Techniques for the identification of genes involved in psychiatric disorders

References

• Kennedy D. Breakthrough of the year. Science 2003; 302: 2033
   PubMed Web of Science ®Google Scholar
• Anonymous The runners up. Science 2003; 302: 2039–2045
   PubMed Web of Science ®Google Scholar
• Caspi A, Sugden K, Moffitt T E, et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301: 386–389
   PubMed Web of Science ®Google Scholar
• Akil M, Kolachana B S, Rothmond D A, Hyde T M, Weinberger D R, Kleinman J E. Catechol-O-methyltransferase genotype and dopamine regulation in the human brain. The Journal of Neuroscience 2003; 23: 2008
   PubMed Web of Science ®Google Scholar
• Egan M F, Goldberg T E, Kolachana B S, et al. Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America 2001; 98: 6917–6922
   PubMed Web of Science ®Google Scholar
• Egan M F, Kojima M, Callicott J H, et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003; 112: 144–145
   PubMed Web of Science ®Google Scholar
• Stefansson H, Sigurdsson E, Steinthorsdottir V, et al. Neuregulin 1 and susceptibility to schizophrenia. American Journal of Human Genetics 2002; 71: 877–892
   PubMed Web of Science ®Google Scholar
• Millar J K, Wilson-Annan J C, Anderson S, et al. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Human Molecular Genetics 2000; 9: 1415–1423
   PubMed Web of Science ®Google Scholar
• Chumakov I, Blumenfeld M, Guerassimenko O, et al. Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America 2002; 99: 13675–13680
   PubMed Web of Science ®Google Scholar
• Straub R E, Jiang Y, MacLean C J, et al. Genetic variation in the 6p22.3 gene DTNBP1 the human ortholog of the mouse dysbindin gene is associated with schizophrenia. American Journal of Human Genetics 2002; 71: 337–348
   PubMed Web of Science ®Google Scholar
• St Clair D, Blackwood D, Muir W, et al. Association within a family of a balanced autosomal translocation with major mental illness. Lancet 1990; 336: 13–16
   PubMed Web of Science ®Google Scholar
• Efron D, Delatycki M B, de Silva M G, et al. A novel pericentric inversion of chromosome 3 cosegregates with a developmental–behavioural phenotype. Journal of Medical Genetics 2003; 40: E15
   Google Scholar
• Royer-Pokora B, Kunkel L M, Monaco A P, et al. Cloning the gene for an inherited human disorder –chronic granulomatous disease –on the basis of its chromosomal location. Nature 1986; 322: 32–38
   PubMed Web of Science ®Google Scholar
• Botstein D, Risch N. Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nature Genetics 2003; 33(Suppl)228–237
   PubMed Web of Science ®Google Scholar
• Wang S, Sun C E, Walczak C A, et al. Evidence for a susceptibility locus for schizophrenia on chromosome 6pter-p22. Nature Genetics 1995; 10: 41–46
   PubMed Web of Science ®Google Scholar
• Straub R E, MacLean C J, O'Neill F A, et al. A potential vulnerability locus for schizophrenia on chromosome 6p24–22: evidence for genetic heterogeneity. Nature Genetics 1995; 11: 287–293
   PubMed Web of Science ®Google Scholar
• Moises H W, Yang L, Kristbjarnarson H, et al. An international two-stage genome-wide search for schizophrenia susceptibility genes. Nature Genetics 1995; 11: 321–324
   PubMed Web of Science ®Google Scholar
• Maziade M, Bissonnette L, Rouillard E, et al. 6p24–22 region and major psychoses in the Eastern Quebec population. Le Groupe IREP. American Journal of Medical Genetics 1997; 74: 311–318
   PubMed Web of Science ®Google Scholar
• Lindholm E, Ekholm B, Shaw S, et al. A schizophreniasusceptibility locus at 6q25, in one of the world's largest reported pedigrees. American Journal of Human Genetics 2001; 69: 96–105
   PubMed Web of Science ®Google Scholar
• Schwab S G, Hallmayer J, Albus M, et al. A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings: support for loci on chromosome 10p and 6. Molecular Psychiatry 2000; 5: 638–649
   PubMed Web of Science ®Google Scholar
• Schizophrenia Linkage Collaborative Group for Chromosomes 3, 6 and 8. Additional support for schizophrenia linkage on chromosomes 6 and 8: a multicenter study. American Journal of Medical Genetics 1996; 67: 580–594
   PubMed Web of Science ®Google Scholar
• Blouin J L, Dombroski B A, Nath S K, et al. Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21. Nature Genetics 1998; 20: 70–73
   PubMed Web of Science ®Google Scholar
• Gurling H M, Kalsi G, Brynjolfson J, et al. Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21–22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3–24 and 20q12.1–11.23. American Journal of Human Genetics 2001; 68: 661–673
   PubMed Web of Science ®Google Scholar
• Kendler K S, MacLean C J, O'Neill F A, et al. Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families. American Journal of Psychiatry 1996; 153: 1534–1540
   PubMed Web of Science ®Google Scholar
• Lewis C M, Levinson D F, Wise L H, et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: schizophrenia. American Journal of Human Genetics 2003; 73: 34–48
   PubMed Web of Science ®Google Scholar
• Adams L J, Mitchell P B, Fielder S L, Rosso A, Donald J A, Schofield P R. A susceptibility locus for bipolar affective disorder on chromosome 4q35. American Journal of Human Genetics 1998; 62: 1084–1091
   PubMed Web of Science ®Google Scholar
• Badenhop R F, Moses M J, Scimone A, et al. Genetic refinement and physical mapping of a 2.3 Mb probable disease region associated with a bipolar affective disorder susceptibility locus on chromosome 4q35. American Journal of Medical Genetics 2003; 117B: 23–32
   PubMed Web of Science ®Google Scholar
• Willour V L, Zandi P P, Huo Y, et al. Genome scan of the fifty-six bipolar pedigrees from the NIMH genetics initiative replication sample: chromosomes 4, 7, 9, 18, 19, 20, and 21. American Journal of Medical Genetics 2003; 121B: 21–27
   PubMed Web of Science ®Google Scholar
• Friddle C, Koskela R, Ranade K, et al. Full-genome scan for linkage in 50 families segregating the bipolar affective disease phenotype. American Journal of Human Genetics 2000; 66: 205–215
   PubMed Web of Science ®Google Scholar
• McInnis M G, Lan T H, Willour V L, et al. Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12. Molecular Psychiatry 2003; 8: 288–298
   PubMed Web of Science ®Google Scholar
• Bennett P, Segurado R, Jones I, et al. The Wellcome trust UK–Irish bipolar affective disorder sibling-pair genome screen: first stage report. Molecular Psychiatry 2002; 7: 189–200
   PubMed Web of Science ®Google Scholar
• Blair I P, Adams L J, Badenhop R F, et al. A transcript map encompassing a susceptibility locus for bipolar affective disorder on chromosome 4q35. Molecular Psychiatry 2002; 7: 867–873
   PubMed Web of Science ®Google Scholar
• Collins F S, Guyer M S, Charkravarti A. Variations on a theme: cataloging human DNA sequence variation. Science 1997; 278: 1580–1581
   PubMed Web of Science ®Google Scholar
• Pritchard J K. Are rare variants responsible for susceptibility to complex diseases?. American Journal of Human Genetics 2001; 69: 124–137
   PubMed Web of Science ®Google Scholar
• Lohmueller K E, Pearce C L, Pike M, Lander E S, Hirschhorn J N. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nature Genetics 2003; 33: 177–182
   PubMed Web of Science ®Google Scholar
• Zapata C, Alvarez G. On Fisher's exact test for detecting gametic disequilibrium between DNA polymorphisms. Annals of Human Genetics 1997; 61: 71–77
   PubMed Web of Science ®Google Scholar
• Terwilliger J D, Ott J. Handbook of human genetic linkage. The Johns Hopkins University Press, Baltimore, MD 1994
   Google Scholar
• Jorde L B. Linkage disequilibrium as a gene mapping tool. American Journal of Human Genetics 1995; 56: 11–14
   PubMed Web of Science ®Google Scholar
• Spielman R S, McGinnis R E, Ewens W J. Transmission test for linkage disequilibrium: the insulin gene region and insulindependent diabetes mellitus (IDDM). American Journal of Human Genetics 1993; 52: 506–516
   PubMed Web of Science ®Google Scholar
• Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996; 273: 1516–1517
   PubMed Web of Science ®Google Scholar
• Risch N J. Searching for genetic determinants in the new millennium. Nature 2000; 405: 847–856
   PubMed Web of Science ®Google Scholar
• The International HapMap Consortium The International HapMap Project. Nature 2003; 426: 789–796
   PubMed Web of Science ®Google Scholar
• Neale B M, Sham P C. The future of association studies: gene-based analysis and replication. American Journal of Human Genetics 2004; 75: 353–362
   PubMed Web of Science ®Google Scholar
• Pericak-Vance M A, Bebout J L, Gaskell P C, Jr, et al. Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. American Journal of Human Genetics 1991; 48: 1034–1050
   PubMed Web of Science ®Google Scholar
• Corder E H, Saunders A M, Strittmatter W J, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993; 261: 921–923
   PubMed Web of Science ®Google Scholar
• Slooter A J, Cruts M, Kalmijn S, et al. Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study. Archives of Neurology 1998; 55: 964–968
   PubMedGoogle Scholar
• Grabe H J, Lange M, Wolff B, et al. Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden. Molecular Psychiatry, July 20 2004 [Epub ahead of print]
   Web of Science ®Google Scholar
• Gabriel S B, Schaffner S F, Nguyen H, et al. The structure of haplotype blocks in the human genome. Science 2002; 296: 2225–2229
   PubMed Web of Science ®Google Scholar
• Patil N, Berno A J, Hinds D A, et al. Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science 2001; 294: 1719–1723
   PubMed Web of Science ®Google Scholar
• van den Oord E J, Neale B M. Will haplotype maps be useful for finding genes?. Molecular Psychiatry 2004; 9: 227–236
   PubMed Web of Science ®Google Scholar
• Ke X, Cardon L R. Efficient selective screening of haplotype tag SNPs. Bioinformatics 2003; 19: 287–288
   PubMed Web of Science ®Google Scholar
• Carlson C S, Eberle M A, Rieder M J, Yi Q, Kruglyak L, Nickerson D A. Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. American Journal of Human Genetics 2004; 74: 106–120
   PubMed Web of Science ®Google Scholar
• Carlson C S, Eberle M A, Kruglyak L, Nickerson D A. Mapping complex disease loci in whole-genome association studies. Nature 2004; 429: 446–452
   PubMed Web of Science ®Google Scholar
• Kruglyak L. Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nature Genetics 1999; 22: 139–144
   PubMed Web of Science ®Google Scholar
• John S, Shephard N, Liu G, et al. Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites. American Journal of Human Genetics 2004; 75: 54–64
   PubMed Web of Science ®Google Scholar
• Freimer N, Sabatti C. The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology. Nature Genetics 2004; 36: 1045–1051
   PubMed Web of Science ®Google Scholar