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Editorial

Doxorubicin for Metastatic Breast Cancer: Time for a Change?

, M.D.
Pages 967-968 | Published online: 12 Oct 2003

References

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  • Chao T.-C., Wang J.-C., Yen C.-C., et al. A dose-escalating pilot study of sterically stabilized pegylated liposome doxorubicin (Lipo-Dox®) in patients with metastatic breast cancer. Cancer Invest., (this issue)
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  • Wigler N., Inbar M., O'Brien R., et al. Reduced cardiac toxicity and comparable efficacy in a phase III trial of pegylated liposomal dosxorubicin (Caelyx, Doxil) vs. doxorubicin for first-line treatment of metastatic breast cancer. Proc. Am. Soc. Clin. Oncol. 2002; 21: 45a, (abstract 177)
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  • Sparano J., Malik U., Rajdev L., et al. Phase I trial of pegylated liposomal doxorubicin and docetaxel in advanced breast cancer. J. Clin. Oncol. 2001; 19: 3117–3225
  • Safra T., Muggia F., Jeffers S., et al. Pegylated liposomal doxorubicin (DOXIL): reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/m2. Ann. Oncol. 2000; 11: 1029–1033
  • Hamilton A., Biganzoli L., Coleman R., et al. EORTC 10968: a phase I clinical and pharmacokinetic study of polyethylene glycol liposomal doxorubicin (Caelyx®, Doxil®) at a 6-week interval in patients with metastatic breast cancer. Ann. Oncol. 2002; 13: 910–918

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