Increased circulating concentrations of asymmetric dimethyl arginine (ADMA), an endogenous inhibitor of nitric oxide synthesis, in preeclampsia

References

• Roberts JM, Redman CWG. Preeclampsia: more than pregnancy-induced hypertension. Lancet 1993; 341: 1447–54.
   PubMed Web of Science ®Google Scholar
• Bernheim J. Hypertension in pregnancy. Nephron 1997; 76: 254–63.
   Google Scholar
• Cockel AP, Poston L. Flow mediated vasodilatation is enhanced in normal pregnancy but reduced in preeclampsia. Hypertension 1997; 30: 247–51.
   Google Scholar
• Sladek SM, Magness RR, Conrad KP Nitric oxide and pregnancy. Am J Physiol 1997; 272: R441–63.
   PubMed Web of Science ®Google Scholar
• Begum S, Yamasaki M, Mochizuki M. Urinary levels of nitric oxide metabolites in normal pregnancy and preeclampsia. J Obstet Gynaecol Res 1996; 22: 551–9.
   Google Scholar
• Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Eng J Med 1993; 329: 2002–12.
   PubMed Web of Science ®Google Scholar
• Vallance P, Leone A, Calver A, Collier J, Moncada S. Accumulation of an endogenous inhibitor of nitric oxide in chronic renal failure. Lancet 1992; 339: 572–5.
   Google Scholar
• Fickling SA, Williams D, Vallance P, Nussey SS, Whitley G St J. Plasma concentrations of endogenous inhibitor of nitric oxide synthesis in normal pregnancy and preeclampsia. Lancet 1993; 342: 242–3.
   Google Scholar
• Pettersson A, Uggla L, Backman V. Determination of methylated aminoacids in human plasma and urine by high-performance liquid chromatography. J Chromotogr B Biomed Sci Appl 1997; 692: 257–62.
   Google Scholar
• Halawa I, Baig S, Qureshi A. Use ofhigh performance liquid chromatography in defining the abnormalities in free amino acid patterns in the cerebrospinal fluid of patients with aseptic meningitis. Biomed Chromatogr 1991; 5: 216–20.
   Google Scholar
• Weiner CP, Martinez E, Zhu LK, Ghodsi A, Chestnut D. In vitro release of endothelium-derived relaxing factor by acethylcholine is increased during guinea pig pregnancy. Am J Obstet Gynecol 1989; 161: 1599–605.
   Google Scholar
• Pinto A, Sorentino R, Sorrentino P. Endothelial derived relaxing factor released by endothelial cells of human umbilical vessels and its impairment in pregnancy-induced hypertension. Am J Obstet Gynecol 1991; 164: 507–9.
   Google Scholar
• Silver RK, Kupferminc MJ, Russell TL, Adler L, Mullen TA, Caplan MS. Evaluation of nitric oxide as a mediator of severe preeclampsia. Am J Obstet Gynecol 1996; 175: 1013–17.
   PubMed Web of Science ®Google Scholar
• McCarthy AL, Woolfson RG, Shanti KR, Poston L. Abnormal endothelial cell function of resistance arteries from women with preeclampsia. Am J Obstet Gynecol 1993; 168: 1323–6.
   PubMed Web of Science ®Google Scholar
• Herlitz H, Pettersson A, Sigstrom L, Wennmalm A, Westberg G. The arginine-nitric oxide pathway in thrombotic microangiopathy. Scand J Urol Nephrol 1997; 31: 477–9.
   PubMed Web of Science ®Google Scholar
• Hishikawa K, Nakaki T, Kato R, Saruta T. L-arginine as an antihypertensive agent. J Cardiovasc Pharmacol 1992; 20 (Suppl 12): 196–7.
   Google Scholar
• Helmbrecht GD, Farhat MY, Lochbaum L, Brown HE, Yadgarova KT, Eglinton GS et al. L-arginine reverses the adverse pregnancy changes induced by nitric oxide synthase inhibition in the rat. Am J Obstet Gynecol 1996; 175: 800–5.
   PubMed Web of Science ®Google Scholar
• Fickling SA, Leone AM, Nussey SS, Vallance P, Whitley GJ. Synthesis of NG, NG dimethylarginine by human endothelial cells. Endothelium 1993; 1: 137–40.
   Google Scholar
• Hecker M, Mitchell JA, Harris HJ, Katsura M, Thiemermann C, Vane JR. Endothelial cells metabolize NG-monomethyl-L-argenine to L-citrulline and subsequently to L-arginine. Biochem Biophys Res Comm 1990; 167: 1037–43.
   PubMed Web of Science ®Google Scholar
• Paik WK, Kim S. Protein methylase I. Function and properties of the enzyme. J Biol Chem 1967; 243: 2108–14.21. Wang C, Lin J-M, Lazarides E. Méthylations of 70000-Da heat shock proteins in 3T3 cells: Alterations in arsenite treatment, by different stages of growth and by virus transformation. Arch Biochem Biophys 1992; 297: 169–75.
   Google Scholar
• Kakimoto Y, Akazawa S. Isolation and identification of NG, NG-dimethyl-arginine, mono-, di- and trimethyllysine, and glycosylgalactosyl- and galactosyl-hydroxylysine from human urine. J Biol Chem 1970; 245: 5751–8.
   PubMed Web of Science ®Google Scholar
• Desrosiers R, Tanguay RM. Methylation of drosphilia histones at proline, lysine and arginine residues during heat shock. J Biol Chem 1988; 263: 4686–92.
   PubMedGoogle Scholar
• Lou MF, Chang AC, Mahoney MJ. Dimethylarginines in human amniotic fluid. Clin Chem 1982; 28: 553–4.
   Google Scholar
• Lou MF. Human muscular dystrophy: elevation of urinary dimethylarginines. Science 1979; 203: 668–70.
   Google Scholar