Physical Properties and Stability Mechanisms of Poly(Ethylene Glycol) Conjugated Liposome Encapsulated Hemoglobin Dispersions

REFERENCES

• Jung, H.T., Coldren, B., Zasadzinski, J.A., Iampietro, D.J., Kaler, E.W. (2001). The origins of stability of spontaneous vesicles. Proc. Natl. Acad. Sci. USA 98: 1353–1357. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Stowell, C.P. (2002). Hemoglobin-based oxygen carriers. Curr. Opin. Hematol. 9: 537–543. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Riess, J.G. (2001). Oxygen carriers (“blood substitutes”)-raison d'etre, chemistry and some physiology. Chem. Rev. 101: 2797–2919. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Fournier, R.L. (1999). In Basic Transport Phenomena in Biomedical Engineering, Taylor & Francis: Philadelphia.
   Google Scholar
• Winslow, R.M. (1999). New transfusion strategies: Red cell substitutes. Annu. Rev. Med. 50: 337–353. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Teramura, Y., Kanazawa, H., Sakai, H., Takeoka, S., Tsuchida, E. (2003). Prolonged oxygen-carrying ability of hemoglobin vesicles by coencapsulation of catalase in vivo. Bioconjugate Chem. 14: 1171–1176. [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rudolph, A.S. (1994). Encapsulated hemoglobin: Current issues and future goals. Art. Cells, Blood Subs., and Immob. Biotech. 22: 347–360. [CSA]
   PubMed Web of Science ®Google Scholar
• Farmer, M.C., Gaber, B.P. (1987). Liposome-encapsulated hemoglobin as an artificial oxygen-carrying system. Methods Enzymol. 149: 184–200. [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Rudolph, A.S., Klipper, R.W., Goins, B.A., Phillips, W.T. (1991). In vivo biodistribution of a radiolabeled blood substitute: 99 m Tc-labeled liposome-encapsulated hemoglobin in an anesthetized rabbit. Proc. Natl. Acad. Sci. USA 88: 10976–10980. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Sakai, H., Tomiyama, K., Sou, K., Takeoka, S., Tsuchida, E. (2000). Poly(ethylene glycol)-conjugation and deoxygenation enable long-term preservation of hemoglobin-vesicles as oxygen carriers in a liquid state. Bioconjugate Chem. 11: 425–432. [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Szebeni, J., Alving, C.R. (1999). Complement-mediated acute effects of liposome-encapsulated hemoglobin. Art. Cells, Blood Subs., and Immob. Biotech. 27: 23–41. [CSA]
   PubMed Web of Science ®Google Scholar
• Juliano, R.L., Stamp, D. (1975). The effect of particle size and charge on the clearance rates of liposomes and liposome encapsulated drugs. Biochem. Biophys. Res. Commun. 63: 651–658. [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Goins, B., Ligler, F.S., Rudolph, A.S. (1994). Inclusion of ganglioside GM1 into liposome encapsulated hemoglobin does not extend circulation persistence at clinically relevant doses. Art. Cells, Blood Subs., and Immob. Biotech. 22: 9–25.
   PubMed Web of Science ®Google Scholar
• Bhadra, D., Bhadra, S., Jain, P., Jain, N.K. (2002). Pegnology: A review of PEG-ylated systems. Pharmazie. 57: 5–29. [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Torchilin, V.P., Papisov, M.I. (1994). Why do polyethylene glycol-coated liposomes circulate so long? Liposome Res. 4: 725–739.
   Google Scholar
• Awasthi, V.D., Garcia, D., Goins, B.A., Phillips, W.T. (2003). Circulation and biodistribution profiles of long-circulating PEG-liposomes of various sizes in rabbits. Int. J. Pharm. 253: 121–132. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Zheng, S., Zheng, Y., Beissinger, R.L., Martin, F.J. (1994). Efficacy, physical properties and pharmacokinetics of sterically-stabilized liposomes-encapsulated hemoglobin. Art. Cells, Blood Subs., and Immob. Biotech. 22: 487–501.
   PubMed Web of Science ®Google Scholar
• Phillips, W.T., Klipper, R.W., Awasthi, V.D., Rudolph, A.S., Cliff, R., Kwasiborski, V., Goins, B.A. (1998). Polyethylene glycol-modified liposome-encapsulated hemoglobin: a long circulating red cell substitute. J. Pharmacol. Exp. Ther. 288: 665–670. [CSA]
   Google Scholar
• Sakai, H., Takeoka, S., Park, S.I., Kose, T., Nishide, H., Izumi, Y., Yoshizu, A., Kobayashi, K., Tsuchida, E. (1997). Surface modification of hemoglobin vesicles with poly(ethylene glycol) and effects on aggregation, viscosity and blood flow during 90% exchange transfusion in anesthesized rats. Bioconjugate Chem. 8: 23–30. [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wakamoto, S., Fujihara, M., Abe, H., Sakai, H., Takeoka, S., Tsuchida, E., Ikeda, H., Ikebuchi, K. (2001). Effects of poly(ethylenelglycol)-modified hemoglobin vesicles on agonist-induced platelet aggregation and RANTES release in vitro. Art. Cells, Blood Subs., and Immob. Biotech. 29: 191–201. [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sherwood, R.L., McCormick, D., Zheng, S., Beissinger, R.L. (1995). Influence of steric sabilization of liposome-encapsulated hemoglobin on listeria monocytogenes host defense. Art. Cells, Blood Subs., and Immob. Biotech. 23: 665–679. [CSA]
   PubMed Web of Science ®Google Scholar
• Nakai, K., Usuba, A., Ohta, T., Kuwabara, M., Nakazato, Y., Motoki, R., Takahashi, T.A. (1998). Coronary vascular bed perfusion with a polyethylene glycol-modified hemoglobin-encapsulated liposome, neo red cell, in rats. Art. Organs. 22: 320–325. [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sakai, H., Tsai, A.G., H.K. Park, S.I., Takeoka, S., Nishide, H., Tsuchida, E., Intaglietta, M. (1997). Subcutaneous microvascular responses to hemodilution with a red cell substitute consisting of polyethyleneglycol-modified vesicles encapsulating hemoglobin. J. Biomed. Mater. Res. 40: 66–78. [CSA], [CROSSREF]
   Google Scholar
• Takahashi, A. (1995). Characterization of neo red-cells (NRCs), their function and safety in-vivo tests. Art. Cells, Blood Subs., and Immob. Biotech. 23: 347–354. [CSA]
   PubMed Web of Science ®Google Scholar
• Utkhede, D.R., Tilcock, C.P. (1998). Studies upon the toxicity of polyethylene glycol coated lipid vesicles: acute hemodynamic effects, pyrogenicity and complement activation. J. Liposome Res. 8: 537–550. [CSA]
   Web of Science ®Google Scholar
• Arifin, D.R., Palmer, A.F. (2003). Determination of size distribution and encapsulation efficiencies of liposomes encapsulated hemoglobin by asymmetric flow field-flow fractionation and multi-angle light scattering. Biotech. Prog. 19: 1798–1811. [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wright, R.O., Magnani, B., Shannon, M.W., Woolf, A.D. (1996). N-acetylcysteine reduces methemoglobin in vitro. Ann. of Emergency Med. 28: 499–503. [CSA]
   PubMed Web of Science ®Google Scholar
• Wallace, W.J., Maxwell, J.C., Caughey, W.S. (1974). A role for chloride in the autoxidation of hemoglobin under conditions similar to those in erythrocytes. FEBS Lett. 43: 33–36. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMedGoogle Scholar
• Jung, H.T., Lee, S.Y., Kaler, E.W., Coldren, B., Zasadzinski, J.A. (2002). Gausssian curvature and the equilibrium among bilayer cylinders, spheres, and discs. Proc. Natl. Acad. Sci. USA 99: 15318–15322. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Kang, S.Y., Seong, B.S., Han, Y.S., Jung, H.T. (2002). Self-organization of amphiphilic polymer in vesicle bilayers composed of surfactant mixtures. Biomacromolecules 4: 360–365. [CSA], [CROSSREF]
   Google Scholar
• Rawicz, W., Olbrich, K.C., McIntosh, T., Needham, D., Evans, E. (2000). Effect of chain length and unsaturation on elasticity of lipid bilayers. Biophys. J. 79: 328–339. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Arifin, D.R., Palmer, A.F. (2005). Stability of liposome encapsulated hemoglobin dispersions. Art. Cells, Blood Subs., and Biotech. 33((2)): 113–136. [CSA]
   PubMedGoogle Scholar
• Eike, J.H., Palmer, A.F. (2005). The effect of NaBH4 concentration and reaction time on the physical properties of glutaraldehyde polymerized hemoglobin. Biotech. Prog. 20: 946–952. [CSA], [CROSSREF]
   Google Scholar
• Eike, J.H., Palmer, A.F. (2004). Effect of glutaraldehyde concentration on physical properties of polymerized hemoglobin. Biotech. Prog. 20: 1225–1232. [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Eike, J.H., Palmer, A.F. (2004). Effect of Cl− and H+ on the oxygen binding properties of gluteraldehyde-polymerized bovine hemoglobin-based blood substitutes. Biotech. Prog. 20: 1543–1549.
   PubMed Web of Science ®Google Scholar
• Eike, J.H., Palmer, A.F. (2004). Oxidized mono-, di-, tri-, and polysaccharides as potential hemoglobin cross-linking reagents for the synthesis of high oxygen affinity artificial blood substitutes. Biotech. Prog. 20: 953–962. [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sakai, H., Masada, Y., Takeoka, S., Tsuchida, E. (2002). Characteristics of bovine hemoglobin as a potential source of hemoglobin-vesicles for an artificial oxygen carrier. J. Biochem. 131: 611–617. [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Bruckdorfer, K.R., Demel, R.A., DeGier, J., Van Deenen, L.L.M. (1969). The effect of partial replacements of membrane cholesterol by other steroids on the osmotic fragility and glycerol permeability of erythrocytes. Biochem. Biophys. Acta. 183: 334–345. [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Papahadjopoulos, D., Poste, G., Schaeffer, B.E., Vail, W.J. (1974). Membrane fusion and molecular segregation in phospholipid vesicles. Biochem. Biophys. Acta. 352: 10–28. [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Papahadjopoulos, D., Kimelberg, H.K. (1973). Phospholipid vesicles (liposomes) as models for biological membranes: their properties and interactions with cholesterol and proteins. Prog. Surf. Sci. 4: 141–144. [CROSSREF]
   Google Scholar
• Korgel, B.A., VanZanten, J.H., Monbouquette, H.G. (1998). Vesicle size distributions measured by flow field-flow fractionation coupled with multiangle light scattering. Biophys. J. 74: 3264–3272. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Li, S.L., Palmer, A.F. (2004). Structure of small actin-containing liposomes probed by atomic force microscopy: Effect of actin concentration and liposome size. Langmuir. 20: 7917–7925. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMedGoogle Scholar
• Li, S.L., Palmer, A.F. (2004). Effect of actin concentration on the structure of actin-containing liposomes. Langmuir. 20: 4629–4639. [CROSSREF]
   PubMedGoogle Scholar
• Li, S.L., Nickels, J., Palmer, A.F. (2005). Liposome-encapsulated actin-hemoglobin (LEAcHb) artificial blood substitutes. Biomaterials. 26: 3759–3769. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Patton, J.N., Palmer, A.F. (2005). Photopolymerization of bovine hemoglobin entrapped nanoscale hydrogel particles within liposomal reactors for use as an artificial blood substitute. Biomacromolecules. 6: 414–424. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Nickels, J., Palmer, A.F. (2003). Changes in liposomes morphology induced by actin polymerization in submicrometer liposomes. Langmuir. 19: 10581–10587. [CROSSREF]
   Google Scholar
• Palmer, A.F., Wingert, P., Nickels, J. (2003). Atomic force microscopy and light scattering of small unilamellar actin-containing liposomes. Biophys. J. 85: 1233–1247. [PUBMED], [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Voet, D., Voet, J.G. (1995). In Biochemistry, John Wiley & Sons, Inc.: New York, 241–242.
   Google Scholar
• Denkov, N.D., Yoshimura, H., Kouyama, T., Walz, J., Nagayama, K. (1998). Electron cryomicroscopy of bacteriorhodopsin vesicles: mechanism of vesicle formation. Biophys. J. 74: 1409–1420. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Israelachvili, J. (1995). In Intermolecular & Surface Forces, Academic Press Inc.: San Diego.
   Google Scholar
• Helfrich, W. (1973). Elastic properties of lipid bilayers: theory and possible experiments. Z. Naturforsch. 28: 693–703.
   Google Scholar
• Awasthi, V.D. (2003). ( personal communication).
   Google Scholar
• Winslow, R.M. (2003). Current status of blood substitute research: Towards a new paradigm. J. Intern. Med. 253: 508–517. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lasic, D.D., Joannic, R., Keller, B.C., Frederik, P.M., Auvray, L. (2001). Spontaneous vesiculation. Adv. Colloid Interface Sci. 89–90: 337–349. [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Gradzielski, M. (2003). Vesicles and vesicle gels-structure and dynamics of formation. J. Phys.: Condens. Matter 15: R655–R697.
   Web of Science ®Google Scholar
• Lasic, D.D. (1998). Novel applications of liposomes. Reviews 16: 307–321.
   Google Scholar
• Marsh, D. (2001). Elastic constants of polymer-grafted lipid membranes. Biophys. J. 81: 2154–2162. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Szebeni, J., Hauser, H., Eskelson, C.D., Watson, R.R., Winterhalter, K.H. (1988). Interaction of hemoglobin derivatives with liposomes. Membrane cholesterol protects against the changes of hemoglobin. Biochemistry 27: 6425–6434. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Marsh, D., Bartucci, R., Sportelli, L. (2003). Lipid membranes with grafted polymers: physicochemical aspects. Biochim. Biophys. Acta. 1615: 33–59. [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Sakai, H., Hamada, K., Takeoka, S., Nishide, H., Tsuchida, E. (1996). Physical propeties of hemoglobin vesicles as red cell substitutes. Biotechnol. Prog. 12: 119–125. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar