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Original Articles

Capillary Electrophoretic Separation and Quantitation of Ractopamine Stereoisomers Using Cyclodextrins as Chiral Additives

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Pages 1677-1693 | Received 10 Dec 2002, Accepted 15 Jan 2003, Published online: 06 Feb 2007

References

  • Wozniak , T. J. , Bopp , R. J. and Jensen , E. C. 1991 . Chiral drugs: an industrial analytical perspective . J. Pharm. Biomed. Anal. , 9 ( 5 ) : 363 – 382 .
  • Gassmann , E. , Guo , J. E. and Zare , R. N. 1985 . Electrokinetic separation of chiral compounds . Science , 230 ( 4727 ) : 813 – 814 .
  • Rogan , M. M. , Altria , K. D. and Goodall , D. M. 1994 . Enantioselective separations using capillary electrophoresis . Chirality , 6 : 25 – 40 .
  • Terabe , S. , Otsuka , K. and Nishi , H. 1994 . Separation of enantiomers by capillary electrophoretic techniques . J. Chromatogr. A , 666 ( 1–2 ) : 295 – 319 .
  • Rizzi , A. 2001 . Fundamental aspects of chiral separations by capillary electrophoresis . Electrophoresis , 22 ( 15 ) : 3079 – 3106 .
  • Amini , A. 2001 . Recent developments in chiral capillary electrophoresis and applications of this technique to pharmaceutical and biomedical analysis . Electrophoresis , 22 ( 15 ) : 3107 – 3130 .
  • Terabe , S. 1989 . Electrokinetic chromatography: an interface between electrophoresis and chromatography . Trends Anal. Chem. , 8 ( 4 ) : 129
  • Fanali , S. 1989 . Separation of optical isomers by capillary zone electrophoresis based on host‐guest complexation with cyclodextrins . J. Chromatogr. , 474 ( 2 ) : 441 – 446 .
  • Chankvetadze , B. , Endresz , G. and Blaschke , G. 1994 . About some aspects of the use of charged cyclodextrins for capillary electrophoresis enantiosepar‐ation . Electrophoresis , 15 : 804 – 807 .
  • Chankvetadze , B. , Endresz , G. , Bergenthal , D. and Blaschke , G. 1995 . Enantio‐separation of mianserine analogues using capillary electrophoresis with neutral and charged cyclodextrin buffer modifiers 13C NMR study of the chiral recognition mechanism . J. Chromatogr. A , 717 ( 1–2 ) : 245 – 253 .
  • Tait , R. J. , Thompson , D. O. and Stobaugh , J. F. 1994 . Sulfobutyl ether β‐cyclodextrin as a chiral discriminator for use with capillary electrophoresis . Anal. Chem. , 66 ( 22 ) : 4013 – 4018 .
  • Vincent , J. B. , Sokolowski , A. D. , Nguyen , T. V. and Vigh , G. 1997 . A family of single‐isomer chiral resolving agents for capillary electrophoresis1. Heptakis(2,3‐diacetyl‐6‐sulfato)‐β‐cyclodextrin . Anal. Chem. , 69 ( 20 ) : 4226 – 4233 .
  • Vincent , J. B. , Kirby , D. M. , Nguyen , T. V. and Vigh , G. 1997 . A family of single‐isomer chiral resolving agents for capillary electrophoresis2. hepta‐6‐sulfato‐β‐cyclodextrin . Anal. Chem. , 69 ( 21 ) : 4419 – 4428 .
  • Cai , H. , Nguyen , T. V. and Vigh , G. 1998 . A family of single‐isomer chiral resolving agents for capillary electrophoresis3. heptakis(2,3‐dimethyl‐6‐sulfato)‐β‐cyclodextrin . Anal. Chem. , 70 ( 3 ) : 580 – 589 .
  • Zhou , L. , Johnson , B. D. , Miller , C. and Wyvratt , J. M. 2000 . Chiral capillary electrophoretic analysis of the enantiomeric purity of a pharmaceutical compound using sulfated β‐cyclodextrin . J. Chromatogr. A , 875 ( 1–2 ) : 389 – 401 .
  • Tamisier‐Karolak , S. L. , Stenger , M.‐A. and Bommart , A. 1999 . Enantioseparation of β‐blockers with two chiral centers by capillary electrophoresis using sulfated β‐cyclodextrins . Electrophoresis , 20 ( 13 ) : 2656 – 2663 .
  • Wang , F. and Khaledi , M. G. 1999 . Capillary electrophoresis chiral separation of basic pharmaceutical enantiomers with different charges using sulfated β‐cyclodextrin . J. Micro. Sep. , 11 ( 1 ) : 11 – 21 .
  • Wang , F. , Dowling , T. , Bicker , G. and Wyvratt , J. 2001 . Electrophoretic chiral separation of pharmaceutical compounds with multiple stereogenic centers in charged cyclodextrin media . J. Sep. Sci. , 24 ( 5 ) : 378 – 384 .
  • 2000 . New Animal Drugs for Use in Animal Feeds; Ractopamine Hydrochloride Washington, D.C. : Federal Register; Department of Health and Human Services, Food and Drug Administration .
  • Watkins , L. E. , Jones , D. J. , Mowrey , D. H. , Anderson , D. B. and Veenhuizen , E. L. 1990 . The effect of various levels of ractopamine hydrochloride on the performance and carcass characteristics of finishing swine . J. Anim. Sci. , 68 ( 11 ) : 3588 – 3595 .
  • Stites , C. R. , McKeith , F. K. , Singh , S. D. , Bechtel , P. J. , Mowrey , D. H. and Jones , D. J. 1991 . The effect of ractopamine hydrochloride on the carcass cutting yields of finishing swine . J. Anim. Sci. , 69 ( 8 ) : 3094 – 3101 .
  • Ricke , E. A. , Smith , D. J. , Feil , V. J. , Larsen , G. L. and Caton , J. S. 1999 . Effects of ractopamine HCl stereoisomers on growth, nitrogen retention, and carcass composition in rats . J. Anim. Sci. , 77 : 701 – 707 .
  • Jorgenson , J. W. and Lukacs , K. D. 1981 . Zone electrophoresis in open‐tubular glass capillaries . Anal. Chem. , 53 : 1298 – 1302 .

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