kim, H.-R. Isolation and Identification of Phlorotannins from Ecklonia Stolonifera with Antioxidant and Hepatoprotective Properties in Tacrine-Treated HepG2 Cells. J. Agric. Food Chem. 2012, 60(21), 5340. DOI: 10.1021/jf300157w.
   PubMed Web of Science ®Google Scholar
• Okada, Y.; Ishimaru, A.; Suzuki, R.; Okuyama, T. A New Phloroglucinol Derivative from the Brown Alga Eisenia Bicyclis: Potential for the Effective Treatment of Diabetic Complications. J. Nat. Prod. 2004, 67(1), 103. DOI: 10.1021/np030323j.
   PubMed Web of Science ®Google Scholar
• Ahn, M.; Moon, C.; Yang, W.; Ko, E.-J.; Hyun, J. W.; Joo, H. G.; Jee, Y.; Lee, N. H.; Park, J. W.; Ko, R. K., et al. Diphlorethohydroxycarmalol, Isolated from the Brown Algae Ishige Okamurae, Protects Against Radiation-Induced Cell Damage in Mice. Food Chem. Toxicol. 2011, 49(4), 864. DOI: 10.1016/j.fct.2010.12.008.
   PubMed Web of Science ®Google Scholar
• Corona, G.; Coman, M. M.; Spencer, J. P., and Rowland, I. Digested and Fermented Seaweed Phlorotannins Reduce DNA Damage and Inhibit Growth of HT-29 Colon Cancer Cells. Proceedings of the Nutrition Society. 2014, 73(1), 1.
   PubMedGoogle Scholar
• Montero, L.; Sanchez-Camargo, A. P.; Garcia-Canas, V.; Tanniou, A.; Stiger-Pouvreau, V.; Russo, M.; Rastrelli, L.; Cifuentes, A.; Herrero, M.; Ibanez, E. Anti-Proliferative Activity and Chemical Characterization by Comprehensive Two-Dimensional Liquid Chromatography Coupled to Mass Spectrometry of Phlorotannins from the Brown Macroalga Sargassum Muticum Collected on North-Atlantic Coasts. J. Chromatogr. A. 2016, 1428, 115. DOI: 10.1016/j.chroma.2015.07.053.
   PubMed Web of Science ®Google Scholar
• Sugiura, Y.; Matsuda, K.; Okamoto, T.; Kakinuma, M.; Amano, H. Anti-Allergic Effects of the Brown Alga Eisenia Arborea on Brown Norway Rats. Fish. Sci. 2008, 74(1), 180.
   Web of Science ®Google Scholar
• Uchida, M.; Kurushima, H.; Ishihara, K.; Murata, Y.; Touhata, K.; Ishida, N.; Niwa, K.; Araki, T. Characterization of Fermented Seaweed Sauce Prepared from Nori (Pyropia Yezoensis). J. Biosci. Bioeng. 2017, 123(3), 327. DOI: 10.1016/j.jbiosc.2016.10.003.
   PubMed Web of Science ®Google Scholar
• Jenifer, A., and Kanjana, K. Effect of Seaweed Based Biscuit Supplementation on Anthropometric Profile of Malnourished Children Residing at Tuticorin. Journal of Science Technology. 2019, 4, 2349.
   Google Scholar
• López-López, I.; Bastida, S.; Ruiz-Capillas, C.; Bravo, L.; Larrea, M. T.; Sánchez-Muniz, F.; Cofrades, S.; Jiménez-Colmenero, F. Composition and Antioxidant Capacity of Low-Salt Meat Emulsion Model Systems Containing Edible Seaweeds. Meat Sci. 2009, 83(3), 492.
   PubMed Web of Science ®Google Scholar
• Sanjeewa, K. K. A.; Kim, E.-A.; Son, K.-T.; Jeon, Y.-J.-J.-J.-O.-P. Bioactive Properties and Potentials Cosmeceutical Applications of Phlorotannins Isolated from Brown Seaweeds: A Review. J. Photochem. Photobiol., B 2016, 162, 100.
   PubMed Web of Science ®Google Scholar
• Zhang, X.; Zhou, J.; Li, Z.; Qin, Y.; Yu, R.; Zhang, H.; Zheng, Y.; Zhu, J.; Zhang, D.; Fu, L. The Qualitative Electrochemical Determination of Multiple Components in Seaweed Fertilizer. Int. J. Electrochem. Sci. 2019, 14, 6283.
   Web of Science ®Google Scholar
• Tarafdar, J. Biostimulants for Sustainable Crop Production. 2022.
   Google Scholar
• Poddar, S., Seaweed Extract’s Use in Agriculture.
   Google Scholar
• Rengasamy, K. R.; Kulkarni, M. G.; Papenfus, H. B.; Van Staden, J. Quantification of Plant Growth Biostimulants, Phloroglucinol and Eckol, in Four Commercial Seaweed Liquid Fertilizers and Some By-Products. Algal Res. 2016, 20, 57.
   Google Scholar
• Spieler, R. Seaweed Compound’s Anti-HIV Efficacy Will Be Tested in Southern Africa. Lancet 2002, 359(9318), 1675.
   PubMed Web of Science ®Google Scholar
• Stokvis, E.; Rosing, H.; Lopez-Lazaro, L.; Rodriguez, I.; Jimeno, J. M.; Supko, J. G.; Schellens, J. H.; Beijnen, J. H. Quantitative Analysis of the Novel Depsipeptide Anticancer Drug Kahalalide F in Human Plasma by High-Performance Liquid Chromatography Under Basic Conditions Coupled to Electrospray Ionization Tandem Mass Spectrometry. J. Mass Spectrom. 2002, 37(9), 992. DOI: 10.1002/jms.362.
   PubMed Web of Science ®Google Scholar
• Teas, J.; Irhimeh, M. R.; Druker, S.; Hurley, T. G.; Hebert, J. R.; Savarese, T. M.; Kurzer, M. S. Serum IGF-1 Concentrations Change with Soy and Seaweed Supplements in Healthy Postmenopausal American Women. Nutr. Cancer. 2011, 63(5), 743. DOI: 10.1080/01635581.2011.579383.
   PubMed Web of Science ®Google Scholar
• Haskell-Ramsay, C. F.; Jackson, P. A.; Dodd, F. L.; Forster, J. S.; Bérubé, J.; Levinton, C.; Kennedy, D. O. Acute Post-Prandial Cognitive Effects of Brown Seaweed Extract in Humans. Nutrients 2018, 10(1), 85.
   PubMed Web of Science ®Google Scholar
• Santana, I.; Félix, M.; Guerrero, A.; Bengoechea, C. Processing and Characterization of Bioplastics from the Invasive Seaweed Rugulopteryx Okamurae. Polymers 2022, 14(2), 355.
   PubMed Web of Science ®Google Scholar
• Sudhakar, M. P.; Magesh Peter, D.; Dharani, G. Studies on the Development and Characterization of Bioplastic Film from the Red Seaweed (Kappaphycus Alvarezii). Environ. Sci. Pollut. Res. 2021, 28(26), 33899. DOI: 10.1007/s11356-020-10010-z.
   PubMed Web of Science ®Google Scholar
• Janarthanan, M.; Kumar, M. S. Novel Improvement of Bioactive Microencapsulated Textile Products Using Brown Seaweed for Healthcare Applications. Int. J. Clothing Sci. Technol. 2017, 29(2), 200–214. DOI: 10.1108/IJCST-03-2016-0023.
   Web of Science ®Google Scholar
• Ab Kadir, M.; Wan Ahmad, W.; Ahmad, M.; Misnon, M.; Ruznan, W.; Abdul Jabbar, H.; Ngalib, K., and Ismail, A., Utilization of Eco-Colourant from Green Seaweed on Textile Dyeing. Proceedings of the International Colloquium in Textile Engineering, Fashion, Apparel and Design 2014 (ICTEFAD 2014); Malayisa, Springer, 2014; pp 79.
   Google Scholar
• Yu, Z.; Robinson, S. M. C.; Xia, J.; Sun, H.; Hu, C. Growth, Bioaccumulation and Fodder Potentials of the Seaweed Sargassum Hemiphyllum Grown in Oyster and Fish Farms of South China. Aquaculture. 2016, 464, 459. DOI: 10.1016/j.aquaculture.2016.07.031.
   Web of Science ®Google Scholar
• Da Costa, A.; De Mesquita, L.; Tornovsky, J. Batch and Continuous Heavy Metals Biosorption by a Brown Seaweed from a Zinc-Producing Plant. Miner. Eng. 1996, 9(8), 811.
   Web of Science ®Google Scholar
• Davis, T.; Volesky, B.; Vieira, R. Sargassum Seaweed as Biosorbent for Heavy Metals. Water. Res. 2000, 34(17), 4270.
   Web of Science ®Google Scholar
• Khan, A. M.; Fatima, N.; Hussain, M. S.; Yasmeen, K. Biodiesel Production from Green Seaweed Ulva Fasciata Catalyzed by Novel Waste Catalysts from Pakistan Steel Industry. Chin. J. Chem. Eng. 2016, 24(8), 1080.
   Web of Science ®Google Scholar