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Research Article

NMR-BASED METABOLOMICS

, Ph.D.
Pages 375-382 | Published online: 09 Mar 2002

REFERENCES

  • Nicholson J.K., Lindon J.C., Holmes E. Metabonomics: Understanding the Metabolic Responses of Living Systems to Pathophysiological Stimuli via Multivariant Statistical Analysis of Biological NMR Spectroscopic Data. Xenobiotica 1999; 29: 1181–1189
  • Lindon J.C., Nicholson J.K., Everett J.R. NMR Spectroscopy of Biofluids. Annual Reports on NMR Spectroscopy, G.A. Webb. Academic Press, New York 1999; Vol. 38: 1–88
  • Gartland K.P.R., Beddell C.R., Lindon J.C., Nicholson J.K. Application of Pattern Recognition Methods to the Analysis and Classification of Toxicological Data Derived from Proton Nuclear Magnetic Resonance Spectroscopy of Urine. Mol. Pharmacol. 1991; 39: 629–642
  • Gartland K.P.R., Sanins S.M., Nicholson J.K., Sweatman B.C., Beddell C.R., Lindon J.C. Pattern Recognition Analysis of High Resolution 1H NMR Spectra of Urine. A Nonlinear Mapping Approach to the Classification of Toxicological Data. NMR Biomed. 1990; 3: 166–172
  • Holmes E., Nicholls A.W., Lindon J.C., Spraul R.M., Neidig P., Connor S.C., Connelly J., Damment S.J.P., Haselden J., Nicholson J.K. Development of a Model for Classification of Toxin-induced Lesions using 1H NMR Spectroscopy of Urine Combined with Pattern Recognition. NMR Biomed. 1998; 11: 235–244
  • Gavaghan C.L., Holmes E., Lenz E., Wilson I.D., Nicholson J.K. An NMR-based Metabonomics Approach to Investigate the Biochemical Consequences of Genetic Strain Differences: Application to the C57BL10J and Alpk:ApfCD Mouse. FEBS Lett. 2000; 484: 169–174
  • Griffin J.L., Walker L.A., Garrod S., Holmes E., Shore R.F., Nicholson J.K. NMR Spectroscopy Based Metabonomic Studies on the Comparative Biochemistry of the Kidney and Urine of the Bank Vole (Clethrionomys glareolus), Wood Mouse (Apodemus sylvaticus), White Toothed Shrew (Crocidura suaveolens) and the Laboratory Rat. Comp. Biochem. Physiol. 2000; B127: 357–367
  • Robertson D.G., Bulera S.J. High-throughput Toxicology: Practical Considerations. Cur. Opin. Drug Disc. Develop. 2000; 3: 42–47
  • Becker E.D. High Resolution NMR: Theory and Chemical Applications, 3rd Ed. Academic Press, New York 2000; 334–339

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