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Research Article

Marine Antivenoms

ANTIVENOMS

Pages 301-308 | Published online: 05 Dec 2003

References

  • Handbook of clinical toxicology of animal venoms and poisons, J Meier, J White. CRC Press, Inc, Florida 1995
  • Venomous & poisonous marine animals, JA Williamson, PJ Fenner, JW Burnett, JF Rifkin. University of New South Wales Press, Sydney 1996
  • Currie BJ. Clinical toxicology: a tropical Australian perspective. Ther Drug Monit 2000; 22(1)73–78
  • O'Reilly GM, Isbister GK, Lawrie PM, Treston GT, Currie BJ. Prospective study of jellyfish stings from tropical Australia, including the major box jellyfish Chironex fleckeri. Med J Aust 2001; 175: 652–655
  • Lumley J, Williamson JA, Fenner PJ, Burnett JW, Colquhoun DM. Fatal envenomation by Chironex fleckeri, the north Australian box jellyfish: the continuing search for lethal mechanisms. Med J Aust 1988; 148(10)527–534
  • Currie B. Clinical implications of research on the box-jellyfish Chironex fleckeri. Toxicon 1994; 32(11)1305–1313
  • Othman I, Burnett JW. Techniques applicable for purifying Chironex fleckeri (box-jellyfish) venom. Toxicon 1990; 28(7)821–835
  • Baxter EH, Marr AG. Sea wasp (Chironex fleckeri) venom: lethal, haemolytic and dermonecrotic properties. Toxicon 1969; 7(3)195–210
  • Freeman SE, Turner RJ. A pharmacological study of the toxin in a Cnidarian Chironex fleckeri Southcott. Br J Pharmacol 1969; 35(3)510–520
  • Keen TE. Recent investigations on sea-wasp stingings in Australia. Med J Aust 1970; 1(6)266–270
  • Keen TE, Crone HD. Dermatonecrotic properties of extracts from the tentacles of the cnidarian Chironex fleckeri. Toxicon 1969; 7(3)173–180
  • Burnett JW, Calton GJ. The chemistry and toxicology of some venomous pelagic coelenterates. Toxicon 1977; 15(3)177–196
  • Williamson JA, Le Ray LE, Wohlfahrt M, Fenner PJ. Acute management of serious envenomation by box-jellyfish (Chironex fleckeri). Med J Aust 1984; 141(12–13)851–853
  • Czarnetzki BM, Thiele T, Rosenbach T. Evidence for leukotrienes in animal venoms. J Allergy Clin Immunol 1990; 85(2)505–509
  • Endean R, Duchemin C, McColm D, Fraser EH. A study of the biological activity of toxic material derived from nematocysts of the cubomedusan Chironex fleckeri. Toxicon 1969; 6(3)179–204
  • Freeman SE, Turner RJ. Cardiovascular effects of toxins isolated from the cnidarian Chironex fleckeri Southcott. Br J Pharmacol 1971; 41(1)154–166
  • Mustafa MR, White E, Hongo K, Othman I, Orchard CH. The mechanism underlying the cardiotoxic effect of the toxin from the jellyfish Chironex fleckeri. Toxicol Appl Pharmacol 1995; 133(2)196–206
  • Endean R, Monks SA, Cameron AM. Toxins from the box-jellyfish Chironex fleckeri. Toxicon 1993; 31(4)397–410
  • Endean R. Separation of two myotoxins from nematocysts of the box jellyfish (Chironex fleckeri). Toxicon 1987; 25(5)483–492
  • Sutherland SK, Tibballs J. Australian animal toxins. The creatures, their toxins and care of the poisoned patient. 2nd ed, OUP, Melbourne 2001
  • Baxter EH, Marr A. Seawasp (Chironex fleckeri) antivenene: neutralizing potency against the venom of three other jellyfish species. Toxicon 1974; 12: 223–229
  • Burnett JW, Othman IB, Endean R, Fenner PJ, Callanan VI, Williamson JA. Verapamil potentiation of Chironex (box-jellyfish) antivenom. Toxicon 1990; 28(2)242–244
  • Endean R, Sizemore DJ. The effectiveness of antivenom in countering the actions of box-jellyfish (Chironex fleckeri) nematocyst toxins in mice. Toxicon 1988; 26(5)425–431
  • White J. CSL antivenom handbook. CSL Ltd, Melbourne 1995
  • Williamson JA, Callanan VI, Hartwick RF. Serious envenomation by the Northern Australian box-jellyfish (Chironex fleckeri). Med J Aust 1980; 1(1)13–16
  • Beadnell CE, Rider TA, Williamson JA, Fenner PJ. Management of a major box jellyfish (Chironex fleckeri) sting. Lessons from the first minutes and hours. Med J Aust 1992; 156(9)655–658
  • Maguire EJ. Chironex fleckeri (“sea wasp”) sting. Med J Aust 1968; 2(25)1137–1138
  • Tibballs J, Williams D, Sutherland SK. The effects of antivenom and verapamil on the haemodynamic actions of Chironex fleckeri (box jellyfish) venom. Anaesth Intensive Care 1998; 26(1)40–45
  • Fenner PJ, Williamson JA, Blenkin JA. Successful use of Chironex antivenom by members of the Queensland Ambulance Transport Brigade. Med J Aust 1989; 151(11–12)708–710
  • Riviere G, Choumet V, Audebert F, et al. Effect of antivenom on venom pharmacokinetics in experimentally envenomed rabbits: toward an optimization of antivenom therapy. J Pharmacol Exp Ther 1997; 281(1)1–8
  • Keen TEB. Comparison of tentacle extracts from Chiropsalmus quadrigatus and Chironex fleckeri. Toxicon 1971; 9: 249–254
  • Fenner PJ, Rodgers D, Williamson J. Box jellyfish antivenom and “Irukandji” stings. Med J Aust 1986; 144: 665–666
  • Wiener S. Observations on the venom of the Stonefish (Synanceja trachynis). Med J Aust 1959; 1: 620–627
  • Kreger AS. Detection of a cytolytic toxin in the venom of the stonefish (Synanceia trachynis). Toxicon 1991; 29(6)733–743
  • Khoo HE, Yuen R, Poh CH, Tan CH. Biological activities of Synanceja horrida (stonefish) venom. Nat Toxins 1992; 1(1)54–60
  • Hopkins BJ, Hodgson WC, Sutherland SK. Pharmacological studies of stonefish (Synanceja trachynis) venom. Toxicon 1994; 32(10)1197–1210
  • Hopkins BJ, Hodgson WC. Enzyme and biochemical studies of stonefish (Synanceja trachynis) and soldierfish (Gymnapistes marmoratus) venoms. Toxicon 1998; 36(5)791–793
  • Colasante C, Meunier FA, Kreger AS, Molgo J. Selective depletion of clear synaptic vesicles and enhanced quantal transmitter release at frog motor nerve endings produced by trachynilysin, a protein toxin isolated from stonefish (Synanceia trachynis) venom. Eur J Neurosci 1996; 8(10)2149–2156
  • Sauviat MP, Meunier FA, Kreger A, Molgo J. Effects of trachynilysin, a protein isolated from stonefish (Synanceia trachynis) venom, on frog atrial heart muscle. Toxicon 2000; 38(7)945–959
  • Church JE, Hodgson WC. Dose-dependent cardiovascular and neuromuscular effects of stonefish (Synanceja trachynis) venom. Toxicon 2000; 38(3)391–407
  • Poh CH, Yuen R, Khoo HE, Chung M, Gwee M, Gopalakrishnakone P. Purification and partial characterization of stonustoxin (lethal factor) from Synanceja horrida venom. Comp Biochem Physiol B 1991; 99(4)793–798
  • Low KS, Gwee MC, Yuen R, Gopalakrishnakone P, Khoo HE. Stonustoxin: a highly potent endothelium-dependent vasorelaxant in the rat. Toxicon 1993; 31(11)1471–1478
  • Garnier P, Sauviat MP, Goudey-Perriere F, Perriere C. Cardiotoxicity of verrucotoxin, a protein isolated from the venom of Synanceia verrucosa. Toxicon 1997; 35(1)47–55
  • Garnier P, Ducancel F, Ogawa T, et al. Complete amino-acid sequence of the beta-subunit of VTX from venom of the stonefish (Synanceia verrucosa) as identified from cDNA cloning experiments. Biochim Biophys Acta 1997; 1337(1)1–5
  • Wiener S. The production and assay of Stonefish antivenene. Med J Aust 1959; 2: 715–719
  • Church JE, Hodgson WC. Stonefish (Synanceia spp.) antivenom neutralises the in vitro and in vivo cardiovascular activity of soldierfish (Gymnapistes marmoratus) venom. Toxicon 2001; 39(2–3)319–324
  • Appendix: Antivenom tables. J Clin Toxicol 2003; 41(3)317–327

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