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Clinical Study

Intravenous Treatment of Hyperhomocysteinemia in Patients on Chronic Hemodialysis—A Pilot Study

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Pages 703-708 | Published online: 07 Jul 2009

References

  • Mallamaci F., Zoccali C., Tripepi G., Fermo I., Benedetto F. A., Cataliotti A., Bellanuova I., Malatino L. S., Soldarini A. Hyperhomocysteinemia predicts cardiovascular outcomes in hemodialysis patients. Kidney Int. 2002; 61(2)609–614, [PUBMED], [INFOTRIEVE]
  • Moustapha A., Naso A., Nahlawi M., Gupta A., Arheart K. L., Jacobsen D. W., Robinson K., Dennis V. W. Prospective study of hyperhomocysteinemia as an adverse cardiovascular risk factor in end‐stage renal disease. Circulation 1998; 97(2)138–141, [PUBMED], [INFOTRIEVE]
  • Woodside J. V., Yarnell J. W., McMaster D., Young I. S., Harmon D. L., McCrum E. E., Patterson C. C., Gey K. F., Whitehead A. S., Evans A. Effect of B‐group vitamins and antioxidant vitamins on hyperhomocysteinemia: a double‐blind, randomized, factorial‐design, controlled trial. Am. J. Clin. Nutr. 1998; 67(5)858–866, [PUBMED], [INFOTRIEVE]
  • Bostom A. G., Culleton B. F. Hyperhomocysteinemia in chronic renal disease. J. Am. Soc. Nephrol. 1999; 10(4)891–900, [PUBMED], [INFOTRIEVE]
  • Look M. P., Riezler R., Reichel C., Brensing K. A., Rockstroh J. K., Stabler S. P., Spengler U., Berthold H. K., Sauerbruch T. Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma‐cystathionase?. Scand. J. Gastroenterol. 2000; 35(8)866–872, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • van Guldener C., Kulik W., Berger R., Dijkstra D. A., Jakobs C., Reijngoud D. J., Donker A. J., Stehouwer C. D., De Meer K. Homocysteine and methionine metabolism in ESRD: a stable isotope study. Kidney Int. 1999; 56(3)1064–1071, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Dierkes J., Domrose U., Ambrosch A., Bosselmann H. P., Neumann K. H., Luley C. Response of hyperhomocysteinemia to folic acid supplementation in patients with end‐stage renal disease. Clin. Nephrol. 1999; 51(2)108–115, [PUBMED], [INFOTRIEVE]
  • Bostom A. G., Shemin D., Lapane K. L., Hume A. L., Yoburn D., Nadeau M. R., Bendich A., Selhub J., Rosenberg I. H. High dose‐B‐vitamin treatment of hyperhomocysteinemia in dialysis patients. Kidney Int. 1996; 49(1)147–152, [PUBMED], [INFOTRIEVE]
  • Thambyrajah J., Landray M. J., McGlynn F. J., Jones H. J., Wheeler D. C., Townend J. N. Does folic acid decrease plasma homocysteine and improve endothelial function in patients with predialysis renal failure?. Circulation 2000; 102(8)871–875, [PUBMED], [INFOTRIEVE]
  • Sombolos K., Fragia T., Natse T., Bartholomatos G., Karagianni A., Katsaris G., Christidou F., Bamichas G., Stangou M., Papagalanis N. The effect of long‐term intravenous high dose B‐complex vitamins with or without folic acid on serum homocysteine in hemodialysis patients. J. Nephrol. 2002; 15(6)671–675, [PUBMED], [INFOTRIEVE]
  • Sunder‐Plassmann G., Fodinger M., Buchmayer H., Papagiannopoulos M., Wojcik J., Kletzmayr J., Enzenberger B., Janata O., Winkelmayer W. C., Paul G., Auinger M., Barnas U., Horl W. H. Effect of high dose folic acid therapy on hyperhomocysteinemia in hemodialysis patients: results of the Vienna multicenter study. J. Am. Soc. Nephrol. 2000; 11(6)1106–1116
  • Kaplan L. N., Mamer O. A., Hoffer L. Parenteral vitamin B12 reduces hyperhomocysteinemia in end‐stage renal disease. J. Clin. Invest. Med. 2001; 24(1)5–11
  • Ducloux D., Aboubakr A., Motte G., Toubin G., Fournier V., Chalopin J. M., Drueke T., Massy Z. A. Hyperhomocysteinemia therapy in hemodialysis patients: folinic versus folic acid in combination with vitamin B6 and B12. Nephrol. Dial. Transplant. 2002; 17(5)865–870, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Koyama K., Usami T., Takeuchi O., Morozumi K., Kimura G. Efficacy of methylcobalamin on lowering total homocysteine plasma concentrations in hemodialysis patients receiving high‐dose folic acid supplementation. Nephrol. Dial. Transplant. 2002; 17(5)916–922, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Touam M., Zingraff J., Jungers P., Chadefaux‐Vekemans B., Drueke T., Massy Z. A. Effective correction of hyperhomocysteinemia in hemodialysis patients by intravenous folinic acid and pyridoxine therapy. Kidney Int. 1999; 56(6)2292–2296, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Lentz S. R. Homocysteine and vascular dysfunction. Life Sci. 1997; 61(13)1205–1215, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Bostom A. G., Shemin D., Verhoef P., Nadeau M. R., Jacques P. F., Selhub J., Dworkin L., Rosenberg I. H. Elevated fasting total plasma homocysteine levels and cardiovascular disease outcomes in maintenance dialysis patients. A prospective study. Arterioscler. Thromb. Vasc. Biol. 1997; 17(11)2554–2558, [PUBMED], [INFOTRIEVE]
  • Arnadottir M., Brattstrom L., Simonsen O., Thysell H., Hultberg B., Andersson A., Nilsson‐Ehle P. The effect of high‐dose pyridoxine and folic acid supplementation on serum lipid and plasma homocysteine concentrations in dialysis patients. Clin. Nephrol. 1993; 40(4)236–240, [PUBMED], [INFOTRIEVE]
  • Billion S., Tribout B., Cadet E., Queinnec C., Rochette J., Wheatley P., Bataille P. Hyperhomocysteinemia, folate and vitamin B12 in unsupplemented hemodialysis patients: effect of oral therapy with folic acid and vitamin B12. Nephrol. Dial. Transplant. 2002; 17(3)455–461, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Trimarchi H., Schiel A., Freixas E., Diaz M. Randomized trial of methylcobalamin and folate effects on homocysteine in hemodialysis patients. Nephron 2002; 91(1)58–63, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Lacour B., Parry C., Drueke T., Touam M., Kreis H., Bailly M., Durand D. Pyridoxal 5′‐phosphate deficiency in uremic undialyzed, hemodialyzed, and non‐uremic kidney transplant patients. Clin. Chim. Acta 1983; 127(2)205–215, [PUBMED], [INFOTRIEVE]
  • Said H. M., Vaziri N. D., Kariger R. K., Hollander D. Intestinal absorption of 5‐methyltetrahydrofolate in experimental uremia. Acta Vitaminol. Enzymol. 1984; 6(4)339–346, [PUBMED], [INFOTRIEVE]
  • Tremblay R., Bonnardeaux A., Geadah D., Busque L., Lebrun M., Ouimet D., Leblanc M. Hyperhomocysteinemia in hemodialysis patients: effects of 12‐month supplementation with hydrosoluble vitamins. Kidney Int. 2000; 58(2)851–858, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Buccianti G., Bamonti C. F., Patrosso C., Corghi E., Novembrino C., Baragetti I., Lando G., De Franceschi M., Maiolo A. T. Reduction of the homocysteine plasma concentration by intravenously administered folinic acid and vitamin B(12) in uraemic patients on maintenance haemodialysis. Am. J. Nephrol. 2001; 21(4)294–299, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Corghi E., Patrosso C., Bamonti F., Baragetti E., Novembrino C., Lando G., De Franceschi M., Buccianti G. Intravenous folinic acid and vitamin B12 supplementation and homocysteine concentration in hemodialysis patients. G. Ital. Nefrol. 2002; 19(3)301–307, [PUBMED], [INFOTRIEVE]

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