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Research Article

Alternative Splicing of Type II Procollagen Gene in the Dedifferentiation of Rat Epiphyseal Chondrocytes Serially Cultured in Monolayer

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Pages 56-62 | Published online: 06 Aug 2009

References

  • Brittberg, M., Lindahl, A., Nilsson, A., Ohlsson, C., Isaksson, O., and Peterson, L. (1994). Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N. Engl. J. Med. 331:889–895.
  • Archer, C.W., McDowell, J., Bayliss, M.T., Stephens, M.D., and Bentley, G. (1990). Phenotypic modulation in sub-populations of human articular chondrocytes in vitro. J. Cell. Sci. 97:361–371.
  • Chacko, S., Abbot, J., Holtzer, S., and Holtzer, H. (1969). The loss of phenotypic traits by differentiated cells: Behavior of the progeny of a single chondrocyte. J. Exp. Med. 130:417–442.
  • von der Mark, K., Gauss, V., von der Mark, H., and Muller, P. (1977). Relationship between cell shape and type of collagen synthesized as chon- drocytes lose their cartilage phenotype in culture. Nature 267:531–532.
  • Elima, K., and Vuorio, E. (1989). Expression of mRNAs for collagens and other matrix components in dedifferentiating and redifferentiating human chondrocytes in culture. FEBS Lett. 258:195–198.
  • Mayne, R., Vail, M.S., Mayne, P.M., and Miller, E.J. (1976). Changes in type of collagen synthesized as clones of chick chondrocytes grow and eventually lose division capacity. Proc. Natl. Acad. Sci., U.S.A. 73:1674–1678.
  • Horton, W., and Hassell, J.R. (1986). Independence of cell shape and loss of cartilage matrix production during retinoic acid treatment of cultured chondrocytes. Dev. Biol. 115:392–397.
  • Mallein-Gerin, F., Ruggiero, F., and Garrone, R. (1990). Proteoglycan core protein and type II collagen gene expression are not correlated with cell shape changes during low density chondrocyte cultures. Differentiation 43:204–211.
  • Shakibaei, M., Souza, P., and Merker, H.J. (1997). Integrin expression and collagen type II implicated in maintenance of chondrocyte shape in monolayer culture: An immunomorphologic study. Cell Biol. Int. 21:115–125.
  • Kosher, R.A., and Solursh, M. (1989). Widespread distribution of type II collagen during limb cartilage differentiation. Dev. Bio. 108:164–172.
  • Wood, A., Ashhurst, D.E., Corbett, A., and Thorogood, P. (1991). The tran- sient expression of type II collagen at tissue interfaces during craniofacial development. Development 111:955–968.
  • Ryan, M.C., and Sandell, L.J. (1990). Differential expression of a cysteine- rich domain in the amino-terminal propeptide of type II (cartilage) procol- lagen by alternative splicing of mRNA. J. Biol. Chem. 265:10334–10339.
  • Ryan, M.C., Sieraski, M., and Sandell, L.J. (1990). The human type II procollagen gene: Identification of an additional protein-coding domain and location of potential regulatory sequences in the promoter and first intron. Genomics 8:41–48.
  • Ng, L.J., Tam, P.P., and Cheah, K.S. (1993). Preferential expression of alternatively spliced mRNAs encoding type II procollagen with a cystein- rich amino-propeptide in differentiating cartilage and nonchondrogenic tissues during early mouse development. Dev. Biol. 159:403–417.
  • Sandell, L.J., Morris, N., Robbins, J.R., and Goldring, M.R. (1991). Alter- natively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: Differential expression of the amino- propeptide. J. Cell. Biol. 114:1307–1319.
  • Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA iso- lation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156–159.
  • Kim, H.J., Urabe, K., Sarkar, G., Bronk, J.T., and Bolander, M.E. (1995). Evidence of the regulation of type IIA procollagen messenger RNA during fracture repair. Trans. Orthop. Res. Soc. 20: 591.
  • Wilcox, J.N. (1993). Fundamental principles of in situ hybridization. J. Histochem. Cytochem. 41:1725–1733.
  • Martin, I., Vunjak-Novakovic, G., Yang, J., Langer, R., and Freed, L.E. (1999). Mammalian chondrocytes expanded in the presence of fibroblast growth factor 2 maintain the ability to differentiate and re- generate three-dimensional cartilaginous tissue. Exp. Cell. Res. 253:681–688.
  • Sandell, L.J., Nalin, A.M., and Reife, R.A. (1994). Alternative splice form of type II procollagen mRNA (IIA) is predominant in skeletal precursors and non-cartilaginous tissues during early mouse development. Dev. Dyn. 199:129–140.
  • Lui, V.C.H., Ng, L.J., Nicholls, J., Tam, P.P.L., and Cheah, K.S.E. (1995). Tissue-specific and differential expression of alternatively spliced al- pha (II) collagen mRNAs in early human embryos. Dev. Dyn. 203:198–211.
  • Oganesian, A., Zhu, Yong., and Sandell, L.J. (1997). Type IIA procollagen amino propeptide is localized in human embryonic tissues. J. Histochem. Cytochem. 45:1469–1480.

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