EFFECTS OF THE RAT HEPATIC PEROXISOME PROLIFERATOR, WYETH 14,643, ON THE LACTATING GOAT

REFERENCES

• Gibson G., Lake B. Peroxisomes: Biology and Importance in Toxicology and Medicine, G. Gibson, B. Lake. Taylor and Francis Company, Washington, D.C. 1993
   Google Scholar
• Roberts R.A. Peroxisome Proliferators: Mechanisms of Adverse Effects in Rodents and Molecular Basis for Species Differences. Arch. Toxicol. 1999; 73: 413–418
   PubMed Web of Science ®Google Scholar
• Choudhury A.I., Chahal S., Bell A.R., Tomlinson S.R., Roberts R.A., Salter A.M., ell D.R. Species Differences in Peroxisome Proliferation; Mechanisms and Relevance. Mutation Research 2000; 448: 201–212
   PubMed Web of Science ®Google Scholar
• Corton J.C., Lapinskas P.L., Gonzalez F.J. Central Role of PPARα in the Mechanism of Actions of Hepatocarcinogenic Peroxisome Proliferators. Mutat. Research 2000; 448: 139–151
   PubMed Web of Science ®Google Scholar
• Malinverno G., Rusch G.M., Millischer R.J., Hughes E.W., Schroeder R.E., Coombs D.W. Inhalation Teratology and Reproduction Studies with 1,1-dicloro-2,2,-trifluorethane (HFC-123). Fund. Appl. Toxicol. 1996; 34: 276–287
   PubMedGoogle Scholar
• Gibson J.P., Larson E.J., Yarrington J.T., Hook R.H., Kariya T., Blohm T.R. Toxicity and Teratogenicity Studies with the Hypolipidemic Drug RMI 14,514 in Rats. Fund. Appl. Toxicol. 1981; 1: 19–25
   PubMedGoogle Scholar
• Fitzgerald J.E., Petrere J.A., de la Iglesia F.A. Experimental Studies on Reproduction with Lipid-Regulating Agent Gemfibrozil. Fund. Appl. Toxicol. 1987; 8: 454–464
   PubMedGoogle Scholar
• Brandorff N.P. The Effects of Dietary Fat on the Fatty Acid Composition of Lipids Secreted in Rats’ Milk. Lipids 1980; 15: 276–278
   PubMed Web of Science ®Google Scholar
• Galli C., Spagnuolo C. Essential Fatty Acids in Maternal Diet and in Rat Milk Phospholipids. Lipids 1974; 9: 1030–1032
   PubMed Web of Science ®Google Scholar
• Mozes S., Kuchar S., Rybosova Z., Novakova V. Milk Fat Concentration and Growth Rate of Rat Pups. Physiol. Res. 1993; 42: 29–33
   PubMed Web of Science ®Google Scholar
• Haughom B., Spydevold O. The Mechanism Underlying the Hypolipemic Effect of Perfluorooctanoic Acid (PFOA), Perfluorooctane Sulphonic Acid (PFOSA) and Clofibric Acid. Biochem. Biophys.Acta 1992; 1128: 65–72
   PubMed Web of Science ®Google Scholar
• Capuzzi D.M., Lackman R.D., Alexander J., Intenzo C.M., Reed M.A. Rapid Modulation of Lipogenesis by Clofibrate in Rat and Monkey Hepatocytes. Biochem. Biophys. Acta 1975; 409: 144–155
   PubMed Web of Science ®Google Scholar
• Grigor M.R., Poczwa Z., Arthur P.G. Milk Lipid Synthesis and Secretion During Milk Stasis in the Rat. Journal of Nutrition 1986; 116: 1789–1797
   PubMed Web of Science ®Google Scholar
• Malley L.A., Carakostas M., Hansen J.F., Rusch G.M., Kelly D.P., Trochimowicz H.J. Two-year Inhalation Toxicity Study in Rats with the Hydrochlorofluorocarbon 123. Fund. Appl. Toxicol. 1995; 25: 101–114
   PubMedGoogle Scholar
• Buschmann J., Bartsch W., Dasenbrock R.F., Fuhst R., Pohlmann G., Preib A., Berger-Preib E. Cross-Fostering Inhalation Toxicity Study with HCFC-123 in Lactating Sprague-Dawley Rats. Inhal. Toxicol. 2001; 13: 671–687
   PubMed Web of Science ®Google Scholar
• Biegel L.A., Hurtt M.E., Frame S.R., Applegate M., O’Connor J.C., Cook J.C. Comparison of the Effects of Wyeth-14,643 in Crl:CD BR Rats and Fisher-344 Rats. Fund. Appl. Toxicol. 1992; 19: 590–597
   PubMedGoogle Scholar
• Belanger J.B. Milk. Raising Milk Goats the Modern Way, 6th Ed., J.B. Belanger. Garden Way Publishing. 1992; 13–22
   Google Scholar
• Biegel L.A., Hurtt M.E., Frame S.R., Cook J.C. Mechanisms of Extrahepatic Tumor Induction by Peroxisome Proliferators in Male CD Rats. Toxicol. Sci. 2001; 60: 44–55
   PubMed Web of Science ®Google Scholar
• Vernon R.G., Clegg R.A., Flint D.J. Metabolism of Sheep Adipose Tissue During Pregnancy and Lactation. Biochem. J. 1981; 200: 307–314
   PubMed Web of Science ®Google Scholar
• Liu R.C., Hurtt M.E., Cook J.C., Biegel L.A. Effect of the Peroxisome Proliferator, Ammonium Perfluorooctanoate (C8), on Hepatic Aromatase Activity in Adult Male Crl: CD BR Rats. Fund. Appl. Toxicol. 1996; 30: 220–228
   PubMedGoogle Scholar
• Palmer C.N.A., Hsu M.H., Griffin K.J., Johnson E.F. Peroxisome Proliferator Activated Receptor α Expression in Human Liver. Mol. Pharmacol. 1998; 53: 14–22
   PubMed Web of Science ®Google Scholar
• Tugwood J.D., Holden N.H., James R.A., Prince R.A., Roberts R.A. A Peroxisome Proliferator-alpha (PPAR alpha) cDNA Cloned from Guinea-Pig Liver Encodes a Protein with Similar Properties to the Mouse PPAR alpha: Implications for Species Differences in Responses to Peroxisome Proliferators. Arch. Toxicol. 1998; 72: 169–177
   PubMed Web of Science ®Google Scholar
• Sausen P.J., Teets V.J., Voss K.S., Miller R.T., Cattley R.C. Gemfibrozil-induced Peroxisome Proliferation and Hepatomegaly in Male F344 Rats. Cancer Letters 1995; 97: 263–268
   PubMed Web of Science ®Google Scholar
• Maffei-Facino R., Carini M., Tofanetti O., Casciarri I., Longoni E. Experimental Studies on Pharmacology, Metabolism and Toxicology with Tiadenol-Disulfoxide. Dissociation of Lipid-Lowering Effects and the Induction of Peroxisomal and Microsomal Drug-Metabolizing Enzymes. Arzneimittel-Forschung 1987; 37: 682–691
   PubMed Web of Science ®Google Scholar
• Moody D.E., Reddy J.K., Azarnoff D.L. Peroxisome-Associated Enzymes and Serum Lipids in Tumor-bearing Rats Treated with Peroxisome-Proliferating Agents. Biochem. Pharmacol. 1984; 33: 2591–2597
   PubMed Web of Science ®Google Scholar
• Hurtt M.E., Elliot G.S., Cook J.C., Obourn J.D., Frame S.R., Biegel L.B. Induction of Coagulation Effects by Wyeth-14,643 in Crl:CD®BR Rats. Drug Chem. Toxicol. 1997; 20: 1–10
   PubMed Web of Science ®Google Scholar