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Research Article

Iron prophylaxis during pregnancy - How much iron is needed? A randomized dose- response study of 20-80 mg ferrous iron daily in pregnant women

Pages 238-247 | Published online: 03 Aug 2009

References

  • Hallberg L. Iron balance in pregnancy. In: Berger H, ed. Vitamins and Minerals in Pregnancy and Lactation. Nestle Nutrition Workshop Series. 1988; 16: 115–27.
  • Milman N, Bergholt T, Byg K-E, Eriksen L, Graudal N. Iron status and iron balance during pregnancy. A critical reappraisal of iron supplementation. Acta Obstet Gynecol Scand 1999; 78: 749–57.
  • Milman N, Agger OA, Nielsen OJ. Iron supplementation during pregnancy. Effect on iron status markers, serum erythropoietin and human placental lactogen. A placebo controlled study in 207 Danish women. Dan Med Bull 1991; 38: 471–6.
  • Milman N, Byg K-E, Graudal N, Agger AO. Reference values for hemoglobin and erythrocyte indices during normal pregnancy in 206 women with and without iron supplementation. Acta Obstet Gynecol Scand 2000; 78: 89–98.
  • US Preventive Services Task Force. Routine iron supplementation during pregnancy. Policy statement. Review article. JAMA 1993; 270: 2846–54.
  • Report of a Joint FAO/WHO Expert Consultation. Requirements of vitamin A, iron, folate and vitamin B12. FAO Food NutrPap 1988; 23: 33–50.
  • Department of Health. Report on Health and Social Subjects. Dietary reference values for food energy and nutrients for the United Kingdom. HSMO 1991; report no. 41: 161–6.
  • Commision of the European Communities. Nutrient and energy intakes for the European Community. Reports of the Scientific Committee for Food. Directorate-General Industry 1993; 31st series: 180–1.
  • Nordic Council of Ministers. Nordic Nutrition Recommendations. Scand J Nutr 1996; 40: 161–5.
  • Milman N, Clausen J, Byg K-E. Iron status in 268 Danish women aged 18–30 years. Influence of menstruation, method of contraception, and iron supplementation. Ann Hematol 1998; 76: 13–9.
  • Danish National Board of Health. Recommendations about iron supplementation during pregnancy. Ugeskr Laeger 1992; 154: 3445.
  • Milman N, Byg K-E, Juul-Jørgensen B, Bentzon MW. Translation of analysis results between serum ferritin assays, Ferritin RIA Amersham™ and Abbott AxSYM™ Ferritin. Hematol 1999; 4: 179–84.
  • Milman N, Juul-Jorgensen B, Bentzon MW. Calibration of the abbott AxSYM® Ferritin kit using the WHO Human Liver Ferritin International Standard 80/602. Clin Chem Clin Biochem 1997; 35: 631–2.
  • Cook JD, Skikne B. Iron deficiency: definition and diagnosis. J Intern Med 1989; 226: 349–55.
  • Worwood M. Laboratory determination of iron status. In: Brock JH, Halliday JW, Pippard MJ, Powell LW, eds. Iron Metabolism in Health and Disease. London: W.B. Saunders, 1994: 449–76.
  • Milman N, Pedersen NS, Visfeldt J. Serum ferritin in healthy Danes: relation to marrow haemosiderin iron stores. Dan Med Bull 1983; 30: 115–20.
  • Rush D. Maternal nutritional deficiencies in industrialized countries. In: Baum D, ed. Births Risks. Nestle Nutrition Workshop Series 1993: 31, 83–94.
  • Anonymous. Do all pregnant women need iron? Br Med J 1978; 2: 1317.
  • Goodlin RC. Why treat ‘physiologic ‘anaemias of pregnancy? J Reprod Med 1982; 27: 639–46.
  • Hibbard BM. Iron and folate supplements during pregnancy: supplementation is valuable only in selected patients. Br Med J 1988; 297: 639–46.
  • van den Broek NR, Letsky EA, White SA, Shenkin A. Iron status in pregnant women: which measurements are valid? Br J Haematol 1998; 103: 817–24.
  • Milman N. Serum ferritin in Danes: Studies of iron status from infancy to old age, during blood donation and pregnancy. Int J Hematol 1996; 63: 103–35.
  • Skikne B, Baynes RD. Iron absorption. In: Brock JH, Halliday JW, Pippard MJ, Powell LW, eds. Iron Metabolism in Health and Disease. London: Saunders, 1994: 151–87.
  • Worwood M. Iron and the trace metals. In: Jacobs A, Worwood M, eds. Iron in Biochemistry and Medicine. London: Academic Press, 1974:335–67.
  • Meadows NJ, Graigner SL, Ruse W, Keeling PWN, Thompson RPH. Oral iron and the bioavailability of zinc. Br Med J 1983; 287: 1013–4.
  • Rossander-Hultén L, Brune M, Sandström B, Lönnerdal B, Hallberg L. Competitive inhibition of iron absorption by manganese and zinc in humans. Am J Clin Nutr 1991; 54: 152–6.
  • Solomons NW. Physiological interactions of minerals. In: Bodwell CE, Erdman JW, eds. Nutrient Interactions. New York: Marcel Dekker, 1988:115–48.
  • Lund EK, Wharf SG, Fairweather-Tait SJ, Johnson IT. Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers. Am J Clin Nutr 1999; 69: 250–5.
  • Wright RO, Shannon MW, Wright RJ, Hu H. Association between iron deficiency and low-level lead poisoning in an urban primary care clinic. Am J Public Health 2000; 89: 1049–53.
  • Akesson A, Berglund M, Schutz A, Bjellerup P, Bremme K, Vahter M. Cadmium exposure in pregnancy and lactation in relation to iron status. Am J Public Health 2002; 92: 284–7.
  • Svanberg B. Absorption of iron in pregnancy. Acta Obstet Gynecol Scand 1975; (Suppl) 48.
  • Puolakka J, Janne O, Pakarinen A, Jarvinen PA, Vihko R. Serum ferritin as a measure of iron stores during and after normal pregnancy with and without iron supplements. Acta Obstet Gynecol Scand 1980; (Suppl) 95: 43–51.
  • Foulkes J, Goldie DJ. The use of ferritin to assess the need for iron supplements in pregnancy. J Obstet Gynaecol 1982; 3: 11–6.
  • Romslo I, Haram K, Sagen N, Augensen K. Iron requirement in normal pregnancy as assessed by serum ferritin, serum transferrin saturation, and erythrocyte protoporfyrin determination. Br J Obstet Gynaecol 1983; 90: 101–7.
  • Taylor DJ, Mallen C, McDougall N, Lind T. Effect of iron supplementation on serum ferritin levels during and after pregnancy. Br J Obstet Gynaecol 1982; 89: 1011–7.
  • Galan P, Wainer R, De Benaze C, Hercberg S. Prevention de l’anemie ferriprive au cours de la grossesse: effet de la supplementation precoce en fer. In: Hercberg S, Galan P, Dupin H, eds. Recent Knowledge on Iron and Folate Deficiencies in the World. Paris: INSERM, 1990:615–21.
  • Eskeland E, Malterud K, Ulvik RJ, Hunskaar S. Iron supplementation in pregnancy: is less enough? Acta Obstet Gynecol Scand 1997; 76: 822–8.
  • Thomsen JK, Prien-Larsen JC, Devantier A, Fogh-Andersen N. Low dose iron supplementation does not cover the need for iron during pregnancy. Acta Obstet Gynecol Scand 1993; 72: 93–8.
  • Brise H. Influence of meals on iron absorption in oral iron therapy. Acta Med Scand 1962; 171: 39–45.
  • Kerr DNS, Davidson S. The prophylaxis of iron-deficiency anemia in pregnancy. Lancet 1958; 2: 483–8.
  • Kerr DNS, Davidson S. Gastrointestinal intolerance to oral iron preparations. Lancet 1958; 2: 489–92.
  • Sölvell L. Oral iron therapy. Side effects. In: Hallberg L, Harwerth, H-G, Vannotti A, eds. Iron Deficiency. Pathogenesis, Clinical Aspects, Therapy. London: Academic Press, 1970:573–83.
  • Milman N, Kirchhoff M. Iron stores in 1359, 30- to 60-year-old Danish women: evaluation by serum ferritin and hemoglobin. Ann Hematol 1992; 64: 22–7.
  • Milman N, Ibsen KK, Christensen JM. Serum ferritin and iron status in mothers and newborn infants. Acta Obstet Gynecol Scand 1987; 66: 205–11.
  • Andersen NL, Fagt S, Groth MV, Hartkopp HB, Møller A, Ovesen L et al. Dietary habits in Denmark 1995. Main results. Copenhagen: National Food Agency of Denmark, Publication no. 235, 1995.
  • Milman N, Byg K-E, Ovesen L. Iron status in Danes updated 1994. II: prevalence of iron deficiency and iron overload in 1319 Danish women aged 40–70 years. Influence of blood donation, alcohol intake, and iron supplementation. Ann Hematol 2000; 79: 612–21.
  • Trygg K, Lund-Larsen K, Sandstad B, Hoffman HJ, Jacobsen G, Bakketeig LS. Do pregnant smokers eat differently from pregnant non-smokers? Paediatr Perinat Epidemiol 1995; 9: 307–19.
  • Preziosi P, Prual A, Galan P, Daouda H, Boureima H, Hercberg S. Effect of iron supplementation on the iron status of pregnant women: consequences for the newborn. Am J Clin Nutr 1997; 66: 1178–82.
  • Hemminki E, Rimpela U. A randomized comparison of routine versus selective iron supplementation during pregnancy. J Am Coll Nutr 1991; 10: 3–10.
  • Milman N, Pedersen P, Ovesen L, Melsen GV, Fenger K. Frequency of the C282Y and H63D mutations of the haemochromatosis (HFE) gene in 2501 ethnic Danes. Ann Hematol 2004 [in press].

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