194
Views
97
CrossRef citations to date
0
Altmetric
(RG) Obstetrics and Gynaecology

Addition of testosterone to estrogen replacement therapy in oophorectomized women: effects on sexuality and well-being

, , &
Pages 357-365 | Published online: 03 Jul 2009

References

  • Zumoff B, Strain GW, Miller LK, et al. Twenty-four hour mean plasma testosterone concentra-tions decline with age in normal premenopausal women. J Gun Endocrinol Metab 1995;80: 1429–30
  • Lobo RA. Androgens in postmenopausal women: production, possible role, and replacement options. Obstet Gynecol Surv 2001;56:361–76
  • Davis S. Androgen replacement in women: a commentary. J Gun Endocrinol Metab 1999;84: 1886–91
  • Judd HL, Judd GE, Lucas EE, et al. Endocrine function of the postmenopausal ovary: concen-trations of androgens and estrogens in ovarianand peripheral vein blood. J Gun Endocrinol Metab 1974;39:1020–4
  • Sherwin BN, Gelfand MM, Brender W. Andro-gen enhances sexual motivation in females: a prospective crossover study of sex steroid admin-istration in surgical menopause. Psycbosom Med 1985;47:339–51
  • Davis SR, McCloud PI, Strauss BJG, et al. Testos-terone enhances estradiol's effects on postmeno-pausal bone density and sexuality. Maturitas 1995;21:227–36
  • Hickock LR, Toomey C, Speroff L. A comparison of esterified estrogens with and without methyltestosterone: effects on endometrialhistology and serum lipoproteins in post-menopausal women. Obstet Gynecol 1993;82: 919–24
  • Shifren JL, Braunstein GD, Simon JA, et al. Transdermal testosterone treatment in women with impaired sexual function after oophor-ectomy. N Engl J Med 2000;343:682–8
  • Coert A, Geelen J, de Visser J, et al. The pharma-cology and metabolism of testosterone undecanoate (TU), a new orally active androgen. Acta Endocrinol 1975;79:789–800
  • Flöter A, Carlström K, von Schoultz B, et al. Administration of testosterone undecanoate in postmenopausal women: effects on androgens, estradiol and gonadotrophins. Menopause 2000;7:251–6
  • McCoy N, Davidson J. A longitudinal study of the effects of menopause on sexuality. Maturitas 1985;7:203–10
  • Nathorst-Boos J, von Schoultz B, Carlström K. Elective ovarian removal and estrogen replace-ment therapy: effects on sexual life, psychological well-being and androgen status. J Psychosom Obstet Gynaecol 1993;14:283–93
  • Brody S, Carlström K, Lagrelius A, et al. Serum levels of 4-androstene-3,17-dione in menstruat-ing and postmenopausal women. Evaluation of a radioimmunoassay and correlation to bone mineral content and endometrial pathology. Acta Obstet Gynecol Scand 1983;62:531–4
  • Stege R, Eriksson A, Henriksson P, et al. Orchidectomy or estrogen treatment in prostatic cancer: effects on serum levels of adrenal andro-gens and related steroids. Int J Androl 1987;10: 581–7
  • Sodergard R, Bäckstrom T, Shanbag V, et al. Calculation of free and bound fractions of testosterone and estradio1-170 to plasma proteins at body temperature. J Steroid Biochem 1982; 18:801–4
  • Rosenberg MJ, King TD, Timmons CM. Estrogen—androgen for hormone replacement. A review. J Reprod Med 1997;42:394–404
  • Campbell S. Double-blind psychometric studies on the effects of natural estrogens on post-menopausal women. In Campbell S, ed. The Management of the Menopausal and Post-menopausal Years. Baltimore, MD: Baltimore University Park Press, 1976:149–58
  • Nathorst-Boös J, Wiklund I, Mattsson L-A, et al. Is sexual life influenced by transdermal estrogen therapy: a double-blind placebo-controlled study in postmenopausal women. Acta Obstet Gynecol Scand 1993;72:656–60
  • Studd JWW, Collins WP, Chakravarti S. Estradiol and testosterone implants in the treat-ment of psychosexual problems in postmeno-pausal women. Br J Obstet Gynaecol 1977;84: 314–15
  • Gower BA, Nyman L. Associations among oral estrogen use, free testosterone concen-tration, and lean body mass among postmeno-pausal women. J Clin Endocrinol Metab 2000; 85:4476–80
  • Flöter A, Nathorst-Botis J, Carlström K, et al. Androgen status and sexual life in perimeno-pausal women. Menopause 1997;4:95–100
  • Dennerstein L, Dudley E, Guthrie J, et al. Life satisfaction, symptoms and the menopausal transition. Medscape Women's Health 2000; 5 :E4
  • Wiklund I, Berg G, Hammar M, et al. Long-term effects of transdermal hormonal therapy on aspects of quality of life in postmenopausal women. Maturitas 1992;14:225–36
  • Sherwin BB, Gelfand MM. Differential symptom response to parenteral estrogen and/or androgen administration in the surgical menopause. Am J Obstet Gynecol 1985;151:153–60
  • Wiklund I. Methods of assessing the impact of climacteric complaints on quality of life. Maturitas 1998;29:41–50
  • Skarsgárd C, Berg GE, Ekblad S, et al. Effects of estrogen therapy on well-being in postmeno-pausal women without vasomotor complaints. Maturitas 2000;36:123–30
  • Wiklund IK. Hypertension. In Spilker B, ed. Quality of Life and Pharmacoeconomics in Clinical Trials, 2nd edn. Philadelphia, PA: Lippincott-Raven,1996:893— 902
  • Barett-Connor E, von Muhlen D, Laughlin GA, et al. Endogenous levels of dehydroepiandro-sterone sulfate, but no other sex hormones, are associated with depressed mood in women: the Rancho Bernardo Study. J Am Geriatr Soc 1999;47:685–91
  • Yaffe K, Ettinger B, Pressman A, et al. Neuro-psychiatric function and dehydroepiandro-sterone sulfate in elderly women: a prospective study. Biol Psychiatry 1998;43:694–700
  • Morales AJ, Nolan JJ, Nelson JC, et al. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab 1994;78:1360–7
  • Carlström K. Transformations of steroids by cell-free preparations of Penicillium lilacinum NRRL 895. IV. Enzyme catalyzed acyl transfer. Acta Chem Scand 1974;B28:23–8
  • Carlström K, Döberl A, Rannevik G. Peripheral androgen levels in danazol-treated premeno-pausal women. Fertil Steril 1983;39:499–504

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.