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Review Article

Determinants of Endothelial Cell Phenotype in Venules

, &
Pages 67-80 | Received 15 Jun 1999, Accepted 29 Sep 1999, Published online: 14 Aug 2009

REFERENCES

  • Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U, Risau W, Klein R. (1999). Roles of ephrinB ligands and EphB receptors in cardiovascu-lar development: demarcation of arterial/venous do-mains, vascular morphogenesis, and sprouting an-giogenesis. Genes Dev 13:295–306.
  • Ager A. (1997). Regulation of lymphocyte migration into lymph nodes by high endothelial venules. Bio-chem Soc Trans 25:421–428.
  • Aird WC, Edelberg JM, Weiler-Guettler H, Simmons WW, Smith TW, Rosenberg RD. (1997). Vascular bed-specific expression of an endothelial cell gene is programmed by the tissue microenvironrnent. J Cell Biol 138:1117–1124.
  • Antohe F, Heltianu C, Sirnionescu N. (1986). Fur-ther evidence for the distribution and nature of his-tamine receptors on microvascular endothelium. Mi-crocirc Endothelium Lymphatics 3:163–185.
  • Antonelli-Orlidge A, Saunders KB, Smith SR, D'Amore PA. (1989). An activated form of trans-forming growth factor beta is produced by cocul-tures of endothelial cells and pericytes. Proc Natl Acad Sci USA 86:4544–4548.
  • Baez S. (1977). Microvascular terminology. In "Mi-crocirculation" (Kaley G, Attura BM, eds.) Univer-sity Park Press. Baltimore, MD.
  • Baldwin AL, Thurston G, al Naemi H. (1998). In-hibition of nitric oxide synthesis increases venular permeability and alters endothelial actin cytoskele-ton. Am J Physiol 274:H1776–H1784.
  • Baluk P, Bolton P, Hirata A, Thurston G, McDonald DM. (1998). Endothelial gaps and adherent leuko-cytes in allergen-induced early- and late-phase plasma leakage in rat airways. Am J Pathol 152: 1463–1476.
  • Baluk P, Thurston G, Murphy TJ, Bunnett NW, Mc-Donald DM. (1999). Neurogenic plasma leakage in mouse airways. Br J Pharmacol 126:522–528.
  • Beck L, Jr., D'Arnore PA. (1997). Vascular devel-opment: cellular and molecular regulation. FASER J 11:365–373.
  • Benjamin LE, Hemo I, Keshet E. (1998). A plastic-ity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125:1591–1598.
  • Bowden JJ, Baluk P, Lefevre PM, Vigna SR, McDon-ald DM. (1996). Substance P (NK1) receptor irn-munoreactivity on endothelial cells of the rat tra-cheal mucosa. Am J Physiol 270:L404–L414.
  • Bowden JJ, Garland AM, Baluk P, Lefevre P, Grady EF, Vigna SR, Bunnett NW, McDonald DM. (1994). Direct observation of substance P-induced internal-ization of neurokinin 1 (NK1) receptors at sites of inflammation. Proc Natl Acad Sci USA 91:8964–8968.
  • Braverman "VI, Yen A. (1977). Ultrastructure of the capillary loops in the dermal papillae of psoriasis. J Invest Dermatol 68:53–60.
  • Clark ER, Clark EL. (1932). Observations on living preformed blood vessels as seen in a transparent chamber inserted into the rabbit's ear. Am J Anat 49:441–477.
  • Clark ER, Clark EL. (1939). Microscopic observa-tions on the growth of blood capillaries in the living mammal. Am J Anat 64:251–301.
  • Clark ER, Clark EL. (1940). Microscopic observa-tions on the extra-endothelial cells of living mam-malian blood vessels. Am J Anat 66:1–49.
  • Cotran RS, Girnbrone MA, Jr., Bevilacqua MP, Men-drick DL, Pober JS. (1986). Induction and detection of a human endothelial activation antigen in vivo. J Exp Med 164:661–666.
  • Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno J, Radziejewski C, Mai-sonpierre PC, Yancopoulos GD. (1996). Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 87:1161–1169.
  • Detmar M, Brown LF, Schon MP, Elicker BM, Velasco P, Richard L, Fukurnura D, Monsky W, Claffey KP, Jain RK. (1998). Increased microvascu-lar density and enhanced leukocyte rolling and ad-hesion in the skin of VEGF transgenic mice. J Invest Dermatol 111:1–6.
  • Dickson MC, Martin JS, Cousins FM, Kulkarni AB, Karlsson S, Akhurst RJ. (1995). Defective haema-topoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development 121: 1845–1854.
  • Drake CJ, Little CD. (1995). Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascular-ization. Proc Natl Acad Sci USA 92:7657–7661.
  • Eppihimer MJ, Wolitzky B, Anderson DC, Labow MA, Granger DN. (1996). Heterogeneity of expres-sion of E- and P-selectins in vivo. Circ Res 79:560–569.
  • Erlansson M, Svensjo E, Bergqvist D. (1989). Leu-kotriene B4-induced permeability increase in post-capillary venules and its inhibition by three different antiinflammatory drugs. Inflammation 13:693–705.
  • Feletou M, Bonnardel E, Canet E. (1996). Bradyki-nin and changes in microvascular permeability in the hamster cheek pouch: role of nitric oxide. Br J Pharmacol 118:1371–1376.
  • Ferrara N, Davis-Smyth T. (1997). The biology of vascular endothelial growth factor. Endocr Rev 18: 4–25.
  • Figini M, Emanuel C, Grady EF, Kirkwood K, Payan DG, Ansel J, Gerard C, Geppetti P, Bunnett N. (1997). Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas. Am J Physiol 272:G785–G793.
  • Folkman J, D'Amore PA. (1996). Blood vessel for-mation: what is its molecular basis? Cell 87:1153–1155.
  • Fox J, Galey F, Wayland H. (1980). Action of his-tamine on the mesenteric microvasculature. Micro-vasc Res 19:108–126.
  • Fries JW, Williams AJ, Atkins RC, Newman W, Lipscomb MF, Collins T. (1993). Expression of VCA1VI-1 and E-selectin in an in vivo model of en-dothelial activation. Am J Pathol 143:725–737.
  • Gale NW, Yancopoulos GD. (1997). Ephrins and their receptors: a repulsive topic? Cell Tissue Res 290:227–241.
  • Gebb SA, Graham JA, Hanger CC, Godbey PS, Capen RL, Doerschuk CM, Wagner WW Jr. (1995). Sites of leukocyte sequestration in the pulmonary microcirculation. J Appl Physiol 79:493–497.
  • Gerritsen ME, Shen CP, McHugh MC, Atkinson WJ, Kiely JM, Milstone DS, Luscinskas FW, Girnbrone MA Jr. (1995). Activation-dependent isolation and culture of murine pulmonary microvascular endo-thelium. Microcirculation 2:151–163.
  • Gotsch U, Jager U, Dominis M, Vestweber D. (1994). Expression of P-selectin on endothelial cells is upregulated by LPS and TNF-alpha in vivo. Cell Adhes Commun 2:7–14.
  • Granger DN, Benoit JN, Suzuki M, Grisham MB. (1989). Leukocyte adherence to venular endothe-lium during ischemia-reperfusion. Am J Physiol 257:G683–G688.
  • Grega GJ, Adarnski SW. (1988). The role of venular endothelial cells in the regulation of macromolecular permeability. Microcirc Endothelium Lymphatics 4: 143–167.
  • Hartwell DW, Mayadas TN, Berger G, Frenette PS, Rayburn H, Hynes RO, Wagner DD. (1998). Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses. J Cell Biol 143:1129–1141.
  • Hellstrom M, Kal n M, Lindahl P, Abramsson A, Betsholtz C. (1999). Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel forma-tion in the mouse. Development 126:3047–3055.
  • Heltianu C, Sirnionescu M, Sirnionescu N. (1982). Histamine receptors of the microvascular endothe-lium revealed in situ with a histamine-ferritin con-jugate: characteristic high-affinity binding sites in venules. J Cell Biol 93:357–364.
  • Henninger DD, Panes J, Eppihimer M, Russell J, Gerritsen M, Anderson DC, Granger DN. (1997). Cytokine-induced VCA1VI-1 and ICAM-1 expression in different organs of the mouse. J Immunol 158: 1825–1832.
  • Hirschi KK, D'Arnore PA. (1996). Pericytes in the microvasculature. Cardiovasc Res 32:687–698.
  • Homeister JW, Zhang M, Frenette PS, Hynes RO, Wagner DD, Lowe JIB, Marks RM. (1998). Overlap-ping functions of E- and P-selectin in neutrophil recruitment during acute inflammation. Blood 92: 2345–2352.
  • Hub E, Rot A. (1998). Binding of RANTES, MCP-1, MCP-3, and MIP-1alpha to cells in human skin. Am J Pathol 152:749–757.
  • Humphrey DM, McManus LM, Hanahan DJ, Pinck-ard RN. (1984). Morphologic basis of increased vas-cular permeability induced by acetyl glyceryl ether phosphorylcholine. Lab Invest 50:16–25.
  • Johnson DW, Berg JN, Baldwin MA, Gallione CJ, Marondel I, Yoon SJ, Stenzel TT, Speer M, Pericak-Vance MA, Diamond A, Guninacher AE, Jackson CE, Attisano L, Kucherlapati R, Porteous ME, Mar-chuk DA. (1996). Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic tel-angiectasia type 2. Nat Genet 13:189–195.
  • Jones G, Hurley JV. (1984). The effect of prostacy-din on the adhesion of leucocytes to injured vascular endothelium. J Pathol 142:51–59.
  • Joris I, DeGirolami U, Wortham K, Majno G. (1982). Vascular labelling with monastral blue B. Stain Technol 57:177–183.
  • Jung U, Ley K. (1997). Regulation of E-selectin, P-selectin, and intercellular adhesion molecule 1 ex-pression in mouse cremaster muscle vasculature. Mi-crocirculation 4:311–319.
  • Kraal G, Mebius RE. (1997). High endothelial ve-nules: lymphocyte traffic control and controlled traffic. Adv Immunol 65:347–395.
  • Kubes P, Kanwar S. (1994). Histamine induces leu-kocyte rolling in post-capillary venules. A P - selectin-mediated event. J Immunol 152:3570–3577.
  • Kubes P, Suzuki M, Granger DN. (1991). Nitric ox-ide: an endogenous modulator of leukocyte adhe-sion. Proc Natl Acad Sci USA 88:4651–4655.
  • Kurose I, Wolf R, Grisham MB, Granger DN. (1995). Effects of an endogenous inhibitor of nitric oxide synthesis on postcapillary venules. Am J Phys-iol 268:H2224–H2231.
  • Langille BL. (1993). Remodeling of developing and mature arteries: endothelium, smooth muscle, and matrix. J Cardiovasc Pharmacol 21(Suppl 1):S11–S17.
  • Ley K. (1994). Histamine can induce leukocyte roll-ing in rat mesenteric venules. Am J Physiol 267:H1017–H1023.
  • Li DY, Sorensen LK, Brooke BS, Unless LD, Davis EC, Taylor DG, Boak BB, Wendel DP. (1999). De-fective angiogenesis in mice lacking endoglin. Sci-ence 284:1534–1537.
  • Lindahl P, Betsholtz C. (1998). Not all myofibro-blasts are alike: revisiting the role of PDGF-A and PDGF-B using PDGF-targeted mice. Curr Opin Nephrol Hypertens 7:21–26.
  • Lindahl P, Johansson BR, Leveen P, Betsholtz C. (1997). Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 277:242–245.
  • Maisonpierre PC, Sun i C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, McClain J, Aldrich TH, Papadopoulos N, Daly TJ, Davis S, Sato TN, Yancopoulos GD. (1997). Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277:55–60.
  • Majno G, Palade GE, Schoefl GI. (1961). Studies on inflammation II. The site of action of histamine and serotonin along the vascular tree: A topographic study. J Biophys Biochem Cytol 11:607–625.
  • Marchesi VT, Florey HW. (1960). Electron micro-scopic observations on the emigration of leukocytes. Q J Exp Physiol 45:343–348.
  • McAllister KA, Baldwin MA, Thukkani AK, Gallione CJ, Berg JN, Porteous ME, Guninacher AE, Mar-chuk DA. (1995). Six novel mutations in the endo-glin gene in hereditary hemorrhagic telangiectasia type 1 suggest a dominant-negative effect of recep-tor function. Hum Mol Genet 4:1983–1985.
  • McDonald DM. (1994). Endothelial gaps and per-meability of venules in rat tracheas exposed to in-flammatory stimuli. Am J Physiol 266:L61–L83.
  • McEver RP. (1991). Leukocyte interactions medi-ated by GMP-140. In: Cellular and Molecular Mechanisms of Inflammation (CG Cochrane and MAJ Girnbrone, Eds.) Academic Press. New York. 15–29.
  • McEver RP, Beckstead JH, Moore KL, Marshall-Carlson L, Bainton DF. (1989). GMP-140, a platelet alpha-granule membrane protein, is also synthe-sized by vascular endothelial cells and is localized in Weibel-Palade bodies. J Clin Invest 84:92–99.
  • Middleton J, Neil S, Wintle J, Clark-Lewis I, Moore H, Lam C, Auer M, Hub E, Rot A. (1997). Trans-cytosis and surface presentation of IL-8 by venular endothelial cells. Cell 91:385–395.
  • Munro JM, Pober JS, Cotran RS. (1989). Tumor necrosis factor and interferon-gamma induce dis-tinct patterns of endothelial activation and associ-ated leukocyte accumulation in skin of Papio anubis. Am J Pathol 135:121–133.
  • Murphy TJ, Thurston G, Ezaki T, McDonald DM. (1999). Endothelial cell heterogeneity in venules of mouse airways induced by polarized inflammatory stimulus. Am J Pathol 155:93–103.
  • Nagata H, Guth PH. (1984). Effect of topical his-tamine on mucosal microvascular permeability and acid secretion in the rat stomach. Am J Physiol 246:G654–G659.
  • Nehls V, Drenckhahn D. (1991). Heterogeneity of microvascular pericytes for smooth muscle type al-pha-actin. J Cell Biol 113:147–154.
  • Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. (1999). Vascular endothelial growth factor (VEGF) and its receptors. FASER J 13:9–22.
  • Nolte D, Schmid P, Jager U, Botzlar A, Roesken F, Hecht R, Uhl E, Messmer K, Vestweber D. (1994). Leukocyte rolling in venules of striated muscle and skin is mediated by P-selectin, not by L-selectin. Am J Physiol 267:H1637–H1642.
  • Northover AM. (1978). A morphological study of the effects of 5-hydroxytryptamine and indometha-cin on rat mesenteric venules. Br J Exp Pathol 59: 401–410.
  • O'Brien KD, McDonald TO, Chait A, Allen MD, Al-pers CE. (1996). Neovascular expression of E - selectin, intercellular adhesion molecule-1, and vas-cular cell adhesion molecule-1 in human atheroscle-rosis and their relation to intimal leukocyte content. Circulation 93:672–682.
  • O'Leary DD, Wilkinson DG. (1999). Eph receptors and ephrins in neural development. Curr Opin Neu-robiol 9:65–73.
  • Oshirna M, Oshirna H, Taketo MM. (1996). TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev Biol 179:297–302.
  • Pan J, McEver RP. (1995). Regulation of the human P-selectin promoter by Bc1-3 and specific homodi-meric members of the NF-kappa B/Rel family. J Biol Chem 270:23077–23083.
  • Pan J, Xia L, McEver RP. (1998). Comparison of promoters for the murine and human P-selectin genes suggests species-specific and conserved mechanisms for transcriptional regulation in endo-thelial cells. J Biol Chem 273:10058–10067.
  • Pillai AG, Awadhiya RP, Vegad JL. (1987). A topo-graphical study of increased vascular permeability in passive cutaneous anaphylaxis in the chicken. Vet Res Commun 11:221–226.
  • Pober J, Cotran RS. (1991). What can be learned from the expression of endothelial adhesion mol-ecules in tissues? Lab Invest 64:301–305.
  • Price RJ, Owens GK, Skalak TC. (1994). Irnrnuno-histochemical identification of arteriolar develop-ment using markers of smooth muscle differentia-tion. Evidence that capillary arterialization proceeds from terminal arterioles. Circ Res 75:520–527.
  • Price RJ, Skalak TC. (1996). Chronic alpha 1-ad-renergic blockade stimulates terminal and arcade arteriolar development. Am J Physiol 271:H752–H759.
  • Pries AR, Secomb TW, Gaehtgens P. (1995). Struc-ture and hemodynarnics of microvascular networks: heterogeneity and correlations. Am J Physiol 269:H1713–H1722.
  • Pries AR, Secomb TW, Gaehtgens P. (1998). Struc-tural adaptation and stability of microvascular net-works: theory and simulations. Am J Physiol 275:H349–H360.
  • Rhodin JA. (1968). Ultrastructure of mammalian venous capillaries, venules, and small collecting veins. J Ultrastruct Res 25:452–500.
  • Roberts WG, Palade GE. (1995). Increased micro-vascular permeability and endothelial fenestration induced by vascular endothelial growth factor. J Cell Sci 108:2369–2379.
  • Rosen SD, Hwang ST, Giblin PA, Singer MS. (1997). High-endothelial-venule ligands for L - selectin: identification and functions. Biochem Soc Trans 25:428–433.
  • Rot A, Hub E, Middleton J, Pons F, Rabeck C, Thierer K, Wintle J, Wolff B, Zsak M, Dukor P. (1996). Some aspects of IL-8 pathophysiology. III: Chemokine interaction with endothelial cells. J Leu-kocyte Biol 59:39–44.
  • Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, Gendron-Maguire M, Gridley T, Wolburg H, Risau W, Qin Y. (1995). Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376:70–74.
  • Sato Y, Rifkin DB. (1989). Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture. J Cell Biol 109:309–315.
  • Schlaeger TM, Bartunkova S, Lawitts JA, Teich-mann G, Risau W, Deutsch U, Sato TN. (1997). Uniform vascular-endothelial-cell-specific gene ex-pression in both embryonic and adult transgenic mice. Proc Natl Acad Sci USA 94:3058–3063.
  • Schuschke DA, Reed MW, Wingren UF, Miller FN. (1989). The rat urinary bladder: vasoactivity and macromolecular leakage in a new model. Microvasc Res 38:23–35.
  • Senis YA, Richardson M, Tinlin S, Maurice DH, Giles AR. (1996). Changes in the pattern of distri-bution of von Willebrand factor in rat aortic endo-thelial cells following thrombin generation in vivo. Br J Haematol 93:195–203.
  • Shepro D, Morel NM. (1993). Pericyte physiology. FASER J 7:1031–1038.
  • Sirnionescu N, Sirnionescu M, Palade GE. (1978). Open junctions in the endothelium of the postcapil-lary venules of the diaphragm. J Cell Biol 79:27–44.
  • Sims BE. (1991). Recent advances in pericyte biol-ogy-implications for health and disease. Can J Cardiol 7:431–443.
  • Skalak TC, Price RJ. (1996). The role of mechanical stresses in microvascular remodeling. Microcircula-tion 3:143–165.
  • Skalak TC, Price RJ, Zeller PJ. (1998). Where do new arterioles come from? Mechanical forces and microvessel adaptation. Microcirculation 5:91–94.
  • Sporn LA, Marder VJ, Wagner DD. (1986). Induc-ible secretion of large, biologically potent von Wil-lebrand factor multirners. Cell 46:185–190.
  • Sporn LA, Marder VJ, Wagner DD. (1987). von Willebrand factor released from Weibel-Palade bod-ies binds more avidly to extracellular matrix than that secreted constitutively. Blood 69:1531–1534.
  • Sporn LA, Marder VJ, Wagner DD. (1989). Differ-ing polarity of the constitutive and regulated secre-tory pathways for von Willebrand factor in endothe-lial cells. J Cell Biol 108:1283–1289.
  • Sun i C, Jones PF, Patan S, Bartunkova S, Maison-pierre PC, Davis S, Sato TN, Yancopoulos GD. (1996). Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87:1171–1180.
  • Sun i C, McClain J, Thurston G, McDonald DM, Zhou H, Oldmixon EH, Sato TN, Yancopoulos GD. (1998). Increased vascularization in mice overex-pressing angiopoietin-1. Science 282:468–471.
  • Svensjo E, Joyner WL. (1984). The effects of inter-mittent and continuous stimulation of microvessels in the cheek pouch of hamsters with histamine and bradykinin on the development of venular leaky sites. Microcirc Endothelium Lymphatics 1:381–396.
  • Thurston G, Baluk P, Hirata A, McDonald DM. (1996). Permeability-related changes revealed at endothelial cell borders in inflamed venules by lectin binding. Am J Physiol 271:H2547–H2562.
  • Thurston G, McDonald DM. (1997). Distinct glyco-conjugates on endothelial cells in postcapillary ve-nules. Microcirculation 4:A299 (Abstr).
  • Thurston G, Murphy TJ, Baluk P, Lindsey JR, Mc-Donald DM. (1998). Angiogenesis in mice with chronic airway inflammation: strain-dependent dif-ferences. Am J Pathol 153:1099–1112.
  • Thurston G, Sun i C, Smith K, McClain J, Sato TN, Yancopoulos GD, McDonald DM. (1999). Leakage-resistant blood vessels in mice transgenically over-expressing angiopoietin-2. Science (in press).
  • Thurston G, Sun i C, Smith KM, Yancopoulos GD, McDonald DM. (1999). Skin microvasculature in mice that transgenically overexpress angiopoietin-1 is resistant to inflammatory stimuli. FASEB J 13:A46 (Abstr).
  • Tsai FIVI, Nagel RL, Hatcher VB, Seaton AC, Suss-man II. (1991). The high molecular weight form of endothelial cell von Willebrand factor is released by the regulated pathway. Br J Haematol 79:239–245.
  • Valenzuela DM, Griffiths JA, Rojas J, Aldrich TH, Jones PF, Zhou H, McClain J, Copeland NG, Gilbert DJ, Jenkins NA, Huang T, Papadopoulos N, Maison-pierre PC, Davis S, Yancopoulos GD. (1999). An-giopoietins 3 and 4: diverging gene counterparts in mice and humans. Proc Natl Acad Sci USA 96: 1904–1909.
  • Vikkula M, Boon LM, Carraway KLr, Calvert JT, Diamond AJ, Gournnerov B, Pasyk KA, Marchuk DA, Warman ML, Cantley LC, Mulliken JB, Olsen BR. (1996). Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine ki-nase TIE2. Cell 87:1181–1190.
  • von Andrian UH. (1996). Intravital microscopy of the peripheral lymph node microcirculation in mice. Microcirculation 3:287–300.
  • Wagner DD, Bonfanti R. (1991). von Willebrand factor and the endothelium. Mayo Clin Proc 66: 621–627.
  • Wagner DD, Olmsted JIB, Marder VJ. (1982). Irn-munolocalization of von Willebrand protein in Wei-bel-Palade bodies of human endothelial cells. J Cell Biol 95:355–360.
  • Walton T, Wang JL, Ribas A, Barsky SH, Economou J, Nguyen M. (1998). Endothelium-specific expres-sion of an E-selectin promoter recombinant adeno-viral vector. Anticancer Res 18:1357–1360.
  • Wang HU, Chen ZF, Anderson DJ. (1998). Molecu-lar distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93:741–753.
  • Wong J, Johnston B, Lee SS, Bullard DC, Smith CW, Beaudet AL, Kubes P. (1997). A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature. J Clin Invest 99: 2782–2790.
  • Wu NZ, Baldwin AL. (1992). Transient venular permeability increase and endothelial gap formation induced by histamine. Am J Physiol 262:H1238—H1247.
  • Yancopoulos GD, Klagsbrun M, Folkman J. (1998). Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the border. Cell 93:661–664.
  • Yi ES, Ulich TR. (1992). Endotoxin, interleukin-1, and tumor necrosis factor cause neutrophil-depen-dent microvascular leakage in postcapillary venules. Am J Pathol 140:659–663.
  • Zweifach BW. (1974). Quantitative studies of mi-crocirculatory structure and function. I. Analysis of pressure distribution in the terminal vascular bed in cat mesentery. Circ Res 34:843–857.

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