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Artificial Cells, Blood Substitutes, and Biotechnology Volume 30, 2002 - Issue 2
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Original

THE EFFECTS OF HEMODILUTION WITH HEMOLINK™ UPON HEMODYNAMICS AND BLOOD FLOW DISTRIBUTION IN ANESTHETIZED DOGS *

J. G. Kingma Jr. Department of Medicine, Faculty of Medicine, Laval University, Quebec, QC, G1K 7P4, Canada
,
Reena Sandhu Hemosol Inc., 2585 Meadowpine Blvd.ON, L5N 8H9, Canada
,
N. D. Hamelin ITR Laboratories Canada Inc., 19601 Clark Graham, Baie d'Urfe, QC, H9X 3T1, Canada
,
D. Gendron ITR Laboratories Canada Inc., 19601 Clark Graham, Baie d'Urfe, QC, H9X 3T1, Canada
,
Y. Trudel ITR Laboratories Canada Inc., 19601 Clark Graham, Baie d'Urfe, QC, H9X 3T1, Canada
,
M. Bosa ITR Laboratories Canada Inc., 19601 Clark Graham, Baie d'Urfe, QC, H9X 3T1, Canada
,
R. Stewart ITR Laboratories Canada Inc., 19601 Clark Graham, Baie d'Urfe, QC, H9X 3T1, Canada
,
M. B. Fargey ITR Laboratories Canada Inc., 19601 Clark Graham, Baie d'Urfe, QC, H9X 3T1, Canada
&
G. P. Biro Hemosol Inc., 2585 Meadowpine Blvd.ON, L5N 8H9, Canada
 show all
Pages 137-154 | Published online: 11 Jul 2009

REFERENCES

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  • Adamson J. G., Moore C. Hemolink, an o-raffinose Crosslinked Hemoglobin-Based Oxygen Carrier. Blood Substitutes: Principles, Methods, Products and Clinical Trials, T.M. S. Chang. Karger Landes Systems, Basel, Switzerland 1998; Vol. II
  • Baer R. W., Payne B. D., Verrier E. D., Vlahakes G. J., Molodowitch D., Uhlig P. N., Hoffman J. I. Increased number of myocardial blood flow measurements with radionuclide-labeled microspheres. Am. J. Phys. 1984; 246: H418–H434
  • Doss D. N., Estafanous F. G., Ferrario C. M., Brum J. M., Murray P. A. Mechanism of systemic vasodilation during normovolemic hemodilution. Anesth. Analg. 1995; 81: 30–34
  • Habler O., Kleen M., Hutter J., Podtschaske A., Tiede M., Kemming G., Corso C., Batra S., Keipert P., Faithfull S., Messmer K. Effects of hemodilution on splanchnic perfusion and hepatorenal function. II. Renal perfusion and hepatorenal function. Eur. J. of Med. Res. 1997; 2: 419–424
  • Tu Y. K., Liu H. M. Effects of isovolemic hemodilution on hemodynamics, cerebral perfusion, and cerebral vascular reactivity. Stroke 1996; 27: 441–445
  • Caron A., Menu P., Faivre-Fiorina B., Labrude P., Alayash A. I., Vigneron C. Cardiovascular and hemorheological effects of three modified human hemoglobin solutions in hemodiluted rabbits. J. Appl. Physiol. 1999; 86: 541–548
  • Caron A., Menu P., Faivre-Fiorina B., Labrude P., Alayash A., Vigneron C. Systemic and renal hemodynamics after moderate hemodilution with HbOCs in anesthetized rabbits. Am. J. Physiol.: Heart Circ. Physiol. 2000; 278: H1974–H1983
  • Kleen M., Habler O., Hutter J., Podtschaske A., Tiede M., Kemming G., Corso C., Batra S., Keipert P., Faithfull S., Messmer K. Effects of hemodilution on splanchnic perfusion and hepatorenal function. I. Splanchnic perfusion. Eur. J. of Med. Res. 1997; 2: 413–418

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