Ischemia-Reperfusion: Mechanisms of Microvascular Dysfunction and the Influence of Risk Factors for Cardiovascular Disease

References

• Arndt H, Smith CW, Granger DN. (1993). Leukocyte- endothelial cell adhesion in spontaneously hypertensive and normotensive rats. Hypertension 321: 667–673.
   Google Scholar
• Banda MA, Lefer DJ, Granger DN. (1997). Postischemic endothelium-dependent vascular reactivity is preserved in adhesion molecule-deficient mice. Am J Physiol 273:H2721–H2725.
   Google Scholar
• Bauer P, Russell EVI, Granger DN. (1999). Role of endotoxin in intestinal reperfusion-induced expres-sion of E-selectin. Am J Physiol 276:G479–G484.
   Google Scholar
• Engler RL, Schrnid-Schonbein GW. (1995). Leuko-cytes in capillary networks. In: Physiology, and Pathophysiology of Leukocyte Adhesion (DN Granger and GW Schmid-Schonbein, Eds.) New York. Oxford University Press, 339-358.
   Google Scholar
• Eppihimer MJ, Russell J, Anderson DC, Epstein CJ, Laroux S, Granger DN. (1997). Modulation of P-selectin expression in the post-ischemic intestinal mi-crovasculature. Am J Physiol 273:G1326–G1332.
   Google Scholar
• Flavahan NA. (1992). Atherosclerosis or lipoprotein-induced endothelial dysfunction. Circulation 85: 1927–1938.
   PubMed Web of Science ®Google Scholar
• Gerritsen ME, Shen CP, Atkinson WJ, Padgett RC, Gimbrone MA, Milstone DS. (1996). Microvascular endothelial cells from E-selectin deficient mice form tubes in vitro. Lab Invest 75:175–184.
   PubMedGoogle Scholar
• Grace PA, Mathie RT. (1999). Ischemia-reperfusion injury. Blackwell Science, London,
   Google Scholar
• Granger DN. (1988). Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 255:H1269–H1275.
   Google Scholar
• Granger DN, Benoit JN, Suzuki M, Grisham MB. (1989). Leukocyte adherence to venular endothelium during ischemia-reperfusion. Am J Physiol 257:G683– G688.
   Google Scholar
• Granger DN, Rutili G, McCord JM. (1981). Superox-ide radicals in feline intestinal ischemia. Gastroenter-ology 81:22–29.
   PubMed Web of Science ®Google Scholar
• Grisham MB, Granger DN, Lefer DL. (1998). Modu-lation of leukocyte-endothelial interactions by reac-tive metabolites of oxygen and nitrogen: relevance to
   Google Scholar
• Grisham MB, Hernandez LA, Granger DN. (1986). Xanthine oxidase and neutrophil infiltration in intes-
   Google Scholar
• Harris NR, Granger DN. (1996). Neutrophil enhance-ment of reperfusion-induced capillary fluid filtration associated with hypercholesterolemia. Am J Physiol
   Google Scholar
• Harris NR, Granger DN. (1996). Mechanisms under-lying enhanced capillary filtration induced by platelet
   Google Scholar
• Harrison DG. (1997). Cellular and molecular mecha- nisms of endothelial cell dysfunction. J Clin Invest 100:2153–2157.
   Google Scholar
• Henninger DD, Gerritsen ME, Granger DN. (1997). Low-density lipoprotein receptor knockout mice ex-hibit exaggerated microvascular responses to inflam-matory stimuli. Circ Res 81:274–281.
   Google Scholar
• Hone Y, Wolf R, Anderson DC, Granger DN. (1997). Hepatic leukostasis and hypoxic stress in adhesion molecule deficient mice after gut ischemia-reperfusion. J Clin Invest 99:781–788.
   Google Scholar
• Hone Y, Wolf R, Flores SC, McCord ym, Epstein CJ, Granger DN. (1998). Transgenic mice with increased copper/zinc-superoxide dismutase activity are resis-tant to hepatic leukostasis and capillary no-reflow af-ter gut ischemia/reperfusion. Circ Res 83:691-696. Ichikawa H, Flores S, Kvietys PR, Wolf RE, Yoshi-kawa T, Granger DN, Aw TY. (1997). Molecular mechanisms of anoxia/reoxygenation-induced neu-trophil adherence to cultured endothelial cells. Circ Res 81:922–931.
   Google Scholar
• Inauen W, Granger DN, Meininger CJ, Schelling ME, Granger HJ, Kvietys PR. (1990). Anoxia-reoxygenation-induced, neutrophil-mediated endo-thelial cell injury: role of elastase. Am J Physiol 259:H925–H931.
   Google Scholar
• Inauen W, Granger DN, Meininger DJ, Schelling MD, Granger HJ, Kvietys PR. (1990). An in vitro model of ischemia-reperfusion induced microvascular injury. Am J Physiol 259:G134–G139.
   Google Scholar
• Inauen W, Payne DK, Kvietys PR, Granger DN. (1990). Hypoxia/reoxygenation increases the perme-ability of endothelial cell monolayers: role of oxygen radicals. Free Radic Biol Med 9:219–223.
   Google Scholar
• Inauen W, Payne DK, Kvietys PR, Granger DN. (1990). Hypoxia/reoxygenation increases the permeability of endothelial cell monolayers: role of oxygen radicals. Free Radic Biol Med 9:219–223.
   Google Scholar
• Kimura M, Kurose I, Russell J, Granger DN. (1997). Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolemic rats. Arteriosclero-sis Thromb and Vasc Biol 17:1521–1526.
   PubMed Web of Science ®Google Scholar
• Kokura S, Wolf RE, Yoshikawa T, Granger DN, Aw TY. (1999). Molecular mechanisms of neutrophil-endothelial cell adhesion induced by redox imbal-ance. Circ Res 84:516–524.
   PubMed Web of Science ®Google Scholar
• Komatsu S, Panes J, Russell ym, Anderson DC, Muzy-kantov VR, Miyasaka M, Granger DN. (1997). Ef-fects of chronic arterial hypertension on constitutive and induced intercellular adhesion molecule-1 ex-pression in vivo. Hypertension 29:683–689.
   Google Scholar
• Kubes P, Granger DN. (1996). Leukocyte-endothelial cell interactions invoked by mast cells. Cardiovasc Res 32:699–708.
   PubMedGoogle Scholar
• Kubes P, Kurose I, Granger DN. (1994). Nitric oxide donors prevent integrin-induced leukocyte adhesion, but not P-selectin-dependent rolling in postischemic venules . Am J Physiol 267:H931–H937.
   Google Scholar
• Kubes P, Suzuki M, Granger DN. (1991). Nitric ox-ide: An endogenous modulator of leukocyte adhesion. Proc Nat Acad Sci 88:4651–4655.
   Google Scholar
• Kurose I, Anderson DC, Miyasaka M, Tamatani T, Paulson JC, Todd RF, Rusche JR, Granger DN.(1994 ) . Molecular determinants of rep erfusio n - induced leukocyte adhesion and vascular protein leakage. Circ Res 74:336–343.
   Google Scholar
• Kurose I, Argenbright LW, Anderson DC, Tolley J, Miyasaka M, Harris N, Granger DN. (1997). Reper-fusion-induced leukocyte adhesion and vascular pro-tein leakage in normal and hypercholesterolemic rats. Am J Physiol 42:H854–H860.
   Google Scholar
• Kurose I, Argenbright LW, Wolf R, Liao L, Granger DN. (1997). Ischemia/reperfusion-induced microvas-cular dysfunction: role of oxidants and lipid media-tors. Am J Physiol 272:H2976–H2982.
   Google Scholar
• Kurose I, Wolf R, Cerwinka W, Granger DN. (1999). Microvascular responses to ischemia/reperfusion in normotensive and hypertensive rats. Hypertension (in press).
   Google Scholar
• Kurose I, Wolf R, Grisham MB, Granger DN. (1994). Modulation of ischemia/reperfusion-induced micro-vascular dysfunction by nitric oxide. Cir Res 74:376–382.
   PubMed Web of Science ®Google Scholar
• Kurose I, Wolf RE, Grisham MB, Granger DN. (1998). Hypercholesterolemia enhances oxidant pro-duction in mesenteric venules exposed to ischemia-reperfusion. Arterioscler Thromb Vasc Biol 18:1583–1588.
   PubMed Web of Science ®Google Scholar
• Kvietys PR, Granger DN. (1997). Endothelial cell monolayers as a tool for studying microvascular pathophysiology. Am J Physiol 273:G1189–G1199.
   Google Scholar
• Lalor P, Nash GB. (1995). Adhesion of flowing leu-kocytes to immobilized platelets. Brit J Haematol 89: 725–734.
   PubMed Web of Science ®Google Scholar
• Lehr HA, Guhlrnann A, Nolte D, Keppler D, Messmer K. (1991). Leukotrienes as meditors in ischemia-reperfusion injury in a microcirculation model of the hamster. J Clin Invest 87:2036–2041.
   PubMed Web of Science ®Google Scholar
• Liao L, Aw TY, Kvietys PR, Granger DN. (1995). Oxidized low density lipoprotein induced microvas-cular dysfunction: Dependence on oxidation proce-dure. Arteriosclerosis Thrombosis Vasc Biol 15:2305–2311.
   PubMed Web of Science ®Google Scholar
• Liao L, Harris N, Granger DN. (1996). Oxidized low density lipoproteins and microvascular responses to ischemia-reperfusion. Am J Physiol 271:H2508–H2514.
   Google Scholar
• Liao L, Starzyk RM, Granger DN. (1997). Molecular determinants of oxidized LDL-induced leukocyte ad-hesion and microvascular dysfunction. Arteriosclero-sis Thromb Vasc Biol 17:437–44.
   Google Scholar
• Mori N, Hone Y, Gerritsen ME, Granger DN. (1999). Ischemia-reperfusion induced microvascular re-sponses in LDLreceptor-/- mice. Am J Physiol 276:H1647–H1654.
   Google Scholar
• Oliver M, Specian RD, Perry MA, Granger DN. (1991). Morphological assessment of leukocyte-endothelial cell interactions in mesenteric venules subjected to ischemia and reperfusion. Inflammation 15:331–346.
   PubMed Web of Science ®Google Scholar
• Panes J, Kurose I, Rodriguez-Vaca D, Anderson DC, Miyasaka M, Tso P, Granger DN. (1996). Diabetes exacerbates inflammatory responses to ischemia-reperfusion. Circulation 93:161–167.
   Google Scholar
• Ratych RE, Chuknyiska RS, Bulldey GB. (1987). The primary localization of free radical generation after anoxia/reoxygenation in isolated endothelial cells. Surgery 102:122–131.
   PubMed Web of Science ®Google Scholar
• Salas A, Panes J, Elizalde JL, Casadevall M, Anderson DC, Granger DN, Pique ym. (1998). Mechanisms re-sponsible for enhanced inflammatory response to ischemia-reperfusion in diabetes. Am J Physiol 275: 1773–1781.
   Google Scholar
• Salas A, Panes J, Elizalde JL, Granger DN, Pique ym. (1999). Reperfusion-induced oxidative stress in dia-betes: Cellular and enzymatic sources. J Leuk Biol (in press).
   Google Scholar
• Schmid-Schonbein GW, Seiffge D, DeLano FA, Shen K, Zweifach BW. (1991). Leukocyte counts and ac-tivation in spontaneously hypertensive and normo-tensive rats. Hypertension 17:323–330.
   PubMed Web of Science ®Google Scholar
• Skalak R, Skalak TC. (1995). Flow behavior of leu-kocytes in small tubes. In: Physiology, and Patho-physiology of Leukocyte Adhesion (DN Granger and GW Schmid-Schonbein, Eds.) New York. Oxford University Press, 97-115.
   Google Scholar
• Steinberg HO, Bayazeed B, Hook G, Johnson A, Cro-nin J, Baron AD. (1997). Endothelial dysfunction is associated with cholesterol levels in the high normal range in humans. Circulation 96:3287–3293.
   PubMed Web of Science ®Google Scholar
• Suzuki H, DeLano FA, Parks DA, Jamshidi N, Granger DN, Ishii H, Suematsu M, Zweifach BW, Schmid-Schonbein GW. (1998). Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats. Proc Nat Acad Sci 95:4754–4759.
   PubMed Web of Science ®Google Scholar
• Suzuki M, Grisham MB, Granger DN. (1991). Leu-kocyte-endothelial cell adhesive interactions: role of xanthine oxidase-derived oxidants. J Leuk Biol 50: 488–494.
   Google Scholar
• Suzuki M, Inauen W, Kvietys P, Grisham MB, Mein-inger C, Schelling ME, Granger HJ, Granger DN. (1989) . Superoxide mediates rep erfusion -in duce d leukocyte-endothelial cell interactions. Am J Physiol 257:H1740–H1745.
   Google Scholar
• Suzuki H, Schmid-Schonbein GW, Suematsu M, DeLano FA, Forrest MJ, Miyasaka M, Zweifach BW. (1994). Impaired leukocyte-endothelial cell interac-tion in spontaneously hypertensive rats. Hypertension 24:719–727.
   PubMed Web of Science ®Google Scholar
• Swei A, Lacy F, DeLano FA, Schmid-Schonbein GW. (1997). Oxidative stress in the Dahl hypertensive rat. Hypertension 30:1628–1633.
   PubMed Web of Science ®Google Scholar
• Terada LS. (1996). Hypoxia-reoxygenation increases 0-2 efflux which injures endothelial cells by an extra-cellular mechanism. Am J Physiol 270:H945–H950.
   Google Scholar
• Vollmer B, Glasz J, Menger MD, Messmer K. (1995). Leukocytes contribute to hepatic ischemia/reperfusion via ICA1VI-1 mediated venular adherence. Surgery 117: 195–200.
   Google Scholar
• White CR, Darley-Usmar V, Berrington WR, McAd-ams M, Gore JZ, Thompson JA, Parks DA, Tarpey 1VEVI, Freeman BA. (1996). Circulating plasma xan-thine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits. Proc Nat Acad Sci USA 93:8745–8749.
   PubMed Web of Science ®Google Scholar
• Yokoyarna S, Korthuis RJ, Benoit JN. (1996). Hyp-oxia-reoxygenation impairs endothelium-dependent relaxation in isolated rat aorta. Am J Physiol 270: R1126–1131.
   Google Scholar
• Yoshida N, Granger DN, Anderson DC, Rothlein R, Lane C, Kvietys PR. (1992). Anoxia/reoxygenation- induced neutrophil adherence to cultured endothelial cells. Am J Physiol 252:H1891—H1898.
   Google Scholar
• Zibari GB, Brown MF, Burney DL, Granger N, Mc-Donald JC. (1998). Role of P-selectin in the recruit-ment of leukocytes in mouse liver exposed to ischemia and reperfusion. Transplantation Proc 30:2327–233 0 .
   PubMed Web of Science ®Google Scholar
• Zimmerman BJ, Granger DN. (1990). Reperfusion-induced leukocyte infiltration: role of elastase. Am J Physiol 259:H390—H394.
   Google Scholar
• Zweier JL, Kuppusamy P, Thompson-Gorman S, Munk D, Lutty GA. (1994). Measurement and char-acterization of free radical generation in reoxygenated human endothelial cells. Am J Physiol 266:C700—C708.
   Google Scholar