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Original Articles

Executive Dysfunction in Pediatric Posterior Fossa Tumor Survivors: A Systematic Literature Review of Neurocognitive Deficits and Interventions

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Pages 153-175 | Received 11 Jul 2011, Accepted 06 Oct 2011, Published online: 17 Feb 2012

REFERENCES

  • Aarsen , F. K. , Paquier , P. F. , Arts , W. F. , Van Veelen , M. L. , Michiels , E. Lequin , M. 2009 . Cognitive deficits and predictors 3 years after diagnosis of a pilocytic astrocytoma in childhood . Journal of Clinical Oncology , 27 : 3526 – 3532 .
  • Aarsen , F. K. , Van Dongen , H. R. , Paquier , P. F. , Van Mourik , M. and Catsman-Berrevoets , C. E. 2004 . Long-term sequelae in children after cerebellar astrocytoma surgery . Neurology , 62 : 1311 – 1316 .
  • American Cancer Society. 2007. Cancer Facts and Figures 2007. Atlanta, GA: American Cancer Society http://www.cancer.org/downloads/STT/CAFF2007PWSecured.pdf (http://www.cancer.org/downloads/STT/CAFF2007PWSecured.pdf)
  • Anderson , J. R. 2004 . Cognitive psychology and its implications , New York , NY : Worth Publishers .
  • Anderson , N. E. 2005 . Late complications in childhood central nervous system tumour survivors . Current Opinion in Neurology , 16 : 677 – 683 .
  • Anderson , V. A. , Anderson , P. , Northam , E. , Jacobs , R. and Catroppa , C. 2001 . Development of executive functions through late childhood and adolescence in an Australian sample . Developmental Neuropsychology , 20 ( 1 ) : 385 – 406 .
  • Aukema , E. J. , Caan , M. W. A. , Oudhuis , N. , Majoiem , C. B. L. M. , Vos , F. M. , Reneman , L. … and Schouten-VanMeeteren , M. D. 2009 . White matter fractional anisotropy correlates with speed of processing and motor speed in young childhood cancer survivors . International Journal of Radiation Oncology Biology Physics , 74 : 837 – 843 .
  • Barnea-Goraly , N. , Menon , V. , Eckert , M. , Tamm , L. , Bammer , R. , Karchemskiy , A. … and Reiss , A. L. 2005 . White matter development during childhood and adolescence: A cross-sectional diffusion tensor imaging study . Cerebral Cortex , 15 ( 12 ) : 1848 – 1854 .
  • Baron , I. S. 2004 . Neuropsychological evaluation of the child , New York , NY : Oxford University Press .
  • Blakemore , S. and Choudhury , S. 2006 . Development of the adolescent brain: Implications for executive function and social cognition . Journal of Child Psychology and Psychiatry , 47 : 296 – 312 .
  • Briere , M. E. , Scott , J. G. , McNall-Knapp , R. Y. and Adams , R. L. 2008 . Cognitive outcome in pediatric brain tumor survivors: Delayed attention deficit at long-term follow-up . Pediatric Blood and Cancer , 50 : 337 – 340 .
  • Butler , R. W. , Copeland , D. R. , Fairclough , D. L. , Mulhern , R. K. , Katz , E. R. , Kazak , A. E. … and Sahler , O. J. Z. 2008 . A multicenter, randomized clinical trial of a cognitive remediation program for childhood survivors of a pediatric malignancy . Journal of Consulting and Clinical Psychology , 76 : 367 – 378 .
  • Casey , B. J. , Cohen , J. D. , Jezzard , P. , Turner , R. , Noll , D. C. , Trainor , R. J. … and Rapoport , J. L. 1995 . Activation of prefrontal cortex in children during a nonspatial working memory task with functional MRI . Neuroimage , 2 : 221 – 229 .
  • Casey , B. J. , Trainor , R. J. , Orendi , J. L. , Schubert , A. B. , Nystrom , L. E. , Giedd , J. N. … and Rapoport , J. L. 1997 . A developmental functional MRI study of prefrontal activation during performance of a go-no-go task . Journal of Cognitive Neuroscience , 9 : 835 – 847 .
  • CBTRUS. (2008). CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2004–2006. Source: Central Brain Tumor Registry of the United States, Hinsdale, IL. website www.cbtrus.org (http://www.cbtrus.org)
  • Committee on Children with Disabilities and Committee on Drugs: Mediation for children with attention disorders . 1996 . Pediatrics , 98 : 301 – 304 .
  • Conklin , H. M. , Khan , R. B. , Reddick , W. E. , Helton , S. , Brown , R. , Howard , S. C. … and Mulhern , R. K. 2007 . Acute neurocognitive response to methylphenidate among survivors of childhood cancer: A randomized, double-blind, cross-over trial . Journal of Pediatric Psychology , 32 : 1127 – 1139 .
  • Conklin , H. M. , Reddick , W. E. , Ashford , J. , Ogg , S. , Howard , S. C. , Morris , E. B. … and Khan , R. B. 2010 . Long-term efficacy of methylphenidate in enhancing attention regulation, social skills, and academic abilities of childhood cancer survivors . Journal of Clinical Oncology , 28 : 4465 – 4472 .
  • Crawford , J. R. , MacDonald , T. J. and Packer , R. J. 2007 . Medulloblastoma in childhood: New biological advances . Lancet Neurology , 6 : 1073 – 1085 .
  • De Smet , H. J. , Baillieux , H. , Wackenier , P. , De Praeter , M. , Engelborghs , S. , Phillipe , F. … and Marien , P. 2009 . Long-term cognitive deficits following posterior fossa tumor resection: A neuropsychological and functional neuroimaging follow-up study . Neuropsychology , 23 : 694 – 704 .
  • Diamond , A. 1988 . Abilities and neural mechanisms underlying AB performance . Child Development , 59 : 523 – 527 .
  • Ellenberg , L. , Liu , Q. , Gioia , G. , Yasui , Y. , Packer , R. J. , Mertens , A. … and Zeltzer , L. K. 2009 . Neurocognitive status in long-term survivors of childhood CNS malignancies: A report from the Childhood Cancer Survivor Study . Neuropsychology , 23 : 705 – 717 .
  • Fuster , J. M. 1989 . The prefrontal cortex: Anatomy, physiology, and neuropsychology of the frontal lobe , New York , NY : Raven Press .
  • Giedd , J. N. 2008 . The teen brain: Insights from neuroimaging . Journal of Adolescent Health , 42 : 335 – 343 .
  • Goldman-Rakic , P. S. 1987 . “ Circuitry of the prefrontal cortex and the regulation of behavior by representational memory ” . In Handbook of physiology: The nervous system (Vol. 5, pp. 373–417) , Edited by: Mountcastle , V. Bethesda, MD: American Physiological Society .
  • Gurney , J. G. , Kadan-Lottick , N. S. , Packer , R. J. , Neglia , J. P. , Sklar , C. A. , Punyko , J. A. … and Robison , L. L. 2003 . Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors . Cancer , 97 : 663 – 673 .
  • Hardy , K. K. , Willard , V. W. and Bonner , M. J. 2011 . Computerized cognitive training in survivors of childhood cancer: A pilot study . Journal of Pediatric Oncology Nursing , 28 : 27 – 33 .
  • Ito , H. , Kanno , I. , Takahashi , K. , Ibaraki , M. and Miura , S. 2003 . Regional distribution of human cerebral vascular mean transit time measured by positron emission tomography . NeuroImage , 19 : 1163 – 1169 .
  • Jain , N. , Krull , K. R. , Prouwers , P. , Chintagumpala , M. M. and Woo , S. Y. 2008 . Neuropsychological outcome following intensity-modulated radiation therapy for pediatric medulloblastoma . Pediatric Blood Cancer , 51 : 275 – 279 .
  • Kaatsch , P. 2010 . Epidemiology of childhood cancer . Cancer Treatment Reviews , 36 : 277 – 285 .
  • Levisohn , L. , Cronin-Golomb , A. and Schmahmann , J. D. 2000 . Neuropsychological consequences of cerebellar tumour resection in children . Brain , 123 : 1041 – 1050 .
  • Lezak , M. D. 2004 . Neuropsychological assessment , 3rd , New York , NY : Oxford University Press .
  • Luciana , M. , Conklin , H. M. , Cooper , C. J. and Yarger , R. S. 2005 . The development of nonverbal working memory and executive control processes in adolescents . Child Development , 76 : 697 – 712 .
  • Luna , B. , Thulborn , K. R. , Munoz , D. P. , Merriam , E. , Garver , K. E. , Minshew , N. J. … and Sweeney , J. A. 2001 . Maturation of widely distributed brain function subserves cognitive development . NeuroImage , 13 : 786 – 793 .
  • Luna , B. and Sweeney , J. A. 2004 . The emergence of collaborative brain function: fMRI studies of the development of response inhibition . Annals of New York Academy of Sciences , 1021 : 296 – 309 .
  • Mabbott , D. J. , Penkman , L. , Witol , A. , Strother , D. and Bouffet , E. 2008 . Core neurocognitive functions in children treated for posterior fossa tumors . Neuropsychology , 22 ( 2 ) : 159 – 168 .
  • Mabbott , D. J. , Snyder , J. J. , Penkman , L. and Witol , A. 2009 . The effects of treatment for posterior fossa brain tumors on selective attention . Journal of the International Neuropsychological Society , 15 : 205 – 216 .
  • Maddrey , A. M. , Bergeron , J. A. , Lombardo , E. R. , McDomald , N. K. , Mulne , A. F. , Barenberg , P. D. … and Bowers , D. C. 2005 . Neuropsychological performance and quality of life of 10 year survivors of childhood medulloblastoma . Journal of Neurooncology , 72 : 245 – 253 .
  • Marcovitch , S. and Zelazo , P. D. 2009 . A hierarchical competing systems model of the emergence and early development of executive function . Developmental Science , 12 : 1 – 18 .
  • McGivern , R. F. , Andersen , J. , Byrd , D. , Mutter , K. L. and Reilly , J. 2002 . Cognitive efficiency on a match to sample task decreases at the onset of puberty in children . Brain and Cognition , 50 : 73 – 89 .
  • Mennes , M. , Stiers , P. , Vandenbussche , E. , Vercruysse , G. , Uyttebroeck , A. , De Meyer , G. and Van Gool , S. W. 2005 . Attention and information processing in survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only . Pediatric Blood Cancer , 44 : 478 – 486 .
  • Mesulam , M.-M. 2000 . Principles of behavioral and cognitive neurology , New York , NY : Oxford University Press .
  • Mirsky , A. F. , Anthony , B. J. , Duncan , C. C. , Ahearn , M. B. and Kellam , S. G. 1991 . Analysis of the elements of attention: A neuropsychological approach . Neuropsychology Review , 2 : 109 – 144 .
  • Mulhern , R. K. , Khan , R. B. , Kaplan , S. , Helton , S. , Christensen , R. , Bonner , M. … and Reddick , W. E. 2004b . Short-term efficacy of methylphenidate: A randomized, double-blind, placebo-controlled trial among survivors of childhood cancer . Journal of Clinical Oncology , 22 : 4795 – 4803 .
  • Mulhern , R. K. , Palmer , S. L. , Reddick , W. E. , Glass , J. O. , Kun , L. E. , Taylor , J. … and Gajjar , A. 2001 . Risks of young age for selected neurocognitive deficits in medulloblastoma are associated with white matter loss . Journal of Clinical Oncology , 19 : 472 – 479 .
  • Mulhern , R. K. , White , H. A. , Glass , J. O. , Kun , L. E. , Leigh , L. , Thompson , S. J. … and Reddick , W. E. 2004a . Attentional functioning and white matter integrity among survivors of malignant brain tumors of childhood . Journal of the International Neuropsychological Society , 10 : 180 – 189 .
  • Muzamdar , D. and Ventureyra , E. C. G. 2010 . Treatment of posterior fossa tumors in children . Expert Review of Neurotherapeutics , 10 : 525 – 546 .
  • Palmer , S. L. 2008 . Neurodevelopmental impacts on children treated for medulloblastoma: A review and proposed conceptual model . Developmental Disabilities Research Reviews , 14 : 201 – 210 .
  • Pashler , H. 1988 . The psychology of attention , Cambridge , MA : MIT Press .
  • Patel , S. K. , Katz , E. R. , Richardson , R. , Rimmer , M. and Kilian , S. 2009 . Cognitive and problem solving training in children with cancer: A pilot project . Journal of Pediatric Hematology Oncology , 31 : 670 – 677 .
  • Qiu , D. , Kwong , D. L. W. , Chan , G. C. F. , Leung , L. H. T. and Khong , P.-L. 2007 . Diffusion tensor magnetic resonance imaging finding of discrepant fractional anisotropy between the frontal and parietal lobes after whole-brain irradiation in childhood medulloblastoma survivors: Reflection of regional white matter radiosensitivity? . International Journal of Radiation Oncology Biology Physics , 69 : 846 – 851 .
  • Reddick , W. E. , White , H. A. , Glass , J. O. , Wheeler , G. C. , Thompson , S. J. , Gajjar , A. … and Mulhern , R. K. 2003 . Developmental model relating white matter volume to neurocognitive deficits in pediatric brain tumor survivors . Cancer , 97 : 2512 – 2519 .
  • Reeves , C. B. , Palmer , S. L. , Reddick , W. E. , Merchant , T. E. , Buchanan , G. M. , Gajjar , A. … and Mulhern , R. K. 2006 . Attention and memory functioning among pediatric patients with medulloblastoma . Journal of Pediatric Psychology , 31 : 272 – 280 .
  • Reinhold , H. S. , Calvo , W. , Hopewell , J. W. and Van Den Breg , A. P. 1990 . Development of blood vessel-related radiation damage in the fimbria of the central nervous system . International Journal of Radiation Oncology Biology Physics , 18 : 37 – 42 .
  • Ribi , K. , Relly , C. , Landolt , M. A. , Alber , F. D. , Boltshauser , E. and Grotzer , M. A. 2005 . Outcome of medulloblastoma in children: Long-term complications and quality of life . Neuropediatrics , 36 : 357 – 365 .
  • Ris , M. D. , Beebe , D. W. , Armstrong , F. D. , Fontanesi , J. , Holmes , E. , Sanford , R. A. and Wisoff , J. H. 2008 . Cognitive and adaptive outcome in extracerebellar low-grade brain tumors in children: A report from the Children's Oncology Group . Journal of Clinical Oncology , 26 : 4765 – 4770 .
  • Riva , D. and Giorgi , C. 2000 . The cerebellum contributes to higher functions during development . Brain , 123 : 1051 – 1061 .
  • Ronning , C. , Sundet , K. , Due-Tonnessen , B. , Lundar , T. and Helseth , E. 2005 . Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumor in childhood . Pediatric Neurosurgery , 41 : 15 – 21 .
  • Schmahmann , J. D. and Sherman , J. C. 1998 . The cerebellar cognitive affective syndrome . Brain , 121 : 561 – 579 .
  • Scott , R. B. , Stoodley , C. J. , Anslow , P. , Paul , C. , Stein , J. F. , Sugden , E. M. and Mitchell , C. D. 2001 . Lateralized cognitive deficits in children following cerebellar lesions . Developmental Medicine & Child Neurology , 43 : 685 – 691 .
  • Sowell , E. R. , Thompson , P. M. , Holmes , C. J. , Batth , R. , Jernigan , T. L. and Toga , A. W. 1999 . Localizing age related changes in brain structure between childhood and adolescence using statistical parametric mapping . NeuroImage , 6 : 587 – 597 .
  • Spiegler , B. J. , Bouffet , E. , Greenberg , M. L. , Rutka , J. T. and Mabbott , D. J. 2004 . Change in neurocognitive functioning after treatment with cranial radiation in childhood . Journal of Clinical Oncology , 22 : 706 – 713 .
  • Steinlin , M. , Imfeld , S. , Zulauf , P. , Boltshauser , E. , Lovblad , K. O. , Luthy , A. R. … and Kaufmann , F. 2003 . Neuropsychological long-term sequelae after posterior fossa tumour resection during childhood . Brain , 126 : 1998 – 2008 .
  • Thomas , P. R. M. , Deutsch , M. , Kepner , J. L. , Boyett , J. M. , Krischer , J. , Aronin , P. … and Kun , L. E. 2000 . Low-stage medulloblastoma: Final analysis of trial comparing standard-dose with reduced-dose neuraxis irradiation . Journal of Clinical Oncology , 18 : 3004 – 3011 .
  • Thompson , S. J. , Leigh , L. , Christensen , R. , Xiong , X. , Kun , L. E. , Heideman , R. L. … and Mulhern , R. K. 2001 . Immediate neurocognitive effects of methylphenidate on learning-impaired survivors of childhood cancer . Journal of Clinical Oncology , 19 : 1802 – 1808 .
  • Turken , A. U. , Whitfield-Gabrieli , S. , Baummer , R. , Baldo , J. , Dronkers , N. F. and Gabrieli , J. D. E. 2008 . Cognitive processing speed and the structure of white matter pathways: Convergent evidence from normal variation and lesion studies . NeuroImage , 2 : 1032 – 1044 .
  • Ullen , F. 2009 . Is activity regulation of late myelination a plastic mechanism in the human nervous system? . Neuron Glia Biology , 5 : 29 – 34 .
  • Waber , D. P. , Pomeroy , S. L. , Chiverton , A. M. , Kieran , M. W. , Scott , R. M. , Goumnerova , L. C. … and Rivkin , M. J. 2006 . Everyday cognitive function after craniopharyngioma in childhood . Pediatric Neurology , 34 : 13 – 19 .
  • Woo , T.-U. , Pucak , M. L. , Kye , C. H. , Matus , C. V. and Lewis , D. A. 1997 . Peripubertal refinement of the intrinsic and associational circuitry in monkey prefrontal cortex . Neuroscience , 80 : 1149 – 1158 .
  • Zuzak , T. J. , Poretti , A. , Drexel , B. , Zehnder , D. , Boltshauser , E. and Grotzer , M. A. 2008 . Outcome of children with low-grade cerebellar astrocytoma: Long-term complications and quality of life . Child's Nervous System , 24 : 1447 – 1455 .

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