Maternal serum of women with pre-eclampsia reduces trophoblast cell viability: evidence for an increased sensitivity to Fas-mediated apoptosis

References

• Roberts JM. Pregnancy related hypertension. In Creasy RK, Resnik R, eds. Maternal Fetal Medicine. Philadelphia: WB Saunders, 1998:883–92
   Google Scholar
• Elmer DB, Granai CO, Ball HO, et al. Persistence of gesta-tional trophoblastic disease for longer than 1 year following evacuation of hydatidiform mole. Obstet Gynecol 1993; 81:888–90
   PubMed Web of Science ®Google Scholar
• Lain KY, Roberts JM. Contemporary concepts of the patho-genesis and management of preeclampsia. J Am Med Assoc 2002;287:3183–6
   PubMed Web of Science ®Google Scholar
• Romero R, Lockwood C, Oyarzun E, et al. Toxemia: new con-cepts in an old disease. Semin Perinatol 1988;12:302–23
   PubMed Web of Science ®Google Scholar
• Gyongyossy A, Kelentey B. An experimental study of the effect of ischaemia of the pregnant uterus on the blood pressure. J Obstet Gynaecol Br Commonw 1958;65:624
   Google Scholar
• Hadori AA. Chronic uterine ischemia and reversible experimental 'toxemia of pregnancy'. Am J Obstet Gynecol 1967;97:597–607
   PubMedGoogle Scholar
• Page EW. The relation between hydatid moles, relative ischemia of the gravid uterus, and the placental origin of eclampsia. Am J Obstet Gynecol 1938;37:291–3
   Google Scholar
• Page EW. The physiology of hypertension in eclampsia. Am J Obstet Gynecol 1939;38:230–9
   Google Scholar
• Roberts JM. Endothelial dysfunction in preeclampsia. Semin Reprod Endocrinol 1998;16:5–15
   PubMedGoogle Scholar
• Chua S, Wilkins T, Sargent I, et al. Trophoblast deportation inpre-eclampticpregnancy. Br J Obstet Gynaecol 1991;98:973–9
   PubMedGoogle Scholar
• Johansen M, Redman CW, Wilkins T, et al. Trophoblast deportation in human pregnancy - its relevance for pre-eclampsia. Placenta 1999;20:531–9
   PubMed Web of Science ®Google Scholar
• Knight M, Redman CW, Linton EA, et al. Shedding of syncytiotrophoblast microvilli into the maternal circulation in pre-eclamptic pregnancies. Br J Obstet Gynaecol 1998; 105:632–40
   PubMedGoogle Scholar
• Sacks O, Sargent I, Redman C. An innate view of human pregnancy. Immunol Today 1999;20:114–18
   Google Scholar
• Redman CW, Sacks GP, Sargent IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999;180:499–506
   Google Scholar
• Redman CW, Sargent IL. Placental debris, oxidative stress and pre-eclampsia. Placenta 2000;21:597–602
   PubMed Web of Science ®Google Scholar
• Gervasi MT, Chaiworapongsa T, Pacora P, et al. Phenotypic and metabolic characteristics of monocytes and granulocytes in preeclampsia. Am J Obstet Gynecol 2001;185:792–7
   PubMed Web of Science ®Google Scholar
• Redman CW, Sargent IL. The pathogenesis of pre-eclampsia. Gynecol Obstet Fertil 2001;29:518–22
   PubMedGoogle Scholar
• von Dadelszen P, Hurst O, Redman CW. Supernatants from co-cultured endothelial cells and syncytiotrophoblast micro-villous membranes activate peripheral blood leukocytes in vitro. Hum Reprod 1999;14:919–24
   Google Scholar
• Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998;281:1305–8
   PubMed Web of Science ®Google Scholar
• Nagata S. Fas and Fas ligand: a death factor and its receptor. Adv Immunol 1994;57:129–44
   PubMed Web of Science ®Google Scholar
• Nagata S. Apoptosis by death factor. Cell 1997;88:355–65
   PubMed Web of Science ®Google Scholar
• Israels LG, Israels ED. Apoptosis. Stem Cells 1999;17:306–13
   PubMed Web of Science ®Google Scholar
• Buemi M, Allegra A, D'Anna R, et al. Is apoptosis cause of pre-eclampsia? Eur Rev Med Pharmacol Sci 1998;2:185–8
   PubMedGoogle Scholar
• Darmochwal-Kolarz D, Rolinski J, Leszczynska-Gorzelak B, et al. Fas antigen expression on the decidual lymphocytes of pre-eclamptic patients. Am J Reprod Immunol 2000; 43:197–201
   Google Scholar
• Darmochwal-Kolarz D, Leszczynska-Gorzelak B, Rolinski J, et al. The expression and concentrations of Fas/APO-1 (CD95) antigen in patients with severe pre-eclampsia. J Reprod Immunol 2001;49:153–64
   PubMed Web of Science ®Google Scholar
• DiFederico E, Genbacev O, Fisher SJ. Preeclampsia is associ-ated with widespread apoptosis of placental cytotrophoblasts within the uterine wall. Am J Pathol 1999;155:293–301
   Google Scholar
• Genbacev O, DiFederico E, McMaster M, et al. Invasive cytotrophoblast apoptosis in pre-eclampsia. Hum Reprod 1999;14 (Suppl 2):59–66
   PubMedGoogle Scholar
• Ishihara N, Matsuo H, Murakoshi H, et al. Increased apoptosis in the syncytiotrophoblast in human term placentas com-plicated by either preeclampsia or intrauterine growth retardation. Am J Obstet Gynecol 2002;186:158–66
   PubMed Web of Science ®Google Scholar
• Leung DN, Smith SC, To KF, et al. Increased placental apoptosis in pregnancies complicated by preeclampsia. Am J Obstet Gynecol 2001;184:1249–50
   PubMed Web of Science ®Google Scholar
• von Dadelszen P, Watson RW, Noorwali F, et al. Maternal neutrophil apoptosis in normal pregnancy, preeclampsia, and normotensive intrauterine growth restriction. Am J Obstet Gynecol 1999;181:408–14
   PubMed Web of Science ®Google Scholar
• Jerzak M, Bischof P. Apoptosis in the first trimester human placenta: the role in maintaining immune privilege at the maternal-foetal interface and in the trophoblast remodelling. Eur J Obstet Gynecol Reprod Biol 2002;100:138–42
   PubMedGoogle Scholar
• Mundle SD, Raza A. Defining the dynamics of self-assembled Fas-receptor activation. Trends Immunol 2002;23:187–94
   PubMedGoogle Scholar
• Selam B, Kayisli UA, Garcia-Velasco JA, et al. Regulation of fas ligand expression by IL-8 in human endometrium. J Clin EndocrinolMetab 2002;87: 3921–7
   Google Scholar
• Song J, Sapi E, Brown W, et al. Roles of Fas and Fas ligand during mammary gland remodeling. J Clin Invest 2000; 106:1209–20
   PubMedGoogle Scholar
• Song J, Rutherford T, Naftolin F, et al. Hormonal regulation of apoptosis and the Fas and Fas ligand system in human endometrial cells. Mol Hum Reprod 2002;8:447–55
   PubMedGoogle Scholar
• Redman CW. Platelets and the beginnings of preeclampsia. N Engll Med 1990;323:478–80
   PubMed Web of Science ®Google Scholar
• Lubega J. Thrombin receptor on the placental syncytio-trophoblastic plasma membrane. Ric Clin Lab 1990;20:203–8
   PubMedGoogle Scholar
• Reverdiau P, Jarousseau AC, Thibault O, et al. Tissue factor activity of syncytiotrophoblast plasma membranes and tumoral trophoblast cells in culture. Thromb Haemost 1995; 73:49–54
   PubMedGoogle Scholar
• Levine RJ, Esterlitz JR, Raymond EG, et al. Trial of Calcium for Preeclampsia Prevention (CPEP): rationale, design, and methods. Control Clin Trials 1996;17:442–69
   PubMedGoogle Scholar
• Berridge MV, Tan AS. Characterization of the cellular reduc-tion of 3 -( 4,5 -dimethylthiazd-2-y1) -2,5 -diphenyltarazolium bromide (MTT): subcellular localization, substrate depend-ence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys 1993;303:474–82
   PubMed Web of Science ®Google Scholar
• Williams J. Premature seperation of the normally implanted placenta. Surg Gynecol Obstet 1915;21:541–54
   Google Scholar
• Chesley LC, McFaul IE. Studies on survivinghuman placental tissue. I. A search for pressor and antidiuretic factor. Am J Obstet Gynecol 1949;58:159
   Google Scholar
• Hunter CA Jr, Howard WF. A pressor substance (hystero-tonin) occuring in toxemia. Am J Obstet Gyneco11960;79:838
   PubMed Web of Science ®Google Scholar
• Page EW, Cox AJ. Renal changes following toxaemias of late pregnancy. West J Surg 1983;46:463
   Google Scholar
• Tatum HJ, Mule JO. The hypertensive action of blood from preeclampsia. Am J Obstet Gynecol 1962;83:1028�34
   Google Scholar
• Pirani BB, MacOillivray I. The effect of plasma retransfusion on the blood pressure in the puerperium. Am J Obstet Gynecol
   Google Scholar
• Gant NF, Daley GL, Chand S, et al. A study of angiotensin II pressor response throughout primigravid pregnancy. J Clin Invest 1973;52:2682–9
   PubMed Web of Science ®Google Scholar
• Gant NF, Chand S, Whalley PJ, et al. The nature of pressor responsiveness to angiotensin II in human pregnancy. Obstet Gynecol 1974;43:854
   PubMed Web of Science ®Google Scholar
• Li C, Ansari R, Yu Z, et al. Definitive molecular evidence of renin�angiotensin system in human uterine decidual cells. Hypertension 2000;36:159�64
   Google Scholar
• Shah DM. Perinatal implications of maternal hypertension. Semin Pediatr Neurol 2001;8:108�19
   Google Scholar
• Talledo DE, Chesley LC, Zuspan FP. Renin-angiotensin system in normal and toxemic pregnancies. III. Differential sensitivity to angiotensin II and norepinephrine in toxemia of
   Google Scholar
• Zuspan FP. Catecholamines. Their role in pregnancy and the development of pregnancy-induced hypertension. J Reprod
   Google Scholar
• Krege JH, Katz VL. A proposed relationship between vaso-pressinase altered vasopressin and preeclampsia. Med Hypotheses 1990;31:283–7
   PubMed Web of Science ®Google Scholar
• McKinney ET, Shouri R, Hunt RS, et al. Plasma, urinary, and salivary 8-epi-prostaglandin f2alpha levels in normotensive and preeclamptic pregnancies. Am J Obstet Gynecol 2000; 183:874�7
   Google Scholar
• Clark BA, Halvorson L, Sachs B, et al. Plasma endothelin levels in preeclampsia: elevation and correlation with uric acid levels and renal impairment. Am J Obstet Gynecol 1992;166:962–8
   PubMed Web of Science ®Google Scholar
• Pedersen EB, Aalkjaer C, Christensen NJ, et al. Renin, angio-tensin II, aldosterone, catecholamines, prostaglandins and vasopressin. The importance of pressor and depressor factors for hypertension in pregnancy. Scand J Clin Lab Invest Suppl 1984;169:48–56
   PubMedGoogle Scholar
• Huppertz B, Frank HO, Kingdom JC, et al. Villous cyto-trophoblast regulation of the syncytial apoptotic cascade in the human placenta. Histochem Cell Biol 1998;110:495–508
   PubMed Web of Science ®Google Scholar
• Huppertz B, Frank HO, Kaufmann P. The apoptosis cascade - morphological and immunohistochemical methods for its visualization. Anat Embry ol (Berl) 1999;200:1–18
   Google Scholar
• Huppertz B, Frank HO, Reister F, et al. Apoptosis cascade progresses during turnover of human trophoblast: analysis of villous cytotrophoblast and syncytial fragments in vitro. Lab Invest 1999;79:1687–702
   PubMed Web of Science ®Google Scholar
• Reister F, Frank HO, Kingdom JC, et al. Macrophage-induced apoptosis limits endovascular trophoblast invasion in the uterine wall of preeclamptic women. Lab Invest 2001; 81:1143–52
   PubMed Web of Science ®Google Scholar
• Lea RG, Riley SC, Antipatis C, et al. Cytokines and the regulation of apoptosis in reproductive tissues: a review. Am J Reprod Immunol 1999;42:100–9
   PubMedGoogle Scholar
• Greer IA, Lyall F, Perera T, et al. Increased concentrations of cytokines interleukin-6 and interleukin-1 receptor antagonist in plasma of women with preeclampsia: a mechanism for endothelial dysfunction? Obstet Gynecol 1994;84:937–40
   PubMed Web of Science ®Google Scholar
• Teran E, Escudero C, Moya W, et al. Elevated C-reactive protein and pro-inflammatory cytokines in Andean women with pre-eclampsia. Int J Gynaecol Obstet 2001;75:243–9
   PubMed Web of Science ®Google Scholar
• Visser W, Beckmann I, Knook MA, et al. Soluble tumor necrosis factor receptor II and soluble cell adhesion molecule 1 as markers of tumor necrosis factor-alpha release in pre-eclampsia. Acta Obstet Gynecol Scand 2002;81:713–19
   PubMed Web of Science ®Google Scholar
• Aschkenazi S, Straszewski S, Verwer KM, et al. Differential regulation and function of the fas/fas ligand system in human trophoblast cells. Biol Reprod 2002;66:1853–61
   PubMed Web of Science ®Google Scholar
• Mor G, Gutierrez LS, Eliza M, et al. Fas-fas ligand system-induced apoptosis in human placenta and gestational trophob las tic disease. Am J Reprod Immunol 1998;40:89–94
   PubMed Web of Science ®Google Scholar