Chemokines in Lymphocyte Trafficking and Intestinal Immunity

REFERENCES

• Agace WW, Amara A, Roberts Al, Pablos JL, Thelen S, Uguccioni M, Li XY, Marsal J, Arenzana-Seisdedos F, Dulaunay T, Ebert EC, Moser R, Parker CM. (2000). Stromal derived factor-1 (SDF-1) is present in mucosal epithelia: relevance to HIV transmission and propagation. Curr Biol 10:325–328.
   PubMed Web of Science ®Google Scholar
• Agace WW, Higgins JM, Sadasivan B, Brenner MB, Parker CM. (2000). T-lymphocyte-epithelial-cell in-teractions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines. Curr Opin Cell Biol 12:563–568.
   PubMed Web of Science ®Google Scholar
• Agace WW, Roberts Al, Wu L, Greineder C, Ebert EC, Parker CM. (2000). Human intestinal lamina propria and intraepithelial lymphocytes express re-ceptors specific for chemokines induced by inflamma-tion. Eur J Immunol 30:819–826.
   PubMed Web of Science ®Google Scholar
• Andres PG, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, MacDer-mott RP, Podolsky DK, Reinecker HC. (2000). Mice with a selective deletion of the CC chemokine recep-tors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-asso-ciated Th2-type immune response in the intestine. J Immunol 164:6303–6312.
   Google Scholar
• Bargatze RF, Jutila MA, Butcher EC. (1995). Distinct roles of L-selectin and integrins alpha 4 beta 7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: the multistep model confirmed and refined. Immunity 3:99–108.
   PubMed Web of Science ®Google Scholar
• Bowman EP, Kuklin N, Youngman KR, Lazarus N, Kunkel EJ, Pan J, Greenberg HB, Butcher EC. (2002). The intestinal chemokine TECK (CCL25) at-tracts IgA antibody secreting cells. J Exp Med 195: 269–275.
   PubMed Web of Science ®Google Scholar
• Brandtzaeg P. Baekkevold ES, Farstad IN, Jahnsen FL, Johansen FE, Nilsen EM, Yamanaka T. (1999). Regional specialization in the mucosal immune sys- tern: what happens in the microcompartments? Im-munol Today 20:141–151.
   Google Scholar
• Brandtzaeg P. Farstad IN, Haraldsen G. (1999). Re-gional specialization in the mucosal immune system: primed cells do not always home along the same track. Immunol Today 20:267–277.
   Google Scholar
• Briskin M, Winsor-Hines D, Shyjan A, Cochran N, Bloom S, Wilson J, McEvoy LM, Butcher EC, Kassam N, Mackay CR, Newman W, Ringler DJ. (1997). Hu-man mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and asso-ciated lymphoid tissue. Am J Pathol 151:97–110.
   PubMed Web of Science ®Google Scholar
• Butcher EC. (1991). Leukocyte-endothelial cell rec-ognition: three (or more) steps to specificity and di-versity. Cell 67:1033–1036.
   PubMed Web of Science ®Google Scholar
• Butcher EC, Picker U. (1996). Lymphocyte horning and homeostasis. Science 272:60–66.
   PubMed Web of Science ®Google Scholar
• Butcher EC, Williams M, Youngman K, Rott L, Briskin M. (1999). Lymphocyte trafficking and re-gional immunity. Adv Immunol 72:209–253.
   PubMed Web of Science ®Google Scholar
• Cahill RN, Poskitt DC, Frost DC, Trnka Z. (1977). Two distinct pools of recirculating T lymphocytes: migratory characteristics of nodal and intestinal T lymphocytes. J Exp Med 145:420–428.
   PubMed Web of Science ®Google Scholar
• Campbell DJ, Butcher EC. (2002). Rapid acquisition of tissue-specific horning phenotypes by CD4+ T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med 195:135–141.
   PubMed Web of Science ®Google Scholar
• Cinamon G, Grabovsky V, Winter E, Franitza S, Fei-gelson S, Shamri R, Dwir O, Alon R. (2001). Novel chemokine functions in lymphocyte migration through vascular endothelium under shear flow. J Leukoc Biol 69:860–866.
   PubMed Web of Science ®Google Scholar
• Cook DN, Prosser DM, Forster R, Zhang J, Kuklin NA, Abbondanzo SJ, Niu XD, Chen SC, Manfra DJ, Wiekowski MT, Sullivan LM, Smith SR, Greenberg HB, Narula SK, Lipp M, Lira SA. (2000). CCR6 me-diates dendritic cell localization, lymphocyte homeo-stasis, and immune responses in mucosal tissue. Im-munity 12:495–503.
   Google Scholar
• Czinn SJ, Lamm ME. (1986). Selective chemotaxis of subsets of B lymphocytes from gut-associated lym-phoid tissue and its implications for the recruitment of mucosal plasma cells. J Immunol 136:3607–3611.
   Google Scholar
• Dwinell MB, Lugering N, Eckmann L, Kagnoff MF. (2001). Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithe-lial cells. Gastroenterology 120:49–59.
   PubMed Web of Science ®Google Scholar
• Farstad IN, Carlsen H, Morton HC, Brandtzaeg P. (2000). Immunoglobulin A cell distribution in the hu-man small intestine: phenotypic and functional char-acteristics. Immunology 101:354–363.
   PubMed Web of Science ®Google Scholar
• Farstad IN, Halstensen TS, Lazarovits Al, Norstein J, Fausa O, Brandtzaeg P. (1995). Human intestinal B-cell blasts and plasma cells express the mucosal horn-ing receptor integrin alpha 4 beta 7. Scand J Immunol 42:662–672.
   Google Scholar
• Fiocchi C. (1998). Inflammatory bowel disease: eti- ology and pathogenesis. Gastroenterology 115:182–205.
   PubMed Web of Science ®Google Scholar
• Forster R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M. (1996). A putative chemokine receptor, BER1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87:1037–1047.
   PubMed Web of Science ®Google Scholar
• Forster R, Schubel A, Breitfeld D, Kremmer E, Ren-ner-Muller I, Wolf E, Lipp M. (1999). CCR7 coordi-nates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99:23–33.
   Google Scholar
• Foxman EF, Kunkel EJ, Butcher EC. (1999). Inte-grating conflicting chemotactic signals: the role of memory in leukocyte navigation. J Cell Biol 147:577–588.
   PubMed Web of Science ®Google Scholar
• Griscelli C, Vassalli P. McCluskey RT. (1969). The distribution of large dividing lymph node cells in syn-geneic recipient rats after intravenous injection. J Exp Med 130:1427–1451.
   PubMedGoogle Scholar
• Gurish MF, Humbles A, Tao H, Finkelstein S, Boyce JA, Gerard C, Friend DS, Austen KF. (2002). CCR3 is required for tissue eosinophilia and larval cytotoxicity after infection with Trichinella spiralis. J Immunol 168:5730–5736.
   Google Scholar
• Hamann A, Andrew DP, Jablonski-Westrich D, Holzmann B, Butcher EC. (1994). Role of alpha 4-in-tegrins in lymphocyte horning to mucosal tissues in vivo. J Immunol 152:3282–3293.
   PubMed Web of Science ®Google Scholar
• Izadpanah A, Dwinell MB, Eckmann L, Varki NM, Kagnoff MF. (2001). Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mecha-nism for modulating mucosal immunity. Am J Physiol Gastrointest Liver Physiol 280:G710–G719.
   Google Scholar
• Kantele A, Zivny J, Hakkinen M, Elson CO, Mestecky J. (1999). Differential horning commitments of anti-gen-specific T cells after oral or parenteral immuni-zation in humans. J Immunol 162:5173–5177.
   PubMed Web of Science ®Google Scholar
• Kim CH, Rott L, Kunkel EJ, Genovese MC, Andrew DP, Wu L, Butcher EC. (2001). Rules of chemokine receptor association with T cell polarization in vivo. J Clin Invest 108:1331–1339.
   PubMed Web of Science ®Google Scholar
• Kunkel EJ, Boisvert J, Murphy K, Vierra MA, Genovese MC, Wardlaw AJ, Greenberg HB, Hodge MR, Wu L, Butcher EC, Campbell JJ. (2002). Expres-sion of the chemokine receptors CCR4, CCR5, and CXCR3 by human tissue-infiltrating lymphocytes. Am J Pathol 160:347–355.
   PubMed Web of Science ®Google Scholar
• Kunkel EJ, Butcher EC. (2002). Chemokines and the tissue-specific migration of lymphocytes. Immunity 16:1–4.
   PubMed Web of Science ®Google Scholar
• Kunkel EJ, Campbell JJ, Haraldsen G, Pan J, Boisvert J, Roberts Al, Ebert EC, Vierra MA, Goodman SC, Genovese MC, Wardlaw AJ, Greenberg HB, Parker CM, Butcher EC, Andrew DP, Agace WW. (2000). Lymphocyte CCR9 and epithelial TECK expression distinguish the small intestinal immune compart-ment: epithelial expression of tissue-specific chemo- kines as an organizing principle in regional immunity. J Exp Med 192:761–768.
   PubMed Web of Science ®Google Scholar
• Lehnert K, Print CG, Yang Y, Krissansen GW. (1998). MAdCAM-1 costimulates T cell proliferation exclusively through integrin alpha4beta7, whereas VCAM-1 and CS-1 peptide use alpha4betal : evi-dence for "remote" costimulation and induction of hyperresponsiveness to B7 molecules. Eur J Immunol 28:3605–3615.
   Google Scholar
• Lim SP, Leung E, Krissansen GW. (1998). The beta7 integrin gene (Itgb-7) promoter is responsive to TGF-b etal: defining control regions. Immunogenetics 48: 184–195.
   PubMed Web of Science ®Google Scholar
• Luster AD. (2001). Chemokines regulate lymphocyte homing to the intestinal mucosa. Gastroenterology 120:291–294.
   Google Scholar
• Luther SA, Cyster JG. (2001). Chemokines as regu-lators of T cell differentiation. Nat Immunol 2:102–107.
   PubMed Web of Science ®Google Scholar
• Luther SA, Tang HL, Hyman PL, Farr AG, Cyster JG. (2000). Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse. Proc Nall Acad Sci USA 97:12694–12699.
   PubMed Web of Science ®Google Scholar
• MacDermott RP. (1999). Chemokines in the inflam-matory bowel diseases. J Clin Immunol 19:266–272.
   PubMedGoogle Scholar
• McDermott MR, Bienenstock J. (1979). Evidence for a common mucosal immunologic system. I. Migration of B immunoblasts into intestinal, respiratory, and genital tissues. J Immunol 122:1892–1898.
   PubMed Web of Science ®Google Scholar
• McNeal MM, Barone KS, Rae MN, Ward RL. (1995). Effector functions of antibody and CD8+ cells in reso-lution of rotavirus infection and protection against reinfection in mice. Virology 214:387–397.
   PubMed Web of Science ®Google Scholar
• Middleton J, Neil S, Wintle J, Clark-Lewis I, Moore H, Lam C, Auer M, Hub E, Rot A. (1997). Transcytosis and surface presentation of IL-8 by venular endothe-lial cells. Cell 91:385–395.
   PubMed Web of Science ®Google Scholar
• Morteau O, Castagliuolo I, Mykoniatis A, Zacks J, Wlk M, Lu B, Pothoulakis C, Gerard NP, Gerard C. (2002). Genetic deficiency in the chemokine receptor CCR1 protects against acute Clostridium difficile toxin A enteritis in mice. Gastroenterology 122:725–733.
   Google Scholar
• Nagler-Anderson C. (2001). Man the barrierl Strate-gic defenses in the intestinal mucosa. Nat Rev Immu-nol 1:59–67.
   PubMed Web of Science ®Google Scholar
• Neutra MR, Mantis NJ, Kraehenbuhl JP. (2001). Col-laboration of epithelial cells with organized mucosal lymphoid tissues. Nat Immunol 2:1004–1009.
   PubMed Web of Science ®Google Scholar
• Okada T, Ngo VN, Ekland EH, Forster R, Lipp M, Littman DR, Cyster JG. (2002). Chemokine require-ments for B cell entry to lymph nodes and Peyer's patches. J Exp Med 196:65–75.
   PubMed Web of Science ®Google Scholar
• Pan J, Kunkel EJ, Gosslar U, Lazarus N, Langdon P. Broadwell K, Vierra MA, Genovese MC, Butcher EC, Soler D. (2000). A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mu-cosal tissues. J Immunol 165:2943–2949.
   Google Scholar
• Papadakis KA, Prehn J, Moreno ST, Cheng L, Kour-oumalis EA, Deem R, Breaverman T, Ponath PD, An-drew DP, Green PH, Hodge MR, Binder SW, Targan SR. (2001). CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease. Gastroenterology 121:246–254.
   PubMed Web of Science ®Google Scholar
• Papadakis KA, Prehn J, Nelson V, Cheng L, Binder SW, Ponath PD, Andrew DP, Targan SR. (2000). The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. J Immunol 165:5069–5076.
   PubMed Web of Science ®Google Scholar
• Papadakis KA, Targan SR. (2000). The role of che-mokines and chemokine receptors in mucosal inflam-mation. Inflamm Bowel Dis 6:303–313.
   PubMedGoogle Scholar
• Reinecker HC, Loh EY, Ringler DJ, Mehta A, Rom-beau JL, MacDermott RP. (1995). Monocyte-chemoattractant protein 1 gene expression in intesti-nal epithelial cells and inflammatory bowel disease mucosa. Gastroenterology 108:40–50.
   PubMed Web of Science ®Google Scholar
• Shaw SK, Brenner MB. (1995). The beta 7 integrins in mucosal homing and retention. Semin Immunol 7: 335–342.
   PubMedGoogle Scholar
• Shibahara T, Wilcox JN, Couse T, Madara JL. (2001). Characterization of epithelial chemoat-tractants for human intestinal intraepithelial lympho-cytes. Gastroenterology 120:60–70.
   PubMed Web of Science ®Google Scholar
• Smith JB, McIntosh GH, Morris B. (1970). The traffic of cells through tissues: a study of peripheral lymph in sheep. J Anat 107:87–100.
   PubMed Web of Science ®Google Scholar
• Smith PD, Meng G, Sellers MT, Rogers TS, Shaw GM. (2000). Biological parameters of HIV-1 infection in primary intestinal lymphocytes and macrophages. J Leukoc Biol 68:360–365.
   PubMed Web of Science ®Google Scholar
• Sprent J. (1980). Antigen-induced selective seques-tration of T lymphocytes: role of the major histocom-patibility complex. Monogr Allergy 16:233–244.
   PubMedGoogle Scholar
• Springer TA. (1995). Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigra-tion. Annu Rev Physiol 57:827–872.
   Google Scholar
• Stagg AJ, Kamm MA, Knight SC. (2002). Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin. Eur J Immunol 32:1445–1454.
   PubMed Web of Science ®Google Scholar
• Streeter PR, Berg EL, Rouse BT, Bargatze RF, Butcher EC. (1988). A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature 331:41–46.
   PubMed Web of Science ®Google Scholar
• Strober W, Kelsall B, Fuss I, Marth T, Ludviksson B, Ehrhardt R, Neurath M. (1997). Reciprocal IFN-gamma and TGF-beta responses regulate the occur-rence of mucosal inflammation. Immunol Today 18: 61–64.
   PubMedGoogle Scholar
• Szabo MC, Butcher EC, McEvoy LM. (1997). Spe-cialization of mucosal follicular dendritic cells re- vealed by mucosal addressin-cell adhesion mol-ecule-1 display. J Immunol 158:5584–5588.
   Google Scholar
• Uehara S, Grinberg A, Farber JM, Love PE. (2002). A role for CCR9 in T lymphocyte development and mi-gration. J Immunol 168:2811–2819.
   PubMed Web of Science ®Google Scholar
• Uguccioni M, Gionchetti P. Robbiani DF, Rizzello F, Peruzzo S, Campieri M, Baggiolini M. (1999). In-creased expression of IP-10, IL-8, MCP-1, and MCP-3 in ulcerative colitis. Am J Pathol 155:331–336.
   PubMed Web of Science ®Google Scholar
• Varona R, Villares R, Carramolino L, Goya I, Zabal-los A, Gutierrez J, Torres M, Martinez A, Marquez G. (2001). CCR6-deficient mice have impaired leuko-cyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses. J Clin Invest 107:R37–R45.
   Google Scholar
• Wagner N, Lohler J, Kunkel EJ, Ley K, Leung E, Krissansen G, Rajewsky K, Muller W. (1996). Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature 382:366–370.
   PubMed Web of Science ®Google Scholar
• Wang W, Soto H, Oldham ER, Buchanan ME, Homey B, Catron D, Jenkins N, Copeland NG, Gilbert DJ, Nguyen N, Abrams J, Kershenovich D, Smith K, Mc-Clanahan T, Vicari AP, Zlotnick A. (2000). Identifi-cation of a novel CC chemokine (CCL28) which binds CCR10 (GPR2). J Biol Chem. 275: 22313–22323.
   Google Scholar
• Warnock RA, Campbell JJ, Dorf ME, Matsuzawa A, McEvoy LM, Butcher EC. (2000). The role of chemo-kines in the microenvironmental control of T versus B cell arrest in Peyer's patch high endothelial venules. J Exp Med 191:77–88.
   PubMed Web of Science ®Google Scholar
• Weisz-Carrington P. Roux ME, McWilliams M, Phil-lips-Quagliata JM, Lamm ME. (1979). Organ and isotype distribution of plasma cells producing specific antibody after oral immunization: evidence for a gen-eralized secretory immune system. J Immunol 123: 1705–1708.
   Google Scholar
• Wurbel M-A, Philippe J-M, Nguyen C, Victorero G, Freeman T, Wooding P, Miazek A, Mattel M-G, Ma-lissen M, Jordan BR, Malissen B, Carrie A, Naquet P. (2000). The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK re-ceptor CCR9. Eur J Immunol 30:262–271.
   PubMedGoogle Scholar
• Wurbel MA, Malissen M, Guy-Grand D, Meffre E, Nussenzweig MC, Richelme M, Carrier A, Malissen B. (2001). Mice lacking the CCR9 CC-chemokine recep-tor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gam-madelta(+) gut intraepithelial lymphocytes. Blood 98:2626–2632.
   PubMed Web of Science ®Google Scholar
• Yang SK, Eckmann L, Panja A, Kagnoff MF. (1997). Differential and regulated expression of C-X-C, C-C, and C-chemokines by human colon epithelial cells. Gastroenterology 113:1214–1223.
   PubMed Web of Science ®Google Scholar
• Yoshie O, Imai T, Nomiyama H. (2001). Chemokines in immunity. Adv Immunol 78:57–110.
   PubMed Web of Science ®Google Scholar
• Zabel BA, Agace WW, Campbell JJ, Heath HM, Par-ent D, Roberts Al, Ebert EC, Kassam N, Qin S, Zovko M, LaRosa GJ, Yang LL, Soler D, Butcher EC, Ponath PD, Parker CM, Andrew DP. (1999). Human G pro-tein-coupled receptor GPR-9-6/CC chemokine recep-tor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J Exp Med 190:1241–1256.
   PubMed Web of Science ®Google Scholar